Comet 81P/Wild 2 Under a Microscope (2006)
Brownlee, Don, Tsou, Peter, Aléon, Jérôme, Alexander, Conel M O'D, Araki, Tohru, Bajt, Sasa, ...
The Stardust spacecraft collected thousands of particles from comet 81P/Wild 2 and returned them to Earth for laboratory study. The preliminary examination of these samples shows that the nonvolatile...
MC1R, ASIP, and DNA Repair in Sporadic and Familial Melanoma in a Mediterranean Population (2005)
Landi, Maria Teresa, Kanetsky, Peter A., Tsang, Shirley, Gold, Bert, Munroe, David, Rebbeck, Timothy, ...
Background: Melanoma risk factors include fair pigmentation, multiple nevi, low DNA repair capacity, and CDKN2A or CDK4 mutations. Variants of the melanocortin-1 receptor (MC1R) gene have been...
Landi, Maria Teresa, Baccarelli, Andrea, Tarone, Robert E., Pesatori, Angela, Tucker, Margaret A., Hedayati, Mohammad, ...
Background: Exposure to UV radiation is associated with cutaneous malignant melanoma (CMM). In mammalian cells, UV radiation induces DNA damage that can be repaired by the nucleotide excision repair...
Landi, Maria Teresa, Baccarelli, Andrea, Pesatori, Angela C., Hedayati, Mohammad, Grossman, Lawrence, Tucker, Margaret A., ...
Rockenbauer, Eszter, Bendixen, Mette H., Bukowy, Zuzanna, Yin, Jiaoyang, Jacobsen, Nicklas R., Hedayati, Mohammad, ...
We have previously used single nucleotide polymorphisms to detect an association of basal cell carcinoma (BCC) in Caucasian Americans and Danes with the genome region 19q13.2-3, which contains...
Qiao, Yawei, Spitz, Margaret R., Shen, Hongbing, Guo, Zhaozheng, Shete, Sanjay, Hedayati, Mohammad, ...
DNA repair capacity (DRC) plays an important role in genetic susceptibility to cancer. Polymorphisms of a number of DNA repair genes involved in several distinct pathways have been identified....
Vogel, Ulla, Hedayati, Mohammad, Dybdahl, Marianne, Grossman, Lawrence, Nexø, Bjørn Andersen
The XPD gene product has a dual function in basal transcription and in nucleotide excision repair. We have previously reported that two polymorphisms in the gene, one silent mutation in codon 156 of...
A new xeroderma pigmentosum group C poly(AT) insertion/deletion polymorphism (2000)
Khan, Sikandar G., Metter, E.Jeffrey, Tarone, Robert E., Bohr, Vilhelm A., Grossman, Lawrence, Hedayati, Mohammad, ...
We found a common biallelic polymorphism (PAT) in the xeroderma pigmentosum complementation group C (XPC) DNA repair gene consisting of an insertion of 83 bases of A and T [poly(AT)] and a...
Article: Transformation Through Crisis: The American Jewish Committee and the Six-Day War (1998)
American Jewish History - Volume 86, Number 1, March 1998
DNA Repair and Susceptibility to Basal Cell Carcinoma: A Case-Control Study (1994)
Wei, Qingyi, Matanoski, Genevieve M., Farmer, Evan R., Hedayati, Mohammad A., Grossman, Lawrence
This study investigated the role of DNA repair in susceptibility to sunlight-induced basal cell carcinoma using a host cell reactivation assay in peripheral lymphocytes. The study included Maryland...
Hansson, Johan, Grossman, Lawrence, Lindahl, Tomas, Wood, Richard D.
A newly developed cell-free system was used to study DNA repair synthesis carried out by extracts from human cell lines in vitro. Extracts from a normal human lymphoid cell line and from cell lines...
Oh, Euk Y., Claassen, Lark, Thiagalingam, Sambasivamoorthy, Mazur, Sharlyn, Grossman, Lawrence
We have analyzed the ATPase activity exhibited by the UvrABC DNA repair complex. The UvrA protein is an ATPase whose lack of DNA dependence may be related to the ATP induced monomerdimer transitions....
Potential role of proteolysis in the control of UvrABC incision (1988)
Caron, Paul R., Grossman, Lawrence
UvrB is specifically proteolyzed in Escherichia coli cell extracts to UvrB*. UvrB* is capable of interacting with UvrA in an apparently similar manner to the UvrB, however UvtB* is defective in the...
Caron, Paul R., Grossman, Lawrence
The incision of damaged DNA by the Escherichia coli UvrABC endonuclease requires ATP hydrolysis. Although the deduced sequence of the UvtB protein suggests a putative ATP binding site, no nucleoside...
Yeung, Anthony T., Mattes, William B., Grossman, Lawrence
An examination has been made into the nature of the nucleoprotein complexes formed during the incision reaction catalyzed by the Escherichia coli UvrABC endonuclease when acting on a pyrimidine...
The purification of the Escherichia coliUvrABC incision system (1986)
Yeung, Anthony T., Mattes, William B., Oh, Euk Y., Yoakum, George H., Grossman, Lawrence
The UvrA, UvrB and UvrC proteins of Escherichia coli have been purified in good yields to homogeneity with rapid three- or four-step purification procedures. The cloned uvrA and uvrB genes were...
The effect of Escherichia coli Uvr protein binding on the topology of supercoiled DNA (1986)
Oh, Euk Y., Grossman, Lawrence
The effects of the binding of the E. coli UvrA and UvrB proteins on the linking number (ΔL) of superhelical DNA has been measured. The effects of cofactor ATP structure on UvrAB-nucleoprotein...
Condensation, chondrites and planets /--Lawrence Grossman. (1972)
Thesis (Ph. D.)--Yale University, 1972.
Nucleic acids / edited by Lawrence Grossman and Kivie Moldave (1967)
Grossman, Lawrence, Moldave, Kivie
Incluye bibliografía e índice
Potential role of proteolysis in the control of UvrABC incision
Caron, Paul R., Grossman, Lawrence
UvrB is specifically proteolyzed in Escherichia coli cell extracts to UvrB*. UvrB* is capable of interacting with UvrA in an aparently similar manner to the UvrB, however UvrB* is defective in the...
Involvement of a cryptic ATPase activity of UvrB and its proteolysis product, UvrB* in DNA repair
Caron, Paul R., Grossman, Lawrence
The incision of damaged DNA by the Escherichia coli UvrABC endonuclease requires ATP hydrolysis. Although the deduced sequence of the UvrB protein suggests a putative ATP binding site, no nucleoside...
In Vitro Repair of UV-Irradiated Micrococcus luteus Bacteriophage N1 Transfecting DNA 1
Mahler, Inga, George, Jeanne, Grossman, Lawrence
Calcium-treated UV-sensitive, host cell reactivation− strains of Micrococcus luteus are infected with UV-irradiated N1 DNA. In strains lacking UV endonuclease, in vitro treatment of the irradiated...
Braun, Andrew, Grossman, Lawrence
At least two endonucleolytic activities that preferentially incise ultraviolet (UV)-irradiated DNA exist in extracts of E. coli. These two activities can be separated by phosphocellulose...
Kaplan, Joan C., Kushner, Sidney R., Grossman, Lawrence
Two nucleases that catalyze the excision of photoproducts from UV-irradiated DNA have been extensively purified from M. luteus (M. lysodeikticus). The first enzyme, an endonuclease, has been purified...
Potential role of proteolysis in the control of UvrABC incision
Caron, Paul R., Grossman, Lawrence
UvrB is specifically proteolyzed in Escherichia coli cell extracts to UvrB*. UvrB* is capable of interacting with UvrA in an aparently similar manner to the UvrB, however UvrB* is defective in the...
Involvement of a cryptic ATPase activity of UvrB and its proteolysis product, UvrB* in DNA repair
Caron, Paul R., Grossman, Lawrence
The incision of damaged DNA by the Escherichia coli UvrABC endonuclease requires ATP hydrolysis. Although the deduced sequence of the UvrB protein suggests a putative ATP binding site, no nucleoside...
In Vitro Repair of UV-Irradiated Micrococcus luteus Bacteriophage N1 Transfecting DNA 1
Mahler, Inga, George, Jeanne, Grossman, Lawrence
Calcium-treated UV-sensitive, host cell reactivation− strains of Micrococcus luteus are infected with UV-irradiated N1 DNA. In strains lacking UV endonuclease, in vitro treatment of the irradiated...
Braun, Andrew, Grossman, Lawrence
At least two endonucleolytic activities that preferentially incise ultraviolet (UV)-irradiated DNA exist in extracts of E. coli. These two activities can be separated by phosphocellulose...
Kaplan, Joan C., Kushner, Sidney R., Grossman, Lawrence
Two nucleases that catalyze the excision of photoproducts from UV-irradiated DNA have been extensively purified from M. luteus (M. lysodeikticus). The first enzyme, an endonuclease, has been purified...