Scientific Commons: Lawrence M. Mylin

The assembly of functional {beta}2-microglobulin-free MHC class I molecules that interact with peptides and CD8+ T lymphocytes (2002)

Schell, Todd D., Mylin, Lawrence M., Tevethia, Satvir S., Joyce, Sebastian

Functional MHC class I molecules are expressed on the cell surface in the absence ofβ2‐microglobulin (β2m) light chain that can interact with CD8+ T lymphocytes. Whether their assembly...

Sequence conservation in the Saccharomyces and Kluveromyces GAL11 transcription acvivators suggests functional domains (1991)

Mylin, Lawrence M., Gerardot, Connie J., Hopper, James E., Dickson, Robert C.

Efficient transcription of many Saccharomyces cerevisiae genes requires the GAL11 Protein. GAL11 belongs to a class of transcription activator that lacks a DNA-binding domain. Such proteins are...

Phosphorylated forms of the transcriptional activator GAL4 closely correlate with GAL4-dependent transcription activation in saccharomyces cerevisiae / (1990)

Mylin, Lawrence M.

Thesis (Ph. D.)--Pennsylvania State University. The Milton S. Hershey Medical Center, 1990.

Immunization with a Single Major Histocompatibility Complex Class I-Restricted Cytotoxic T-Lymphocyte Recognition Epitope of Herpes Simplex Virus Type 2 Confers Protective Immunity

Blaney, Joseph E., Nobusawa, Eri, Brehm, Michael A., Bonneau, Robert H., Mylin, Lawrence M., Fu, Tong-Ming, ...

We have evaluated the potential of conferring protective immunity to herpes simplex virus type 2 (HSV-2) by selectively inducing an HSV-specific CD8+ cytotoxic T-lymphocyte (CTL) response directed...

Quantitation of CD8+ T-Lymphocyte Responses to Multiple Epitopes from Simian Virus 40 (SV40) Large T Antigen in C57BL/6 Mice Immunized with SV40, SV40 T-Antigen-Transformed Cells, or Vaccinia Virus Recombinants Expressing Full-Length T Antigen or Epitope Minigenes

Mylin, Lawrence M., Schell, Todd D., Roberts, Debra, Epler, Melanie, Boesteanu, Alina, Collins, Edward J., ...

The cytotoxic T-lymphocyte response to wild-type simian virus 40 large tumor antigen (Tag) in C57BL/6 (H2b) mice is directed against three H2-Db-restricted epitopes, I, II/III, and V, and one...

Cytotoxic T-Lymphocyte Epitope Immunodominance in the Control of Choroid Plexus Tumors in Simian Virus 40 Large T Antigen Transgenic Mice

Schell, Todd D., Mylin, Lawrence M., Georgoff, Ingo, Teresky, Angelica K., Levine, Arnold J., Tevethia, Satvir S.

The simian virus 40 (SV40) large tumor antigen (Tag) is a virus-encoded oncoprotein which is the target of a strong cytotoxic T-lymphocyte (CTL) response. Three immunodominant H-2b-restricted...

An Endoplasmic Reticulum-Targeting Signal Sequence Enhances the Immunogenicity of an Immunorecessive Simian Virus 40 Large T Antigen Cytotoxic T-Lymphocyte Epitope

Fu, Tong-Ming, Mylin, Lawrence M., Schell, Todd D., Bacik, Igor, Russ, Gustav, Yewdell, Jonathan W., ...

An immunological hierarchy among three H-2Db-restricted cytotoxic T lymphocyte (CTL) determinants in simian virus 40 (SV40) large T antigen (Tag) was described previously: determinants I and II/III...