Lea Novak

AL-amyloidosis is underdiagnosed in renal biopsies (2004)

Novak, Lea, Cook, William J., Herrera, Guillermo A., Sanders, Paul W.

Background. Renal amyloidosis is associated with a variety of underlying disease processes. Although amyloid is identical in appearance in these diseases, the precursor proteins are different....

AL-amyloidosis is underdiagnosed in renal biopsies (2004)

Novak, Lea, Cook, William J., Herrera, Guillermo A., Sanders, Paul W.

Background. Renal amyloidosis is associated with a variety of underlying disease processes. Although amyloid is identical in appearance in these diseases, the precursor proteins are different....

Nasal Colonization with Streptococcus pneumoniae Includes Subpopulations of Surface and Invasive Pneumococci

Briles, David E., Novak, Lea, Hotomi, Muneki, Van Ginkel, Frederik W., King, Janice

We demonstrated that during colonization with Streptococcus pneumoniae the nasal mucosal tissues of mice support two populations of pneumococci. Transparent-phase pneumococci can be readily washed...

Nasal Colonization with Streptococcus pneumoniae Includes Subpopulations of Surface and Invasive Pneumococci

Briles, David E., Novak, Lea, Hotomi, Muneki, Van Ginkel, Frederik W., King, Janice

We demonstrated that during colonization with Streptococcus pneumoniae the nasal mucosal tissues of mice support two populations of pneumococci. Transparent-phase pneumococci can be readily washed...

Human Breast Fibroblasts Inhibit Growth of the MCF10AT Xenograft Model of Proliferative Breast Disease

Sadlonova, Andrea, Mukherjee, Shibani, Bowe, Damon B., Gault, Sandra R., Dumas, Nicole A., Van Tine, Brian A., ...

Stromal fibroblasts are important for normal breast homeostasis and regulation of epithelial growth; however, this regulatory function is altered during carcinogenesis. To study the role of...

IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1

Suzuki, Hitoshi, Moldoveanu, Zina, Hall, Stacy, Brown, Rhubell, Vu, Huong L., Novak, Lea, ...

Aberrant glycosylation of IgA1 plays an essential role in the pathogenesis of IgA nephropathy. This abnormality is manifested by a deficiency of galactose in the hinge-region O-linked glycans of...

Macrophages in Vaginal but Not Intestinal Mucosa Are Monocyte-Like and Permissive to Human Immunodeficiency Virus Type 1 Infectionâ–ż

Shen, Ruizhong, Richter, Holly E., Clements, Ronald H., Novak, Lea, Huff, Kayci, Bimczok, Diane, ...

Mucosal surfaces play a major role in human immunodeficiency virus type 1 (HIV-1) transmission and pathogenesis, and yet the role of lamina propria macrophages in mucosal HIV-1 infection has received...