Leanne E. Wybenga-Groot

X-ray structure of the AAC(6')-Ii antibiotic resistance enzyme at 1.8 A resolution; examination of oligomeric arrangements in GNAT superfamily members (2003)

Burk, David L., Ghuman, Navleen, Wybenga-Groot, Leanne E., Berghuis, Albert M.

The rise of antibiotic resistance as a public health concern has led to increased interest in studying the ways in which bacteria avoid the effects of antibiotics. Enzymatic inactivation by several...

A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases

Wiesner, Silke, Wybenga-Groot, Leanne E, Warner, Neil, Lin, Hong, Pawson, Tony, Forman-Kay, Julie D, ...

Eph receptor tyrosine kinases (RTKs) mediate numerous developmental processes. Their activity is regulated by auto-phosphorylation on two tyrosines within the juxtamembrane segment (JMS) immediately...

X-ray structure of the AAC(6′)-Ii antibiotic resistance enzyme at 1.8 Å resolution; examination of oligomeric arrangements in GNAT superfamily members

Burk, David L., Ghuman, Navleen, Wybenga-Groot, Leanne E., Berghuis, Albert M.

The rise of antibiotic resistance as a public health concern has led to increased interest in studying the ways in which bacteria avoid the effects of antibiotics. Enzymatic inactivation by several...