Brumell, John H., Kujat-Choy, Sonya, Brown, Nathaniel Francis, Vallance, Bruce A., Knodler, Leigh A., Finlay, B. Brett
Salmonella typhimurium is a facultative intracellular pathogen that utilizes two type III secretion systems to deliver virulence proteins into host cells. These proteins, termed effectors, alter host...
Brumell, John H., Kujat-Choy, Sonya, Brown, Nathaniel Francis, Vallance, Bruce A., Knodler, Leigh A., Finlay, B. Brett
Salmonella typhimurium is a facultative intracellular pathogen that utilizes two type III secretion systems to deliver virulence proteins into host cells. These proteins, termed effectors, alter host...
Brumell, John H., Kujat-Choy, Sonya, Brown, Nathaniel Francis, Vallance, Bruce A., Knodler, Leigh A., Finlay, B. Brett
Salmonella typhimurium is a facultative intracellular pathogen that utilizes two type III secretion systems to deliver virulence proteins into host cells. These proteins, termed effectors, alter host...
Brumell, John H., Kujat-Choy, Sonya, Brown, Nathaniel Francis, Vallance, Bruce A., Knodler, Leigh A., Finlay, B. Brett
Salmonella typhimurium is a facultative intracellular pathogen that utilizes two type III secretion systems to deliver virulence proteins into host cells. These proteins, termed effectors, alter host...
McArthur, Andrew G., Knodler, Leigh A., Silberman, Jeffrey D., Davids, Barbara J., Gillin, Frances D., Sogin, Mitchell L.
A phylogenetic analysis of protein disulfide isomerase (PDI) domain evolution was performed with the inclusion of recently reported PDIs from the amitochondriate protist Giardia lamblia, yeast PDIs...
Pfeifer, Cheryl G., Marcus, Sandra L., Steele-Mortimer, Olivia, Knodler, Leigh A., Finlay, B. Brett
Survival and growth of salmonellae within host cells are important aspects of bacterial virulence. We have developed an assay to identify Salmonella typhimurium genes that are induced inside...
Vallance, Bruce A., Deng, Wanyin, Knodler, Leigh A., Finlay, B. Brett
The bacterial pathogen Citrobacter rodentium belongs to a family of gastrointestinal pathogens that includes enteropathogenic and enterohemorrhagic Escherichia coli and is the causative agent of...
The Salmonella Effector PipB2 Affects Late Endosome/Lysosome Distribution to Mediate Sif ExtensionV⃞
Knodler, Leigh A., Steele-Mortimer, Olivia
After internalization into mammalian cells, the bacterial pathogen Salmonella enterica resides within a membrane-bound compartment, the Salmonella-containing vacuole (SCV). During its maturation...
Knodler, Leigh A., Bestor, Aaron, Ma, Caixia, Hansen-Wester, Imke, Hensel, Michael, Vallance, Bruce A., ...
Plasmid vectors and fluorescent protein reporter systems are commonly used in the study of bacterial pathogenesis. Here we show that they can impair the ability of Salmonella enterica serovar...
Khan, Mohammed A., Ma, Caixia, Knodler, Leigh A., Valdez, Yanet, Rosenberger, Carrie M., Deng, Wanyin, ...
Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC) are noninvasive bacterial pathogens that infect their hosts' intestinal epithelium, causing severe diarrheal disease....
Pfeifer, Cheryl G., Marcus, Sandra L., Steele-Mortimer, Olivia, Knodler, Leigh A., Finlay, B. Brett
Survival and growth of salmonellae within host cells are important aspects of bacterial virulence. We have developed an assay to identify Salmonella typhimurium genes that are induced inside...
Vallance, Bruce A., Deng, Wanyin, Knodler, Leigh A., Finlay, B. Brett
The bacterial pathogen Citrobacter rodentium belongs to a family of gastrointestinal pathogens that includes enteropathogenic and enterohemorrhagic Escherichia coli and is the causative agent of...
The Salmonella Effector PipB2 Affects Late Endosome/Lysosome Distribution to Mediate Sif ExtensionV⃞
Knodler, Leigh A., Steele-Mortimer, Olivia
After internalization into mammalian cells, the bacterial pathogen Salmonella enterica resides within a membrane-bound compartment, the Salmonella-containing vacuole (SCV). During its maturation...
Knodler, Leigh A., Bestor, Aaron, Ma, Caixia, Hansen-Wester, Imke, Hensel, Michael, Vallance, Bruce A., ...
Plasmid vectors and fluorescent protein reporter systems are commonly used in the study of bacterial pathogenesis. Here we show that they can impair the ability of Salmonella enterica serovar...
Khan, Mohammed A., Ma, Caixia, Knodler, Leigh A., Valdez, Yanet, Rosenberger, Carrie M., Deng, Wanyin, ...
Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC) are noninvasive bacterial pathogens that infect their hosts' intestinal epithelium, causing severe diarrheal disease....
The Salmonella effector protein PipB2 is a linker for kinesin-1
Henry, Thomas, Couillault, Carole, Rockenfeller, Patrick, Boucrot, Emmanuel, Dumont, Audrey, Schroeder, Nina, ...
Understanding the mechanisms of Salmonella virulence is an important challenge. The capacity of this intracellular bacterial pathogen to cause diseases depends on the expression of virulence factors...
Salmonella Trafficking is Defined by Continuous Dynamic Interactions with the Endolysosomal System
Drecktrah, Dan, Knodler, Leigh A, Howe, Dale, Steele-Mortimer, Olivia
Following invasion of non-phagocytic host cells, Salmonella enterica survives and replicates within a phagosome-like compartment known as the Salmonella-containing vacuole (SCV). It is now well...
HilD-mediated transcriptional cross-talk between SPI-1 and SPI-2
Bustamante, Víctor H., Martínez, Luary C., Santana, Francisco J., Knodler, Leigh A., Steele-Mortimer, Olivia, Puente, José L.
The acquisition of new genetic traits by horizontal gene transfer and their incorporation into preexisting regulatory networks have been essential events in the evolution of bacterial pathogens. An...
Dynamic Behavior of Salmonella-Induced Membrane Tubules in Epithelial Cells
Drecktrah, Dan, Levine-Wilkinson, Seamus, Dam, Tapen, Winfree, Seth, Knodler, Leigh A, Schroer, Trina A, ...
Salmonella Typhimurium is a facultative intracellular pathogen that causes acute gastroenteritis in man. Intracellular Salmonella survive and replicate within a modified phagosome known as the...
Knodler, Leigh A, Winfree, Seth, Drecktrah, Dan, Ireland, Robin, Steele-Mortimer, Olivia
The Salmonella type III effector, SopB, is an inositol polyphosphate phosphatase that modulates host cell phospholipids at the plasma membrane and the nascent Salmonella-containing vacuole (SCV)....