Chan, Queenie WT, Melathopoulos, Andony P, Pernal, Stephen F, Foster, Leonard J
Abstract Background There is a major paradox in our understanding of honey bee immunity: the high population density in a bee colony implies a high rate of disease transmission among individuals, yet...
Resource A Mammalian Organelle Map by Protein Correlation Profiling (2009)
Leonard J. Foster, Yanling Zhang, Yong Zhang, Xiaohui Xie, Vamsi K. Mootha, ...
Protein localization to membrane-enclosed organelles is a central feature of cellular organization. Using protein correlation profiling, we have mapped 1,404 proteins to ten subcellular locations in...
Changes in protein expression during honey bee larval development (2008)
Chan, Queenie WT, Foster, Leonard J
Abstract Background The honey bee ( Apis mellifera ), besides its role in pollination and honey production, serves as a model for studying the biochemistry of development, metabolism, and immunity in...
Proteomic analysis of the secretome of Leishmania donovani (2008)
Silverman, J Maxwell, Chan, Simon K, Robinson, Dale P, Dwyer, Dennis M, Nandan, Devki, Foster, Leonard J, ...
Abstract Background Leishmania and other intracellular pathogens have evolved strategies that support invasion and persistence within host target cells. In some cases the underlying mechanisms...
Howes, Charles G, Foster, Leonard J
Abstract Background Technological advances in mass spectrometry and other detection methods are leading to larger and larger proteomics datasets. However, when papers describing such information are...
MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes (2007)
Zhang, Yanling, Zhang, Yong, Adachi, Jun, Olsen, Jesper V., Shi, Rong, De Souza, Gustavo, ...
Mass spectrometry (MS)-based proteomics has become a powerful technology to map the protein composition of organelles, cell types and tissues. In our department, a large-scale effort to map these...
MAPU: Max-Planck Unified database of organellar, (2006)
Yanling Zhang, Yong Zhang, Jun Adachi, Jesper V. Olsen, Rong Shi, Gustavo De Souza, ...
cellular, tissue and body fluid proteomes
MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes (2006)
Zhang, Yanling, Zhang, Yong, Adachi, Jun, Olsen, Jesper V., Shi, Rong, De Souza, Gustavo, ...
Mass spectrometry (MS)-based proteomics has become a powerful technology to map the protein composition of organelles, cell types and tissues. In our department, a large-scale effort to map these...
MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes (2006)
Zhang, Yanling, Zhang, Yong, Adachi, Jun, Olsen, Jesper V., Shi, Rong, De Souza, Gustavo, ...
Mass spectrometry (MS)-based proteomics has become a powerful technology to map the protein composition of organelles, cell types and tissues. In our department, a large-scale effort to map these...
Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors
Foster, Leonard J., De Hoog, Carmen L., Mann, Matthias
Membrane lipids were once thought to be homogenously distributed in the 2D surface of a membrane, but the lipid raft theory suggests that cholesterol and sphingolipids partition away from other...
Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors
Foster, Leonard J., De Hoog, Carmen L., Mann, Matthias
Membrane lipids were once thought to be homogenously distributed in the 2D surface of a membrane, but the lipid raft theory suggests that cholesterol and sphingolipids partition away from other...
MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes
Zhang, Yanling, Zhang, Yong, Adachi, Jun, Olsen, Jesper V., Shi, Rong, De Souza, Gustavo, ...
Mass spectrometry (MS)-based proteomics has become a powerful technology to map the protein composition of organelles, cell types and tissues. In our department, a large-scale effort to map these...
Proteomic analysis of the secretome of Leishmania donovani
Silverman, J Maxwell, Chan, Simon K, Robinson, Dale P, Dwyer, Dennis M, Nandan, Devki, Foster, Leonard J, ...
Analysis of Leishmania-conditioned medium resulted in the identification of 151 proteins apparently secreted by the parasitic protozoan Leishmania donovani and suggested a vesicle-based secretion...
The dynamic phagosomal proteome and the contribution of the endoplasmic reticulum
Rogers, Lindsay D., Foster, Leonard J.
Macrophages use phagocytosis to control the spread of pathogens in the body, to clear apoptotic cells, and to aid in tissue remodeling. The phagosomal membrane is traditionally thought to originate...
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization
Fielding, Andrew B., Dobreva, Iveta, McDonald, Paul C., Foster, Leonard J., Dedhar, Shoukat
Integrin-linked kinase (ILK) is a serine-threonine kinase and scaffold protein with well defined roles in focal adhesions in integrin-mediated cell adhesion, spreading, migration, and signaling....
Contributions of proteomics to understanding phagosome maturation
Rogers, Lindsay D, Foster, Leonard J
In metazoans macrophage cells use phagocytosis, the process of engulfing large particles, to control the spread of pathogens in the body, to clear dead or dying cells, and to aid in tissue...
Kwok, Michael C. M., Holopainen, Juha M., Molday, Laurie L., Foster, Leonard J., Molday, Robert S.
The outer segment is a specialized compartment of vertebrate rod and cone photoreceptor cells where phototransduction takes place. In rod cells it consists of an organized stack of disks enclosed by...
Contributions of quantitative proteomics to understanding membrane microdomains
Zheng, Yu Zi, Foster, Leonard J.
Membrane microdomains, e.g., lipid rafts and caveolae, are crucial cell surface organelles responsible for many cellular signaling and communication events, which makes the characterization of their...