Leonidas G. Koniaris

Should Informed Consent for Cancer Treatment Include a Discussion about Hospital Outcome Disparities? (2008)

Nadine Housri, Robert J. Weil, David I. Shalowitz, Leonidas G. Koniaris

Background to the debate: Several studies have found disparities in the outcome of medical procedures across different hospitals—better outcomes have been associated with higher procedure volume....

Lethal Injection for Execution: Chemical Asphyxiation? (2007)

Teresa A. Zimmers, Jonathan Sheldon, David A. Lubarsky, Francisco López-Muñoz, Linda Waterman, Richard Weisman, ...

BackgroundLethal injection for execution was conceived as a comparatively humane alternative to electrocution or cyanide gas. The current protocols are based on one improvised by a medical examiner...

MIC-1, A Potential Inhibitor of Breast Tumor Progression (1998)

Koniaris, Leonidas G.

MIC-l is a member of the transforming growth factor-beta family of growth and differentiation factors. MIC-l is expressed in breast tissue and has numerous specific effects including inhibiting both...

MIC-1, A Potential Inhibitor of Breast Tumor Progression (1998)

Koniaris, Leonidas G.

MIC-1/GDF-l5 is a newly identified member of the TGF-beta superfamily of growth and differentiation factors. MIC-1/GDF-15 is highly expressed in both animal models and patients with breast cancer....

Characterization of Growth-Differentiation Factor 15, a Transforming Growth Factor β Superfamily Member Induced following Liver Injury

Hsiao, Edward C., Koniaris, Leonidas G., Zimmers-Koniaris, Teresa, Sebald, Suzanne M., Huynh, Thanh V., Lee, Se-Jin

We have identified a new murine transforming growth factor β superfamily member, growth-differentiation factor 15 (Gdf15), that is expressed at highest levels in adult liver. As determined by...

507 Warren-Zeppa Distal Splenorenal Shunts: A 34-Year Experience

Livingstone, Alan S., Koniaris, Leonidas G., Perez, Eduardo A., Alvarez, Nicholas, Levi, Joe U., Hutson, Duane G.

The Warren-Zeppa shunt provides long-term survival and control of bleeding in most patients with portal hypertension. Based upon a 34-year follow-up of 507 patients we conclude excellent long-term...

Characterization of Growth-Differentiation Factor 15, a Transforming Growth Factor β Superfamily Member Induced following Liver Injury

Hsiao, Edward C., Koniaris, Leonidas G., Zimmers-Koniaris, Teresa, Sebald, Suzanne M., Huynh, Thanh V., Lee, Se-Jin

We have identified a new murine transforming growth factor β superfamily member, growth-differentiation factor 15 (Gdf15), that is expressed at highest levels in adult liver. As determined by...

507 Warren-Zeppa Distal Splenorenal Shunts: A 34-Year Experience

Livingstone, Alan S., Koniaris, Leonidas G., Perez, Eduardo A., Alvarez, Nicholas, Levi, Joe U., Hutson, Duane G.

The Warren-Zeppa shunt provides long-term survival and control of bleeding in most patients with portal hypertension. Based upon a 34-year follow-up of 507 patients we conclude excellent long-term...

Lethal Injection for Execution: Chemical Asphyxiation?

Zimmers, Teresa A, Sheldon, Jonathan, Lubarsky, David A, López-Muñoz, Francisco, Waterman, Linda, Weisman, Richard, ...

Data from executions in the US suggest that current lethal injection protocols do not effect death through the mechanisms intended, and that potentially aware inmates could die through...

Should Soft Tissue Sarcomas Be Treated at High-volume Centers?: An Analysis of 4205 Patients

Gutierrez, Juan C., Perez, Eduardo A., Moffat, Frederick L., Livingstone, Alan S., Franceschi, Dido, Koniaris, Leonidas G.

Using a large prospective cancer registry, the effects of surgical volume on patient outcomes for soft tissue sarcoma were examined. A significantly increased overall short-term and long-term...

Ethical Implications of Modifying Lethal Injection Protocols

Koniaris, Leonidas G, Goodman, Kenneth W, Sugarman, Jeremy, Ozomaro, Uzoezi, Sheldon, Jonathan, Zimmers, Teresa A

Teresa Zimmers and colleagues argue that it is difficult to conceive how lethal injection research activities could be carried out in a fashion consistent with ethical norms.

Should Informed Consent for Cancer Treatment Include a Discussion about Hospital Outcome Disparities?

Housri, Nadine, Weil, Robert J, Shalowitz, David I, Koniaris, Leonidas G

Background to the debate: Several studies have found disparities in the outcome of medical procedures across different hospitals—better outcomes have been associated with higher procedure volume....