Large-scale modeling of parametric surfaces using spherical harmonics (2009)
We present an approach for large-scale modeling of parametric surfaces using spherical harmonics (SHs). A standard least square fitting (LSF) method for SH expansion is not scalable and cannot...
Li Shen, James Ford, Fillia Makedon, Andrew Saykin
We present a new technique for 3D surface object classification that combines a powerful shape representation approach with suitable pattern classification techniques. Spherical harmonic...
K-means+ Method for Improving Gene Selection for Classification of Microarray Data (2009)
Heng Huang, Rong Zhang, Fei Xiong, Fillia Makedon, Li Shen
Microarray gene expression techniques have recently made it possible to offer phenotype classification of many diseases. One problem in this analysis is that each sample is represented by quite a...
Rao, Xiancai, Deighan, Padraig, Hua, Ziyu, Hu, Xiaomei, Wang, Jin, Luo, Miao, ...
The obligate intracellular human pathogen Chlamydia trachomatis undergoes a complex developmental program involving transition between two forms: the infectious elementary body (EB), and the rapidly...
• Creating a table of powers • Function declarations from the compiler’s viewpoint • An alternate style for function definition order
Li Shen, Andrew Saykin, Tara Mchugh, John West, Laura Rabin, Heather Wishart, ...
A computational framework is presented for morphometric analysis of 3D surfaces that aims to localize regionally specific shape changes between groups of 3D objects. This framework integrates a set...
Cardiac motion analysis to improve pacing site selection in CRT. Acad Radiol 2006 (2008)
Heng Huang, Li Shen, Rong Zhang, Fillia Makedon, Bruce Hettleman, Justin Pearlman
Rationale and Objectives: The aim of the study is to build cardiac wall motion models to characterize mechanical dyssynchrony and predict pacing sites for the left ventricle of the heart in cardiac...
A Multimedia System for the Anatomical Study of Brain Images (2008)
Li Shen, Ling Cheng, Faye Teng, Fillia Makedon, James Ford, Tilmann Steinberg, ...
We develop a multimedia system to support the whole process of the anatomical study of brain images. The system provides a segmentation tool to extract regions-of-interest from brain images, an...
Abstract Background Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering regulatory...
Modeling Time-Intensity Profiles for Pulmonary Nodules in MR Images (2008)
Li Shen, Wei Zheng, Ling Gao, Heng Huang, Fillia Makedon, Justin Pearlman
Abstract — Perfusion magnetic resonance imaging (pMRI) is an important tool to assess tumor angiogenesis for the early detection of lung cancer. This paper presents a novel integrated framework for...
Shen, Li, Shui, Yongjie, Wang, Xiaojia, Sheng, Liming, Yang, Zhengyan, Xue, Danfeng, ...
Abstract Background Proteins overexpressed on the surface of tumor cells can be selectively targeted. Epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) are...
Resistant starch (RS) is fermentable dietary fiber. It has been shown that inclusion of resistant starch in the diet causes decreased body fat accumulation and altered gut hormone profile. Gut...
Resistant starch (RS) is fermentable dietary fiber. It has been shown that inclusion of resistant starch in the diet causes decreased body fat accumulation and altered gut hormone profile. Gut...
Accurate cancer prediction is important for treatment of cancers. The combination of two dimension reduction methods, partial least squares (PLS) and singular value decomposition (SVD), with the...
A GENERALIZED OUTPUT-CODING SCHEME WITH SVM FOR MULTICLASS MICROARRAY CLASSIFICATION (2008)
Multiclass cancer classification based on microarray data is described. A generalized output-coding scheme combined with binary classifiers is used. Different coding strategies, decoding functions...
Introduction Mining the Most Interesting Web Access Associations (2008)
Li Shen, Ling Cheng, James Ford, Fillia Makedon, Vasileios Megalooikonomou, Tilmann Steinberg
A Spatio-temporal Modeling Method for Shape Representation (2008)
Heng Huang, Li Shen, Rong Zhang, Fillia Makedon, Justin Pearlman
The spherical harmonic (SPHARM) description is a powerful surface modeling technique that can model arbitrarily shaped but simply connected three dimensional (3D) objects. Because SPHARM based 3D...
IGARASHI T.: Illumination brush: Interactive design of all-frequency lighting (2008)
Makoto Okabe, Yasuyuki Matsushita, Li Shen, Takeo Igarashi
We present an appearance-based user interface for artists to efficiently design customized image-based lighting environments. 1 Our approach avoids typical iterations of parameter editing, rendering,...
Hemispherical Harmonic Surface Description and Applications to Medical Image Analysis (2008)
Heng Huang, Lei Zhang, Dimitris Samaras, Li Shen, Rong Zhang, Fillia Makedon, ...
The use of surface harmonics for rigid and nonrigid shape description is well known. In this paper we define a set of complete hemispherical harmonic basis functions on a hemisphere domain and...
Spatial Distributions of Legacy Contaminants in Sediments of Lakes Huron and Superior (2008)
Sarah B. Gewurtz, Li Shen, Paul A. Helm, Jasmine Waltho, Eric J. Reiner, Scott Painter, ...
The sediments of Lake Superior, Lake Huron, and Georgian Bay were sampled in 2001 and 2002 in order to evaluate the extent of surficial sediment contamination of polychlorinated biphenyls (PCBs),...
Heng Huang, Fillia Makedon, James Ford, Li Shen, Yuhang Wang, Tilmann Steinberg, ...
The spherical harmonics (SPHARM) approach has been used for the representation of shapes in many types of biomedical image data. We propose a SPHARM-based similarity comparison for shape sequences...
Introduction Mining the Most Interesting Web Access Associations (2008)
Li Shen, Ling Cheng, James Ford, Fillia Makedon, Vasileios Megalooikonomou, Tilmann Steinberg
Multi-scale Voxel-based Morphometry via Weighted Spherical Harmonic Representation (2008)
Moo K. Chung, Li Shen, Kim M. Dalton, Richard J. Davidson
Abstract. Although the voxel-based morphometry (VBM) has been widely used in quantifying the amount of gray matter of the human brain, the optimal amount of registration that should be used in VBM...
Tracking Resource Usage Using Heterogeneous Feature Spaces with Local Exceptions (2008)
Tilmann Steinberg, James Ford, Yi Ouyang, Li Shen, Yuhang Wang, Fillia Makedon
Abstract. We describe a method for tracking usage of resources in a web environment by representing the resources as a feature space in which usage instances appear as trails, so that common access...
Bis(1,2,3,4-tetrahydroquinolin-6-yl)methane (2008)
The asymmetric unit of the title compound, C19H22N2, contains one half-molecule. The 1,2,3,4-tetrahydroquinoline units are linked by a methylene bridge, which lies on a twofold rotation axis. The...
Life cycle assessment of polysaccharide materials: a review (2008)
Apart from conventional uses of polysaccharide materials, such as food, clothing, paper packaging and construction, new polysaccharide products and materials have been developed. This paper reviews...
using a Gibbs sampler enhanced Bayesian network approach (2008)
GBNet: Deciphering regulatory rules in the co-regulated genes
1 Wavelet Based Image Compression System 1 (2007)
In this project, we developed a wavelet based image compression system primarily for grayscale images. After wavelet transformation, subbands with similar statistical characteristics are grouped as a...
Of Gray Matter, Moo K. Chung, Kim M. Dalton, Li Shen, Alan C. Evans, Richard J. Davidson
representation for cortical surfaces. The WFS representation is a data smoothing technique that provides the explicit smooth functional estimation of unknown cortical boundary as a linear combination...
Wild-type early activity of the adenovirus 5 E1b gene promoter requires readthrough transcription originated from the adjacent upstream E1a gene. This unusual mode of viral transcription activation...
The full text of the dissertation is available as a Adobe Acrobat .pdf file (137 p.) ; Adobe Acrobat Reader required to view the file.
Thesis (Ph.D.)--Pennsylvania State University, 2006.
Li Shen, Andrew J. Saykin, Moo K. Chung, Heng Huang, James Ford, Fillia Makedon, ...
We study the connection between genotype and imaging phenotype in order to detect possible genetic risk factors in mild cognitive impairment (MCI) and Alzheimer’s disease (AD). We focus on...
Large-scale modeling of parametric surfaces using spherical harmonics (2006)
We present an approach for large-scale modeling of parametric surfaces using spherical harmonics (SHs). A standard least square fitting (LSF) method for SH expansion is not scalable and cannot...
Multi-scale Voxel-based Morphometry via Weighted Spherical Harmonic Representation (2006)
Moo K. Chung, Li Shen, Kim M. Dalton, Richard J. Davidson, Moo K. Chung, Li Shen, ...
Abstract. Although the voxel-based morphometry (VBM) has been widely used in quantifying the amount of gray matter of the human brain, the optimal amount of registration that should be used in VBM...
Unified Cortical Surface Morphometry and Its Application to Quantifying Amount of Gray Matter (2006)
Moo K. Chung, Moo K. Chung, Kim M. Dalton, Li Shen, Alan C. Evans, Richard J. Davidson
In quantifying the amount of gray matter in a population, voxelbased morphometry (VBM) and cortical thickness analysis are the two most widely used techniques. There are still many unanswered...
Li Shen, Andrew J. Saykin, Moo K. Chung, Heng Huang, James Ford, Fillia Makedon, ...
We study the connection between genotype and imaging phenotype in order to detect possible genetic risk factors in mild cognitive impairment (MCI) and Alzheimer’s disease (AD). We focus on...
Weighted spherical harmonic representation and its application to cortical analysis (2006)
Steven M. Robbins, Moo K. Chung, Moo K. Chung, Li Shen, Li Shen, Kim M. Dalton, ...
Abstract. We present a novel weighted spherical harmonic (SPHARM) representation of cortical surfaces and its application to a cortical thickness analysis in autism. The weighted-SPHARM is a...
Hu, Guohong, Wang, Hui-Yun, Greenawalt, Danielle M., Azaro, Marco A., Luo, Minjie, Tereshchenko, Irina V., ...
Microarray-based analysis of single nucleotide polymorphisms (SNPs) has many applications in large-scale genetic studies. To minimize the influence of experimental variation, microarray data usually...
Identification of surface-exposed components of MOMP of Chlamydia trachomatis serovar F (2006)
Wang, Yan, Berg, Eric A., Feng, Xiaogeng, Shen, Li, Smith, Temple, Costello, Catherine E., ...
The identification of surface-exposed components of the major outer membrane protein (MOMP) of Chlamydia is critical for modeling its three-dimensional structure, as well as for understanding the...
Hu, Guohong, Wang, Hui-Yun, Greenawalt, Danielle M., Azaro, Marco A., Luo, Minjie, Tereshchenko, Irina V., ...
Microarray-based analysis of single nucleotide polymorphisms (SNPs) has many applications in large-scale genetic studies. To minimize the influence of experimental variation, microarray data usually...
Hu, Guohong, Wang, Hui-Yun, Greenawalt, Danielle M., Azaro, Marco A., Luo, Minjie, Tereshchenko, Irina V., ...
Microarray-based analysis of single nucleotide polymorphisms (SNPs) has many applications in large-scale genetic studies. To minimize the influence of experimental variation, microarray data usually...
Huang, Heng, Shen, Li, Zhang, Rong, Makedon, Fillia, Pearlman, Justin
We propose a novel framework at MICCAI 2005 to predict pacing sites in the left ventricle (LV) of a heart. This framework can be used to assist pacemaker implantation and programming in cardiac...
Surface Alignment of 3D Spherical Harmonic Models: Application to Cardiac MRI Analysis (2005)
Heng Huang, Li Shen, Fillia Makedon, Bruce Hettleman, Justin Pearlman
Abstract. The spherical harmonic (SPHARM) description is a powerful surface modeling technique that can model arbitrarily shaped but simply connected 3D objects and has been used in many applications...
A Prediction Framework for Cardiac Resynchronization Therapy Via 4D Cardiac Motion Analysis (2005)
Heng Huang, Li Shen, Fillia Makedon, Bruce Hettleman, Justin Pearlman
Abstract. We propose a novel framework to predict pacing sites in the left ventricle (LV) of a heart and its result can be used to assist pacemaker implantation and programming in cardiac...
Wang, Hui-Yun, Luo, Minjie, Tereshchenko, Irina V., Frikker, Danielle M., Cui, Xiangfeng, Li, James Y., ...
A high-throughput genotyping system for scoring single nucleotide polymorphisms (SNPs) has been developed. With this system, >1000 SNPs can be analyzed in a single assay, with a sensitivity that...
Greenawalt, Danielle M., Cui, Xiangfeng, Wu, Yujun, Lin, Yong, Wang, Hui-Yun, Luo, Minjie, ...
Although the haplotype structure of the human genome has been studied in great detail, very little is known about the mechanisms underlying its formation. To investigate the role of meiotic...
Manufacturing of high performance, low cost dual mirror lamp reflector modules / (2004)
Thesis (Ph. D.)--Stony Brook University, 2004.
Yuhang Wang, Fillia Makedon, James Ford, Li Shen, Dina Goldin
Automatic generation of semantic metadata describing spatial relations is highly desirable for image digital libraries. Relative spatial relations between objects in an image convey important...
surface-based approach for classification of 3d neuroanatomical structures (2004)
Li Shen, James Ford, Fillia Makedon, Andrew Saykin
We present a new framework for 3D surface object classification that combines a powerful shape description method with suitable pattern classification techniques. Spherical harmonic parameterization...
Yuhang Wang, Fillia Makedon, James Ford, Li Shen, Dina Goldin
Automatic generation of semantic metadata describing spatial relations is highly desirable for image digital libraries. Relative spatial relations between objects in an image convey important...
Tilmann Steinberg, Yuhang Wang, Fillia Makedon, Li Shen, Andrew Saykin, Heather Wishart
We describe the development of a system that automates data collection, metadata extraction and analysis of spatio-temporal multi-modal data, combining data management and data analysis to provide an...
Fillia Makedon, Yuhang Wang, Tilmann Steinberg, Heather Wishart, Andrew Saykin, James Ford, ...
Abstract- This paper describes the development of MS-Analyze, a system framework to analyze and detect patterns in brain pathology of multiple sclerosis (MS) as the disease progresses over time. We...
Morphometric analysis of brain structures for improved discrimination (2003)
Li Shen, James Ford, Fillia Makedon, Yuhang Wang, Tilmann Steinberg, Song Ye, ...
Abstract. We perform discriminative analysis of brain structures using morphometric information. Spherical harmonics technique and point distribution model are used for shape description....
SCENS: a System for the Mediated Sharing of Sensitive Data (2003)
Song Ye Fillia, Song Ye, Fillia Makedon, Tilmann Steinberg, Li Shen, James Ford, ...
This paper introduces SCENS, a Secure Content Exchange Negotiation System suitable for the exchange of private digital data that reside in distributed digital repositories. SCENS is an open...
Tilmann Steinberg, Yuhang Wang, Fillia Makedon, Li Shen, Andrew Saykin, Heather Wishart
We describe the development of a system that automates data collection, metadata extraction and analysis of spatio-temporal multi-modal data, combining data management and data analysis to provide an...
Data Brokers: Building Collections Through Automated Negotiation (2003)
Fillia Makedon, Song Ye, Sheng Zhang, James Ford, Li Shen, Sarantos Kapidakis
Abstract. Collecting digital materials is time-consuming and can gain from automation. Since each source – and even each acquisition – may involve a separate negotiation of terms, a collector may...
Surface-based morphometric analysis for hippocampal shape (2003)
Abstract—A computational framework is presented for surface based morphometry to localize shape changes between groups of 3D objects. It employs the spherical harmonic (SPHARM) method for surface...
Data Brokers: Building Collections Through Automated Negotiation (2003)
Fillia Makedon, Song Ye, Sheng Zhang, James Ford, Li Shen, Sarantos Kapidakis
Abstract. Collecting digital materials is time-consuming and can gain from automation. Since each source—and even each acquisition—may involve a separate negotiation of terms, a collector may...
Functional Testing of LSI/VLSI (Very Large Scale Integration) Digital Systems. (2002)
Su,Stephen Y. H., Lin,Tony S., Shen,Li
Due to the advances in the integrated circuit (IC) technology, more and more components are being fabricated into a tiny IC chip. Since the number of pins on each chip is limited by the physical size...
Functional Testing of LSI/VLSI Based Systems with Measure of Fault Coverage. (2002)
This paper presents a method for functional testing of microprocessors. First, we develop a control fault model at the RTL (Register Transfer Language) level. Based on this model, we establish...
Evaluation Metrics for Usercentered Ranking of Content (2002)
James Ford, Fillia Makedon, Li Shen, Tilmann Steinberg, Andrew Saykin, Heather Wishart
MetaDL: A Digital Library of Metadata for Sensitive or (2002)
Fillia Makedon, James Ford, Li Shen, Tilmann Steinberg, Sarantos Kapidakis, Andrew Saykin, ...
Abstract: Traditional digital library systems have difficulties when managing heterogeneous datasets that have limitations on their distribution. Collections of digital libraries have to be accessed...
Fast Association discovery in Derivative transaction collections (2000)
Shen, Li, Shen, Hong, Cheng, Ling, Pritchard, Paul Andrew
Yes
Fast Association discovery in Derivative transaction collections (2000)
Shen, Li, Shen, Hong, Cheng, Ling, Pritchard, Paul Andrew
Yes
Data mining in brain imaging (2000)
Vasileios Megalooikonomou, James Ford, Li Shen
Data mining in brain imaging is proving to be an effective methodology for disease prognosis and prevention. This, together with the rapid accumulation of massive heterogeneous data sets, motivates...
Data mining in brain imaging (2000)
Fillia Makedon, Andrew Saykin, Vasileios Megalooikonomou, Vasileios Megalooikonomou, James Ford, James Ford, ...
Data mining in brain imaging is proving to be an effective methodology for disease prognosis and prevention. This, together with the rapid accumulation of massive heterogeneous data sets, motivates...
Thesis (M.S.)--Drexel University, 1999.
Mining the Most Interesting Web Access Associations (1999)
Li Shen, Ling Cheng, James Ford, Fillia Makedon, Vasileios Megalooikonomou, Tilmann Steinberg
: Web access patterns can provide valuable information for website designers in making website-based communication more efficient. To extract interesting or useful web access patterns, we use data...
Potential carcinogenic mechanisms for premarin estrogens / (1998)
Thesis (Ph. D. in medicinal chemistry)--University of Illinois at Chicago, 1998.
Typescript.
Typescript.
Thesis (Ph.D.)--New York University, 1996.
This is a comparative study of the use of figurative language in Chinese L1 and English L2 texts written by eight Mandarin-speaking advanced students recruited from a university in Shanghai, People's...
p-Quinone methides are the major decomposition products of catechol estrogen o-quinones (1996)
The mechanism of catechol estrogen-induced cardnogenesis could involve alkylation of critical cellular macromolecules by electrophilic quinoids. The o-quinones formed from peroxidase/P450-catalyzed...
On SOV structure in contemporary Mandarin Chinese (1990)
Linguists neglect the SOV structure because they assume that the BA-construction is the only SOV form in Chinese and SOV word order is only a means of contrast and emphasis. The current study proves...
On SOV structure in contemporary Mandarin Chinese / (1990)
Thesis (Ph. D.)--University of Nebraska--Lincoln, 1990.
On SOV structure in contemporary Mandarin Chinese / (1990)
Thesis (Ph. D.)--University of Nebraska--Lincoln, 1990.
Local Character of Readthrough Activation in Adenovirus Type 5 Early Region 1 Transcription Control
Wild-type early activity of the adenovirus 5 E1b gene promoter requires readthrough transcription originating from the adjacent upstream E1a gene. This unusual mode of viral transcription activation...
Wang, Hui-Yun, Luo, Minjie, Tereshchenko, Irina V., Frikker, Danielle M., Cui, Xiangfeng, Li, James Y., ...
A high-throughput genotyping system for scoring single nucleotide polymorphisms (SNPs) has been developed. With this system, >1000 SNPs can be analyzed in a single assay, with a sensitivity that...
Lang, Mark L, Chen, Yih-Wen, Shen, Li, Gao, Hong, Lang, Gillian A, Wade, Terri K, ...
The human IgA Fc receptor (FcalphaR, CD89) triggers several important physiological functions, including phagocytosis, NADPH oxidase activation and antigen presentation. Efforts are underway to...
Herrera, Victoria LM, Shen, Li, Lopez, Lyle V, Didishvili, Tamara, Zhang, You-Xun, Ruiz-Opazo, Nelson
Chlamydia pneumoniae (Cpn) has been associated with human coronary artery disease but causal relevance as a risk factor has not been shown. Several rabbit and mouse model studies demonstrate...
Greenawalt, Danielle M., Cui, Xiangfeng, Wu, Yujun, Lin, Yong, Wang, Hui-Yun, Luo, Minjie, ...
Although the haplotype structure of the human genome has been studied in great detail, very little is known about the mechanisms underlying its formation. To investigate the role of meiotic...
Hu, Guohong, Wang, Hui-Yun, Greenawalt, Danielle M., Azaro, Marco A., Luo, Minjie, Tereshchenko, Irina V., ...
Microarray-based analysis of single nucleotide polymorphisms (SNPs) has many applications in large-scale genetic studies. To minimize the influence of experimental variation, microarray data usually...
Local Character of Readthrough Activation in Adenovirus Type 5 Early Region 1 Transcription Control
Wild-type early activity of the adenovirus 5 E1b gene promoter requires readthrough transcription originating from the adjacent upstream E1a gene. This unusual mode of viral transcription activation...
Wang, Hui-Yun, Luo, Minjie, Tereshchenko, Irina V., Frikker, Danielle M., Cui, Xiangfeng, Li, James Y., ...
A high-throughput genotyping system for scoring single nucleotide polymorphisms (SNPs) has been developed. With this system, >1000 SNPs can be analyzed in a single assay, with a sensitivity that...
Lang, Mark L, Chen, Yih-Wen, Shen, Li, Gao, Hong, Lang, Gillian A, Wade, Terri K, ...
The human IgA Fc receptor (FcalphaR, CD89) triggers several important physiological functions, including phagocytosis, NADPH oxidase activation and antigen presentation. Efforts are underway to...
Greenawalt, Danielle M., Cui, Xiangfeng, Wu, Yujun, Lin, Yong, Wang, Hui-Yun, Luo, Minjie, ...
Although the haplotype structure of the human genome has been studied in great detail, very little is known about the mechanisms underlying its formation. To investigate the role of meiotic...
Herrera, Victoria LM, Shen, Li, Lopez, Lyle V, Didishvili, Tamara, Zhang, You-Xun, Ruiz-Opazo, Nelson
Chlamydia pneumoniae (Cpn) has been associated with human coronary artery disease but causal relevance as a risk factor has not been shown. Several rabbit and mouse model studies demonstrate...
Hu, Guohong, Wang, Hui-Yun, Greenawalt, Danielle M., Azaro, Marco A., Luo, Minjie, Tereshchenko, Irina V., ...
Microarray-based analysis of single nucleotide polymorphisms (SNPs) has many applications in large-scale genetic studies. To minimize the influence of experimental variation, microarray data usually...
Shen, Li, Smith, Jennifer M, Shen, Zheng, Hussey, Stephen B, Wira, Charles R, Fanger, Michael W
Neutrophils are a normal constituent of the female reproductive tract and their numbers increase in the late secretory phase of the menstrual cycle prior to menses. Several cytokines are produced in...
Selective Promoter Recognition by Chlamydial σ28 Holoenzyme▿ †
Shen, Li, Feng, Xiaogeng, Yuan, Yuan, Luo, Xudong, Hatch, Thomas P., Hughes, Kelly T., ...
The σ transcription factor confers the promoter recognition specificity of RNA polymerase (RNAP) in eubacteria. Chlamydia trachomatis has three known sigma factors, σ66, σ54, and σ28. We...
Identification of surface-exposed components of MOMP of Chlamydia trachomatis serovar F
Wang, Yan, Berg, Eric A., Feng, Xiaogeng, Shen, Li, Smith, Temple, Costello, Catherine E., ...
The identification of surface-exposed components of the major outer membrane protein (MOMP) of Chlamydia is critical for modeling its three-dimensional structure, as well as for understanding the...
Kawana, Kei, Matsumoto, Junko, Miura, Shiho, Shen, Li, Kawana, Yukiko, Nagamatsu, Takeshi, ...
Mucosal epithelia of the human lower reproductive tract (vagina, cervix, and penile urethra) are exposed to sexually transmitted microbes, including Chlamydia trachomatis. The in vivo susceptibility...
Genetic Structures of Copy Number Variants Revealed by Genotyping Single Sperm
Luo, Minjie, Cui, Xiangfeng, Fredman, David, Brookes, Anthony J., Azaro, Marco A., Greenawalt, Danielle M., ...
An Integrated Approach to Identifying Cis-Regulatory Modules in the Human Genome
Won, Kyoung-Jae, Agarwal, Saurabh, Shen, Li, Shoemaker, Robert, Ren, Bing, Wang, Wei
In eukaryotic genomes, it is challenging to accurately determine target sites of transcription factors (TFs) by only using sequence information. Previous efforts were made to tackle this task by...
Wang, Hui-Yun, Greenawalt, Danielle, Cui, Xiangfeng, Tereshchenko, Irina V, Luo, Minjie, Yang, Qifeng, ...
Hua, Ziyu, Rao, Xiancai, Feng, Xiaogeng, Luo, Xudong, Liang, Yanmei, Shen, Li
Transcription factor σ28 in Chlamydia trachomatis (σ28Ct) plays a role in the regulation of genes that are important for late-stage morphological differentiation. In vitro mutational and genetic...
Rao, Xiancai, Deighan, Padraig, Hua, Ziyu, Hu, Xiaomei, Wang, Jin, Luo, Miao, ...
The obligate intracellular human pathogen Chlamydia trachomatis undergoes a complex developmental program involving transition between two forms: the infectious elementary body (EB), and the rapidly...
Baseline MRI Predictors of Conversion from MCI to Probable AD in the ADNI Cohort
Risacher, Shannon L, Saykin, Andrew J, West, John D, Shen, Li, Firpi, Hiram A, McDonald, Brenna C
The Alzheimer’s Disease Neuroimaging Initiative (ADNI) is a multi-center study assessing neuroimaging in diagnosis and longitudinal monitoring. Amnestic Mild Cognitive Impairment (MCI) often...
Zhou, June, Martin, Roy J., Tulley, Richard T., Raggio, Anne M., McCutcheon, Kathleen L., Shen, Li, ...
Glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) are anti-diabetes/obesity hormones secreted from the gut after meal ingestion. We have shown that dietary-resistant starch (RS) increased GLP-1...