Li Zhao

Publication List Details

Period

1994 - 2009

Number

104

Co-Authors

Localization and Mass Spectra of Fermions on Symmetric and Asymmetric Thick Branes (2009)

Liu, Yu-Xiao, Fu, Chun-E, Zhao, Li, Duan, Yi-Shi

A three-parameter (positive odd integer $s$, thickness factor $\lambda$, and asymmetry factor $a$) family of asymmetric thick brane solutions in five dimensions were constructed from a two-parameter...

Mining Compressed Repetitive Gapped Sequential Patterns Efficiently (2009)

Tong, Yongxin, Zhao, Li, Yu, Dan, Ma, Shilong, Xu, Ke

Mining frequent sequential patterns from sequence databases has been a central research topic in data mining and various efficient mining sequential patterns algorithms have been proposed and...

Optimizing Communication and Capacity in a 3D Stacked Reconfigurable Cache Hierarchy ∗ (2009)

Niti Madan, Li Zhao, Naveen Muralimanohar, Aniruddha Udipi, Rajeev Balasubramonian, Ravishankar Iyer, ...

Cache hierarchies in future many-core processors are expected to grow in size and contribute a large fraction of overall processor power and performance. In this paper, we postulate a 3D chip design...

Direct Observation of Photonic Jets and Corresponding Backscattering Enhancement at Microwave frequencies (2009)

Zhao, Li, Ong, C. K.

We experimentally verified the phenomena of photonic jets generated by plane-electromagnetic-wave-illuminated dielectric micro-cylinders with diameter comparable to the corresponding wavelength at...

Performance Evaluation and Acceleration for XML Data Parsing (2009)

Li Zhao

As XML has become a standard for data representation and exchange, XML data processing becomes more and more important for server workloads like web servers and database servers. One of the most time...

Effects of Locking and Synchronization on Future Large Scale CMP Platforms (2009)

Jaideep Moses, Ramesh Illikkal, Li Zhao, Srihari Makineni, Don Newell

Abstract – As we enter the era of large-scale Chip Multi-Processing (CMP) systems, evaluating architectures and projecting performance for commercial workloads on such systems is becoming...

A chiral three-dimensional network in poly[μ-4,4′-bipyridine-di-μ-formato-cadmium(II)] (2009)

Li Zhao, Jian-Li Lin, Wei Xu, Hong-Zhen Xie

In the title compound, [Cd(HCOO)2(C10H8N2)]n, the CdII ion, located on a position with 2.22 site symmetry, is surrounded by two 4,4′-bipyridine ligands and four formate ligands in a distorted...

Bis[4-(4-pyridyl)pyridinium] (4-carboxypyridine-2,6-dicarboxylato-κ3O2,N,O6)(pyridine-2,4,6-tricarboxylato-κ3O2,N,O6)ferrate(III) trihydrate (2009)

Li Zhao, You-Ren Dong, Hong-Zhen Xie

In the title salt, (C10H9N2)2[Fe(C8H2NO6)(C8H3NO6)]·3H2O, the FeIII atom is O,N,O′-chelated by dianionic and trianionic ligands in a slightly distorted octahedral coordination geometry....

Role of pyruvate dehydrogenase complex in traumatic brain injury and Measurement of pyruvate dehydrogenase enzyme by dipstick test (2009)

Sharma Pushpa, Benford Brandi, Li Zhao, Ling Geoffrey

Objectives: The present study was designed to investigate the role of a mitochondrial enzyme pyruvate dehydrogenase (PDH) on the severity of brain injury, and the effects of pyruvate treatment in...

Long-term myocardial functional improvement after autologous bone marrow mononuclear cells transplantation in patients with ST-segment elevation myocardial infarction: 4 years follow-up (2009)

Cao, Feng, Sun, Dongdong, Li, Chengxiang, Narsinh, Kazim, Zhao, Li, Li, Xue, ...

Aims To evaluate the safety profile and efficacy of bone marrow mononuclear cells (BMMNC) transplantation for ST-segment elevation myocardial infarction (STEMI) by assessing patients and their left...

Robust multi-clue face tracking system (2009)

Cao, Yujia, Wei, Xin, Zhao, Li, Di Federico, Riccardo

In this paper we present a multi-clue face tracking system, based on the combination of a face detector and two independent trackers. The detector, a variant of the Viola-Jones algorithm, is set to...

4-[1-(Hydroxyimino)ethyl]-N-(4-nitrobenzylidene)aniline (2009)

Li Zhao, Wen-Kui Dong, Jian-Chao Wu, Yin-Xia Sun, Li Xu

In the title compound, C15H13N3O3, the dihedral angle formed by the two benzene rings is 44.23 (2)°. The crystal structure is stabilized by aromatic π–π stacking...

Accelerating Full-System Simulation through Characterizing and Predicting Operating System Performance ∗ (2008)

Seongbeom Kim, Fang Liu, Yan Solihin, Ravi Iyer, Li Zhao, William Cohen

The ongoing trend of increasing computer hardware and software complexity has resulted in the increase in complexity and overheads of cycle-accurate processor system simulation, especially in...

Online available since 2006/Dec/15 Technology of Redevelop and Intelligent Reconfiguration Oriented to Open CNC System (2008)

Taiyong Wang, Shiguang Hu, Jian Zhao, Li Zhao, Zhiqiang Zhang

Abstract. With the increase of expanded functions, Open CNC system is getting overstuffed gradually, which leads to the decrease of flexibility and reliability. Also, it is hard for users to define...

A New Method of Fault Tolerance TCP (2008)

Li Zhao, Xu Ke, Xu Mingwei, Fu Lizheng, Wu Jianping

With the rapid development of Internet, the need of high availability of data services on Internet becomes more urgent. But as one of the most useful protocol on Internet, TCP protocol software can...

and Embedded Systems General Terms (2008)

Haiyong Xie, Li Zhao, Laxmi Bhuyan

TCP/IP protocol processing latency has been an important issue in high-speed networks. In this paper, we present an architectural study of TCP/IP protocol. We port the TCP/IP protocol stack from the...

CacheScouts: Fine-Grain Monitoring of Shared Caches in CMP Platforms (2008)

Li Zhao, Ravi Iyer, Ramesh Illikkal, Jaideep Moses, Srihari Makineni, Don Newell

As multi-core architectures flourish in the marketplace, multi-application workload scenarios (such as server consolidation) are growing rapidly. When running multiple applications simultaneously on...

1. Abstract Security Routing Analysis for Mobile Ad Hoc Networks (2008)

Dan Nguyen, Li Zhao, Pra-ornsiri Uisawang, John Platt

An ad hoc network is a collection of mobile nodes that dynamically form a temporary network. Unlike traditional wireless and mobile networks in which mobile nodes communicate with a centralized...

Exploring DRAM Cache Architectures for CMP Server Platforms (2008)

Li Zhao, Ravi Iyer, Ramesh Illikkal, Don Newell

As dual-core and quad-core processors arrive in the marketplace, the momentum behind CMP architectures continues to grow strong. As more and more cores/threads are placed on-die, the pressure on the...

IMPROVE PACKET THROUGHPUT. (2008)

Li Zhao, Yan Luo, Laxmi N. Bhuyan, Ravi Iyer

With the explosive growth in Internet traffic, requests have been overloading Web servers. Many ISPs and search engines employ a server cluster to build a cost-effective, scalable, and reliable...

Self-Dual Vortices in the Fractional Quantum Hall System (2007)

Zhang, Xin-Hui, Duan, Yi-Shi, Liu, Yu-Xiao, Zhao, Li

Based on the $\phi$-mapping theory, we obtain an exact Bogomol'nyi self-dual equation with a topological term, which is ignored in traditional self-dual equation, in the fractional quantum Hall...

On Illumination Effects in PCA-Based Vision Systems (2007)

Li Zhao, Yee-hong Yang

In this paper, a theoretical method to analyse the illumination effects in principal component analysis (PCA) based vision systems is presented. In the first part, an analytical closed-formed formula...

Header for SPIE use Video shot grouping using best-first model merging (2007)

Li Zhao, Shi-qiang Yang, H. J. Zhang

For more efficiently organizing, browsing, and retrieving digital video, it is important to extract video structure information at both scene and shot levels. This paper presents an effective...

Architectural Analysis and Instruction-Set Optimization for Design of Network Protocol Processors (2007)

Haiyong Xie Li, Li Zhao, Laxmi Bhuyan

TCP/IP protocol processing latency has been an important issue in high-speed networks. In this paper, we present an architectural study of TCP/IP protocol. We port the TCP/IP protocol stack from the...

Fermions in gravity and gauge backgrounds on a brane world (2007)

Zhao, Li, Liu, Yu-Xiao, Duan, Yi-Shi

We solve the fermionic zero modes in gravity and gauge backgrounds on a brane involving a warped geometry, and study the localization of spin 1/2 fermionic field on the brane world. The result is...

Fermions in Self-dual Vortex Background on a String-like Defect (2007)

Liu, Yu-Xiao, Zhao, Li, Zhang, Xin-Hui, Duan, Yi-Shi

By using the self-dual vortex background on extra two-dimensional Riemann surfaces in 5+1 dimensions, the localization mechanism of bulk fermions on a string-like defect with the exponentially...

Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells (2007)

Yu, Jun, Guo, Qing-Long, You, Qi-Dong, Zhao, Li, Gu, Hong-Yan, Yang, Yong, ...

Molecular mechanisms of cell-cycle arrest caused by gambogic acid (GA), a natural product isolated from the gamboge resin of Garcinia hanburryi tree, have been investigated using BGC-823 human...

Knotted Solitons in a Charged Two-Condensate Bose System (2007)

Duan, Yi-Shi, Zhang, Xin-Hui, Liu, Yu-Xiao, Zhao, Li

By making use of the decomposition of U(1) gauge potential theory and the \phi mapping method, we propose that a charged two-condensate Bose system possesses vortex lines and two classes of knotted...

Topological Vortex Lines in Two-Gap Superconductor (2007)

Duan, Yi-Shi, Zhang, Xin-Hui, Zhao, Li

Based on the U(1) gauge potential decomposition theory and the $\phi$-mapping method, we study the vortex lines in two-gap superconductor and obtain the condition, under which the vortices can carry...

Topological aspect of black hole with Skyrme hair (2007)

Duan, Yi-Shi, Zhang, Xin-Hui, Zhao, Li

Based on the $\phi$-mapping topological current theory, we show that the presence of the black hole leaves fractional baryon charge outside the horizon in the Einstein-Skyrme theory. A topological...

Novel Topological Invariant in the U(1) Gauge Field Theory (2007)

Duan, Yi-Shi, Zhang, Xin-Hui, Zhao, Li

Based on the decomposition of U(1) gauge potential theory and the $\phi$-mapping topological current theory, the three-dimensional knot invariant and a four-dimensional new topological invariant are...

Fermion Absorption Cross Section and Topology of Spherically Symmetric Black Holes (2007)

Liu, Yu-Xiao, Zhao, Li, Cao, Zhen-Bin, Duan, Yi-Shi

In 1997, Liberati and Pollifrone in Phys. Rev. D56 (1997) 6458 (hep-th/9708014) achieved a new formulation of the Bekenstein-Hawking formula, where the entropy and the Euler characteristic are...

Localization of Fermions on a String-like Defect (2007)

Liu, Yu-Xiao, Zhao, Li, Duan, Yi-Shi

We study localization of bulk fermions on a string-like defect with the exponentially decreasing warp factor in six dimensions with inclusion of U(1) gauge background from the viewpoint of field...

Hardware Support for Accelerating Data Movement in Server Platform (2007)

Li Zhao, Laxmi N. Bhuyan, Ravi Iyer, Srihari Makineni, Donald Newell

Abstract—Data movement (memory copies) is a very common operation during network processing and application execution on servers. The performance of this operation is rather poor on today’s...

QoS Policy and Architecture for Cache/Memory in CMP Platforms (2007)

Ravi Iyer, Li Zhao, Fei Guo, Ramesh Illikkal, Srihari Makineni, Don Newell, ...

As we enter the era of CMP platforms with multiple threads/cores on the die, the diversity of the simultaneous workloads running on them is expected to increase. The rapid deployment of...

Performance, Area and Bandwidth Implications on Large-Scale CMP Cache Design (2007)

Li Zhao, Ravi Iyer, Srihari Makineni, Jaideep Moses, Ramesh Illikkal, Donald Newell

Large-scale CMP (LCMP) platforms that consist of 10s of cores for throughput computing will soon become reality. The performance and scalability of these architectures is highly dependent on the...

Hardware Support for Accelerating Data Movement in Server Platform (2007)

Li Zhao, Laxmi N. Bhuyan, Ravi Iyer, Srihari Makineni, Donald Newell

Abstract—Data movement (memory copies) is a very common operation during network processing and application execution on servers. The performance of this operation is rather poor on today’s...

The Chinese Quality Of Life Instrument: Development Of A New Health-Related Quality Of Life Instrument Using Factor Analysis And Structural Equation Modeling (2006)

Zhao, Li, Chan, Kelvin C., Leung, Kwok-fai, Liu, Feng-bin, Lang, Jian-ying, Fang, Ji-qian

A new Chinese Quality of Life Instrument (ChQOL) based on the principles of diagnosis and practice in Chinese medicine has been developed. This paper describes the development of the ChQOL instrument...

Full 3D tomography for the crustal structure (2006)

Po Chen, Li Zhao, Thomas H. Jordan

Abstract We apply full 3D tomography (F3DT) to a regional dataset in the Los Angeles area. In F3DT, the starting model as well as the model perturbation is three-dimensional and the sensitivity...

Full 3D tomography: a comparison between the scattering-integral and adjoint-wavefield methods (2006)

Po Chen, Thomas H. Jordan, Li Zhao

This paper analyzes the computational issues of full 3D tomography, in which the starting model as well as the model perturbation is three-dimensional and the sensitivity (Fréchet) kernels are...

Managing Large-Scale Workflow Execution from Resource Provisioning to Provenance Tracking: The CyberShake Example (2006)

Ewa Deelman, Scott Callaghan, Edward Field, Hunter Francoeur, Robert Graves, Vipin Gupta, ...

This paper discusses the process of building an environment where large-scale, complex, scientific analysis can be scheduled onto a heterogeneous collection of computational and storage resources....

Gambogic acid induced G2/M phase cell cycle arrest via disturbing CDK7 mediated phosphorylation of CDC2/P34 in human gastric carcinoma BGC-823 cells (2006)

Jun, Yu, Guo, Qing-Long, You, Qi-Dong, Zhao, Li, Gu, Hong-Yan, Yang, Yong, ...

Molecular mechanisms of cell cycle arrest caused by gambogic acid (GA), a natural product isolated from the gamboge resin of Garcinia hanburryi tree, has been investigated using BGC-823 human gastric...

The U(1) Topological Gauge Field Theory for Topological Defects in Liquid Crystals (2005)

Duan, Yi-shi, Zhao, Li, Zhang, Xin-hui, Si, Tie-yan

A novel U(1) topological gauge field theory for topological defects in liquid crystals is constructed by considering the U(1) gauge field is invariant under the director inversion. Via the U(1) gauge...

The Chinese Quality Of Life Instrument: Development Of A New Health-Related Quality Of Life Instrument Using Factor Analysis And Structural Equation Modeling (2005)

Zhao, Li, Chan, Kelvin, Leung, Kwok-fai, Liu, Feng-bin, Lang, Jian-ying, Fang, Ji-qian

A new Chinese Quality of Life Instrument (ChQOL) based on the principles of diagnosis and practice in Chinese medicine has been developed. This paper describes the development of the ChQOL instrument...

The Chinese Quality Of Life Instrument: Development Of A New Health-Related Quality Of Life Instrument Using Factor Analysis And Structural Equation Modeling (2005)

Zhao, Li, Chan, Kelvin, Leung, Kwok-fai, Liu, Feng-bin, Lang, Jian-ying, Fang, Ji-qian

A new Chinese Quality of Life Instrument (ChQOL) based on the principles of diagnosis and practice in Chinese medicine has been developed. This paper describes the development of the ChQOL instrument...

The Chinese Quality Of Life Instrument: Development Of A New Health-Related Quality Of Life Instrument Using Factor Analysis And Structural Equation Modeling (2005)

Zhao, Li, Chan, Kelvin, Leung, Kwok-fai, Liu, Feng-bin, Lang, Jian-ying, Fang, Ji-qian

A new Chinese Quality of Life Instrument (ChQOL) based on the principles of diagnosis and practice in Chinese medicine has been developed. This paper describes the development of the ChQOL instrument...

The Chinese Quality Of Life Instrument: Development Of A New Health-Related Quality Of Life Instrument Using Factor Analysis And Structural Equation Modeling (2005)

Zhao, Li, Chan, Kelvin, Leung, Kwok-fai, Liu, Feng-bin, Lang, Jian-ying, Fang, Ji-qian

A new Chinese Quality of Life Instrument (ChQOL) based on the principles of diagnosis and practice in Chinese medicine has been developed. This paper describes the development of the ChQOL instrument...

Development and validation of the Chinese Quality of Life Instrument (2005)

Leung, Kwok-fai, Liu, Feng-bin, Zhao, Li, Fang, Ji-qian, Chan, Kelvin, Lin, Li-zhu

Abstract Background This paper describes the development of the Chinese Quality of Life Instrument (ChQOL) which is a self-report health status instrument. Chinese Medicine relies very much on asking...

Development and validation of the Chinese Quality of Life Instrument. (2005)

Leung, Kwok-fai, Liu, Feng-bin, Zhao, Li, Fang, Ji-qian, Chan, Kelvin, Lin, Li-zhu

BACKGROUND: This paper describes the development of the Chinese Quality of Life Instrument (ChQOL) which is a self-report health status instrument. Chinese Medicine relies very much on asking...

Development and validation of the Chinese Quality of Life Instrument. (2005)

Leung, Kwok-fai, Liu, Feng-bin, Zhao, Li, Fang, Ji-qian, Chan, Kelvin C., Lin, Li-zhu

BACKGROUND: This paper describes the development of the Chinese Quality of Life Instrument (ChQOL) which is a self-report health status instrument. Chinese Medicine relies very much on asking...

Building a bridge for integrating Chinese medicine into conventional healthcare: observations drawn from the development of the Chinese quality of life instrument. (2005)

Zhao, Li, Chan, Kelvin C.

This paper describes the methods and theories of patient-reported outcomes, in particular to the health-related quality of life recently applied in Chinese medicine research. It begins with an...

SpliceNP: A TCP Splicer using Network Processors (2005)

Li Zhao, Yan Luo, Laxmi Bhuyan

TCP Splicing can be used in content-aware switches to tremendously reduce overall request latency. In order to reduce the processing latency further, we propose to offload the protocol processing...

Hardware support for bulk data movement in server platforms (2005)

Li Zhao, Ravi Iyer, Srihari Makineni, Laxmi Bhuyan, Don Newell

Bulk data movement occurs commonly in server workloads and their performance is rather poor on today’s microprocessors. We propose the use of small dedicated copy engines, and present a detailed...

A peer-to-peer network for live media streaming using a push-pull approach (2005)

Meng Zhang, Jian-guang Luo, Li Zhao, Shi-qiang Yang

In this paper, we present an unstructured peer-to-peer network called GridMedia for live media streaming employing a push-pull approach. Each node in GridMedia randomly selects its neighbors in the...

Design and implementation of a content-aware switch using a network processor (2005)

Li Zhao, Yan Luo, Laxmi Bhuyan

Cluster based server architectures have been widely used as a solution to overloading in web servers because of their cost effectiveness, scalability and reliability. A content aware switch can be...

Design and implementation of a content-aware switch using a network processor (2005)

Li Zhao, Yan Luo, Laxmi Bhuyan

Cluster based server architectures have been widely used as a solution to overloading in web servers because of their cost effectiveness, scalability and reliability. A content aware switch can be...

Architectural analysis and acceleration for server network processing / (2005)

Zhao, Li.

Thesis (Ph. D.)--University of California, Riverside, 2005.

Efficient caching techniques for server network acceleration (2004)

Li Zhao, Srihari Makineni, Ramesh Illikkal, Ravi Iyer, Laxmi Bhuyan

Abstract – A majority of server applications such as web server, database, E-mail, storage, etc. process a lot of network data, making them very network I/O intensive. TCP/IP is the most commonly...

TCP/IP cache characterization in commercial server workloads (2004)

Li Zhao, Ramesh Illikkal, Srihari Makineni, Laxmi Bhuyan

Abstract – Internet server applications (such as web servers, ecommerce front-ends, etc) spend a significant portion of time processing network data. These applications use TCP/IP as the...

Musculoskeletal complaints and psychosocial risk factors among Chinese hospital nurses (2004)

Smith, Derek R., Wei, Ning, Zhao, Li, Wang, Rui-Sheng

Background Musculoskeletal complaints represent a common occupational problem for health care workers throughout the world. Despite their sizeable numbers, however, few epidemiological studies have...

Mechanistic Studies on Phosphatidylinositol-specific Phospholitase C (2003)

Zhao, Li

This work combines the use of thio effects and site-directed mutagenesis (SDM) to characterize the catalytic mechanisms of phosphatidylinositol-specific phospholipase Cs (PI-PLCs). Eukaryotic PI-PLCs...

Mechanistic Studies on Phosphatidylinositol-specific Phospholitase C (2003)

Zhao, Li

This work combines the use of thio effects and site-directed mutagenesis (SDM) to characterize the catalytic mechanisms of phosphatidylinositol-specific phospholipase Cs (PI-PLCs). Eukaryotic PI-PLCs...

MAC protocols for ultra wideband (UWB) wireless networks: Impact of channel acquisition time (2002)

Jin Ding, Li Zhao, Sirisha R. Medidi, Krishna M. Sivalingam

The upcoming Ultra-wide-band (UWB) radio technology holds great promise for revolutionizing wireless communications. UWB radios transmit using precise, very short (e.g. picosecond) impulses spread...

A work structure based approach to collaborative engineering design / (2002)

Zhao, Li.

Thesis (Ph. D.)--University of Southern California, 2002.

Faster Algorithm of String Comparison (2001)

Yang, Qi Xiao, Yuan, Sung Sam, Chun, Lu, Zhao, Li, Peng, Sun

In many applications, it is necessary to determine the string similarity. Edit distance[WF74] approach is a classic method to determine Field Similarity. A well known dynamic programming algorithm...

Perspectives on the Role of Government Risk-Bearing within the Financial Sector (2001)

Li Zhao, S. Z. Li, S. Q. Yang, H. J. Zhang

The shot based classification and retrieval is very important for video database organization and access. In this paper we present a new approach ‘Nearest Feature Line – NFL ’ used in shot...

Explorations of human visual coding / (2000)

Zhao, Li.

Thesis (Ph. D., Psychology)--University of California, Irvine, 2000.

Key-frame extraction and shot retrieval using nearest feature line (2000)

Li Zhao, Stanz. Li, Shi-qiang Yang, H. J. Zhang

Query by key frame or video example is a convenient and often effective way to search in video database. This paper proposes a new approach to support such searches. The main contribution of the...

Thermodynamics of beryllium corrosion /--by Li Zhao. (1999)

Zhao, Li.

Thesis (M.S. in Engin.)--University of Texas at Austin, 1999.

Mosaic Image Method: a Local and Global Method (1999)

Li Zhao, Yee-hong Yang

In this paper, a new method to compute eigenimages in principal component analysis (PCA) based vision systems is presented. It is called Mosaic Image Method. In this method, the object is represented...

The influence of boundary-conditions on resonant frquencies of cavities in 3-D FDTD algorithm using nonorthogonal coordinates. (1994)

Zhao, Li, Tong, Lin S., Carter, Richard G.

The 3-dimensional finite-difference time-domain method in non-orthogonal co-ordinates (non-standard FDTD) is used to calculate the frequencies of resonators. The numerical boundary conditions of the...

Two crises of decision in Jane Eyre /--by Zhao Li. (1994)

Zhao, Li.

Thesis (M.A.)--Western Carolina University, 1994.

Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors

Dace, Alexandra, Zhao, Li, Park, Kyung Soo, Furuno, T., Takamura, N., Nakanishi, M., ...

The thyroid hormone 3,3′,5-triiodo-l-thyronine (T3) is essential for growth, differentiation, and development. Its biological activities are mediated by T3 nuclear receptors (TRs). At present, how...

P15 and P3, the Tail Completion Proteins of Bacteriophage T4, Both Form Hexameric Rings

Zhao, Li, Kanamaru, Shuji, Chaidirek, Chatree'chalerm, Arisaka, Fumio

Two proteins, gp15 and gp3 (gp for gene product), are required to complete the assembly of the T4 tail. gp15 forms the connector which enables the tail to bind to the head, whereas gp3 is involved in...

Members of the Large Maf Transcription Family Regulate Insulin Gene Transcription in Islet β Cells

Matsuoka, Taka-aki, Zhao, Li, Artner, Isabella, Jarrett, Harry W., Friedman, David, Means, Anna, ...

The C1/RIPE3b1 (−118/−107 bp) binding factor regulates pancreatic-β-cell-specific and glucose-regulated transcription of the insulin gene. In the present study, the C1/RIPE3b1 activator from...

An Unliganded Thyroid Hormone β Receptor Activates the Cyclin D1/Cyclin-Dependent Kinase/Retinoblastoma/E2F Pathway and Induces Pituitary Tumorigenesis

Furumoto, Hiroko, Ying, Hao, Chandramouli, G. V. R., Zhao, Li, Walker, Robert L., Meltzer, Paul S., ...

Thyroid-stimulating hormone (TSH)-secreting tumors (TSH-omas) are pituitary tumors that constitutively secrete TSH. The molecular genetics underlying this abnormality are not known. We discovered...

Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone β receptor inhibits mitotic progression

Ying, Hao, Furuya, Fumihiko, Zhao, Li, Araki, Osamu, West, Brian L., Hanover, John A., ...

Overexpression of pituitary tumor–transforming 1 (PTTG1) is associated with thyroid cancer. We found elevated PTTG1 levels in the thyroid tumors of a mouse model of follicular thyroid carcinoma...

Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors

Dace, Alexandra, Zhao, Li, Park, Kyung Soo, Furuno, T., Takamura, N., Nakanishi, M., ...

The thyroid hormone 3,3′,5-triiodo-l-thyronine (T3) is essential for growth, differentiation, and development. Its biological activities are mediated by T3 nuclear receptors (TRs). At present, how...

P15 and P3, the Tail Completion Proteins of Bacteriophage T4, Both Form Hexameric Rings

Zhao, Li, Kanamaru, Shuji, Chaidirek, Chatree'chalerm, Arisaka, Fumio

Two proteins, gp15 and gp3 (gp for gene product), are required to complete the assembly of the T4 tail. gp15 forms the connector which enables the tail to bind to the head, whereas gp3 is involved in...

Members of the Large Maf Transcription Family Regulate Insulin Gene Transcription in Islet β Cells

Matsuoka, Taka-aki, Zhao, Li, Artner, Isabella, Jarrett, Harry W., Friedman, David, Means, Anna, ...

The C1/RIPE3b1 (−118/−107 bp) binding factor regulates pancreatic-β-cell-specific and glucose-regulated transcription of the insulin gene. In the present study, the C1/RIPE3b1 activator from...

An Unliganded Thyroid Hormone β Receptor Activates the Cyclin D1/Cyclin-Dependent Kinase/Retinoblastoma/E2F Pathway and Induces Pituitary Tumorigenesis

Furumoto, Hiroko, Ying, Hao, Chandramouli, G. V. R., Zhao, Li, Walker, Robert L., Meltzer, Paul S., ...

Thyroid-stimulating hormone (TSH)-secreting tumors (TSH-omas) are pituitary tumors that constitutively secrete TSH. The molecular genetics underlying this abnormality are not known. We discovered...

Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone β receptor inhibits mitotic progression

Ying, Hao, Furuya, Fumihiko, Zhao, Li, Araki, Osamu, West, Brian L., Hanover, John A., ...

Overexpression of pituitary tumor–transforming 1 (PTTG1) is associated with thyroid cancer. We found elevated PTTG1 levels in the thyroid tumors of a mouse model of follicular thyroid carcinoma...

Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase

Forouhar, Farhad, Anderson, J. L. Ross, Mowat, Christopher G., Vorobiev, Sergey M., Hussain, Arif, Abashidze, Mariam, ...

Tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) constitute an important, yet relatively poorly understood, family of heme-containing enzymes. Here, we report extensive...

Nuclear Receptor Corepressor Is a Novel Regulator of Phosphatidylinositol 3-Kinase Signaling▿

Furuya, Fumihiko, Guigon, Celine J., Zhao, Li, Lu, Changxue, Hanover, John A., Cheng, Sheue-yann

The nuclear receptor corepressor (NCoR) regulates the activities of DNA-binding transcription factors. Recent observations of its distribution in the extranuclear compartment raised the possibility...

Helical domain and kinase domain mutations in p110α of phosphatidylinositol 3-kinase induce gain of function by different mechanisms

Zhao, Li, Vogt, Peter K.

The phosphatidylinositol 3-kinase (PI3K) signaling pathway is up-regulated in cancer. PIK3CA, the gene coding for the catalytic subunit p110α of PI3K, is mutated in ≈30% of tumors of the prostate,...

Regulation of β-Catenin by a Novel Nongenomic Action of Thyroid Hormone β Receptor▿

Guigon, Celine J., Zhao, Li, Lu, Changxue, Willingham, Mark C., Cheng, Sheue-yann

We previously created a knock-in mutant mouse harboring a dominantly negative mutant thyroid hormone receptor β (TRβPV/PV mouse) that spontaneously develops a follicular thyroid carcinoma similar...

Structural basis for suppression of a host antiviral response by influenza A virus

Das, Kalyan, Ma, Li-Chung, Xiao, Rong, Radvansky, Brian, Aramini, James, Zhao, Li, ...

Influenza A viruses are responsible for seasonal epidemics and high mortality pandemics. A major function of the viral NS1A protein, a virulence factor, is the inhibition of the production of IFN-β...

Extensive HIV-1 Intra-Host Recombination Is Common in Tissues with Abnormal Histopathology

Lamers, Susanna L., Salemi, Marco, Galligan, Derek C., De Oliveira, Tulio, Fogel, Gary B., Granier, Sara C., ...

There is evidence that immune-activated macrophages infected with the Human Immunodeficiency Virus (HIV) are associated with tissue damage and serve as a long-lived viral reservoir during therapy. In...

A Start for Mild Liberalization? Building Civil Society through Co-operative Dynamics in China

Li Zhao

This paper aims to understand the society-state relationship in China, by exploring this dynamics with other types of organizations, i.e. civil society organizations with economic objectives. The...