Gao, Lian-Yong, Abu Kwaik, Yousef
The hallmark of Legionnaires’ disease is intracellular replication of Legionella pneumophila within cells in the alveolar spaces. Cytopathogenicity of this bacterium to the host cell has been well...
Activation of Caspase 3 during Legionella pneumophila-Induced Apoptosis
Gao, Lian-Yong, Abu Kwaik, Yousef
The hallmark of Legionnaires’ disease is replication of Legionella pneumophila within cells in the alveolar spaces. The mechanisms by which L. pneumophila replicates intracellularly and kills the...
Alli, O. A. Terry, Gao, Lian-Yong, Pedersen, Lisa L., Zink, Steven, Radulic, Marina, Doric, Miljenko, ...
Legionella pneumophila does not induce apoptosis in the protozoan host, but induces pore formation-mediated cytolysis after termination of intracellular replication (L.-Y. Gao and Y. Abu Kwaik,...
Invasion of Protozoa by Legionella pneumophila and Its Role in Bacterial Ecology and Pathogenesis
Abu Kwaik, Yousef, Gao, Lian-Yong, Stone, Barbara J., Venkataraman, Chandrasekar, Harb, Omar S.
Gao, Lian-Yong, Harb, Omar S., Kwaik, Yousef Abu
We have recently shown that many mutants of Legionella pneumophila exhibit similar defective phenotypes within both U937 human-derived macrophages and the protozoan host Acanthamoeba (L.-Y. Gao, O....
Harb, Omar S., Venkataraman, Chandrasekar, Haack, Bradley J., Gao, Lian-Yong, Kwaik, Yousef Abu
Invasion and intracellular replication of Legionella pneumophila within protozoa in the environment plays a major role in the transmission of Legionnaires’ disease. Intracellular replication of L....
Gao, Lian-Yong, Groger, Richard, Cox, Jeffery S., Beverley, Stephen M., Lawson, Elise H., Brown, Eric J.
Pathogenic mycobacteria survive and replicate within host macrophages, but the molecular mechanisms involved in this necessary step in the pathogenesis of infection are not completely understood....
Gao, Lian-Yong, Pak, Melissa, Kish, Rabab, Kajihara, Kimberly, Brown, Eric J.
The ability to invade and grow in macrophages is necessary for Mycobacterium tuberculosis to cause disease. We have found a Mycobacterium marinum locus of two genes that is required for both invasion...
Gao, Lian-Yong, Abu Kwaik, Yousef
The hallmark of Legionnaires’ disease is intracellular replication of Legionella pneumophila within cells in the alveolar spaces. Cytopathogenicity of this bacterium to the host cell has been well...
Activation of Caspase 3 during Legionella pneumophila-Induced Apoptosis
Gao, Lian-Yong, Abu Kwaik, Yousef
The hallmark of Legionnaires’ disease is replication of Legionella pneumophila within cells in the alveolar spaces. The mechanisms by which L. pneumophila replicates intracellularly and kills the...
Alli, O. A. Terry, Gao, Lian-Yong, Pedersen, Lisa L., Zink, Steven, Radulic, Marina, Doric, Miljenko, ...
Legionella pneumophila does not induce apoptosis in the protozoan host, but induces pore formation-mediated cytolysis after termination of intracellular replication (L.-Y. Gao and Y. Abu Kwaik,...
Invasion of Protozoa by Legionella pneumophila and Its Role in Bacterial Ecology and Pathogenesis
Abu Kwaik, Yousef, Gao, Lian-Yong, Stone, Barbara J., Venkataraman, Chandrasekar, Harb, Omar S.
Gao, Lian-Yong, Harb, Omar S., Kwaik, Yousef Abu
We have recently shown that many mutants of Legionella pneumophila exhibit similar defective phenotypes within both U937 human-derived macrophages and the protozoan host Acanthamoeba (L.-Y. Gao, O....
Harb, Omar S., Venkataraman, Chandrasekar, Haack, Bradley J., Gao, Lian-Yong, Kwaik, Yousef Abu
Invasion and intracellular replication of Legionella pneumophila within protozoa in the environment plays a major role in the transmission of Legionnaires’ disease. Intracellular replication of L....
Gao, Lian-Yong, Groger, Richard, Cox, Jeffery S., Beverley, Stephen M., Lawson, Elise H., Brown, Eric J.
Pathogenic mycobacteria survive and replicate within host macrophages, but the molecular mechanisms involved in this necessary step in the pathogenesis of infection are not completely understood....
Gao, Lian-Yong, Pak, Melissa, Kish, Rabab, Kajihara, Kimberly, Brown, Eric J.
The ability to invade and grow in macrophages is necessary for Mycobacterium tuberculosis to cause disease. We have found a Mycobacterium marinum locus of two genes that is required for both invasion...
Marbach-Ad, Gili, Briken, Volker, Frauwirth, Kenneth, Gao, Lian-Yong, Hutcheson, Steven W., Joseph, Sam W., ...
As research faculty with expertise in the area of host–pathogen interactions (HPI), we used a research group model to effect our professional development as scientific educators. We have...
Mycobacterium marinum Escapes from Phagosomes and Is Propelled by Actin-based Motility
Stamm, Luisa M., Morisaki, J. Hiroshi, Gao, Lian-Yong, Jeng, Robert L., McDonald, Kent L., Roth, Robyn, ...
Mycobacteria are responsible for a number of human and animal diseases and are classical intracellular pathogens, living inside macrophages rather than as free-living organisms during infection....
Venkataraman, Chandrasekar, Gao, Lian-Yong, Bondada, Subbarao, Kwaik, Yousef Abu
The Legionnaires' disease bacterium, Legionella pneumophila, is a facultative intracellular pathogen that invades and replicates within two evolutionarily distant hosts, free living protozoa and...