Sakata, Toshio, Chen, Lin, Sumi, Toshio, Miyazaki, Mitsuhiro
Quantum communication is concerned with the complexity of entanglement of a state and statistical data analysis is concerned with the complexity of a model. A common key word for both is "rank". In...
Geometric measure of entanglement for pure multipartite states (2009)
Chen, Lin, Xu, Aimin, Zhu, Huangjun
We compute the geometric measure of entanglement for extensive pure multipartite states. First, we analytically compute the geometric measure for symmetric three-qubit states. Next, we provide an...
Bouchard-Klemm-Marino-Pasquetti Conjecture for $\mathbb{C}^3$ (2009)
In this paper, we give a proof of the Bouchard-Klemm-Marino-Pasquetti conjecture for a framed vertex, by using the symmetrized Cut-Join Equation developed in a previous paper.
Yao, Hui-Peng, Xiang, Xing-Wei, Chen, Lin
The midgut is the digestive apparatus of the silkworm and its proteome was studied by using nano-LC (liquid chromatography) electrospray ionization MS/MS (tandem MS). MS data were analysed by using...
Topology Correction for Brain Atlas Segmentation using a Multiscale Algorithm (2009)
Abstract. In medicine and neuroscience, the reconstruction of anatomical structures from brain MRI images is an important goal, especially for regions in the human cerebral cortex. Topological...
Sudden death of distillability in qutrit-qutrit systems (2009)
Song, Wei, Chen, Lin, Zhu, Shi-Liang
We introduce the concept of distillability sudden death, i.e., free entangled states can evolve into non-distillable (bound entangled or separable) states in finite time under local noise. We...
Expertise analysis in a question answer portal for author ranking (2009)
An online question answering (QA) portal provides users a way to socialize and help each other to solve problems. The majority of the online question answer systems use user-feedback to rank users’...
A burst of segmental duplications in the genome of the African great ape ancestor (2009)
Marqués-Bonet, Tomàs, Kidd, Jeffrey M., Ventura, Mario, Graves, Tina A., Cheng, Ze, Hillier, LaDeana W., ...
5 pages, 4 figures.-- Supplementary information (3 files) available at: http://www.nature.com/nature/journal/v457/n7231/suppinfo/nature07744.html
Wireless Mesh Networks (WMNs) Wireless Mesh Networks (WMNs) (2009)
Wireless Mesh Networks (WMNs) have been expected to be the ultimate solution for the next decade wireless networking. The attractions of WMNs include easy set-up on the fly, off-the-shelf cost,...
The potassium channel Kv4.2 is expressed in subtypes of retinal ganglion cells (2009)
Fast transient potassium currents (IA ) contribute to neuronal plasticity by regulating action potential generation and signal processing in dendrites. Kv4.2 channels generate transient potassium...
Expertise analysis in a question answer portal for author ranking (2009)
An online question answering (QA) portal provides users a way to socialize and help each other to solve problems. The majority of the online question answer systems use user-feedback to rank users’...
Auxiliary Principle for Generalized Strongly Nonlinear Mixed Variational-Like Inequalities (2009)
Zeqing Liu, Lin Chen, Jeong Sheok Ume, Shin Min Kang
We introduce and study a class of generalized strongly nonlinear mixed variational-like inequalities, which includes several classes of variational inequalities and variational-like inequalities as...
Expertise analysis in a question answer portal for author ranking (2009)
An online question answering (QA) portal provides users a way to socialize and help each other to solve problems. The majority of the online question answer systems use user-feedback to rank users’...
On Multipath Routing in Multihop Wireless Networks: Security, Performance, and Their Tradeoff (2009)
Routing amid malicious attackers in multihop wireless networks with unreliable links is a challenging task. In this paper, we address the fundamental problem of how to choose secure and reliable...
Girirajan, Santhosh, Chen, Lin, Graves, Tina, Marques-Bonet, Tomas, Ventura, Mario, Fronick, Catrina, ...
The gibbon genome exhibits extensive karyotypic diversity with an increased rate of chromosomal rearrangements during evolution. In an effort to understand the mechanistic origin and implications of...
Human RIF1 encodes an anti-apoptotic factor required for DNA repair (2009)
Wang, Haibo, Zhao, Ailian, Chen, Lin, Zhong, Xueyan, Liao, Ji, Gao, Min, ...
Human Rap1-interacting protein 1 (RIF1) contributes to the ataxia telangiectasia, mutated-mediated DNA damage response against the dexterous effect of DNA lesions and plays a critical role in the...
Auxiliary Principle for Generalized Strongly Nonlinear Mixed Variational-Like Inequalities (2009)
Zeqing Liu, Lin Chen, Jeong Sheok Ume, Shin Min Kang
We introduce and study a class of generalized strongly nonlinear mixed variational-like inequalities, which includes several classes of variational inequalities and variational-like inequalities as...
On Multipath Routing in Multihop Wireless Networks: Security, Performance, and Their Tradeoff (2009)
Routing amid malicious attackers in multihop wireless networks with unreliable links is a challenging task. In this paper, we address the fundamental problem of how to choose secure and reliable...
Expertise analysis in a question answer portal for author ranking (2009)
An online question answering (QA) portal provides users a way to socialize and help each other to solve problems. The majority of the online question answer systems use user-feedback to rank users’...
Chen, Lin, Zhang, Shuiming, Illa, Eudald, Song, Lijuan, Wu, Shandong, Howad, Werner, ...
Abstract Background Fruits from several species of the Rosaceae family are reported to cause allergic reactions in certain populations. The allergens identified belong to mainly four protein...
Lukas, Thomas J, Miao, Haixi, Chen, Lin, Riordan, Sean M, Li, Wenjun, Crabb, Andrea M, ...
Abstract Background Epidemiological and genetic studies indicate that ethnic/genetic background plays an important role in susceptibility to primary open angle glaucoma (POAG). POAG is more prevalent...
Framed Deformation of Galois Representation (2008)
We studied framed deformations of two dimensional Galois representation of which the residue representation restrict to decomposition groups are scalars, and established a modular lifting theorem for...
Lin Chen, Qian Zhang, Minglu Li
Due to the low cost, ease of deployment, increased coverage, and enhanced capacity, multi-radio mesh networks that utilize inexpensive and readily available IEEE 802.11 wireless interfaces are touted...
Rank three bipartite entangled states are distillable (2008)
We prove that the bipartite entangled state of rank three is distillable. So there is no rank three bipartite bound entangled state. By using this fact, We present some families of rank four states...
Technical Report No. 97-412 On the Power of Some PRAM Models (2008)
The focus here is the power of some underexplored CRCW PRAMs, which are strictly more powerful than exclusive write PRAM but strictly less powerful than BSR. We show that some problems can be solved...
1,2-Bis[amino(pyrimidin-2-yl)methylene]hydrazine dihydrate (2008)
Shuo Shi, Tian-ming Yao, Xiao-ting Geng, Lin Chen, Liang-nian Ji
The centrosymmetric organic molecule in the title compound, C10H10N8·2H2O, is essentially flat and has a trans configuration. The molecules are linked by intermolecular O—H...N,...
2-Acetamido-3-(4-hydroxy-3-methoxyphenyl)acrylic acid (2008)
Xiao-Bing Lan, Ye-Fei Nan, Lin Chen, Shi-Xiang Wang, Xiao-Hui Zheng
In the title compound, C12H13NO5, the azlactone of vanillin, the acrylic acid side chain has a trans extended conformation. There are intermolecular N—H...O and O—H...O hydrogen bonds in...
Lu Qing, Jiang Bo, Lin Chen, Shan Tao
Abstract Background To evaluate the relationship between Aberrant Crypt Foci (ACF) and tumorigenesis, we observed the sequential development from ACF to tumor in the colon of azoxymethane-exposed...
Genome analysis of the platypus reveals unique signatures of evolution (2008)
Warren, Wesley C., Hillier, LaDeana W., Marshall Graves, Jennifer A., Birney, Ewan, Ponting, Chris P., Grützner, Frank, ...
We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a...
Kirsch, Stefan, Münch, Claudia, Jiang, Zhaoshi, Cheng, Ze, Chen, Lin, Batz, Christiane, ...
Human chromosomal regions enriched in segmental duplications are subject to extensive genomic reorganization. Such regions are particularly informative for illuminating the evolutionary history of a...
Les réseaux sans fil ont connu un succès sans précédent ces deux dernières décennies grâce à la prolifération des dispositifs sans fil peu coûteux et largement disponibles. Avec une telle...
Les réseaux sans fil ont connu un succès sans précédent ces deux dernières décennies grâce à la prolifération des dispositifs sans fil peu coûteux et largement disponibles. Avec une telle...
Les réseaux sans fil ont connu un succès sans précédent ces deux dernières décennies grâce à la prolifération des dispositifs sans fil peu coûteux et largement disponibles. Avec une telle...
Gabriele Lohmann, Karsten Muller, Volker Bosch, Heiko Mentzel, Sven Hessler, Lin Chen, ...
. LIPSIA was developed by the Max-PlanckInstitute of Cognitive Neuroscience, Leipzig, for the data processing and evaluation of functional magnetic resonance images. It is a non-commercial system....
G-PASS: Security Infrastructure for Grid Travelers ⋆ (2007)
Tianchi Ma, Lin Chen, Cho-li Wang
Abstract. Grid travelers are special mobile processes responsible for coordinating resources that are distributed across multiple virtual organizations (VOs). We propose a security infrastructure...
Entanglement of formation from optimal decomposition (2007)
We present a new method of analytically deriving the entanglement of formation of the bipartite mixed state. The method realizes the optimal decomposition families of states. Our method can lead to...
Miniaturised nucleic acid analysis systems (2007)
The design and implementation of miniaturised systems for analysis of nucleic acids from various biological samples has undergone extensive development. Several advances have been made particularly...
Functional Annotation of Genes in Saccharomyces cerevisiae based on Joint Betweenness (2007)
Emmert-Streib, Frank, Chen, Lin, Storey, John
This paper has been withdrawn.
Symmetrized cut-join equation of Marino-Vafa formula (2007)
In this note, we symmetrized the cut-join equation from the proof of Marino-Vafa formula by applying a transcendental changing of variable. One can derive more recursion formulas of Hodge integrals...
Multiqubit entanglement witness (2007)
We introduce a feasible method of constructing the entanglement witness that detects the genuine entanglement of a given pure multiqubit state. We illustrate our method in the scenario of...
Chen, Lin, Chen, Zhang-Liu, Liu, Jian-Hua, Zeng, Zhen-Ling, Ma, Jun-Ying, Jiang, Hong-Xia
Objectives To investigate the occurrence of 16S rRNA methylases conferring high-level resistance to aminoglycosides in Enterobacteriaceae isolated from two pig farms in China. Methods...
Ren, Huibo, Gao, Zhihui, Chen, Lin, Wei, Kaifa, Liu, Jing, Fan, Yijuan, ...
The plant hormone abscisic acid (ABA) accumulates in plant tissues which experience water deficit (stress ABA). This study analysed its accumulation as a function of both synthesis and catabolism in...
A Case Study of Failure Mode Analysis with Text Mining Methods (2007)
The maintenance dataset provided by SunWater contains information about failed assets also known as components and their corresponding failure modes. Currently, extraction of this information from...
Auclair, Dyane, Hopwood, John Joseph, Lemontt, Jeffrey F., Chen, Lin, Byers, Sharon
Degenerative joint disease (DJD) is one aspect of mucopolysaccharidosis VI (MPS VI) pathology that has proven resistant to systemic enzyme replacement therapy (ERT). In this study the effect of...
Auclair, Dyane, Hopwood, John Joseph, Lemontt, Jeffrey F., Chen, Lin, Byers, Sharon
Degenerative joint disease (DJD) is one aspect of mucopolysaccharidosis VI (MPS VI) pathology that has proven resistant to systemic enzyme replacement therapy (ERT). In this study the effect of...
A Case Study of Failure Mode Analysis with Text Mining Methods (2007)
The maintenance dataset provided by SunWater contains information about failed assets also known as components and their corresponding failure modes. Currently, extraction of this information from...
Joint topology control and routing in IEEE 802.11-based multiradio multichannel mesh networks (2007)
Chen, Lin, Zhang, Qian, Li, Minglu, Jia, Weijia
Due to low cost, ease of deployment, increased coverage, and enhanced capacity, multiradio mesh networks that utilize inexpensive and readily available Institute of Electrical and Electronics...
A Case Study of Failure Mode Analysis with Text Mining Methods (2007)
The maintenance dataset provided by SunWater contains information about failed assets also known as components and their corresponding failure modes. Currently, extraction of this information from...
A Case Study of Failure Mode Analysis with Text Mining Methods (2007)
The maintenance dataset provided by SunWater contains information about failed assets also known as components and their corresponding failure modes. Currently, extraction of this information from...
A Case Study of Failure Mode Analysis with Text Mining Methods (2007)
The maintenance dataset provided by SunWater contains information about failed assets also known as components and their corresponding failure modes. Currently, extraction of this information from...
A Case Study of Failure Mode Analysis with Text Mining Methods (2007)
The maintenance dataset provided by SunWater contains information about failed assets also known as components and their corresponding failure modes. Currently, extraction of this information from...
A case study of failure mode analysis with text mining methods (2007)
The maintenance dataset provided by SunWater contains information about failed assets also known as components and their corresponding failure modes. Currently, extraction of this information from...
Chen, Lin, Chen, Zhang-Liu, Liu, Jian-Hua, Zeng, Zhen-Ling, Ma, Jun-Ying, Jiang, Hong-Xia
Objectives To investigate the occurrence of 16S rRNA methylases conferring high-level resistance to aminoglycosides in Enterobacteriaceae isolated from two pig farms in China. Methods...
A case study of failure mode analysis with text mining methods (2007)
The maintenance dataset provided by SunWater contains information about failed assets also known as components and their corresponding failure modes. Currently, extraction of this information from...
Mixed Qubit Cannot Be Universally Broadcast (2006)
We show that there does not exist any universal quantum cloning machine that can broadcast an arbitrary mixed qubit with a constant fidelity. Based on this result, we investigate the dependent...
Asymmetric quantum telecloning of multiqubit states (2006)
We propose a scheme of 1$\to$2 optimal universal asymmetric quantum telecloning of pure multiqubit states. In particular, we first investigate the asymmetric telecloning of arbitrary 2-qubit states...
Localization, Hurwitz Numbers and the Witten Conjecture (2006)
Chen, Lin, Li, Yi, Liu, Kefeng
In this note, we use the method of [3] to give a simple proof of famous Witten conjecture. Combining the coefficients derived in our note and this method, we can derive more recursion formulas of...
Classification of GHZ-type, W-type and GHZ-W-type multiqubit entanglements (2006)
We propose the concept of SLOCC-equivalent basis (SEB) in the multiqubit space. In particular, two special SEBs, the GHZ-type and the W-type basis are introduced. They can make up a more general...
Classification of multipartite entanglement containing infinitely many kinds of states (2006)
Chen, Lin, Chen, Yi-Xin, Mei, Yu-Xue
We give a further investigation of the range criterion and Low-to-High Rank Generating Mode (LHRGM) introduced in \cite{Chen}, which can be used for the classification of $2\times{M}\times{N}$ states...
G-JavaMPI: A Grid Middleware for Transparent MPI Task Migration (2006)
Lin Chen, Tianchi Ma, Cho-li Wang, Francis C. M, Shanping Li
Abstract. Resources in a grid are dynamic, heterogeneous, and widely distributed. End users need a simple and efficient way to aggregate and utilize these diverse resources. We introduce a grid...
In this paper we define the syntax and semantics of a description logic ALCs which is the Description logic ALC combined with modal supervaluation logic for representing vague knowledge. The modal...
Chen, Lin, Lin, Shao-xia, Agha-Majzoub, Rania, Overbergh, Lutgart, Mathieu, Chantal, Chan, Lawrence S.
The keratin-14 IL-4 transgenic (Tg) mouse model of atopic dermatitis (AD) is characterized by skin infiltration of T cells, early up-regulation of Th2 cytokines and late surge of Th1 cytokines. In...
Ren, Huibo, Gao, Zhihui, Chen, Lin, Wei, Kaifa, Liu, Jing, Fan, Yijuan, ...
The plant hormone abscisic acid (ABA) accumulates in plant tissues which experience water deficit (stress ABA). This study analysed its accumulation as a function of both synthesis and catabolism in...
In this paper we define the syntax and semantics of a description logic ALCs which is the Description logic ALC combined with modal supervaluation logic for representing vague knowledge. The modal...
Chen, Lin, Lin, Shao-xia, Agha-Majzoub, Rania, Overbergh, Lutgart, Mathieu, Chantal, Chan, Lawrence S.
The keratin-14 IL-4 transgenic (Tg) mouse model of atopic dermatitis (AD) is characterized by skin infiltration of T cells, early up-regulation of Th2 cytokines and late surge of Th1 cytokines. In...
ECA Rule-Based Workflow Modeling and Implementation for Service Composition (2006)
CHEN, Lin, LI, Minglu, CAO, Jian
Changes in recent business and scientific environment have created a necessity for more efficient and effective workflow infrastructure. With increasing emphasis on Service-oriented architecture,...
Ren, Huibo, Gao, Zhihui, Chen, Lin, Wei, Kaifa, Liu, Jing, Fan, Yijuan, ...
The plant hormone abscisic acid (ABA) accumulates in plant tissues which experience water deficit (stress ABA). This study analysed its accumulation as a function of both synthesis and catabolism in...
Range criterion and classification of true entanglement in $2\times{M}\times{N}$ system (2005)
We propose a range criterion which is a sufficient and necessary condition satisfied by two pure states transformable with each other under reversible stochastic local operations assisted with...
Probabilistically implementing nonlocal operation using non-maximally entangled state (2005)
We develop the probabilistic implementation of a nonlocal gate $\exp{[i\xi{\sigma_{n_A}}\sigma_{n_B}]}$ and $\xi\in[0,\frac\pi4]$, by using a single non-maximally entangled state. We prove that,...
Instance-oriented Security Infrastructure for Grid Travelers ‡ (2005)
Tianchi Ma, Lin Chen, Cho-li Wang, Francis C. M
Grid computing unifies distributed resources via its support for the creation and use of virtual organizations (VOs), where a VO represents a collection of distributed resources to be accessed...
New vernacular housing for the historical districts of Beijing, China / (2005)
Thesis (M.Arch.)--University of Minnesota, 2005.
Thesis (MBus) -- Auckland University of Technology, 2005.
Willis, Simon N., Chen, Lin, Dewson, Grant, Wei, Andrew, Naik, Edwina, Fletcher, Jamie I., ...
Commitment of cells to apoptosis is governed largely by the interaction between members of the Bcl-2 protein family. Its three subfamilies have distinct roles: The BH3-only proteins trigger apoptosis...
Willis, Simon N., Chen, Lin, Dewson, Grant, Wei, Andrew, Naik, Edwina, Fletcher, Jamie I., ...
Commitment of cells to apoptosis is governed largely by the interaction between members of the Bcl-2 protein family. Its three subfamilies have distinct roles: The BH3-only proteins trigger apoptosis...
Willis, Simon N., Chen, Lin, Dewson, Grant, Wei, Andrew, Naik, Edwina, Fletcher, Jamie I., ...
Commitment of cells to apoptosis is governed largely by the interaction between members of the Bcl-2 protein family. Its three subfamilies have distinct roles: The BH3-only proteins trigger apoptosis...
Remote state preparation using non-maximally entangled states (2004)
We present a scheme in which any pure qubit $|\phi=\cos{\theta}|0+\sin{\theta}e^{i\varp hi}|1$ could be remotely prepared by using minimum classical bits and the previously shared non-maximally...
Thesis (M.S.)--State University of New York at Stony Brook, 2004.
Zymogenic and enzymatic properties of the 70-80 loop mutants of factor X/Xa (2004)
Chen, Lin, Manithody, Chandrashekhara, Yang, Likui, Rezaie, Alireza R.
The Ca2+ binding 70–80 loop of factor X (fX) contains one basic (Arg71) and three acidic (Glu74, Glu76, and Glu77) residues whose contributions to the zymogenic and enzymatic properties of the...
On some empirical Bayes and statistical selection and ranking procedures (2003)
The dissertation deals with some empirical Bayes test procedures and statistical selection and ranking procedures. The first two chapters are related to empirical Bayes test procedures. In the first...
Leipzig, University, Diss., 2003.
Chen, Lin, Li, Cuiling, Qiao, Wenhui, Xu, Xiaoling, Deng, Chuxia
Missense mutations in fibroblast growth factor receptor 3 (FGFR3) result in several types of human skeletal dysplasia, including the neonatally lethal dwarfism known as thanatophoric dysplasia. An...
Component-centric approach in a web-based home schooling monitoring system /--Lin Chen. (2000)
Abstract: l. ii.
Effects of Protease inhibitors on the extraction of mushroom tyrosinase /--Lin Chen. (2000)
"Presented to the School of Graduate Studies Department of Chemistry."
Thermophilic enzymes and their impact on milk powder during storage / (2000)
Thesis (Ph.D.)--University of Waikato, 2000.
Gabriele Lohmann, Karsten Muller, Volker Bosch, Heiko Mentzel, Sven Hessler, Lin Chen, ...
This report gives a short overview of the software system LIPSIA. LIPSIA was developed by the MaxPlanck-Institute of Cognitive Neuroscience, Leipzig, for the data processing and evaluation of...
Analysis of the interaction between chk1 and 14-3-3 in the DNA damage checkpoint pathway / (2000)
"Graduate Program in Biochemistry."
Zhou, Yong-Xing, Xu, Xiaoling, Chen, Lin, Li, Cuiling, Brodie, Steven G., Deng, Chu-Xia
Pfeiffer syndrome is a classic form of craniosynostosis that is caused by a proline→arginine substitution at amino acid 252 (Pro252Arg) in fibroblast growth factor receptor 1 (FGFR1). Here we show...
Jiongjiong Wang, Tiangang Zhou, Maolin Qiu, Antao Du, Kui Cai, Zhanli Wang, ...
Abstract: Recent imaging studies indicated the existence of two visual pathways in humans: a ventral stream for object and form vision and a dorsal stream for spatial and motion vision. The present...
James T Todd, Lin Chen, J Farley Norman
Abstract. A match-to-sample task was performed, in which observers compared configurations of line segments presented stereoscopically in different three-dimensional orientations. Several different...
Improvements in abrasive waterjet cutting of ceramics through controlled head oscillation (1997)
Includes bibliographical references (p. 136-144)
On the Power of Some PRAM Models (1997)
The focus here is the power of some underexplored CRCW PRAMs, which are strictly more powerful than exclusive write PRAM but strictly less powerful than BSR. We show that some problems can be solved...
Photocopy of typescript.
The image of the cultural revolution of China [microform] / (1995)
Thesis--PlanB (M.S.)--University of Wisconsin--Stout, 1995.
A Petri net based framework for database query [microform] / (1995)
Thesis (M. Sc.)--University of Regina, 1994.
Submitted to the School of Biochemistry. Bibliography : leaves 128-154.
Thesis (M.A. Sc.)--University of Toronto, 1994.
A Petri net based framework for database query / (1994)
Thesis (M. Sc.)--University of Regina, 1994.
MO studies on the gas phase acidities of the cyanocyclopentadienes /--by Lin Chen. (1992)
Thesis (M.S.)--Michigan Technological University, 1992.
Thesis (Ph. D.)--University of Detroit Mercy, 1992.
Ch'ing dynasty furniture and its influences / (1973)
Thesis (M.A.)--City College of New York, 1973. (Department of Art).
A Fast Longest Common Subsequence Algorithm for Biosequences Alignment (1970)
Searching for the longest common substring (LCS) of biosequences is one of the most important tasks in Bioinformatics. A fast algorithm for LCS problem named FAST_LCS is presented. The algorithm...
The Sequence of the Human Genome (1304)
T He, H Uman, G Enome, J. Craig Venter, Mark D. Adams, Eugene W. Myers, ...
CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex
Hsieh, James J.-D., Zhou, Sifang, Chen, Lin, Young, David B., Hayward, S. Diane
CBF1 is a member of the CSL family of DNA binding factors, which mediate either transcriptional repression or transcriptional activation. CSL proteins play a central role in Notch signaling and in...
Parrish, Jay, Metters, Helen, Chen, Lin, Xue, Ding
Demonstrating in vivo interaction of two important biomolecules and the relevance of the interaction to a biological process have been difficult issues in biomedical research. Here, we report the use...
Zhou, Sifang, Fujimuro, Masahiro, Hsieh, James J.-D., Chen, Lin, Miyamoto, Alison, Weinmaster, Gerry, ...
Notch proteins are transmembrane receptors that mediate intercell communication and direct individual cell fate decisions. The activated intracellular form of Notch, NotchIC, translocates to the...
Semmes, O. John, Chen, Lin, Sarisky, Robert T., Gao, Zhigang, Zhong, Ling, Hayward, S. Diane
The Epstein-Barr virus (EBV) Zta and Mta regulatory proteins were previously found to be required for efficient replication of oriLyt in cotransfection-replication assays, but the contribution of Mta...
A Role for SKIP in EBNA2 Activation of CBF1-Repressed Promoters
Zhou, Sifang, Fujimuro, Masahiro, Hsieh, James J.-D., Chen, Lin, Hayward, S. Diane
EBNA2 is essential for Epstein-Barr virus (EBV) immortalization of B lymphocytes. EBNA2 functions as a transcriptional activator and targets responsive promoters through interaction with the cellular...
Global perception in small brains: Topological pattern recognition in honey bees
Chen, Lin, Zhang, Shaowu, Srinivasan, Mandyam V.
A series of experiments with honey bees demonstrate that their small brains nevertheless possess the ability for topological perception. Bees rapidly learned to discriminate patterns that are...
Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage
Chen, Lin, Liu, Ting-Hsiu, Walworth, Nancy C.
The protein kinase Chk1 is required for cell cycle arrest in response to DNA damage. We have found that the 14-3-3 proteins Rad24 and Rad25 physically interact with Chk1 in fission yeast. Association...
Nucleotide sequence of a multiple-copy gene for the B protein of photosystem II of a cyanobacterium
Mulligan, Bernard, Schultes, Neil, Chen, Lin, Bogorad, Lawrence
Chloroplast photogene 32 codes for the 32-kilodalton triazine herbicide-binding protein at the B site of electron transport in photosystem II of the photosynthetic apparatus—its product is the B...
Chen, Lin, Adar, Rivka, Yang, Xiao, Monsonego, Efrat O., Li, Cuiling, Hauschka, Peter V., ...
Missense mutations in fibroblast growth factor receptor 3 (FGFR3) result in several human skeletal dysplasias, including the most common form of dwarfism, achondroplasia. Here we show that a...
Kinase peptide specificity: Improved determination and relevance to protein phosphorylation
Fujii, Koichi, Zhu, Guozhi, Liu, Yin, Hallam, John, Chen, Lin, Herrero, Juan, ...
Specificity of phosphorylation is critical to signal transduction. Recent emphasis on colocalization of substrate and kinase has eclipsed emphasis on peptide specificity, i.e., kinase preference for...
Hahn, Paul, Qian, Ying, Dentchev, Tzvete, Chen, Lin, Beard, John, Harris, Zena Leah, ...
Mechanisms of brain and retinal iron homeostasis have become subjects of increased interest after the discovery of elevated iron levels in brains of patients with Alzheimer's disease and retinas of...
Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice
Shan, Dandan, Chen, Lin, Njardarson, Jon T., Gaul, Christoph, Ma, Xiaojing, Danishefsky, Samuel J., ...
Tumor metastasis is the most common cause of death in cancer patients. Here, we show that two, fully synthetic migrastatin analogues, core macroketone and core macrolactam, are potent inhibitors of...
Willis, Simon N., Chen, Lin, Dewson, Grant, Wei, Andrew, Naik, Edwina, Fletcher, Jamie I., ...
Commitment of cells to apoptosis is governed largely by the interaction between members of the Bcl-2 protein family. Its three subfamilies have distinct roles: The BH3-only proteins trigger apoptosis...
Relaxed Significance Criteria for Linkage Analysis
Linkage analysis involves performing significance tests at many loci located throughout the genome. Traditional criteria for declaring a linkage statistically significant have been formulated with...
CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex
Hsieh, James J.-D., Zhou, Sifang, Chen, Lin, Young, David B., Hayward, S. Diane
CBF1 is a member of the CSL family of DNA binding factors, which mediate either transcriptional repression or transcriptional activation. CSL proteins play a central role in Notch signaling and in...
Parrish, Jay, Metters, Helen, Chen, Lin, Xue, Ding
Demonstrating in vivo interaction of two important biomolecules and the relevance of the interaction to a biological process have been difficult issues in biomedical research. Here, we report the use...
Zhou, Sifang, Fujimuro, Masahiro, Hsieh, James J.-D., Chen, Lin, Miyamoto, Alison, Weinmaster, Gerry, ...
Notch proteins are transmembrane receptors that mediate intercell communication and direct individual cell fate decisions. The activated intracellular form of Notch, NotchIC, translocates to the...
Semmes, O. John, Chen, Lin, Sarisky, Robert T., Gao, Zhigang, Zhong, Ling, Hayward, S. Diane
The Epstein-Barr virus (EBV) Zta and Mta regulatory proteins were previously found to be required for efficient replication of oriLyt in cotransfection-replication assays, but the contribution of Mta...
A Role for SKIP in EBNA2 Activation of CBF1-Repressed Promoters
Zhou, Sifang, Fujimuro, Masahiro, Hsieh, James J.-D., Chen, Lin, Hayward, S. Diane
EBNA2 is essential for Epstein-Barr virus (EBV) immortalization of B lymphocytes. EBNA2 functions as a transcriptional activator and targets responsive promoters through interaction with the cellular...
Global perception in small brains: Topological pattern recognition in honey bees
Chen, Lin, Zhang, Shaowu, Srinivasan, Mandyam V.
A series of experiments with honey bees demonstrate that their small brains nevertheless possess the ability for topological perception. Bees rapidly learned to discriminate patterns that are...
Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage
Chen, Lin, Liu, Ting-Hsiu, Walworth, Nancy C.
The protein kinase Chk1 is required for cell cycle arrest in response to DNA damage. We have found that the 14-3-3 proteins Rad24 and Rad25 physically interact with Chk1 in fission yeast. Association...
Nucleotide sequence of a multiple-copy gene for the B protein of photosystem II of a cyanobacterium
Mulligan, Bernard, Schultes, Neil, Chen, Lin, Bogorad, Lawrence
Chloroplast photogene 32 codes for the 32-kilodalton triazine herbicide-binding protein at the B site of electron transport in photosystem II of the photosynthetic apparatus—its product is the B...
Chen, Lin, Adar, Rivka, Yang, Xiao, Monsonego, Efrat O., Li, Cuiling, Hauschka, Peter V., ...
Missense mutations in fibroblast growth factor receptor 3 (FGFR3) result in several human skeletal dysplasias, including the most common form of dwarfism, achondroplasia. Here we show that a...
Kinase peptide specificity: Improved determination and relevance to protein phosphorylation
Fujii, Koichi, Zhu, Guozhi, Liu, Yin, Hallam, John, Chen, Lin, Herrero, Juan, ...
Specificity of phosphorylation is critical to signal transduction. Recent emphasis on colocalization of substrate and kinase has eclipsed emphasis on peptide specificity, i.e., kinase preference for...
Hahn, Paul, Qian, Ying, Dentchev, Tzvete, Chen, Lin, Beard, John, Harris, Zena Leah, ...
Mechanisms of brain and retinal iron homeostasis have become subjects of increased interest after the discovery of elevated iron levels in brains of patients with Alzheimer's disease and retinas of...
Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice
Shan, Dandan, Chen, Lin, Njardarson, Jon T., Gaul, Christoph, Ma, Xiaojing, Danishefsky, Samuel J., ...
Tumor metastasis is the most common cause of death in cancer patients. Here, we show that two, fully synthetic migrastatin analogues, core macroketone and core macrolactam, are potent inhibitors of...
Willis, Simon N., Chen, Lin, Dewson, Grant, Wei, Andrew, Naik, Edwina, Fletcher, Jamie I., ...
Commitment of cells to apoptosis is governed largely by the interaction between members of the Bcl-2 protein family. Its three subfamilies have distinct roles: The BH3-only proteins trigger apoptosis...
Relaxed Significance Criteria for Linkage Analysis
Linkage analysis involves performing significance tests at many loci located throughout the genome. Traditional criteria for declaring a linkage statistically significant have been formulated with...
Luo, Hao, Ni, Jing-Tian, Li, Zhi-Hao, Li, Xiao-Ou, Zhang, Da-Ren, Zeng, Fan-Gang, ...
In tonal languages such as Mandarin Chinese, a lexical tone carries semantic information and is preferentially processed in the left brain hemisphere of native speakers as revealed by the functional...
Chen, Lin, Martinez, O, Venkataramani, P, Lin, S-X, Prabhakar, B S, Chan, L S
Atopic dermatitis is a chronic inflammatory skin disease characterized by inflammatory cell infiltration in the skin. In order to assess the roles of inflammatory cells in this disease, we analysed...
Guo, Liang, Han, Aidong, Bates, Darren L., Cao, Jue, Chen, Lin
Glutamine-rich sequences exist in a wide range of proteins across multiple species. A subset of glutamine-rich sequences has been shown to form amyloid fibers implicated in human diseases. The...
Contribution of Polycomb Homologues Bmi-1 and Mel-18 to Medulloblastoma Pathogenesis▿ †
Wiederschain, Dmitri, Chen, Lin, Johnson, Brett, Bettano, Kimberly, Jackson, Dowdy, Taraszka, John, ...
Bmi-1 and Mel-18 are structural homologues that belong to the Polycomb group of transcriptional regulators and are believed to stably maintain repression of gene expression by altering the state of...
Uren, Rachel T., Dewson, Grant, Chen, Lin, Coyne, Stephanie C., Huang, David C.S., Adams, Jerry M., ...
The Bcl-2 family regulates apoptosis by controlling mitochondrial integrity. To clarify whether its prosurvival members function by sequestering their Bcl-2 homology 3 (BH3)–only ligands or their...
Zymogenic and enzymatic properties of the 70–80 loop mutants of factor X/Xa
Chen, Lin, Manithody, Chandrashekhara, Yang, Likui, Rezaie, Alireza R.
The Ca2+ binding 70–80 loop of factor X (fX) contains one basic (Arg71) and three acidic (Glu74, Glu76, and Glu77) residues whose contributions to the zymogenic and enzymatic properties of the...
Wilson-Annan, Julie, O'Reilly, Lorraine A., Crawford, Simon A., Hausmann, George, Beaumont, Jennifer G., Parma, Loes P., ...
Prosurvival Bcl-2–like proteins, like Bcl-w, are thought to function on organelles such as the mitochondrion and to be targeted to them by their hydrophobic COOH-terminal domain. We unexpectedly...
Yang, Xiao, Chen, Lin, Xu, Xiaoling, Li, Cuiling, Huang, Cuifen, Deng, Chu-Xia
Endochondral ossification begins from the condensation and differentiation of mesenchymal cells into cartilage. The cartilage then goes through a program of cell proliferation, hypertrophic...
Chick hair cells do not exhibit voltage-dependent somatic motility
He, David Z Z, Beisel, Kirk W, Chen, Lin, Ding, Da-Lian, Jia, Shuping, Fritzsch, Bernd, ...
It is generally believed that mechanical amplification by cochlear hair cells is necessary to enhance the sensitivity and frequency selectivity of hearing. In the mammalian ear, the basis of cochlear...
Luan, Yi, Yu, Xiu-Ping, Yang, Ning, Frenkel, Sally, Chen, Lin, Liu, Chuan-ju
Id proteins play important roles in osteogenic differentiation; however, the molecular mechanism remains unknown. In this study, we established that inhibitor of differentiation (Id) proteins,...
Global topological dominance in the left hemisphere
Wang, Bo, Zhou, Tian Gang, Zhuo, Yan, Chen, Lin
A series of experiments with right-handers demonstrated that the left hemisphere (LH) is reliably and consistently superior to the right hemisphere (RH) for global topological perception. These...
A GEOMETRICAL METHOD ON MULTIDIMENSIONAL DYNAMIC CREDIT EVALUATION
YING ZHANG, LIN CHEN, ZONGFANG ZHOU, YONG SHI
In this paper, we first discuss the space frame of multidimensional dynamic credit evaluation (MDCE) theoretically, and then propose the conception of identical credit status and pseudo-identical...
Varella-Garcia, Marileila, Chen, Lin, Powell, Roger L., Hirsch, Fred R., Kennedy, Timothy C., Keith, Robert, ...
Rationale: Lung cancer is a multistep process that is preceded and often accompanied by molecular cytogenetic lesions in benign bronchial epithelium, the precise character, extent and timing of which...
Lukas, Thomas J, Miao, Haixi, Chen, Lin, Riordan, Sean M, Li, Wenjun, Crabb, Andrea M, ...
Comparison of gene expression in normal and glaucomatous eyes from Caucasian American and African American donors reveals differences that might reflect different susceptibility to glaucoma.
Kirsch, Stefan, Münch, Claudia, Jiang, Zhaoshi, Cheng, Ze, Chen, Lin, Batz, Christiane, ...
Human chromosomal regions enriched in segmental duplications are subject to extensive genomic reorganization. Such regions are particularly informative for illuminating the evolutionary history of a...
Genomic characterization of putative allergen genes in peach/almond and their synteny with apple
Chen, Lin, Zhang, Shuiming, Illa, Eudald, Song, Lijuan, Wu, Shandong, Howad, Werner, ...
Dey, Raja, Ji, Kunmei, Liu, Zhigang, Chen, Lin
Interleukine-3 (IL-3) binds its receptor and initiates a cascade of signaling processes that regulate the proliferation and differentiation of hematopoietic cells. To understand the detailed...
cAMP Inhibits Cell Migration by Interfering with Rac-induced Lamellipodium Formation*
Chen, Lin, Zhang, J. Jillian, Huang, Xin-Yun
Cell migration is critical for animal development and physiological as well as pathological responses. One important step during cell migration is the formation of lamellipodia at the leading edge of...
Li, Changqing, Grobmyer, Stephen R., Massol, Nicole, Liang, Xiaoping, Zhang, Qizhi, Chen, Lin, ...
This article presents a pilot study of multispectral diffuse optical tomography for noninvasively imaging volume fraction and mean size of cellular scattering components in the breast. Cellular...
Sequencing human–gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites
Girirajan, Santhosh, Chen, Lin, Graves, Tina, Marques-Bonet, Tomas, Ventura, Mario, Fronick, Catrina, ...
The gibbon genome exhibits extensive karyotypic diversity with an increased rate of chromosomal rearrangements during evolution. In an effort to understand the mechanistic origin and implications of...
GLI3 Repressor Controls Nephron Number via Regulation of Wnt11 and Ret in Ureteric Tip Cells
Cain, Jason E., Islam, Epshita, Haxho, Fiona, Chen, Lin, Bridgewater, Darren, Nieuwenhuis, Erica, ...
Truncating GLI3 mutations in Pallister-Hall Syndrome with renal malformation suggests a requirement for Hedgehog signaling during renal development. HH-dependent signaling increases levels of GLI...
Language regions of brain are operative in color perception
Ting Siok, Wai, Kay, Paul, Wang, William S. Y., Chan, Alice H. D., Chen, Lin, Luke, Kang-Kwong, ...
The effect of language on the categorical perception of color is stronger for stimuli in the right visual field (RVF) than in the left visual field, but the neural correlates of the behavioral RVF...