Lin Feng

Publication List Details

Period

1997 - 2009

Number

20

Co-Authors

A STATISTICAL APPROACH FOR IDENTIFYING DIFFERENTIALLY EXPRESSED GENES IN TIME-COURSE CDNA MICROARRAY EXPERIMENT WITHOUT REPLICATE (2009)

Xu Han, Lin Feng

Replication of time series in microarray experiments is costly. To analyze time series data with no replicate, many model-specific approaches have been proposed. However, they fail to identify the...

MERIT40 facilitates BRCA1 localization and DNA damage repair (2009)

Feng, Lin, Huang, Jun, Chen, Junjie

The product of breast cancer susceptibility gene 1, BRCA1, plays pivotal roles in the maintenance of genomic integrity. Mounting evidence indicates that BRCA1 associates with many proteins or protein...

A Volume Modeling Component of CAD (2008)

Zhou Jianwen, Lin Feng, Seah Hock Soon

Abstract: This paper presents a framework we have developed for modeling and manipulation of volumetric data sets. It is a set of new functions integrated into a CAD system. We shall address freeform...

Empirical Term Weighting (2008)

Kyoji Umemura, Yoshiyuki Takeda, Michiko Tanaka, Lin Feng, Eiko Yamamoto

Our system used an empirical method for estimating term weights directly from relevance judgements, avoiding various standard but potentially troublesome assumptions. It is common to assume, for...

Meta-analysis of prophylactic corticosteroid use in post-ERCP pancreatitis (2008)

Zheng Minghua, Bai Jianling, Yuan Bosi, Lin Feng, You Jie, Lu Mingqin, ...

Abstract Background Acute pancreatitis is a common complication of endoscopic retrograde cholangiopancreatography and benefit of pharmacological treatment is unclear. Although prophylactic use of...

RKTG sequesters B-Raf to the Golgi apparatus and inhibits the proliferation and tumorigenicity of human malignant melanoma cells (2008)

Fan, Fengjuan, Feng, Lin, He, Jing, Wang, Xiao, Jiang, Xiaomeng, Zhang, Yixuan, ...

Raf kinase trapping to Golgi (RKTG) is a newly characterized negative regulator of the Ras–Raf–mitogen-activated and extracellular signal-regulated kinase kinase (MEK)–extracellular...

Predicting peptides binding to MHC class II molecules using multi-objective evolutionary algorithms (2007)

Rajapakse, Menaka, Schmidt, Bertil, Feng, Lin, Brusic, Vladimir

Abstract Background Peptides binding to Major Histocompatibility Complex (MHC) class II molecules are crucial for initiation and regulation of immune responses. Predicting peptides that bind to a...

Parallel Detection of Regulatory Elements with gMP (2007)

Bertil Schmidt, Lin Feng

The detection of regulatory elements from a large set of regulatory regions is a challenging problem in computational genomics. However, computational methods to extract this biological meaningful...

Quantification of human bocavirus in lower respiratory tract infections in China (2007)

Lin Feng, Zeng Aiping, Yang Ningmin, Lin Haiyan, Yang En, Wang Shengqi, ...

Abstract A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A...

Detection and identification of enterohemorrhagic Escherichia coli O157:H7 and Vibrio cholerae O139 using oligonucleotide microarray (2007)

Jin Da-Zhi, Xu Xiao-Jing, Chen Su-Hong, Wen Si-Yuan, Ma Xue-En, Zhang Zheng, ...

Abstract Background The rapid and accurate detection and identification of the new subtype of the pathogens is crucial for diagnosis, treatment and control of the contagious disease outbreak. Here,...

In silico modelling of hormone response elements (2006)

Stepanova Maria, Lin Feng, Lin Valerie

Abstract Background An important step in understanding the conditions that specify gene expression is the recognition of gene regulatory elements. Due to high diversity of different types of...

Santoso Y: Development of distributed bioinformatics applications with GMP. Concurrency and Computation: Practice and Experience (2004)

Bertil Schmidt, Lin Feng, Amey Laud

We present the design and use of gMP as a tool for developing distributed bioinformatics applications. gMP is a purely Java-based interface that adds MPI-like message-passing and collective...

Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting (1999)

Dao, Diem, Walsh, Colum P., Yuan, Luwa, Gorelov, Dmitri, Feng, Lin, Hensle, Terrence, ...

WT2 is defined by maternal-specific loss of heterozygosity (LOH) on chromosome 11p15.5 in Wilms’ tumors (WTs). The imprinted H19 gene, in this region, is silenced and hypermethylated in most WTs,...

Apolipoprotein E epsilon4 and incidence of Alzheimer disease in a community population of older persons. (1997)

Evans, Denis A., Beckett, Laurel A., Field, Terry S., Feng, Lin, Albert, Marilyn S., Bennett, David A., ...

OBJECTIVE: To examine the relation between apolipoprotein E status and risk of Alzheimer disease (AD) in a defined population and estimate the fraction of incident AD attributable to the epsilon4...

Spatial regulation of Raf kinase signaling by RKTG

Feng, Lin, Xie, Xiaoduo, Ding, Qiurong, Luo, Xiaolin, He, Jing, Fan, Fengjuan, ...

Subcellular compartmentalization has become an important theme in cell signaling such as spatial regulation of Ras by RasGRP1 and MEK/ERK by Sef. Here, we report spatial regulation of Raf kinase by...

A CELLULAR AUTOMATA MODEL FOR A LEARNING PROCESS

MING-FENG HE, CHENG-RUI DENG, LIN FENG, BO-WEN TIAN

Ideas on educational psychology suggest that a learning process occurs when people participate within social communities. A model is constructed based on two primary factors in the learning process :...

MERIT40 facilitates BRCA1 localization and DNA damage repair

Feng, Lin, Huang, Jun, Chen, Junjie

The product of breast cancer susceptibility gene 1, BRCA1, plays pivotal roles in the maintenance of genomic integrity. Mounting evidence indicates that BRCA1 associates with many proteins or protein...