Lin Wang

Publication List Details

Period

1971 - 2009

Number

127

Co-Authors

(1-Institute of Remote Sensing and GIS, Peking University,China,100871) (2- Bureau of Transportation Xinjiang Uyghur Autonomous Region,China.830000) (2009)

Lin Wang, Qiming Qin, Shihong Du, Dezhi Chen, Jianwei Tao

Abstract: In the paper, we present an approach of multi-resolution analysis to extract road information from high resolution imagery. Firstly, high resolution imagery is divided into a series of...

Integrative Decomposition Procedure and Kappa Statistics for the Distinguished Single Molecular Network Construction and Analysis (2009)

Lin Wang, Ying Sun, Minghu Jiang, Xiguang Zheng

Our method concentrates on and constructs the distinguished single gene network. An integrated method was proposed based on linear programming and a decomposition procedure with integrated analysis...

Hybrid Iteration Method for Common Fixed Points of a Finite Family of Nonexpansive Mappings in Banach Spaces (2009)

Lin Wang, Yi-Juan Chen, Rong-Chuan Du

Let E be a real uniformly convex Banach space, and let{Ti:i∈I} be N nonexpansive mappings from E into itself with...

5-Bromo-1-methylindolin-2-one (2009)

Mao-Sen Yuan, Qi Shuai, Lin Wang, Xiao-Zhou Li, Rui-Jin Yu

The title molecule, C9H8BrNO, approximates a full planar conformation. The interplanar angle between the benzene and five-membered rings of the indoline system is 1.38 (1)°. There is an...

Integrative Decomposition Procedure and Kappa Statistics for the Distinguished Single Molecular Network Construction and Analysis (2009)

Lin Wang, Ying Sun, Minghu Jiang, Xiguang Zheng

Our method concentrates on and constructs the distinguished single gene network. An integrated method was proposed based on linear programming and a decomposition procedure with integrated analysis...

Hybrid Iteration Method for Common Fixed Points of a Finite Family of Nonexpansive Mappings in Banach Spaces (2009)

Lin Wang, Yi-Juan Chen, Rong-Chuan Du

Let E be a real uniformly convex Banach space, and let{Ti:i∈I} be N nonexpansive mappings from E into itself with F={x∈E:Tix=x, i∈I}≠ϕ, where I={1,2,…,N}. From an arbitrary initial point...

Generalized transfer matrix theory on electronic transport through graphene waveguide (2008)

Li, Haidong, Wang, Lin, Lan, Zhihuan, Zheng, Yisong

In the effective mass approximation, electronic property in graphene can be characterized by the relativistic Dirac equation. Within such a continuum model we investigate the electronic transport...

Toxicity of CdSe Nanoparticles in Caco-2 Cell Cultures (2008)

Wang, Lin, Nagesha, Dattatri K, Selvarasah, Selvapraba, Dokmeci, Mehmet R, Carrier, Rebecca L

Abstract Background Potential routes of nanomaterial exposure include inhalation, dermal contact, and ingestion. Toxicology of inhalation of ultra-fine particles has been extensively studied;...

Suppressed conductance in a metallic graphene nano-junction (2008)

Li, Haidong, Wang, Lin, Zheng, Yisong

The linear conductance spectrum of a metallic graphene junction formed by interconnecting two gapless graphene nanoribbons is calculated. A strong conductance suppression appears in the vicinity of...

A New Computational Method of Input Selection for Stock Market Forecasting with Neural Networks (2008)

Wei Huang, Shouyang Wang, Lean Yu, Yukun Bao, Lin Wang

Abstract. We propose a new computational method of input selection for stock market forecasting with neural networks. The method results from synthetically considering the special feature of input...

Up-regulation of multiple proteins and biological processes during maxillary expansion in rats (2008)

Ma, Junqing, Wu, Yunxia, Zhang, Weibing, Smales, Roger J, Huang, You, Pan, Yongchu, ...

Abstract Background Maxillary expansion (ME) is a common practice in orthodontics that aims to increase the constricted maxillary arch width. Relapse often occurs, however, and better treatment...

Ultrafine-grained copper prepared by spark plasma sintering process (2008)

Zhang, Zhao-Hui, Wang, Fu-Chi, Wang, Lin, Li, Shu-Kui

Spark plasma sintering (SPS) parameters including pressure, temperature, holding time and heating rate were considered and optimized to investigate the sintering process of bulk copper. The...

A Novel Improvement of Neural Network Classification Using Further Division of Partition Space (2008)

Lin Wang, Zhenxiang Chen, Lizhi Peng

Abstract. Further Division of Partition Space (FDPS) is a novel technique for neural network classification. Partition space is a space that is used to categorize data sample after sample, which are...

Growth, differentiation, transplantation and survival of human skeletal myofibers on biodegradable scaffolds (2008)

Shansky, Janet, Wang, Lin, Fast, Loren, ...

Skeletal muscle transplantation strategies for muscle repair or gene therapy involve either the injection of proliferating myoblasts followed by fusion with host myofibers or implantation of ex vivo...

Comparative evaluation of micro-implant and headgear anchorage used with a pre-adjusted appliance system (2008)

Ma, Junqing, Wang, Lin, Zhang, Weibing, Chen, Wenjing, Zhao, Chunyang, Smales, Roger J.

The aim of this study was to compare and evaluate the anchorage effectiveness of using either micro-implants or extraoral headgear with the McLaughlin–Bennett–Trevisi (MBT) system. Thirty young...

Common genetic variation in calpain-10 gene (CAPN10) and diabetes risk in a multi-ethnic cohort of American postmenopausal women (2007)

Song, Yiqing, You, Nai-chieh, Hsu, Yi-Hsiang, Sul, James, Wang, Lin, Tinker, Lesley, ...

Calpain-10 (CAPN10) protein may play a role in glucose metabolisms, pancreatic β-cell insulin secretion and thermogenesis. Emerging evidence has implicated a role of CAPN10 genetic variants in the...

Raman spectroscopy study of carbon nanotube peapods excited by near-IR laser under high pressure (2007)

Zou, Yonggang, Liu, Bingbing, Yao, Mingguang, Hou, Yuanyuan, Wang, Lin, Yu, Shidan, ...

A resonant Raman spectroscopy study has been carried out under high pressure, using a diamond anvil cell, on carbon nanotube peapods (C-60@SWNT) synthesized in high yield in our laboratory. The Raman...

Synthesis and investigation of deoxyribonucleic acid/locked nucleic acid chimeric molecular beacons (2007)

Yang, Chaoyong James, Wang, Lin, Wu, Yanrong, Kim, Youngmi, Medley, Colin D., Lin, Hui, ...

To take full advantage of locked nucleic acid (LNA) based molecular beacons (LNA-MBs) for a variety of applications including analysis of complex samples and intracellular monitoring, we have...

An Iteration Method for Nonexpansive Mappings in Hilbert Spaces (2007)

Lin Wang

In real Hilbert space H, from an arbitrary initial point x0∈H, an explicit iteration scheme is defined as follows: xn+1=αnxn+(1−αn)Tλn+1xn,n≥0, where Tλn+1xn=Txn−λn+1μF(Txn), T:H→H is...

Angiogenesis enhances factor IX delivery and persistence from retrievable human bioengineered muscle implants (2006)

Vandenburgh, Herman, Callewaert, Nico, Mertens, Nico, Shansky, Janet, Wang, Lin, ...

Human muscle progenitor cells transduced with lentiviral vectors secreted high levels of blood clotting factor IX (FIX). When bioengineered into postmitotic myofibers as human bioartificial muscles...

Validating ORA-SS data models using Alloy (2006)

Wang, Lin, Dobbie, Gill, Sun, Jing, Groves, Lindsay

An open access copy of this article is available and complies with the copyright holder/publisher conditions.

An analysis of the Chinese stock market (2006)

Wang, Lin (Linda)

Project (M.A.) - Faculty of Business Administration - Simon Fraser University

An Iteration Method for Nonexpansive Mappings in Hilbert Spaces (2006)

Lin Wang

In real Hilbert space H, from an arbitrary initial point x0∈H, an explicit iteration scheme is defined as follows: xn+1=αnxn+(1−αn)Tλn+1xn,n≥0,...

Validating ORA-SS Data Models using Alloy (2006)

Lin Wang, Gillian Dobbie, Jing Sun

Semistructured data is typically represented using XML. However, little semantic information can be captured using XML. Other data models, such as the Object Relationship Attribute data model for...

Validating ORA-SS Data Models using Alloy (2006)

Lin Wang, Gill Dobbie, Jing Sun, Lindsay Groves, Lin Wang, Gillian Dobbie, ...

Semistructured data is typically represented using XML. However, little semantic information can be captured using XML. Other data models, such as the Object Relationship Attribute data model for...

Significance of COX-2 expression in human esophageal squamous cell carcinoma (2006)

Zhi, Huiying, Wang, Lin, Zhang, Jian, Zhou, Chuannong, Ding, Fang, Luo, Aiping, ...

Cyclooxygenase-2 (COX-2) is well established to play an important role in the tumorigenesis of a variety of human cancers; however, the function of COX-2 in the development of esophageal squamous...

A variance component analysis on recombination rate in the COGA pedigrees (2005)

Wang, Lin, Xu, Xin

Abstract We estimated the crossover frequency in 1,232 gametes from 356 subjects in pedigrees from the Collaborative Study on the Genetics on Alcoholism. We examined the effect of covariates...

Radiative Effects on the Chiral Square (2005)

Ponton, Eduardo, Wang, Lin

We consider general field theories in six dimensions, with two of the dimensions compactified on a T_{2}/Z_{4} orbifold. Six-dimensional Weyl fermions propagating on this background give rise to a...

SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management (2005)

Wang, Lin, Liu, Simin, Niu, Tianhua, Xu, Xin

Abstract Background Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. Selection and...

Trajectories of adolescent depression and gender/racial disparity (2005)

Wang, Lin.

Thesis (M.A.)--University of North Carolina at Chapel Hill, 2006.

FLUORESCENT NOBLE METAL NANOCLUSTER Approved by: (2005)

Jie Zheng, M. Dickson, A. El-sayed, Dr. L. Andrew Lyon, ...

dedicated to my parents for their contributions to the society…… ACKNOWLDGMENTS I would like to thank my advisor Dr. Robert M. Dickson for bringing me to this amazing field and endless support of...

Significance of COX-2 expression in human esophageal squamous cell carcinoma (2005)

Zhi, Huiying, Wang, Lin, Zhang, Jian, Zhou, Chunnong, Ding, Fang, Luo, Aiping, ...

Cyclooxygenase-2 (COX-2) is well established to play an important role in the tumorigenesis of a variety of human cancers; however, the function of COX-2 in the development of esophageal squamous...

Antibody array for the detection of protein phosphorylation & localization and application to dissect activities of different signaling pathways (2004)

Wang, Lin

This thesis Develop a new suitable nano-gold mediated silver antibody microarray technology. Application examples show that the antibody array efficently detects differences in protein and...

A Large-Scale Candidate Gene Association Study on Preterm Delivery: Application of High-Throughput Genotyping Technology and Advanced Statistical Methods (2004)

Hao, Ke, Wang, Xiaobin, Niu, Tianhua, Xu, Xin, Li, Ang, Chang, Weili, ...

Preterm delivery (PTD) is the leading cause of infant mortality and morbidity worldwide. The etiology of PTD is largely unknown but is believed to be complex, encompassing multiple genetic and...

A candidate gene association study on preterm delivery: application of high-throughput genotyping technology and advanced statistical methods (2004)

Hao, Ke, Wang, Xiaobin, Niu, Tianhua, Xu, Xin, Li, Ang, Chang, Weili, ...

Preterm delivery (PTD) is the leading cause of infant mortality and morbidity worldwide. The etiology of PTD is largely unknown but is believed to be complex, encompassing multiple genetic and...

A Large-Scale Candidate Gene Association Study on Preterm Delivery: Application of High-Throughput Genotyping Technology and Advanced Statistical Methods (2004)

Hao, Ke, Wang, Xiaobin, Niu, Tianhua, Xu, Xin, Li, Ang, Chang, Weili, ...

Preterm delivery (PTD) is the leading cause of infant mortality and morbidity worldwide. The etiology of PTD is largely unknown but is believed to be complex, encompassing multiple genetic and...

Performance analysis of an integrated CS/PS services CDMA system (2003)

Wang, Lin, Aghvami, Hamid, Chambers, William G., Pérez Romero, Jordi, Sallent Roig, Oriol, Dohler, Mischa

An analytical model is developed to investigate integrated CS/PS CDMA cellular systems with SIR-based power control. Because packet data are not very sensitive to delay, a defer-first-transmission...

Performance analysis of an integrated CS/PS services CDMA system (2003)

Wang, Lin, Aghvami, Hamid, Chambers, William G., Pérez Romero, Jordi, Sallent Roig, Oriol, Dohler, Mischa

An analytical model is developed to investigate integrated CS/PS CDMA cellular systems with SIR-based power control. Because packet data are not very sensitive to delay, a defer-first-transmission...

Performance analysis of an integrated CS/PS services CDMA system (2003)

Wang, Lin, Aghvami, Hamid, Chambers, William G., Pérez Romero, Jordi, Sallent Roig, Oriol, Dohler, Mischa

An analytical model is developed to investigate integrated CS/PS CDMA cellular systems with SIR-based power control. Because packet data are not very sensitive to delay, a defer-first-transmission...

E-Commerce Security Resource (2002)

Fillia Makedon, Carey Heckman, Adeel Meer, Tilmann Steinberg, Lin Wang, Song Ye

As the Internet continues to play an increasingly important role in supporting business-to-business and business-to-customer transactions, it is crucial for the participants in these transactions to...

PKA, PKC, and AKAP localization in and around the neuromuscular junction (2001)

Perkins, Guy A, Wang, Lin, Huang, Lily, Humphries, Kenneth, Yao, Virginia J, Martone, Maryann, ...

Abstract Background One mechanism that directs the action of the second messengers, cAMP and diacylglycerol, is the compartmentalization of protein kinase A (PKA) and protein kinase C (PKC). A-kinase...

Prediction of muscle activation from EMG signals using a neural network model /--by Lin Wang. (2001)

Wang, Lin.

Principal faculty adviser: Thomas S. Buchanan, Dept. of Mechanical Engineering.

Effect of auditory modeling on a swimming skill learning / (2001)

Wang, Lin.

Thesis (M.A.)--University of Northern Iowa, 2001.

Mechanistic Studies of the Palladium-Catalyzed Copolymerization of Ethylene and alpha-Olefins with Methyl Acrylate (1998)

Mecking, Stefan, Johnson, Lynda K., Wang, Lin, Brookhart, Maurice

Mechanistic aspects of palladium-catalyzed insertion copolymerizations of ethylene and α-olefins with methyl acrylate to give high molar mass polymers are described. Complexes...

Bimodal opioid signal transduction and its adaptation to chronic morphine treatment /--by Lin Wang. (1997)

Wang, Lin.

Submitted to the faculty of the School of Graduate Studies, State University of New York, Health Science Center at Brooklyn in partial fulfillment of the requirements for the Degree of Doctor of...

Feasibility study of bovine embryo microlabeling / (1996)

Wang, Lin.

Thesis (M.S. in Biomedical Engineering)--Louisiana Tech University, May 1996.

Quantitative DNA fiber mapping (1995)

Weler, H-U.G., Wang, Lin, Mullikin, J.C., Zhu, Y., Cheng, J-F., Greulich, K.M., ...

The assembly of sequence ready, high-resolution physical maps and construction of minimally overlapping contigs for the human as well as model genomes requires accurate determination of the extent of...

Chemistry of the hard-ligated organorhodium complexes /--by Lin Wang. (1993)

Wang, Lin.

Thesis (Ph. D.)--University of Southern California, 1993.

Cloning and mitochondrial localization of full-length D-AKAP2, a protein kinase A anchoring protein

Wang, Lin, Sunahara, Roger K., Krumins, Andrejs, Perkins, Guy, Crochiere, Marsha L., Mackey, Mason, ...

Differential compartmentalization of signaling molecules in cells and tissues is being recognized as an important mechanism for regulating the specificity of signal transduction pathways. A kinase...

Influence of the period-dependent circadian clock on diurnal, circadian, and aperiodic gene expression in Drosophila melanogaster

Lin, Yiing, Han, Mei, Shimada, Brian, Wang, Lin, Gibler, Therese M., Amarakone, Aloka, ...

We measured daily gene expression in heads of control and period mutant Drosophila by using oligonucleotide microarrays. In control flies, 72 genes showed diurnal rhythms in light-dark cycles; 22 of...

Distinct But Conserved Functions for Two Chloroplastic NADP-Malic Enzyme Isoforms in C3 and C4 Flaveria Species1

Lai, Lien B., Wang, Lin, Nelson, Timothy M.

In the most common C4 pathway for carbon fixation, an NADP-malic enzyme (NADP-ME) decarboxylates malate in the chloroplasts of bundle sheath cells. Isoforms of plastidic NADP-ME are encoded by two...

The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type II

Wang, Lin, Soroka, Carol J., Boyer, James L.

PFIC II is a subtype of progressive familial intrahepatic cholestasis (PFIC) that is associated with mutations in the ABCB11 gene encoding the bile salt export pump (BSEP). However it is not known...

The role of the LDL receptor in apolipoprotein B secretion

Twisk, Jaap, Gillian-Daniel, Donald L., Tebon, Angie, Wang, Lin, Barrett, P. Hugh R., Attie, Alan D.

Familial hypercholesterolemia is caused by mutations in the LDL receptor gene (Ldlr). Elevated plasma LDL levels result from slower LDL catabolism and a paradoxical lipoprotein overproduction. We...

Collagen α1(I) Gene (COL1A1) Is Repressed by RFX Family*

Sengupta, Pritam, Xu, Yong, Wang, Lin, Widom, Russell, Smith, Barbara D.

Collagen type I is composed of three polypeptide chains transcribed from two separate genes (COL1A1 and COL1A2) with different promoters requiring coordinate regulation. Our recent publications,...

Interferon-γ Induces Major Histocompatibility Class II Transactivator (CIITA) That Mediates Collagen Repression and Major Histocompatibility Class II Activation by Human Aortic Smooth Muscle Cells

Butticè, Giovanna, Miller, Janice, Wang, Lin, Smith, Barbara D.

Chronic inflammation in atherosclerosis is responsible for plaque instability through alterations in extracellular matrix. Previously, we demonstrated that major histocompatibility class II (MHC II)...

Multi-stage ponds-wetlands ecosystem for effective wastewater treatment*

Peng, Jian-feng, Wang, Bao-zhen, Wang, Lin

The performance of the Dongying multi-stage ponds-wetlands ecosystem was investigated in this work. Study of the removal of different pollutants (BOD5, COD, SS, TP, TN, NH3-N, etc.) in different...

Polymorphism in Maternal LRP8 Gene Is Associated with Fetal Growth

Wang, Lin, Wang, Xiaobin, Laird, Nan, Zuckerman, Barry, Stubblefield, Philip, Xu, Xin

Fetal growth restriction (FGR) affects >200,000 pregnancies in the United States annually and is associated with increased perinatal mortality and morbidity, as well as poorer long-term health for...

Cloning and mitochondrial localization of full-length D-AKAP2, a protein kinase A anchoring protein

Wang, Lin, Sunahara, Roger K., Krumins, Andrejs, Perkins, Guy, Crochiere, Marsha L., Mackey, Mason, ...

Differential compartmentalization of signaling molecules in cells and tissues is being recognized as an important mechanism for regulating the specificity of signal transduction pathways. A kinase...

Influence of the period-dependent circadian clock on diurnal, circadian, and aperiodic gene expression in Drosophila melanogaster

Lin, Yiing, Han, Mei, Shimada, Brian, Wang, Lin, Gibler, Therese M., Amarakone, Aloka, ...

We measured daily gene expression in heads of control and period mutant Drosophila by using oligonucleotide microarrays. In control flies, 72 genes showed diurnal rhythms in light-dark cycles; 22 of...

Distinct But Conserved Functions for Two Chloroplastic NADP-Malic Enzyme Isoforms in C3 and C4 Flaveria Species1

Lai, Lien B., Wang, Lin, Nelson, Timothy M.

In the most common C4 pathway for carbon fixation, an NADP-malic enzyme (NADP-ME) decarboxylates malate in the chloroplasts of bundle sheath cells. Isoforms of plastidic NADP-ME are encoded by two...

The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type II

Wang, Lin, Soroka, Carol J., Boyer, James L.

PFIC II is a subtype of progressive familial intrahepatic cholestasis (PFIC) that is associated with mutations in the ABCB11 gene encoding the bile salt export pump (BSEP). However it is not known...

The role of the LDL receptor in apolipoprotein B secretion

Twisk, Jaap, Gillian-Daniel, Donald L., Tebon, Angie, Wang, Lin, Barrett, P. Hugh R., Attie, Alan D.

Familial hypercholesterolemia is caused by mutations in the LDL receptor gene (Ldlr). Elevated plasma LDL levels result from slower LDL catabolism and a paradoxical lipoprotein overproduction. We...

Multi-stage ponds-wetlands ecosystem for effective wastewater treatment*

Peng, Jian-feng, Wang, Bao-zhen, Wang, Lin

The performance of the Dongying multi-stage ponds-wetlands ecosystem was investigated in this work. Study of the removal of different pollutants (BOD5, COD, SS, TP, TN, NH3-N, etc.) in different...

Polymorphism in Maternal LRP8 Gene Is Associated with Fetal Growth

Wang, Lin, Wang, Xiaobin, Laird, Nan, Zuckerman, Barry, Stubblefield, Philip, Xu, Xin

Fetal growth restriction (FGR) affects >200,000 pregnancies in the United States annually and is associated with increased perinatal mortality and morbidity, as well as poorer long-term health for...

An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery

Arteaga, Maria Francisca, Wang, Lin, Ravid, Tommer, Hochstrasser, Mark, Canessa, Cecilia M.

Serum- and glucocorticoid-induced kinase 1 (Sgk1) regulates many ion channels and transporters in epithelial cells and promotes cell survival under stress conditions. In this study we demonstrate...

Chronic Alcohol Consumption Accelerates Fibrosis in Response to Cerulein-Induced Pancreatitis in Rats

Deng, Xiaoying, Wang, Lin, Elm, Mary S., Gabazadeh, David, Diorio, Greg J., Eagon, Patricia K., ...

Alcohol consumption is a risk factor for chronic pancreatitis (CP), but the mechanism in humans remains obscure because prolonged alcohol consumption in most humans and animal models fails to produce...

Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase

Wang, Lin, Goodey, Nina M., Benkovic, Stephen J., Kohen, Amnon

One of the most intriguing questions in modern enzymology is whether enzyme dynamics evolved to enhance the catalyzed chemical transformation. In this study, dihydrofolate reductase, a small...

Synthesis and investigation of deoxyribonucleic acid/locked nucleic acid chimeric molecular beacons

Yang, Chaoyong James, Wang, Lin, Wu, Yanrong, Kim, Youngmi, Medley, Colin D., Lin, Hui, ...

To take full advantage of locked nucleic acid (LNA) based molecular beacons (LNA-MBs) for a variety of applications including analysis of complex samples and intracellular monitoring, we have...

Rbm15 Modulates Notch-Induced Transcriptional Activation and Affects Myeloid Differentiation▿ †

Ma, Xianyong, Renda, Matthew J., Wang, Lin, Cheng, Ee-chun, Niu, Chao, Morris, Stephan W., ...

RBM15 is the fusion partner with MKL in the t(1;22) translocation of acute megakaryoblastic leukemia. To understand the role of the RBM15-MKL1 fusion protein in leukemia, we must understand the...

The role of enzyme dynamics and tunnelling in catalysing hydride transfer: studies of distal mutants of dihydrofolate reductase

Wang, Lin, Goodey, Nina M, Benkovic, Stephen J, Kohen, Amnon

Residues M42 and G121 of Escherichia coli dihydrofolate reductase (ecDHFR) are on opposite sides of the catalytic centre (15 and 19 Å away from it, respectively). Theoretical studies have...

Crucial Role of the Interleukin 1 Receptor Family Member T1/St2 in T Helper Cell Type 2–Mediated Lung Mucosal Immune Responses

Coyle, Anthony J., Lloyd, Clare, Tian, Jane, Nguyen, Trang, Erikkson, Christina, Wang, Lin, ...

T1/ST2 is an orphan receptor of unknown function that is expressed on the surface of murine T helper cell type 2 (Th2), but not Th1 effector cells. In vitro blockade of T1/ST2 signaling with an...

Foreign reserves and the management of risk

Neil Humphries, Lin Wang

The risk management of New Zealand's foreign exchange reserves is discussed.

NH2-Terminal Targeting Motifs Direct Dual Specificity A-Kinase–anchoring Protein 1 (D-AKAP1) to Either Mitochondria or Endoplasmic Reticulum

Huang, Lily Jun-shen, Wang, Lin, Ma, Yuliang, Durick, Kyle, Perkins, Guy, Deerinck, Thomas J., ...

Subcellular localization directed by specific targeting motifs is an emerging theme for regulating signal transduction pathways. For cAMP-dependent protein kinase (PKA), this is achieved primarily by...

THE GINI COEFFICIENT'S APPLICATION TO GENERAL COMPLEX NETWORKS

HAI-BO HU, LIN WANG

The Gini coefficient, which was originally used in microeconomics to describe income inequality, is introduced into the research of general complex networks as a metric on the heterogeneity of...

SCALE-FREE EVOLVING NETWORKS WITH ACCELERATED ATTACHMENT

SEN QIN, GUANZHONG DAI, LIN WANG, MING FAN

A new evolving network based on the scale-free network of Barabási and Albert (BA) is studied, and the accelerated attachment of new edges is considered in its evolving process. The accelerated...

WHAT CONNECTION TOPOLOGY PROHIBIT CHAOS IN CONTINUOUS TIME NETWORKS?

XIAO-SONG YANG, QUAN YUAN, LIN WANG

In this paper, we are concerned with two interesting problems in the dynamics of neural networks. What connection topology will prohibit chaotic behavior in a continuous time neural network (NN). To...

Ph+/VE-cadherin+ identifies a stem cell–like population of acute lymphoblastic leukemia sustained by bone marrow niche cells

Wang, Lin, O'Leary, Heather, Fortney, James, Gibson, Laura F.

Although leukemic stem cells (LSCs) show a symbiotic relationship with bone marrow microenvironmental niches, the mechanism by which the marrow microenvironment contributes to self-renewal and...

Blockade of Notch Signaling in Tumor-Bearing Mice May Lead to Tumor Regression, Progression, or Metastasis, Depending on Tumor Cell Types1

Hu, Xing-Bin, Feng, Fan, Wang, Yao-Chun, Wang, Lin, He, Fei, Dou, Guo-Rui, ...

It has been reported that blocking Notch signaling in tumor-bearing mice results in abortive angiogenesis and tumor regression. However, given that Notch signaling influences numerous cellular...

Arabidopsis CaM Binding Protein CBP60g Contributes to MAMP-Induced SA Accumulation and Is Involved in Disease Resistance against Pseudomonas syringae

Wang, Lin, Tsuda, Kenichi, Sato, Masanao, Cohen, Jerry D., Katagiri, Fumiaki, Glazebrook, Jane

Salicylic acid (SA)-induced defense responses are important factors during effector triggered immunity and microbe-associated molecular pattern (MAMP)-induced immunity in plants. This article...

Protein Phosphatase 2A Is a Negative Regulator of Transforming Growth Factor-β1-induced TAK1 Activation in Mesangial Cells*

Kim, Sung Il, Kwak, Joon Hyeok, Wang, Lin, Choi, Mary E.

TAK1 (transforming growth factor (TGF)-β-activated kinase 1) is a serine/threonine kinase that is rapidly activated by TGF-β1 and plays a vital function in its signal transduction. Once TAK1 is...

Integrative Decomposition Procedure and Kappa Statistics for the Distinguished Single Molecular Network Construction and Analysis

Wang, Lin, Sun, Ying, Jiang, Minghu, Zheng, Xiguang

Our method concentrates on and constructs the distinguished single gene network. An integrated method was proposed based on linear programming and a decomposition procedure with integrated analysis...

Herbal compound 861 regulates mRNA expression of collagen synthesis- and degradation-related genes in human hepatic stellate cells

Wang, Lin, Wang, Bao-En, Wang, Jian, Xiao, Pei-Gen, Tan, Xue-Hai

AIM: To identify the role of herbal compound 861 (Cpd 861) in the regulation of mRNA expression of collagen synthesis- and degradation-related genes in human hepatic stellate cells (HSCs).

A Novel Flow Cytometric High Throughput Assay for a Systematic Study on Molecular Mechanisms Underlying T Cell Receptor-Mediated Integrin Activation

Kim, Kwangmi, Wang, Lin, Hwang, Inkyu

Lymphocyte function-associated antigen 1 (LFA-1), a member of β2-integrin family, exerts multiple roles in host T cell immunity and has been identified as a useful drug-development target for...

Preclinical evaluation of multiple species of PEGylated recombinant phenylalanine ammonia lyase for the treatment of phenylketonuria

Sarkissian, Christineh N., Gámez, Alejandra, Wang, Lin, Charbonneau, Marilyse, Fitzpatrick, Paul, Lemontt, Jeffrey F., ...

Phenylketonuria (PKU) is a metabolic disorder, in which loss of phenylalanine hydroxylase activity results in neurotoxic levels of phenylalanine. We used the Pahenu2/enu2 PKU mouse model in short-...

Change of intestinal mucosa barrier function in the progress of non-alcoholic steatohepatitis in rats

Li, Sheng, Wu, Wan-Chun, He, Chi-Yi, Han, Zhen, Jin, Dao-You, Wang, Lin

AIM: To explore the change of intestinal mucosa barrier function in the progress of non-alcoholic steatohepatitis (NASH) in rats.

Proline-Rich Tyrosine Kinase 2 Regulates Spreading and Migration of Eosinophils after β2-Integrin Adhesion

Zhu, Xiangdong, Boetticher, Evan, Wang, Lin, Duan, Yingli, Learoyd, Jonathan, Leff, Alan R.

We examined the role of proline-rich tyrosine kinase (Pyk) 2 in the spreading and migration of human blood eosinophils after β2-integrin ligation. Western blot analysis showed that Pyk2 was...

Role of transforming growth factor-beta signaling pathway in pathogenesis of benign biliary stricture

Geng, Zhi-Min, Zheng, Jian-Bao, Zhang, Xiao-Xue, Tao, Jie, Wang, Lin

AIM: To characterize the expression of members of the transforming growth factor-beta (TGF-β)/Smad/connective tissue growth factor (CTGF) signaling pathway in the tissue of benign biliary stricture,...

Formation of nanoparticles of blue haze enhanced by anthropogenic pollution

Zhang, Renyi, Wang, Lin, Khalizov, Alexei F., Zhao, Jun, Zheng, Jun, McGraw, Robert L., ...

The molecular processes leading to formation of nanoparticles of blue haze over forested areas are highly complex and not fully understood. We show that the interaction between biogenic organic acids...

Notch-RBP-J Signaling Regulates the Mobilization and Function of Endothelial Progenitor Cells by Dynamic Modulation of CXCR4 Expression in Mice

Wang, Lin, Wang, Yao-Chun, Hu, Xing-Bin, Zhang, Bing-Fang, Dou, Guo-Rui, He, Fei, ...

Bone marrow (BM)-derived endothelial progenitor cells (EPC) have therapeutic potentials in promoting tissue regeneration, but how these cells are modulated in vivo has been elusive. Here, we report...

Acute Inhibition of Selected Membrane-Proximal Mouse T Cell Receptor Signaling by Mitochondrial Antagonists

Kim, Kwangmi, Wang, Lin, Hwang, Inkyu

T cells absorb nanometric membrane vesicles, prepared from plasma membrane of antigen presenting cells, via dual receptor/ligand interactions of T cell receptor (TCR) with cognate peptide/major...