Linda K. McDougal

Detection of Tn917-Like Sequences within a Tn916-like Conjugative Transposon (Tn3872) in Erythromycin-Resistant Isolates of Streptococcus pneumoniae

McDougal, Linda K., Tenover, Fred C., Lee, Linda N., Rasheed, J. Kamile, Patterson, Jan E., Jorgensen, James H., ...

A series of macrolide-lincosamide-streptogramin B (MLS)-resistant pneumococcal isolates of a variety of serotypes was examined and was found to contain Tn917-like elements by DNA-DNA hybridization....

Characterization of Erythromycin-Resistant Isolates of Staphylococcus aureus Recovered in the United States from 1958 through 1969

Nicola, Federico G., McDougal, Linda K., Biddle, James W., Tenover, Fred C.

We tested 16 erythromycin-resistant clinical isolates of S. aureus, recovered from patients hospitalized in the United States from 1958 to 1969, for the presence of ermA, ermB, and ermC by using PCR....

Pulsed-Field Gel Electrophoresis Typing of Oxacillin-Resistant Staphylococcus aureus Isolates from the United States: Establishing a National Database

McDougal, Linda K., Steward, Christine D., Killgore, George E., Chaitram, Jasmine M., McAllister, Sigrid K., Tenover, Fred C.

Oxacillin-resistant Staphylococcus aureus (ORSA) is a virulent pathogen responsible for both health care-associated and community onset disease. We used SmaI-digested genomic DNA separated by...

Vancomycin-Resistant Staphylococcus aureus Isolate from a Patient in Pennsylvania

Tenover, Fred C., Weigel, Linda M., Appelbaum, Peter C., McDougal, Linda K., Chaitram, Jasmine, McAllister, Sigrid, ...

A vancomycin-resistant Staphylococcus aureus (VRSA) isolate was obtained from a patient in Pennsylvania in September 2002. Species identification was confirmed by standard biochemical tests and...

Testing for Induction of Clindamycin Resistance in Erythromycin-Resistant Isolates of Staphylococcus aureus

Steward, Christine D., Raney, Patti M., Morrell, Allison K., Williams, Portia P., McDougal, Linda K., Jevitt, Laura, ...

Disk diffusion and broth microdilution (BMD) were used to perform clindamycin (CLI) induction testing on 128 selected nonduplicate isolates of Staphylococcus aureus. Disk diffusion testing involved...

Characterization of a Strain of Community-Associated Methicillin-Resistant Staphylococcus aureus Widely Disseminated in the United States†

Tenover, Fred C., McDougal, Linda K., Goering, Richard V., Killgore, George, Projan, Steven J., Patel, Jean B., ...

A highly stable strain of Staphylococcus aureus with a pulsed-field gel electrophoresis type of USA300 and multilocus sequence type 8 has been isolated from patients residing in diverse geographic...

Detection of Tn917-Like Sequences within a Tn916-like Conjugative Transposon (Tn3872) in Erythromycin-Resistant Isolates of Streptococcus pneumoniae

McDougal, Linda K., Tenover, Fred C., Lee, Linda N., Rasheed, J. Kamile, Patterson, Jan E., Jorgensen, James H., ...

A series of macrolide-lincosamide-streptogramin B (MLS)-resistant pneumococcal isolates of a variety of serotypes was examined and was found to contain Tn917-like elements by DNA-DNA hybridization....

Characterization of Erythromycin-Resistant Isolates of Staphylococcus aureus Recovered in the United States from 1958 through 1969

Nicola, Federico G., McDougal, Linda K., Biddle, James W., Tenover, Fred C.

We tested 16 erythromycin-resistant clinical isolates of S. aureus, recovered from patients hospitalized in the United States from 1958 to 1969, for the presence of ermA, ermB, and ermC by using PCR....

Pulsed-Field Gel Electrophoresis Typing of Oxacillin-Resistant Staphylococcus aureus Isolates from the United States: Establishing a National Database

McDougal, Linda K., Steward, Christine D., Killgore, George E., Chaitram, Jasmine M., McAllister, Sigrid K., Tenover, Fred C.

Oxacillin-resistant Staphylococcus aureus (ORSA) is a virulent pathogen responsible for both health care-associated and community onset disease. We used SmaI-digested genomic DNA separated by...

Vancomycin-Resistant Staphylococcus aureus Isolate from a Patient in Pennsylvania

Tenover, Fred C., Weigel, Linda M., Appelbaum, Peter C., McDougal, Linda K., Chaitram, Jasmine, McAllister, Sigrid, ...

A vancomycin-resistant Staphylococcus aureus (VRSA) isolate was obtained from a patient in Pennsylvania in September 2002. Species identification was confirmed by standard biochemical tests and...

Testing for Induction of Clindamycin Resistance in Erythromycin-Resistant Isolates of Staphylococcus aureus

Steward, Christine D., Raney, Patti M., Morrell, Allison K., Williams, Portia P., McDougal, Linda K., Jevitt, Laura, ...

Disk diffusion and broth microdilution (BMD) were used to perform clindamycin (CLI) induction testing on 128 selected nonduplicate isolates of Staphylococcus aureus. Disk diffusion testing involved...

Characterization of a Strain of Community-Associated Methicillin-Resistant Staphylococcus aureus Widely Disseminated in the United States†

Tenover, Fred C., McDougal, Linda K., Goering, Richard V., Killgore, George, Projan, Steven J., Patel, Jean B., ...

A highly stable strain of Staphylococcus aureus with a pulsed-field gel electrophoresis type of USA300 and multilocus sequence type 8 has been isolated from patients residing in diverse geographic...

High-Level Vancomycin-Resistant Staphylococcus aureus Isolates Associated with a Polymicrobial Biofilm▿

Weigel, Linda M., Donlan, Rodney M., Shin, Dong Hyeon, Jensen, Bette, Clark, Nancye C., McDougal, Linda K., ...

Glycopeptides such as vancomycin are the treatment of choice for infections due to methicillin-resistant Staphylococcus aureus. This study describes the identification of high-level...

Rapid Multiplex PCR Assay for Identification of USA300 Community-Associated Methicillin-Resistant Staphylococcus aureus Isolates▿

Bonnstetter, Kristin K., Wolter, Daniel J., Tenover, Fred C., McDougal, Linda K., Goering, Richard V.

Recent reports have noted a discernible increase in the number of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections in patients without traditional risk factors....

High Frequencies of Clindamycin and Tetracycline Resistance in Methicillin-Resistant Staphylococcus aureus Pulsed-Field Type USA300 Isolates Collected at a Boston Ambulatory Health Center▿

Han, Linda L., McDougal, Linda K., Gorwitz, Rachel J., Mayer, Kenneth H., Patel, Jean B., Sennott, Janet M., ...

Individual or multiple resistance to clindamycin, tetracycline, erythromycin, levofloxacin, or mupirocin was detected in a large proportion of methicillin-resistant Staphylococcus aureus pulsed-field...

Epidemiologic Distribution of the Arginine Catabolic Mobile Element among Selected Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Isolates▿

Goering, Richard V., McDougal, Linda K., Fosheim, Greg E., Bonnstetter, Kristin K., Wolter, Daniel J., Tenover, Fred C.

We tested 214 Staphylococcus aureus isolates for the arcA locus of the arginine catabolic mobile element (ACME). All USA300 SCCmec IVa isolates, but no isolates containing other SCCmec subtypes, were...

Multiple-Locus Variable-Number Tandem-Repeat Assay Analysis of Methicillin-Resistant Staphylococcus aureus Strains▿

Tenover, Fred C., Vaughn, Rebekah R., McDougal, Linda K., Fosheim, Gregory E., McGowan, John E.

Our objective was to determine if a multiple-locus variable-number tandem-repeat assay (MLVA) for Staphylococcus aureus could predict pulsed-field gel electrophoresis (PFGE) types (i.e., USA types),...

Detection of Inducible Clindamycin Resistance in Staphylococci by Broth Microdilution Using Erythromycin-Clindamycin Combination Wells▿

Swenson, Jana M., Brasso, William B., Ferraro, Mary Jane, Hardy, Dwight J., Knapp, Cynthia C., McDougal, Linda K., ...

A study conducted by 11 laboratories investigated the ability of four combinations of erythromycin (ERY) and clindamycin (CC) (ERY and CC at 4 and 0.5, 6 and 1, 8 and 1.5, and 0.5 and 2 μg/ml) in a...

Vancomycin-Resistant Staphylococcus aureus Isolates Associated with Inc18-Like vanA Plasmids in Michigan▿

Zhu, Wenming, Clark, Nancye C., McDougal, Linda K., Hageman, Jeffery, McDonald, L. Clifford, Patel, Jean B.

Five of the seven cases of vancomycin-resistant Staphylococcus aureus (VRSA) infection identified to date have occurred in southeastern Michigan. VRSA isolates from the four most recent cases (all...

Community Strains of Methicillin-Resistant Staphylococcus aureus as Potential Cause of Healthcare-associated Infections, Uruguay, 2002–2004

Benoit, Stephen R., Estivariz, Concepción, Mogdasy, Cristina, Pedreira, Walter, Galiana, Antonio, Galiana, Alvaro, ...

Community-associated MRSA appears to be replacing healthcare-associated MRSA strain types in at least 1 facility and is a cause of healthcare-onset infections.

Characterization of Staphylococcus aureus Isolates from Nasal Cultures Collected from Individuals in the United States in 2001 to 2004▿

Tenover, Fred C., McAllister, Sigrid, Fosheim, Gregory, McDougal, Linda K., Carey, Roberta B., Limbago, Brandi, ...

This study characterizes methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA) isolates recovered from nasal cultures of noninstitutionalized individuals in...