118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects (2009)
Shaw, Gary M, Lu, Wei, Zhu, Huiping, Yang, Wei, Briggs, Farren BS, Carmichael, Suzan L, ...
Abstract Background Folic acid taken in early pregnancy reduces risks for delivering offspring with several congenital anomalies. The mechanism by which folic acid reduces risk is unknown....
Mapping Multiple Sclerosis Susceptibility to the HLA-DR Locus in African Americans (2008)
Jorge R. Oksenberg, Lisa F. Barcellos, Sergio E. Baranzini, Teodorica L. Bugawan, Omar Khan, ...
An underlying complex genetic susceptibility exists in multiple sclerosis (MS), and an association with the HLA-DRB1*1501-DQB1*0602 haplotype has been repeatedly demonstrated in high-risk (northern...
Aldrich, Melinda C., Selvin, Steve, Hansen, Helen M., Barcellos, Lisa F., Wrensch, Margaret R., Sison, Jennette D., ...
A variety of methods are available for estimating genetic admixture proportions in populations; however, few investigators have conducted detailed comparisons using empirical data. The authors...
A second major histocompatibility complex susceptibility locus for multiple sclerosis (2007)
Gregory, Simon G, Barcellos, Lisa F, Walton, Amie, ...
Objective: Variation in the major histocompatibility complex (MHC) on chromosome 6p21 is known to influence susceptibility to multiple sclerosis with the strongest effect originating from the...
Traherne, James A., Barcellos, Lisa F., Sawcer, Stephen J., Compston, Alastair, Ramsay, Patricia P., Hauser, Stephen L., ...
The major histocompatibility complex human leukocyte antigen (HLA)-DRB1*15 (DR2) haplotype is strongly associated with risk of multiple sclerosis (MS). The primary susceptibility has been localized...
Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis (2006)
Barcellos, Lisa F., Sawcer, Stephen, Ramsay, Patricia P., Baranzini, Sergio E., Thomson, Glenys, Briggs, Farren, ...
Variation in major histocompatibility complex (MHC) genes on chromosome 6p21.3, specifically the HLA-DR2 or DRB1*1501-DQB1*0602 extended haplotype, confers risk for multiple sclerosis (MS). Previous...
Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis (2006)
Barcellos, Lisa F., Sawcer, Stephen, Ramsay, Patricia P., Baranzini, Sergio E., Thomson, Glenys, Briggs, Farren, ...
Variation in major histocompatibility complex genes on chromosome 6p21.3, specifically the human leukocyte antigen HLA-DR2 or DRB1*1501-DQB1*0602 extended haplotype, confers risk for multiple...
Traherne, James A., Barcellos, Lisa F., Sawcer, Stephen J., Compston, D. Alastair S., Ramsay, Patricia P., Hauser, Stephen L., ...
The major histocompatibility complex HLA-DRB1*15 (DR2) haplotype is strongly associated with risk of multiple sclerosis. The primary susceptibility has been localised to only a ∼200 kb region...
Multiple susceptibility loci for multiple sclerosis (2002)
Haines, Jonathan L., Bradford, Yuki, Garcia, Melissa E., Reed, Allison D., Neumeister, Elizabeth, ...
Multiple sclerosis (MS) is a common and frequently disabling autoimmune disorder mediated by autoaggressive T cells and autoantibodies that target central nervous system myelin. While numerous...
Schmidt, Silke, Barcellos, Lisa F., DeSombre, Karen, Rimmler, Jacqueline B., Lincoln, Robin R., Bucher, Patricia, ...
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system, with a complex etiology that includes a strong genetic component. The contribution of the major...
Mapping Multiple Sclerosis Susceptibility to the HLA-DR Locus in African Americans
Oksenberg, Jorge R., Barcellos, Lisa F., Cree, Bruce A. C., Baranzini, Sergio E., Bugawan, Teodorica L., Khan, Omar, ...
An underlying complex genetic susceptibility exists in multiple sclerosis (MS), and an association with the HLA-DRB1*1501-DQB1*0602 haplotype has been repeatedly demonstrated in high-risk (northern...
Begovich, Ann B., Caillier, Stacy J., Alexander, Heather C., Penko, Joanne M., Hauser, Stephen L., Barcellos, Lisa F., ...
118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects
Shaw, Gary M, Lu, Wei, Zhu, Huiping, Yang, Wei, Briggs, Farren BS, Carmichael, Suzan L, ...
A second major histocompatibility complex susceptibility locus for multiple sclerosis
Yeo, Tai Wai, De Jager, Philip L, Gregory, Simon G, Barcellos, Lisa F, Walton, Amie, Goris, An, ...
Barcellos, Lisa F., May, Suzanne L., Ramsay, Patricia P., Quach, Hong L., Lane, Julie A., Nititham, Joanne, ...
A substantial genetic contribution to systemic lupus erythematosus (SLE) risk is conferred by major histocompatibility complex (MHC) gene(s) on chromosome 6p21. Previous studies in SLE have lacked...
Aldrich, Melinda C., Selvin, Steve, Hansen, Helen M., Barcellos, Lisa F., Wrensch, Margaret R., Sison, Jennette D., ...
A variety of methods are available for estimating genetic admixture proportions in populations; however, few investigators have conducted detailed comparisons using empirical data. The authors...