Crystallization of the Protective Antigen Protein of Bacillus anthracis (2003)
Allured, Viloya S., Case, Lisa M., Leppla, Stephen H., McKay, David B.
The protective antigen protein, one of the three separate proteins constituting the exotoxin system of Bacillus anthracis, has been crystallized in a form suitable for high resolution structural...
The Role of Metallothionein in the Pathogenesis of Acute Lung Injury
Wesselkamper, Scott C., McDowell, Susan A., Medvedovic, Mario, Dalton, Timothy P., Deshmukh, Hitesh S., Sartor, Maureen A., ...
Often fatal, acute lung injury has a complicated etiology. Previous studies from our laboratory in mice have demonstrated that survival during acute lung injury is a complex trait governed by...
Acrolein-Activated Matrix Metalloproteinase 9 Contributes to Persistent Mucin Production
Deshmukh, Hitesh S., Shaver, Colleen, Case, Lisa M., Dietsch, Maggie, Wesselkamper, Scott C., Hardie, William D., ...
Chronic obstructive pulmonary disease (COPD), a global public health problem, is characterized by progressive difficulty in breathing, with increased mucin production, especially in the small...
Wesselkamper, Scott C., Case, Lisa M., Henning, Lisa N., Borchers, Michael T., Tichelaar, Jay W., Mason, John M., ...
Rationale: Acute lung injury can occur from multiple causes, resulting in high mortality. The pathophysiology of nickel-induced acute lung injury in mice is remarkably complex, and the molecular...