Lorna A. Ringwood

Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control

Huang, Zhi, Shiva, Sruti, Kim-Shapiro, Daniel B., Patel, Rakesh P., Ringwood, Lorna A., Irby, Cynthia E., ...

Hypoxic vasodilation is a fundamental, highly conserved physiological response that requires oxygen and/or pH sensing coupled to vasodilation. While this process was first characterized more than 80...

Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control

Huang, Zhi, Shiva, Sruti, Kim-Shapiro, Daniel B., Patel, Rakesh P., Ringwood, Lorna A., Irby, Cynthia E., ...

Hypoxic vasodilation is a fundamental, highly conserved physiological response that requires oxygen and/or pH sensing coupled to vasodilation. While this process was first characterized more than 80...

Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

Shiva, Sruti, Sack, Michael N., Greer, James J., Duranski, Mark, Ringwood, Lorna A., Burwell, Lindsay, ...

Nitrite (NO2−) is an intrinsic signaling molecule that is reduced to NO during ischemia and limits apoptosis and cytotoxicity at reperfusion in the mammalian heart, liver, and brain. Although the...