Louis Hermo

Dysregulation of WNT/CTNNB1 and PI3K/AKT signaling in testicular stromal cells causes granulosa cell tumor of the testis (2009)

Boyer, Alexandre, Paquet, Marilène, Laguë, Marie-Noëlle, Hermo, Louis, Boerboom, Derek

Synergistic effects of dysregulation of the WNT/CTNNB1 and phosphatidylinositol 3-kinase (PI3K)/AKT pathways are thought to be important for the development and progression of many forms of cancer,...

Structural and Functional Modifications of Sertoli Cells in the Testis of Adult Follicle-Stimulating Hormone Receptor Knockout Mice1 (2004)

Amit Grover, M. Ram Sairam, Charles E. Smith, Louis Hermo

Follicle stimulating hormone (FSH) plays important roles during testicular development and in the maintenance of spermatogenesis in the adult. However, the cellular events or pathways that FSH...

Expression and Localization of Cathepsin K In Adult Rat Sertoli Cells1 (2004)

Matthew D. Anway, William W. Wright, Barry R. Zirkin, Nadine Korah, John S. Mort, Louis Hermo

The cathepsins are a family of cysteine proteases that have been broadly implicated in proteolytic processes during cell growth, cell development, and normal adult cellular function. Cathepsin L is a...

Acquisition of Arylsulfatase A onto the Mouse Sperm Surface During Epididymal Transit1 (2003)

Wattana Weerachatyanukul, Hongbin Xu, Araya Anupriwan, Euridice Carmona, Michael Wade, Louis Hermo, ...

Arylsulfatase A (AS-A) is localized to the sperm surface and participates in sperm-zona pellucida binding. We investigated how AS-A, usually known as an acrosomal enzyme, trafficked to the sperm...

Fusogenic Domains of Golgi Membranes Are Sequestered into Specialized Regions of the Stack that Can Be Released by Mechanical Fragmentation

Dominguez, Michel, Fazel, Ali, Dahan, Sophie, Lovell, Jacque, Hermo, Louis, Claude, Alejandro, ...

A well-characterized cell-free assay that reconstitutes Golgi transport is shown to require physically fragmented Golgi fractions for maximal activity. A Golgi fraction containing large, highly...