Louise Veronica O'Keefe

Common chromosomal fragile sites and cancer: Focus on FRA16D (2006)

O'Keefe, Louise Veronica, Richards, Robert Ian

A growing body of experimental evidence supports the view that certain human chromosomal fragile sites have roles to play in cancer. The principle lines of evidence are at the level of mutation...

Common chromosomal fragile sites and cancer: Focus on FRA16D (2006)

O'Keefe, Louise Veronica, Richards, Robert Ian

A growing body of experimental evidence supports the view that certain human chromosomal fragile sites have roles to play in cancer. The principle lines of evidence are at the level of mutation...

The pathogenic agent in Drosophila models of 'polyglutamine' diseases (2005)

McLeod, Catherine Jean, O'Keefe, Louise Veronica, Richards, Robert Ian

A substantial body of evidence supports the identity of polyglutamine as the pathogenic agent in a variety of human neurodegenerative disorders where the mutation is an expanded CAG repeat. However,...

FRA16D common chromosomal fragile site oxido-reductase (FOR/WWOX) protects against the effects of ionizing radiation in Drosophila (2005)

O'Keefe, Louise Veronica, Liu, Yinghong, Perkins, A. J., Dayan, Sonia, Saint, Robert Bryce, Richards, Robert Ian

Fragile sites are chromosomal structures that have been proposed to have a determining role in cancer-associated DNA instability. The human WWOX gene spans the FRA16D chromosomal fragile site, the...

The pathogenic agent in Drosophila models of 'polyglutamine' diseases (2005)

McLeod, Catherine Jean, O'Keefe, Louise Veronica, Richards, Robert Ian

A substantial body of evidence supports the identity of polyglutamine as the pathogenic agent in a variety of human neurodegenerative disorders where the mutation is an expanded CAG repeat. However,...

FRA16D common chromosomal fragile site oxido-reductase (FOR/WWOX) protects against the effects of ionizing radiation in Drosophila (2005)

O'Keefe, Louise Veronica, Liu, Yinghong, Perkins, A. J., Dayan, Sonia, Saint, Robert Bryce, Richards, Robert Ian

Fragile sites are chromosomal structures that have been proposed to have a determining role in cancer-associated DNA instability. The human WWOX gene spans the FRA16D chromosomal fragile site, the...