Predicting the binding preference of transcription factors to individual DNA k-mers (2009)
Alleyne, Trevis M., Peña-Castillo, Lourdes, Badis, Gwenael, Talukder, Shaheynoor, Berger, Michael F., Gehrke, Andrew R., ...
Motivation: Recognition of specific DNA sequences is a central mechanism by which transcription factors (TFs) control gene expression. Many TF-binding preferences, however, are unknown or poorly...
Peña-Castillo, Lourdes, Tasan, Murat, Myers, Chad L, Lee, Hyunju, Joshi, Trupti, Zhang, Chao, ...
Abstract Background: Several years after sequencing the human genome and the mouse genome, much remains to be discovered about the functions of most human and mouse genes. Computational prediction of...
Lovegrove, Fiona E, Peña-Castillo, Lourdes, Mohammad, Naveed, Liles, W Conrad, Hughes, Timothy R, Kain, Kevin C
Abstract Background The development and outcome of cerebral malaria (CM) reflects a complex interplay between parasite-expressed virulence factors and host response to infection. The murine CM model,...
Lovegrove, Fiona E, Peña-Castillo, Lourdes, Mohammad, Naveed, Liles, W Conrad, Hughes, Timothy R, Kain, Kevin C
Lovegrove, Fiona E, Peña-Castillo, Lourdes, Mohammad, Naveed, Liles, W Conrad, Hughes, Timothy R, Kain, Kevin C
Why Are There Still Over 1000 Uncharacterized Yeast Genes?
Peña-Castillo, Lourdes, Hughes, Timothy R.
The yeast genetics community has embraced genomic biology, and there is a general understanding that obtaining a full encyclopedia of functions of the ∼6000 genes is a worthwhile goal. The yeast...
Lovegrove, Fiona E., Gharib, Sina A., Peña-Castillo, Lourdes, Patel, Samir N., Ruzinski, John T., Hughes, Timothy R., ...
Although acute lung injury (ALI) is a common complication of severe malaria, little is known about the underlying molecular basis of lung dysfunction. Animal models have provided powerful insights...
A critical assessment of Mus musculus gene function prediction using integrated genomic evidence
Peña-Castillo, Lourdes, Tasan, Murat, Myers, Chad L, Lee, Hyunju, Joshi, Trupti, Zhang, Chao, ...
Predicting the binding preference of transcription factors to individual DNA k-mers
Alleyne, Trevis M., Peña-Castillo, Lourdes, Badis, Gwenael, Talukder, Shaheynoor, Berger, Michael F., Gehrke, Andrew R., ...
Motivation: Recognition of specific DNA sequences is a central mechanism by which transcription factors (TFs) control gene expression. Many TF-binding preferences, however, are unknown or poorly...