Lu Chen

Publication List Details

Period

1995 - 2009

Number

96

Co-Authors

Efficient Collision Determination for Dynamic Scenes using Coherent Separating Axis (2009)

Lu Chen, Wei Hua, Zhong Ren, Hujun Bao

Abstract. We present an efficient algorithm for collision determination of dynamic objects undergoing rigid motion or general deformation. Our technique deals with triangulated models, and it...

(S)-Benzyl 2-amino-3-(4-hydroxyphenyl)propanoate (2009)

Shu-Na Luo, Lu Chen, Yu-Xing Gao, Peng-Xiang Xu, Yu-Fen Zhao

The title compound, C16H17NO3, adopts a folded conformation in the crystal structure. The crystal packing is stabilized by intermolecular O—H...O and N—H...O hydrogen-bonding...

Kazrin F is involved in apoptosis and interacts with BAX and ARC (2009)

Wang, Qiong, Liu, Min, Li, Xin, Chen, Lu, Tang, Hua

Kazrin has recently been identified as a functional protein that is involved in cell–cell junctions and in signal transduction. Here, we identified a new isoform, Kazrin F, which is 518 aa in...

Functional Genomic Analysis Reveals Cross-talk between Peroxisome Proliferator-activated Receptor � and Calcium Signaling in Human Colorectal Cancer Cells *□S (2008)

Craig R. Bush, Jennifer M. Havens, Brian M. Necela, Weidong Su, Lu Chen, Masahiro Yanagisawa, ...

and anchorage-independent growth and invasion through Matrigel-coated transwell membranes. We carried out a longitudinal two-class microarray analysis in which mRNA abundance was measured as a...

Processing of G4 DNA by Dna2 Helicase/nuclease and RPA provides insights into the mechanism of Dna2/RPA substrate recognition (2008)

Masuda-Sasa, Taro, Polaczek, Piotr, Peng, Xiao P., Chen, Lu, Campbell, Judith L.

The polyguanine-rich DNA sequences commonly found at telomeres and in rDNA arrays have been shown to assemble into structures known as G quadruplexes, or G4 DNA, stabilized by base-stacked G...

Characterization and functional analysis of yeast SNARE longin domains (2008)

Chen, Lu

Thesis (Ph.D.)--Hong Kong University of Science and Technology, 2008

Finding Frequent Closed Itemsets in Sliding Window in Linear Time (2008)

CHEN, Junbo, ZHOU, Bo, CHEN, Lu, WANG, Xinyu, DING, Yiqun

One of the most well-studied problems in data mining is computing the collection of frequent itemsets in large transactional databases. Since the introduction of the famous Apriori algorithm [14],...

Genetic variants in fibroblast growth factor receptor 2 (FGFR2) contribute to susceptibility of breast cancer in Chinese women (2008)

Liang, Jie, Chen, Peizhan, Hu, Zhibin, Zhou, Xiaoyi, Chen, Lu, Li, Mian, ...

Fibroblast growth factor receptor 2 (FGFR2) belongs to the FGFR family, which plays an important role in cell growth, invasiveness, motility and angiogenesis. In human breast cancer, expression of...

Parallel gene synthesis in a microfluidic device (2007)

Kong, David S., Carr, Peter A., Chen, Lu, Zhang, Shuguang, Jacobson, Joseph M.

The ability to synthesize custom de novo DNA constructs rapidly, accurately and inexpensively is highly desired by researchers, as synthetic genes and longer DNA constructs are enabling to numerous...

Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator (2007)

Stogios, Peter J., Chen, Lu, Privé, Gilbert G.

BTB-zinc finger (BTB-ZF) proteins are transcription regulators with roles in development, differentiation, and oncogenesis. In these proteins, the BTB domain (also known as the POZ domain) is a...

Reliability, Effect Size, and Responsiveness and Intraclass Correlation of Health Status Measures Used in Randomized and Cluster-Randomized Trials (2006)

Diehr, Paula, Chen, Lu, Patrick, Donald L., Feng, Ziding, Yasui, Yutaka

Background: New health status instruments are described by psychometric properties, such as Reliability, Effect Size, and Responsiveness. For cluster-randomized trials, another important statistic is...

Reliability, Effect Size, and Responsiveness and Intraclass Correlation of Health Status Measures Used in Randomized and Cluster-Randomized Trials (2006)

Diehr, Paula, Chen, Lu, Patrick, Donald L., Feng, Ziding, Yasui, Yutaka

Background: New health status instruments are described by psychometric properties, such as Reliability, Effect Size, and Responsiveness. For cluster-randomized trials, another important statistic is...

Reliability, Effect Size, and Responsiveness and Intraclass Correlation of Health Status Measures Used in Randomized and Cluster-Randomized Trials (2006)

Diehr, Paula, Chen, Lu, Patrick, Donald L., Feng, Ziding, Yasui, Yutaka

Background: New health status instruments are described by psychometric properties, such as Reliability, Effect Size, and Responsiveness. For cluster-randomized trials, another important statistic is...

Reliability, Effect Size, and Responsiveness and Intraclass Correlation of Health Status Measures Used in Randomized and Cluster-Randomized Trials (2006)

Diehr, Paula, Chen, Lu, Patrick, Donald L., Feng, Ziding, Yasui, Yutaka

Background: New health status instruments are described by psychometric properties, such as Reliability, Effect Size, and Responsiveness. For cluster-randomized trials, another important statistic is...

Cardiac implications for the use of beta(2)-adrenoceptor agonists for the management of muscle wasting (2006)

Molenaar, Peter, Chen, Lu, Parsonage, William A.

There are proposals for the implementation of beta(2)-adrenoceptor agonists for the management of muscle wasting diseases. The idea has been initiated by studies in animal models which show that...

Cardiac implications for the use of beta(2)-adrenoceptor agonists for the management of muscle wasting (2006)

Molenaar, Peter, Chen, Lu, Parsonage, William A.

There are proposals for the implementation of beta(2)-adrenoceptor agonists for the management of muscle wasting diseases. The idea has been initiated by studies in animal models which show that...

Crystal structures of saposins A and C (2006)

Ahn, Victoria E., Leyko, Paul, Alattia, Jean-René, Chen, Lu, Privé, Gilbert G.

Saposins A and C are sphingolipid activator proteins required for the lysosomal breakdown of galactosylceramide and glucosylceramide, respectively. The saposins interact with lipids, leading to an...

Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator (2006)

Stogios, Peter J., Chen, Lu, Privé, Gilbert G.

BTB-zinc finger (BTB-ZF) proteins are transcription regulators with roles in development, differentiation, and oncogenesis. In these proteins, the BTB domain (also known as the POZ domain) is a...

Crystal structures of saposins A and C (2006)

Ahn, Victoria E., Leyko, Paul, Alattia, Jean-René, Chen, Lu, Privé, Gilbert G.

Saposins A and C are sphingolipid activator proteins required for the lysosomal breakdown of galactosylceramide and glucosylceramide, respectively. The saposins interact with lipids, leading to an...

Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator (2006)

Stogios, Peter J., Chen, Lu, Privé, Gilbert G.

BTB-zinc finger (BTB-ZF) proteins are transcription regulators with roles in development, differentiation, and oncogenesis. In these proteins, the BTB domain (also known as the POZ domain) is a...

Does Information Undermine Brand? Information Intermediary Use and Preference for Branded Web Retailers (2003)

Joel Waldfogel The, Lu Chen

Investments in advertising to create brands provide one method for vendors to convince potential customers that vendors will deliver as promised. Alternatively, third-party information on whether...

Improving ordering semantics in group communications / (2001)

Chen, Lu.

Thesis (M.S.)--Kansas State University, 2002.

Circuit design of a high speed and low power CMOS continuous-time current comparator (2001)

Lu Chen, Bingxue Shi, Chun Lu

Abstract. Current comparator is a fundamental component of current-mode analog integrated circuits. A novel high-performance continuous-time CMOS current comparator is proposed in this paper, which...

Inhibitory and bioassay response of nitrifying bacteria (1998)

Chen, Lu

Bacterial bioassay strategies have recently drawn an escalating level of technical interest given their expected ease of use, response sensitivity, and cost effectiveness. Four strategies are cited...

Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice (1997)

Kim, Jeansok J., Shih, Jean C., Chen, Kevin, Chen, Lu, Bao, Shaowen, Maren, Stephen, ...

Mice deficient in monoamine oxidase A (MAOA), an enzyme that metabolizes monoamines such as norepinephrine and serotonin, have elevated norepinephrine and serotonin levels in the frontal cortex,...

Computerized evaluation of parameters for HEMT DC and microwave S parameter models (1995)

Chen, Lu

Computerized evaluation of parameters for HEMT DC and microwave S parameter models

Computerized evaluation of parameters for HEMT DC and microwave S parameter models (1995)

Chen, Lu

Computerized evaluation of parameters for HEMT DC and microwave S parameter models

Impaired cerebellar synapse maturation in waggler, a mutant mouse with a disrupted neuronal calcium channel γ subunit

Chen, Lu, Bao, Shaowen, Qiao, Xiaoxi, Thompson, Richard F.

The waggler, a neurological mutant mouse with a disrupted putative neuronal Ca2+ channel γ subunit, exhibits a cerebellar granule cell-specific brain-derived neurotrophic factor deficit, severe...

Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice

Kim, Jeansok J., Shih, Jean C., Chen, Kevin, Chen, Lu, Bao, Shaowen, Maren, Stephen, ...

Mice deficient in monoamine oxidase A (MAOA), an enzyme that metabolizes monoamines such as norepinephrine and serotonin, have elevated norepinephrine and serotonin levels in the frontal cortex,...

Cerebellar cortical inhibition and classical eyeblink conditioning

Bao, Shaowen, Chen, Lu, Kim, Jeansok J., Thompson, Richard F.

The cerebellum is considered a brain structure in which memories for learned motor responses (e.g., conditioned eyeblink responses) are stored. Within the cerebellum, however, the relative importance...

Solution structure and dynamics of the outer membrane enzyme PagP by NMR

Hwang, Peter M., Choy, Wing-Yiu, Lo, Eileen I., Chen, Lu, Forman-Kay, Julie D., Raetz, Christian R. H., ...

The bacterial outer membrane enzyme PagP transfers a palmitate chain from a phospholipid to lipid A. In a number of pathogenic Gram-negative bacteria, PagP confers resistance to certain cationic...

Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor number

Schnell, Eric, Sizemore, Max, Karimzadegan, Siavash, Chen, Lu, Bredt, David S., Nicoll, Roger A.

Excitatory synapses in the brain exhibit a remarkable degree of functional plasticity, which largely reflects changes in the number of synaptic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid...

Impaired Eye-Blink Conditioning in waggler, a Mutant Mouse With Cerebellar BDNF Deficiency

Bao, Shaowen, Chen, Lu, Qiao, Xiaoxi, Knusel, Beat, Thompson, Richard F.

In addition to their trophic functions, neurotrophins are also implicated in synaptic modulation and learning and memory. Although gene knockout techniques have been used widely in studying the roles...

Transgenic Brain-Derived Neurotrophic Factor Modulates a Developing Cerebellar Inhibitory Synapse

Bao, Shaowen, Chen, Lu, Qiao, Xiaoxi, Thompson, Richard F.

Brain-derived neurotrophic factor (BDNF) has been shown to promote synapse formation and maturation in neurons of many brain regions, including inhibitory synapses. In the cerebellum, the Golgi...

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

Cursiefen, Claus, Chen, Lu, Borges, Leonardo P., Jackson, David, Cao, Jingtai, Radziejewski, Czeslaw, ...

Lymphangiogenesis, an important initial step in tumor metastasis and transplant sensitization, is mediated by the action of VEGF-C and -D on VEGFR3. In contrast, VEGF-A binds VEGFR1 and VEGFR2 and is...

A hydrocarbon ruler measures palmitate in the enzymatic acylation of endotoxin

Ahn, Victoria E, Lo, Eileen I, Engel, Christian K, Chen, Lu, Hwang, Peter M, Kay, Lewis E, ...

The ability of enzymes to distinguish between fatty acyl groups can involve molecular measuring devices termed hydrocarbon rulers, but the molecular basis for acyl-chain recognition in any...

Postsynaptic assembly induced by neurexin-neuroligin interaction and neurotransmitter

Nam, Christine I., Chen, Lu

Presynaptic and postsynaptic differentiation occurs at axodendritic contacts between CNS neurons. Synaptic adhesion mediated by synaptic cell adhesion molecule (SynCAM) and β-neurexins/neuroligins...

Novel Expression and Characterization of Lymphatic Vessel Endothelial Hyaluronate Receptor 1 (LYVE-1) by Conjunctival Cells

Chen, Lu, Cursiefen, Claus, Barabino, Stefano, Zhang, Qiang, Dana, M. Reza

Purpose. Lymphatic vessel endothelial hyaluronic acid receptor (LYVE-1) is a newly discovered lymphatic-specific marker. To date, there is no report of its expression on conjunctival cells. The...

Identification of the Yeast R-SNARE Nyv1p as a Novel Longin Domain-containing Protein

Wen, Wenyu, Chen, Lu, Wu, Hao, Sun, Xin, Zhang, Mingjie, Banfield, David K.

Using nuclear magnetic resonance spectroscopy, we establish that the N-terminal domain of the yeast vacuolar R-SNARE Nyv1p adopts a longin-like fold similar to those of Sec22b and Ykt6p. Nyv1p is...

Impaired cerebellar synapse maturation in waggler, a mutant mouse with a disrupted neuronal calcium channel γ subunit

Chen, Lu, Bao, Shaowen, Qiao, Xiaoxi, Thompson, Richard F.

The waggler, a neurological mutant mouse with a disrupted putative neuronal Ca2+ channel γ subunit, exhibits a cerebellar granule cell-specific brain-derived neurotrophic factor deficit, severe...

Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice

Kim, Jeansok J., Shih, Jean C., Chen, Kevin, Chen, Lu, Bao, Shaowen, Maren, Stephen, ...

Mice deficient in monoamine oxidase A (MAOA), an enzyme that metabolizes monoamines such as norepinephrine and serotonin, have elevated norepinephrine and serotonin levels in the frontal cortex,...

Cerebellar cortical inhibition and classical eyeblink conditioning

Bao, Shaowen, Chen, Lu, Kim, Jeansok J., Thompson, Richard F.

The cerebellum is considered a brain structure in which memories for learned motor responses (e.g., conditioned eyeblink responses) are stored. Within the cerebellum, however, the relative importance...

Solution structure and dynamics of the outer membrane enzyme PagP by NMR

Hwang, Peter M., Choy, Wing-Yiu, Lo, Eileen I., Chen, Lu, Forman-Kay, Julie D., Raetz, Christian R. H., ...

The bacterial outer membrane enzyme PagP transfers a palmitate chain from a phospholipid to lipid A. In a number of pathogenic Gram-negative bacteria, PagP confers resistance to certain cationic...

Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor number

Schnell, Eric, Sizemore, Max, Karimzadegan, Siavash, Chen, Lu, Bredt, David S., Nicoll, Roger A.

Excitatory synapses in the brain exhibit a remarkable degree of functional plasticity, which largely reflects changes in the number of synaptic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid...

Impaired Eye-Blink Conditioning in waggler, a Mutant Mouse With Cerebellar BDNF Deficiency

Bao, Shaowen, Chen, Lu, Qiao, Xiaoxi, Knusel, Beat, Thompson, Richard F.

In addition to their trophic functions, neurotrophins are also implicated in synaptic modulation and learning and memory. Although gene knockout techniques have been used widely in studying the roles...

Transgenic Brain-Derived Neurotrophic Factor Modulates a Developing Cerebellar Inhibitory Synapse

Bao, Shaowen, Chen, Lu, Qiao, Xiaoxi, Thompson, Richard F.

Brain-derived neurotrophic factor (BDNF) has been shown to promote synapse formation and maturation in neurons of many brain regions, including inhibitory synapses. In the cerebellum, the Golgi...

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

Cursiefen, Claus, Chen, Lu, Borges, Leonardo P., Jackson, David, Cao, Jingtai, Radziejewski, Czeslaw, ...

Lymphangiogenesis, an important initial step in tumor metastasis and transplant sensitization, is mediated by the action of VEGF-C and -D on VEGFR3. In contrast, VEGF-A binds VEGFR1 and VEGFR2 and is...

A hydrocarbon ruler measures palmitate in the enzymatic acylation of endotoxin

Ahn, Victoria E, Lo, Eileen I, Engel, Christian K, Chen, Lu, Hwang, Peter M, Kay, Lewis E, ...

The ability of enzymes to distinguish between fatty acyl groups can involve molecular measuring devices termed hydrocarbon rulers, but the molecular basis for acyl-chain recognition in any...

Postsynaptic assembly induced by neurexin-neuroligin interaction and neurotransmitter

Nam, Christine I., Chen, Lu

Presynaptic and postsynaptic differentiation occurs at axodendritic contacts between CNS neurons. Synaptic adhesion mediated by synaptic cell adhesion molecule (SynCAM) and β-neurexins/neuroligins...

Identification of the Yeast R-SNARE Nyv1p as a Novel Longin Domain-containing Protein

Wen, Wenyu, Chen, Lu, Wu, Hao, Sun, Xin, Zhang, Mingjie, Banfield, David K.

Using nuclear magnetic resonance spectroscopy, we establish that the N-terminal domain of the yeast vacuolar R-SNARE Nyv1p adopts a longin-like fold similar to those of Sec22b and Ykt6p. Nyv1p is...

Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision

Cursiefen, Claus, Chen, Lu, Saint-Geniez, Magali, Hamrah, Pedram, Jin, Yiping, Rashid, Saadia, ...

Transparency of the cornea, the window of the eye, is a prerequisite for vision. Angiogenesis into the normally avascular cornea is incompatible with good vision and, therefore, the cornea is one of...

Spontaneous Corneal Hem- and Lymphangiogenesis in Mice with Destrin-Mutation Depend on VEGFR3 Signaling

Cursiefen, Claus, Ikeda, Sakae, Nishina, Patsy M., Smith, Richard S., Ikeda, Akihiro, Jackson, David, ...

Lymphangiogenesis, the formation of new lymphatic vessels, is important for tumor metastasis and induction of immunity to peripheral antigens including organ transplants. We herein describe a novel...

Parallel gene synthesis in a microfluidic device

Kong, David S., Carr, Peter A., Chen, Lu, Zhang, Shuguang, Jacobson, Joseph M.

The ability to synthesize custom de novo DNA constructs rapidly, accurately and inexpensively is highly desired by researchers, as synthetic genes and longer DNA constructs are enabling to numerous...

Novel Expression of Vascular Endothelial Growth Factor Receptor (VEGFR)-3 and VEGF-C on Corneal Dendritic Cells

Hamrah, Pedram, Chen, Lu, Zhang, Qiang, Dana, M. Reza

Vascular endothelial growth factor-3 (VEGFR-3) plays a critical role in embryonic cardiovascular development and is thought to be expressed exclusively on the lymphatic endothelium, high endothelial...

Cardiac implications for the use of β2-adrenoceptor agonists for the management of muscle wasting

Molenaar, Peter, Chen, Lu, Parsonage, William A

There are proposals for the implementation of β2-adrenoceptor agonists for the management of muscle wasting diseases. The idea has been initiated by studies in animal models which show that...

Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator

Stogios, Peter J., Chen, Lu, Privé, Gilbert G.

BTB-zinc finger (BTB-ZF) proteins are transcription regulators with roles in development, differentiation, and oncogenesis. In these proteins, the BTB domain (also known as the POZ domain) is a...

Crystal structures of saposins A and C

Ahn, Victoria E., Leyko, Paul, Alattia, Jean-René, Chen, Lu, Privé, Gilbert G.

Saposins A and C are sphingolipid activator proteins required for the lysosomal breakdown of galactosylceramide and glucosylceramide, respectively. The saposins interact with lipids, leading to an...

DOES INFORMATION UNDERMINE BRAND? INFORMATION INTERMEDIARY USE AND PREFERENCE FOR BRANDED WEB RETAILERS -super-*

JOEL WALDFOGEL, LU CHEN

Investments in brand, and third-party information, provide alternative methods for convincing potential customers that vendors will deliver as promised. This study uses a 13-month panel dataset on...

Protein kinase C βII and TGFβRII in ω-3 fatty acid–mediated inhibition of colon carcinogenesis

Murray, Nicole R., Weems, Capella, Chen, Lu, Leon, Jessica, Yu, Wangsheng, Davidson, Laurie A., ...

Încreasing evidence demonstrates that protein kinase C βII (PKCβII) promotes colon carcinogenesis. We previously reported that colonic PKCβII is induced during colon carcinogenesis in rodents and...

Functional studies and distribution define a family of transmembrane AMPA receptor regulatory proteins

Tomita, Susumu, Chen, Lu, Kawasaki, Yoshimi, Petralia, Ronald S., Wenthold, Robert J., Nicoll, Roger A., ...

Functional expression of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in cerebellar granule cells requires stargazin, a member of a large family of four-pass transmembrane...

Does Information Undermine Brand? Information Intermediary Use and Preference for Branded Web Retailers

Joel Waldfogel, Lu Chen

Investments in brand provide one method for vendors to become known and convince potential customers that vendors will deliver as promised. Alternatively, third-party information on retailers'...

Identification of Coevolving Residues and Coevolution Potentials Emphasizing Structure, Bond Formation and Catalytic Coordination in Protein Evolution

Little, Daniel Y., Chen, Lu

The structure and function of a protein is dependent on coordinated interactions between its residues. The selective pressures associated with a mutation at one site should therefore depend on the...

Retinoic acid regulates RARα-mediated control of translation in dendritic RNA granules during homeostatic synaptic plasticity

Maghsoodi, Bita, Poon, Michael M., Nam, Christine I., Aoto, Jason, Ting, Pamela, Chen, Lu

Homeostatic plasticity is thought to play an important role in maintaining the stability of neuronal circuits. During one form of homeostatic plasticity, referred to as synaptic scaling, activity...

Genomic Biomarkers to Improve Ulcerative Colitis Neoplasia Surveillance

Bronner, Mary P., O'Sullivan, Jacintha N., Rabinovitch, Peter S., Crispin, David A., Chen, Lu, Emond, Mary J., ...

No adequate means exist to identify the minority of ulcerative colitis (UC) patients destined to undergo neoplastic progression. Recognition of this subset would advance UC cancer surveillance by...

Retinoic acid-gated sequence-specific translational control by RARα

Poon, Michael M., Chen, Lu

Retinoic acid (RA) plays important roles in development by modulating gene transcription through nuclear receptor activation. Increasing evidence supports a role for RA and RA receptors (RARs) in...

Processing of G4 DNA by Dna2 Helicase/Nuclease and Replication Protein A (RPA) Provides Insights into the Mechanism of Dna2/RPA Substrate Recognition*

Masuda-Sasa, Taro, Polaczek, Piotr, Peng, Xiao P., Chen, Lu, Campbell, Judith L.

The polyguanine-rich DNA sequences commonly found at telomeres and in rDNA arrays have been shown to assemble into structures known as G quadruplexes, or G4 DNA, stabilized by base-stacked G...