An experimentally derived confidence score for binary protein-protein interactions (2009)
Braun, Pascal, Tasan, Murat, Dreze, Matija, Barrios-Rodiles, Miriam, Lemmens, Irma, Yu, Haiyuan, ...
Information on protein-protein interactions is of central importance for many areas of biomedical research. At present no method exists to systematically and experimentally assess the quality of...
Human Gliomas, Hao Ding, Luba Roncari, Patrick Shannon, Xiaoli Wu, Nelson Lau, ...
Activation of the p21-ras signaling pathway from aberrantly expressed receptors promotes the growth of malignant human astrocytomas. We developed a transgenic mouse astrocytoma model using the glial...
Expression and hypoxic regulation of angiopoietins in human astrocytomas (2001)
Ding, Hao, Roncari, Luba, Wu, Xiaoli, Lau, Nelson, Shannon, Patrick, Nagy, Andras, ...
Vascular endothelial growth factor (VEGF) is a major inducer of tumor angiogenesis and edema in human astrocytomas by its interaction with cognate endothelial-specific receptors (VEGFR1/R2). Tie1 and...
Hao Ding, Patrick Shannon, Nelson Lau, Xiaoli Wu, Luba Roncari, Rebecca L. Baldwin, ...
A significant proportion of human malignant gliomas exhibit amplification, overexpression, or mutations of the epidermal growth factor receptor (EGFR). To define the functional role(s) of the EGFR in...
Okada, Futoshi, Rak, Janusz W., Croix, Brad St., Lieubeau, Blandine, Kaya, Mitsunori, Roncari, Luba, ...
Targeted disruption of the single mutant K-ras allele in two human colorectal carcinoma cell lines (DLD-1 and HCT-116) leads to loss of tumorigenic competence in nude mice with retention of ability...
Okada, Futoshi, Rak, Janusz W., Croix, Brad St., Lieubeau, Blandine, Kaya, Mitsunori, Roncari, Luba, ...
Targeted disruption of the single mutant K-ras allele in two human colorectal carcinoma cell lines (DLD-1 and HCT-116) leads to loss of tumorigenic competence in nude mice with retention of ability...