Lubomir Prochazka

Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II (2007)

Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...

Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...

Apoptosis and inhibition of gap-junctional intercellular communication induced by LA-12, a novel hydrophobic platinum(IV) complex (2007)

Prochazka, Lubomir, Turanek, Jaroslav, Tesarik, Radek, Knotigova, Pavlina, Polaskova, Pavlina, Andrysik, Zdenek, ...

A new hydrophobic platinum(IV) complex, LA-12, a very efficient anticancer drug lacking cross-resistance with cisplatin (CDDP), is now being tested in clinical trials. Here we investigated the...

Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)

Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...

Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...

Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria (2007)

Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...

Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...

Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: the role of oxidative stress (2007)

Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...

''Mitocans'' from the vitamin E group of selective anticancer drugs, A-tocopheryl succinate (A-TOS) and its ether analogue A-TEA, triggered apoptosis in proliferating but not arrested endothelial...

Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II (2007)

Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...

Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...

Apoptosis and inhibition of gap-junctional intercellular communication induced by LA-12, a novel hydrophobic platinum(IV) complex (2007)

Prochazka, Lubomir, Turanek, Jaroslav, Tesarik, Radek, Knotigova, Pavlina, Polaskova, Pavlina, Andrysik, Zdenek, ...

A new hydrophobic platinum(IV) complex, LA-12, a very efficient anticancer drug lacking cross-resistance with cisplatin (CDDP), is now being tested in clinical trials. Here we investigated the...

Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)

Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...

Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...

Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria (2007)

Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...

Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial celss: the role of oxidative stress (2007)

Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...

Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)

Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...

Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...

Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria (2007)

Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...

Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...

Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: the role of oxidative stress (2007)

Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...

''Mitocans'' from the vitamin E group of selective anticancer drugs, A-tocopheryl succinate (A-TOS) and its ether analogue A-TEA, triggered apoptosis in proliferating but not arrested endothelial...

Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II (2007)

Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...

Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...

Apoptosis and inhibition of gap-junctional intercellular communication induced by LA-12, a novel hydrophobic platinum(IV) complex (2007)

Prochazka, Lubomir, Turanek, Jaroslav, Tesarik, Radek, Knotigova, Pavlina, Polaskova, Pavlina, Andrysik, Zdenek, ...

A new hydrophobic platinum(IV) complex, LA-12, a very efficient anticancer drug lacking cross-resistance with cisplatin (CDDP), is now being tested in clinical trials. Here we investigated the...

Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)

Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...

Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...

Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria (2007)

Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...

Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...

Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: the role of oxidative stress (2007)

Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...

''Mitocans'' from the vitamin E group of selective anticancer drugs, A-tocopheryl succinate (A-TOS) and its ether analogue A-TEA, triggered apoptosis in proliferating but not arrested endothelial...