Genome bioinformatic analysis of nonsynonymous SNPs (2007)
Burke, David F, Worth, Catherine L, Priego, Eva-Maria, Cheng, Tammy, Smink, Luc J, Todd, John A, ...
Abstract Background Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the most common of...
Nejentsev, Sergey, Smink, Luc J, Smyth, Deborah, Bailey, Rebecca, Lowe, Christopher E, Payne, Felicity, ...
Abstract Background In an effort to locate susceptibility genes for type 1 diabetes (T1D) several genome-wide linkage scans have been undertaken. A chromosomal region designated IDDM10 retained...
T1DBase: integration and presentation of complex data for type 1 diabetes research (2007)
Hulbert, Erin M., Smink, Luc J., Adlem, Ellen C., Allen, James E., Burdick, David B., Burren, Oliver S., ...
T1DBase (http://T1DBase.org) [Smink et al. (2005) Nucleic Acids Res., 33, D544–D549; Burren et al. (2004) Hum. Genomics, 1, 98–109] is a public website and database that supports the type 1...
Taniguchi, Hidenori, Lowe, Christopher E, Cooper, Jason D, Smyth, Deborah J, Bailey, Rebecca, Nutland, Sarah, ...
Abstract Background Type 1 diabetes (T1D) is a common autoimmune disease resulting from T-cell mediated destruction of pancreatic beta cells. Decay accelerating factor (DAF, CD55), a...
T1DBase: integration and presentation of complex data for type 1 diabetes research (2006)
Hulbert, Erin M., Smink, Luc J., Adlem, Ellen C., E. Allen, James, Burdick, David B., Burren, Oliver S., ...
T1DBase (http://T1DBase.org) [Smink et al. (2005) Nucleic Acids Res., 33, D544–D549; Burren et al. (2004) Hum. Genomics, 1, 98–109] is a public website and database that supports the type 1...
T1DBase: integration and presentation of complex data for type 1 diabetes research (2006)
Hulbert, Erin M., Smink, Luc J., Adlem, Ellen C., E. Allen, James, Burdick, David B., Burren, Oliver S., ...
T1DBase (http://T1DBase.org) [Smink et al. (2005) Nucleic Acids Res., 33, D544–D549; Burren et al. (2004) Hum. Genomics, 1, 98–109] is a public website and database that supports the type 1...
Maier, Lisa M, Smyth, Deborah J, Vella, Adrian, Payne, Felicity, Cooper, Jason D, Pask, Rebecca, ...
Abstract Background One strategy to help identify susceptibility genes for complex, multifactorial diseases is to map disease loci in a representative animal model of the disorder. The nonobese...
T1DBase, a community web-based resource for type 1 diabetes research (2005)
Luc J. Smink, Erin M. Helton, Barry C. Healy, Christopher C. Cavnor, Alex C. Lam, Daisy Flamez, ...
doi:10.1093/nar/gki095
T1DBase, a community web-based resource for type 1 diabetes research (2005)
Smink, Luc J., Helton, Erin M., Healy, Barry C., Cavnor, Christopher C., Lam, Alex C., Flamez, Daisy, ...
T1DBase (http://T1DBase.org) is a public website and database that supports the type 1 diabetes (T1D) research community. The site is currently focused on the molecular genetics and biology of T1D...
Pask, Rebecca, Rance, Helen E, Barratt, Bryan J, Nutland, Sarah, Smyth, Deborah J, Sebastian, Meera, ...
Abstract Background Sustainable DNA resources and reliable high-throughput genotyping methods are required for large-scale, long-term genetic association studies. In the genetic dissection of common...
Reevaluating Human Gene Annotation: A Second-Generation Analysis of Chromosome 22 (2003)
Collins, John E., Goward, Melanie E., Cole, Charlotte G., Smink, Luc J., Huckle, Elizabeth J., Knowles, Sarah, ...
We report a second-generation gene annotation of human chromosome 22. Using expressed sequence databases, comparative sequence analysis, and experimental verification, we have extended genes, fused...
Reevaluating Human Gene Annotation: A Second-Generation Analysis of Chromosome 22 (2002)
Collins, John E., Goward, Melanie E., Cole, Charlotte G., Smink, Luc J., Huckle, Elizabeth J., Knowles, Sarah, ...
A bacterial artificial chromosome-based framework contig map of human chromosome 22q (1996)
Kim, Ung-Jin, Shizuya, Hiroaki, Kang, Hyung-Lyun, Choi, Sun-Shim, Garrett, Charmain L., Smink, Luc J., ...
We have constructed a physical map of human chromosome 22q using bacterial artificial chromosome (BAC) clones. The map consists of 613 chromosome 22-specific BAC clones that have been localized and...
A SNP Resource for Human Chromosome 22: Extracting Dense Clusters of SNPs From the Genomic Sequence
Dawson, Elisabeth, Chen, Yuan, Hunt, Sarah, Smink, Luc J., Hunt, Adrienne, Rice, Kate, ...
The recent publication of the complete sequence of human chromosome 22 provides a platform from which to investigate genomic sequence variation. We report the identification and characterization of...
Reevaluating Human Gene Annotation: A Second-Generation Analysis of Chromosome 22
Collins, John E., Goward, Melanie E., Cole, Charlotte G., Smink, Luc J., Huckle, Elizabeth J., Knowles, Sarah, ...
We report a second-generation gene annotation of human chromosome 22. Using expressed sequence databases, comparative sequence analysis, and experimental verification, we have extended genes, fused...
Pask, Rebecca, Rance, Helen E, Barratt, Bryan J, Nutland, Sarah, Smyth, Deborah J, Sebastian, Meera, ...
T1DBase, a community web-based resource for type 1 diabetes research
Smink, Luc J., Helton, Erin M., Healy, Barry C., Cavnor, Christopher C., Lam, Alex C., Flamez, Daisy, ...
T1DBase (http://T1DBase.org) is a public website and database that supports the type 1 diabetes (T1D) research community. The site is currently focused on the molecular genetics and biology of T1D...
Maier, Lisa M, Smyth, Deborah J, Vella, Adrian, Payne, Felicity, Cooper, Jason D, Pask, Rebecca, ...
Taniguchi, Hidenori, Lowe, Christopher E, Cooper, Jason D, Smyth, Deborah J, Bailey, Rebecca, Nutland, Sarah, ...
A SNP Resource for Human Chromosome 22: Extracting Dense Clusters of SNPs From the Genomic Sequence
Dawson, Elisabeth, Chen, Yuan, Hunt, Sarah, Smink, Luc J., Hunt, Adrienne, Rice, Kate, ...
The recent publication of the complete sequence of human chromosome 22 provides a platform from which to investigate genomic sequence variation. We report the identification and characterization of...
Reevaluating Human Gene Annotation: A Second-Generation Analysis of Chromosome 22
Collins, John E., Goward, Melanie E., Cole, Charlotte G., Smink, Luc J., Huckle, Elizabeth J., Knowles, Sarah, ...
We report a second-generation gene annotation of human chromosome 22. Using expressed sequence databases, comparative sequence analysis, and experimental verification, we have extended genes, fused...
Pask, Rebecca, Rance, Helen E, Barratt, Bryan J, Nutland, Sarah, Smyth, Deborah J, Sebastian, Meera, ...
T1DBase, a community web-based resource for type 1 diabetes research
Smink, Luc J., Helton, Erin M., Healy, Barry C., Cavnor, Christopher C., Lam, Alex C., Flamez, Daisy, ...
T1DBase (http://T1DBase.org) is a public website and database that supports the type 1 diabetes (T1D) research community. The site is currently focused on the molecular genetics and biology of T1D...
Maier, Lisa M, Smyth, Deborah J, Vella, Adrian, Payne, Felicity, Cooper, Jason D, Pask, Rebecca, ...
Taniguchi, Hidenori, Lowe, Christopher E, Cooper, Jason D, Smyth, Deborah J, Bailey, Rebecca, Nutland, Sarah, ...
T1DBase: integration and presentation of complex data for type 1 diabetes research
Hulbert, Erin M., Smink, Luc J., Adlem, Ellen C., Allen, James E., Burdick, David B., Burren, Oliver S., ...
T1DBase () [Smink et al. (2005) Nucleic Acids Res., 33, D544–D549; Burren et al. (2004) Hum. Genomics, 1, 98–109] is a public website and database that supports the type 1 diabetes (T1D) research...