Luciana C. C. Leite

Recombinant Mycobacterium bovis BCG Expressing the Sm14 Antigen of Schistosoma mansoni Protects Mice from Cercarial Challenge (2004)

Varaldo, Paula B., Leite, Luciana C. C., Dias, Waldely O., Miyaji, Eliane N., Torres, Fabio I. G., Gebara, Vera C., ...

The Sm14 antigen of Schistosoma mansoni was cloned and expressed in Mycobacterium bovis BCG as a fusion with the Mycobacterium fortuitum β-lactamase protein under the control of its promoter,...

Identification of human chromosome 22 transcribed sequences with ORF expressed sequence tags

De Souza, Sandro J., Camargo, Anamaria A., Briones, Marcelo R. S., Costa, Fernando F., Nagai, Maria Aparecida, Verjovski-Almeida, Sergio, ...

Transcribed sequences in the human genome can be identified with confidence only by alignment with sequences derived from cDNAs synthesized from naturally occurring mRNAs. We constructed a set of...

The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome

Camargo, Anamaria A., Samaia, Helena P. B., Dias-Neto, Emmanuel, Simão, Daniel F., Migotto, Italo A., Briones, Marcelo R. S., ...

Open reading frame expressed sequences tags (ORESTES) differ from conventional ESTs by providing sequence data from the central protein coding portion of transcripts. We generated a total of 696,745...

Induction of Neutralizing Antibodies against Diphtheria Toxin by Priming with Recombinant Mycobacterium bovis BCG Expressing CRM197, a Mutant Diphtheria Toxin

Miyaji, Eliane N., Mazzantini, Rogerio P., Dias, Waldely O., Marcovistz, Rugimar, Matos, Denise S., ...

BCG, the attenuated strain of Mycobacterium bovis, has been widely used as a vaccine against tuberculosis and is thus an important candidate as a live carrier for multiple antigens. With the aim of...

Recombinant Mycobacterium bovis BCG Expressing Pertussis Toxin Subunit S1 Induces Protection against an Intracerebral Challenge with Live Bordetella pertussis in Mice

Nascimento, Ivan P., Dias, Waldely O., Mazzantini, Rogerio P., Miyaji, Eliane N., Gamberini, Marcia, Quintilio, Wagner, ...

Recombinant Mycobacterium bovis BCG Expressing Pertussis Toxin Subunit S1 Induces Protection against an Intracerebral Challenge with Live Bordetella pertussis in Mice

Nascimento, Ivan P., Dias, Waldely O., Mazzantini, Rogerio P., Miyaji, Eliane N., Gamberini, Marcia, Quintilio, Wagner, ...

The recent development of acellular pertussis vaccines has been a significant improvement in the conventional whole-cell diphtheria-pertussis-tetanus toxoid vaccines, but high production costs will...

Analysis of Serum Cross-Reactivity and Cross-Protection Elicited by Immunization with DNA Vaccines against Streptococcus pneumoniae Expressing PspA Fragments from Different Clades

Miyaji, Eliane N., Ferreira, Daniela M., Lopes, Alexandre P. Y., Brandileone, M. Cristina C., Dias, Waldely O., Leite, Luciana C. C.

Streptococcus pneumoniae is a major cause of disease, especially in developing countries, and cost-effective alternatives to the currently licensed vaccines are needed. We constructed DNA vaccines...

Saci-1, -2, and -3 and Perere, Four Novel Retrotransposons with High Transcriptional Activities from the Human Parasite Schistosoma mansoni

DeMarco, Ricardo, Kowaltowski, Andre T., Machado, Abimael A., Soares, M. Bento, Gargioni, Cybele, Kawano, Toshie, ...

Using the data set of 180,000 expressed sequence tags (ESTs) of the blood fluke Schistosoma mansoni generated recently by our group, we identified three novel long-terminal-repeat (LTR)- and one...

Saci-1, -2, and -3 and Perere, Four Novel Retrotransposons with High Transcriptional Activities from the Human Parasite Schistosoma mansoni

DeMarco, Ricardo, Kowaltowski, Andre T., Machado, Abimael A., Soares, M. Bento, Gargioni, Cybele, Kawano, Toshie, ...

Recombinant Mycobacterium bovis BCG Expressing the Sm14 Antigen of Schistosoma mansoni Protects Mice from Cercarial Challenge

Varaldo, Paula B., Leite, Luciana C. C., Dias, Waldely O., Miyaji, Eliane N., Torres, Fabio I. G., Gebara, Vera C., ...

The Sm14 antigen of Schistosoma mansoni was cloned and expressed in Mycobacterium bovis BCG as a fusion with the Mycobacterium fortuitum β-lactamase protein under the control of its promoter,...

Multiserotype Protection of Mice against Pneumococcal Colonization of the Nasopharynx and Middle Ear by Killed Nonencapsulated Cells Given Intranasally with a Nontoxic Adjuvant

Malley, Richard, Morse, Sarah C., Leite, Luciana C. C., Areas, Ana Paula Mattos, Ho, Paulo Lee, Kubrusly, Flavia S., ...

Intranasal challenge of C57BL/6 mice with Streptococcus pneumoniae serotypes 6B, 14, and 23F produced colonization of the middle ear and NP. Intranasal vaccination with ethanol-killed nonencapsulated...

Genetic Diversity of PspA Types among Nasopharyngeal Isolates Collected during an Ongoing Surveillance Study of Children in Brazil

Pimenta, Fabiana Cristina, Ribeiro-Dias, Fátima, Brandileone, Maria Cristina C., Miyaji, Eliane N., Leite, Luciana C. C.

Pneumococcal surface protein A (PspA) has been considered a potential candidate for human vaccines because of its serotype-independent protective immunity. Nasopharyngeal (NP) pneumococcal...

Identification of human chromosome 22 transcribed sequences with ORF expressed sequence tags

De Souza, Sandro J., Camargo, Anamaria A., Briones, Marcelo R. S., Costa, Fernando F., Nagai, Maria Aparecida, Verjovski-Almeida, Sergio, ...

Transcribed sequences in the human genome can be identified with confidence only by alignment with sequences derived from cDNAs synthesized from naturally occurring mRNAs. We constructed a set of...

The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome

Camargo, Anamaria A., Samaia, Helena P. B., Dias-Neto, Emmanuel, Simão, Daniel F., Migotto, Italo A., Briones, Marcelo R. S., ...

Open reading frame expressed sequences tags (ORESTES) differ from conventional ESTs by providing sequence data from the central protein coding portion of transcripts. We generated a total of 696,745...

Induction of Neutralizing Antibodies against Diphtheria Toxin by Priming with Recombinant Mycobacterium bovis BCG Expressing CRM197, a Mutant Diphtheria Toxin

Miyaji, Eliane N., Mazzantini, Rogerio P., Dias, Waldely O., Marcovistz, Rugimar, Matos, Denise S., ...

BCG, the attenuated strain of Mycobacterium bovis, has been widely used as a vaccine against tuberculosis and is thus an important candidate as a live carrier for multiple antigens. With the aim of...

Recombinant Mycobacterium bovis BCG Expressing Pertussis Toxin Subunit S1 Induces Protection against an Intracerebral Challenge with Live Bordetella pertussis in Mice

Nascimento, Ivan P., Dias, Waldely O., Mazzantini, Rogerio P., Miyaji, Eliane N., Gamberini, Marcia, Quintilio, Wagner, ...

Recombinant Mycobacterium bovis BCG Expressing Pertussis Toxin Subunit S1 Induces Protection against an Intracerebral Challenge with Live Bordetella pertussis in Mice

Nascimento, Ivan P., Dias, Waldely O., Mazzantini, Rogerio P., Miyaji, Eliane N., Gamberini, Marcia, Quintilio, Wagner, ...

The recent development of acellular pertussis vaccines has been a significant improvement in the conventional whole-cell diphtheria-pertussis-tetanus toxoid vaccines, but high production costs will...

Analysis of Serum Cross-Reactivity and Cross-Protection Elicited by Immunization with DNA Vaccines against Streptococcus pneumoniae Expressing PspA Fragments from Different Clades

Miyaji, Eliane N., Ferreira, Daniela M., Lopes, Alexandre P. Y., Brandileone, M. Cristina C., Dias, Waldely O., Leite, Luciana C. C.

Streptococcus pneumoniae is a major cause of disease, especially in developing countries, and cost-effective alternatives to the currently licensed vaccines are needed. We constructed DNA vaccines...

Saci-1, -2, and -3 and Perere, Four Novel Retrotransposons with High Transcriptional Activities from the Human Parasite Schistosoma mansoni

DeMarco, Ricardo, Kowaltowski, Andre T., Machado, Abimael A., Soares, M. Bento, Gargioni, Cybele, Kawano, Toshie, ...

Using the data set of 180,000 expressed sequence tags (ESTs) of the blood fluke Schistosoma mansoni generated recently by our group, we identified three novel long-terminal-repeat (LTR)- and one...

Saci-1, -2, and -3 and Perere, Four Novel Retrotransposons with High Transcriptional Activities from the Human Parasite Schistosoma mansoni

DeMarco, Ricardo, Kowaltowski, Andre T., Machado, Abimael A., Soares, M. Bento, Gargioni, Cybele, Kawano, Toshie, ...

Recombinant Mycobacterium bovis BCG Expressing the Sm14 Antigen of Schistosoma mansoni Protects Mice from Cercarial Challenge

Varaldo, Paula B., Leite, Luciana C. C., Dias, Waldely O., Miyaji, Eliane N., Torres, Fabio I. G., Gebara, Vera C., ...

The Sm14 antigen of Schistosoma mansoni was cloned and expressed in Mycobacterium bovis BCG as a fusion with the Mycobacterium fortuitum β-lactamase protein under the control of its promoter,...

Multiserotype Protection of Mice against Pneumococcal Colonization of the Nasopharynx and Middle Ear by Killed Nonencapsulated Cells Given Intranasally with a Nontoxic Adjuvant

Malley, Richard, Morse, Sarah C., Leite, Luciana C. C., Areas, Ana Paula Mattos, Ho, Paulo Lee, Kubrusly, Flavia S., ...

Intranasal challenge of C57BL/6 mice with Streptococcus pneumoniae serotypes 6B, 14, and 23F produced colonization of the middle ear and NP. Intranasal vaccination with ethanol-killed nonencapsulated...

Genetic Diversity of PspA Types among Nasopharyngeal Isolates Collected during an Ongoing Surveillance Study of Children in Brazil

Pimenta, Fabiana Cristina, Ribeiro-Dias, Fátima, Brandileone, Maria Cristina C., Miyaji, Eliane N., Leite, Luciana C. C.

Pneumococcal surface protein A (PspA) has been considered a potential candidate for human vaccines because of its serotype-independent protective immunity. Nasopharyngeal (NP) pneumococcal...

Optimized Immune Response Elicited by a DNA Vaccine Expressing Pneumococcal Surface Protein A Is Characterized by a Balanced Immunoglobulin G1 (IgG1)/IgG2a Ratio and Proinflammatory Cytokine Production▿

Ferreira, Daniela M., Darrieux, Michelle, Oliveira, Maria Leonor S., Leite, Luciana C. C., Miyaji, Eliane N.

We have previously shown that DNA immunization with PspA (pneumococcal surface protein A) DNA is able to elicit protection comparable to that elicited by immunization with PspA protein (with alum as...