Perfettini, Jean-Luc, Nardacci, Roberta, Bourouba, Mehdi, Subra, Frédéric, Gros, Laurent, Séror, Claire, ...
DNA damage can activate the oncosuppressor protein ataxia telangiectasia mutated (ATM), which phosphorylates the histone H2AX within characteristic DNA damage foci. Here, we show that ATM undergoes...
Perfettini, Jean-Luc, Nardacci, Roberta, Bourouba, Mehdi, Subra, Frédéric, Gros, Laurent, Séror, Claire, ...
DNA damage can activate the oncosuppressor protein ataxia telangiectasia mutated (ATM), which phosphorylates the histone H2AX within characteristic DNA damage foci. Here, we show that ATM undergoes...
Perfettini, Jean-Luc, Nardacci, Roberta, Bourouba, Mehdi, Subra, Frédéric, Gros, Laurent, Séror, Claire, ...
DNA damage can activate the oncosuppressor protein ataxia telangiectasia mutated (ATM), which phosphorylates the histone H2AX within characteristic DNA damage foci. Here, we show that ATM undergoes...
SMC1 involvement in fragile site expression (2005)
Musio, Antonio, Montagna, Cristina, Mariani, Tullio, Tilenni, Manuela, Focarelli, Maria Luisa, Brait, Lorenzo, ...
Common fragile sites have been involved in neoplastic transformation, although their molecular basis is still poorly understood. Here, we demonstrate that inhibition of the SMC1 by RNAi is sufficient...
SMC1 INVOLVEMENT IN FRAGILE SITE EXPRESSION (2005)
Musio, Antonio, Montagna, Cristina, Mariani, Tullio, Tilenni, Manuela, Focarelli, Maria Luisa, Brait, Lorenzo, ...
Common fragile sites have been involved in neoplastic transformation, although their molecular basis is still poorly understood. Here, we demonstrate that inhibition of the SMC1 by RNAi is sufficient...
Delia, Domenico, Piane, Maria, Buscemi, Giacomo, Savio, Camilla, Palmeri, Silvia, Lulli, Patrizia, ...
Hypomorphic mutations of the MRE11 gene are the hallmark of the radiosensitive ataxia-telangiectasia-like disorder (ATLD). Here we describe a new family with two affected siblings, ATLD5 and ATLD6,...
Delia, Domenico, Piane, Maria, Buscemi, Giacomo, Savio, Camilla, Palmeri, Silvia, Lulli, Patrizia, ...
Hypomorphic mutations of the MRE11 gene are the hallmark of the radiosensitive ataxia-telangiectasia-like disorder (ATLD). Here, we describe a new family with two affected siblings, ATLD5 and ATLD6,...
Delia, Domenico, Piane, Maria, Buscemi, Giacomo, Savio, Camilla, Palmeri, Silvia, Lulli, Patrizia, ...
Hypomorphic mutations of the MRE11 gene are the hallmark of the radiosensitive ataxia-telangiectasia-like disorder (ATLD). Here we describe a new family with two affected siblings, ATLD5 and ATLD6,...
Rika Tsuchida, Takayuki Yamada, Masatoshi Takagi, Akira Shimada, Chikashi Ishioka, Yoko Katsuki, ...
Tsuchida, R., Yamada, T., Takagi, M., Shimada, A., Ishioka, Katsuki, Y., C., Igarashi, T., Chessa, L., Delia, D., Teraoka, H. and Mizutani, S. Detection of ATM Gene Mutation in Human Glioma Cell Line...
Pitts, Sharon A., Kullar, Harjit S., Stankovic, Tatjana, Stewart, Grant S., Last, James I. K., Bedenham, Tina, ...
We showed recently that mutation of the hMRE11 gene identified a new ataxia telangiectasia-like disorder (ATLD). In this report we describe the genomic organization of the hMRE11 gene and the...
Brown, Kevin D., Ziv, Yael, Sadanandan, Sunanda N., Chessa, Luciana, Collins, Francis S., Shiloh, Yosef, ...
The product of the ataxia-telangiectasia gene (ATM) was identified by using an antiserum developed to a peptide corresponding to the deduced amino acid sequence. The ATM protein is a single,...
Chk2 Activation Dependence on Nbs1 after DNA Damage
Buscemi, Giacomo, Savio, Camilla, Zannini, Laura, Miccichè, Francesca, Masnada, Debora, Nakanishi, Makoto, ...
The checkpoint kinase Chk2 has a key role in delaying cell cycle progression in response to DNA damage. Upon activation by low-dose ionizing radiation (IR), which occurs in an ataxia telangiectasia...
Brown, Kevin D., Ziv, Yael, Sadanandan, Sunanda N., Chessa, Luciana, Collins, Francis S., Shiloh, Yosef, ...
The product of the ataxia-telangiectasia gene (ATM) was identified by using an antiserum developed to a peptide corresponding to the deduced amino acid sequence. The ATM protein is a single,...
Chk2 Activation Dependence on Nbs1 after DNA Damage
Buscemi, Giacomo, Savio, Camilla, Zannini, Laura, Miccichè, Francesca, Masnada, Debora, Nakanishi, Makoto, ...
The checkpoint kinase Chk2 has a key role in delaying cell cycle progression in response to DNA damage. Upon activation by low-dose ionizing radiation (IR), which occurs in an ataxia telangiectasia...
ATM and the DNA damage response
Lavin, Martin F, Delia, Domenico, Chessa, Luciana
Workshop on Ataxia-Telangiectasia and Related Syndromes
Lange, Ethan, Borresen, Anna-Lise, Chen, Xiaoguang, Chessa, Luciana, Chiplunkar, Sujata, Concannon, Patrick, ...
We describe a 20-point linkage analysis map of chromosome 11q22-23 that is based on genotyping 249 families (59 CEPH and 190 A-T). Monte Carlo linkage analyses of 176 ataxia-telangiectasia (A-T)...
Suraweera, Amila, Becherel, Olivier J., Chen, Philip, Rundle, Natalie, Woods, Rick, Nakamura, Jun, ...
Adefective response to DNA damage is observed in several human autosomal recessive ataxias with oculomotor apraxia, including ataxia-telangiectasia. We report that senataxin, defective in ataxia...
Perfettini, Jean-Luc, Nardacci, Roberta, Bourouba, Mehdi, Subra, Frédéric, Gros, Laurent, Séror, Claire, ...
DNA damage can activate the oncosuppressor protein ataxia telangiectasia mutated (ATM), which phosphorylates the histone H2AX within characteristic DNA damage foci. Here, we show that ATM undergoes...