Lucy Dorrell

Detection of broad functional gag-specific CD4+ T cell responses in HIV-1-infected subjects following therapeutic immunization with rMVA expressing an HIV-1 gag immunogen (2006)

Ondondo, Beatrice, Yang, Hongbing, Dong, Tao, Gleria, Kati De, Suttill, Annie, Conlon, Christopher, ...

No abstract available.

Antigen-presenting cell function in HIV infection and tuberculosis. (1997)

Dorrell, Lucy.

Thesis (MD)--University of Southampton, 1997.

Distinct Recognition of Non-Clade B Human Immunodeficiency Virus Type 1 Epitopes by Cytotoxic T Lymphocytes Generated from Donors Infected in Africa

Dorrell, Lucy, Dong, Tao, Ogg, Graham S., Lister, Simon, McAdam, Steve, Rostron, Tim, ...

We present detailed studies of human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte (CTL) responses to clade A or C HIV type 1 in three donors infected in East Africa. We define several...

Induction of Multifunctional Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T Cells Capable of Proliferation in Healthy Subjects by Using a Prime-Boost Regimen of DNA- and Modified Vaccinia Virus Ankara-Vectored Vaccines Expressing HIV-1 Gag Coupled to CD8+ T-Cell Epitopes†

Goonetilleke, Nilu, Moore, Stephen, Dally, Len, Winstone, Nicola, Cebere, Inese, Mahmoud, Abdul, ...

A double-blind randomized phase I trial was conducted in human immunodeficiency virus type 1 (HIV-1)-negative subjects receiving vaccines vectored by plasmid DNA and modified vaccinia virus Ankara...

Expansion and Diversification of Virus-Specific T Cells following Immunization of Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals with a Recombinant Modified Vaccinia Virus Ankara/HIV-1 Gag Vaccine

Dorrell, Lucy, Yang, Hongbing, Ondondo, Beatrice, Dong, Tao, Di Gleria, Kati, Suttill, Annie, ...

Affordable therapeutic strategies that induce sustained control of human immunodeficiency virus type 1 (HIV-1) replication and are tailored to the developing world are urgently needed. Since CD8+ and...

Distinct Recognition of Non-Clade B Human Immunodeficiency Virus Type 1 Epitopes by Cytotoxic T Lymphocytes Generated from Donors Infected in Africa

Dorrell, Lucy, Dong, Tao, Ogg, Graham S., Lister, Simon, McAdam, Steve, Rostron, Tim, ...

We present detailed studies of human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte (CTL) responses to clade A or C HIV type 1 in three donors infected in East Africa. We define several...

Induction of Multifunctional Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T Cells Capable of Proliferation in Healthy Subjects by Using a Prime-Boost Regimen of DNA- and Modified Vaccinia Virus Ankara-Vectored Vaccines Expressing HIV-1 Gag Coupled to CD8+ T-Cell Epitopes†

Goonetilleke, Nilu, Moore, Stephen, Dally, Len, Winstone, Nicola, Cebere, Inese, Mahmoud, Abdul, ...

A double-blind randomized phase I trial was conducted in human immunodeficiency virus type 1 (HIV-1)-negative subjects receiving vaccines vectored by plasmid DNA and modified vaccinia virus Ankara...

Expansion and Diversification of Virus-Specific T Cells following Immunization of Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals with a Recombinant Modified Vaccinia Virus Ankara/HIV-1 Gag Vaccine

Dorrell, Lucy, Yang, Hongbing, Ondondo, Beatrice, Dong, Tao, Di Gleria, Kati, Suttill, Annie, ...

Affordable therapeutic strategies that induce sustained control of human immunodeficiency virus type 1 (HIV-1) replication and are tailored to the developing world are urgently needed. Since CD8+ and...

Detection of broad functional gag-specific CD4+ T cell responses in HIV-1-infected subjects following therapeutic immunization with rMVA expressing an HIV-1 gag immunogen

Ondondo, Beatrice, Yang, Hongbing, Dong, Tao, Gleria, Kati De, Suttill, Annie, Conlon, Christopher, ...

Design and Pre-Clinical Evaluation of a Universal HIV-1 Vaccine

Létourneau, Sven, Im, Eung-Jun, Mashishi, Tumelo, Brereton, Choechoe, Bridgeman, Anne, Yang, Hongbing, ...

T Cell Cross-Reactivity and Conformational Changes during TCR Engagement

Lee, Jean K., Stewart-Jones, Guillaume, Dong, Tao, Harlos, Karl, Di Gleria, Kati, Dorrell, Lucy, ...

All thymically selected T cells are inherently cross-reactive, yet many data indicate a fine specificity in antigen recognition, which enables virus escape from immune control by mutation in...