Krebs, Luke T., Shutter, John R., Tanigaki, Kenji, Honjo, Tasuku, Stark, Kevin L., Gridley, Thomas
The Notch signaling pathway is essential for embryonic vascular development in vertebrates. Here we show that mouse embryos heterozygous for a targeted mutation in the gene encoding the DLL4 ligand...
Krebs, Luke T., Shutter, John R., Tanigaki, Kenji, Honjo, Tasuku, Stark, Kevin L., Gridley, Thomas
The Notch signaling pathway is essential for embryonic vascular development in vertebrates. Here we show that mouse embryos heterozygous for a targeted mutation in the gene encoding the DLL4 ligand...
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells (2004)
Domenga, Valérie, Fardoux, Peggy, Lacombe, Pierre, Monet, Marie, Maciazek, Jacqueline, Krebs, Luke T., ...
Formation of a fully functional artery proceeds through a multistep process. Here we show that Notch3 is required to generate functional arteries in mice by regulating arterial differentiation and...
Krebs, Luke T., Shutter, John R., Tanigaki, Kenji, Honjo, Tasuku, Stark, Kevin L., Gridley, Thomas
The Notch signaling pathway is essential for embryonic vascular development in vertebrates. Here we show that mouse embryos heterozygous for a targeted mutation in the gene encoding the DLL4 ligand...
Notch signaling regulates left-right asymmetry determination by inducing Nodal expression (2003)
Krebs, Luke T., Iwai, Naomi, Nonaka, Shigenori, Welsh, Ian C., Lan, Yu, Jiang, Rulang, ...
Notch signaling regulates left-right asymmetry determination by inducing Nodal expression (2003)
Krebs, Luke T., Iwai, Naomi, Nonaka, Shigenori, Welsh, Ian C., Lan, Yu, Jiang, Rulang, ...
Notch signaling is essential for vascular morphogenesis in mice (2000)
Krebs, Luke T., Xue, Yingzi, Norton, Christine R., Shutter, John R., Maguire, Maureen, Sundberg, John P., ...
Thesis (M.S. Ed.)--University of Kansas, Education, 1963.
Notch signaling regulates left–right asymmetry determination by inducing Nodal expression
Krebs, Luke T., Iwai, Naomi, Nonaka, Shigenori, Welsh, Ian C., Lan, Yu, Jiang, Rulang, ...
Generation of left–right asymmetry is an integral part of the establishment of the vertebrate body plan. Here we show that the Notch signaling pathway plays a primary role in the establishment of...
Notch signaling is essential for vascular morphogenesis in mice
Krebs, Luke T., Xue, Yingzi, Norton, Christine R., Shutter, John R., Maguire, Maureen, Sundberg, John P., ...
The Notch gene family encodes large transmembrane receptors that are components of an evolutionarily conserved intercellular signaling mechanism. To assess the role of the Notch4 gene, we generated...
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells
Domenga, Valérie, Fardoux, Peggy, Lacombe, Pierre, Monet, Marie, Maciazek, Jacqueline, Krebs, Luke T., ...
Formation of a fully functional artery proceeds through a multistep process. Here we show that Notch3 is required to generate functional arteries in mice by regulating arterial differentiation and...
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants
Krebs, Luke T., Shutter, John R., Tanigaki, Kenji, Honjo, Tasuku, Stark, Kevin L., Gridley, Thomas
The Notch signaling pathway is essential for embryonic vascular development in vertebrates. Here we show that mouse embryos heterozygous for a targeted mutation in the gene encoding the DLL4 ligand...
Notch signaling regulates left–right asymmetry determination by inducing Nodal expression
Krebs, Luke T., Iwai, Naomi, Nonaka, Shigenori, Welsh, Ian C., Lan, Yu, Jiang, Rulang, ...
Generation of left–right asymmetry is an integral part of the establishment of the vertebrate body plan. Here we show that the Notch signaling pathway plays a primary role in the establishment of...
Notch signaling is essential for vascular morphogenesis in mice
Krebs, Luke T., Xue, Yingzi, Norton, Christine R., Shutter, John R., Maguire, Maureen, Sundberg, John P., ...
The Notch gene family encodes large transmembrane receptors that are components of an evolutionarily conserved intercellular signaling mechanism. To assess the role of the Notch4 gene, we generated...
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells
Domenga, Valérie, Fardoux, Peggy, Lacombe, Pierre, Monet, Marie, Maciazek, Jacqueline, Krebs, Luke T., ...
Formation of a fully functional artery proceeds through a multistep process. Here we show that Notch3 is required to generate functional arteries in mice by regulating arterial differentiation and...
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants
Krebs, Luke T., Shutter, John R., Tanigaki, Kenji, Honjo, Tasuku, Stark, Kevin L., Gridley, Thomas
The Notch signaling pathway is essential for embryonic vascular development in vertebrates. Here we show that mouse embryos heterozygous for a targeted mutation in the gene encoding the DLL4 ligand...