Luquan Wang

Analysis of a human brain transcriptome map (2007)

Ping Qiu, Lawrence Benbow, Suxing Liu, Jonathan R Greene, Jonathan R Greene, Luquan Wang, ...

Background: Genome wide transcriptome maps can provide tools to identify candidate genes that are over-expressed or silenced in certain disease tissue and increase our understanding of the structure...

Genome wide in silicoSNP-tumor association analysis (2004)

Qiu, Ping, Wang, Luquan, Kostich, Mitch, Ding, Wei, Simon, Jason S, Greene, Jonathan R

Abstract Background Carcinogenesis occurs, at least in part, due to the accumulation of mutations in critical genes that control the mechanisms of cell proliferation, differentiation and death....

A Web-based design center for vector-based siRNA and siRNA cassette (2004)

Wang, Luquan, Mu, Forest Y.

To facilitate the designing process for vector-based siRNA and siRNA cassette, a tool set has been developed: siRNA target finder, siRNA construct builder, and siRNA sequence scrambler. The siRNA...

A Web-based design center for vector-based siRNA and siRNA cassette (2004)

Wang, Luquan, Mu, Forest Y.

Summary: To facilitate the designing process for vector-based siRNA and siRNA cassette, a tool set has been developed consisting of a siRNA target finder, a siRNA construct builder and a siRNA...

A Web-based design center for vector-based siRNA and siRNA cassette (2004)

Wang, Luquan, Mu, Forest Y.

To facilitate the designing process for vector-based siRNA and siRNA cassette, a tool set has been developed: siRNA target finder, siRNA construct builder, and siRNA sequence scrambler. The siRNA...

Domain-oriented functional analysis based on expression profiling (2002)

Ding, Wei, Wang, Luquan, Qiu, Ping, Kostich, Mitchel, Greene, Jonathan, Hernandez, Marco

Abstract Background Co-regulation of genes may imply involvement in similar biological processes or related function. Many clusters of co-regulated genes have been identified using microarray...

A reference database for tumor-related genes co-expressed with interleukin-8 using genome-scale in silico analysis (2002)

Benbow, Lawrence, Wang, Lynn, Laverty, Maureen, Liu, Suxing, Qiu, Ping, Bond, Richard W, ...

Abstract Background The EST database provides a rich resource for gene discovery and in silico expression analysis. We report a novel computational approach to identify co-expressed genes using EST...

Hepatitis C virus whole genome position weight matrix and robust primer design (2002)

Qiu, Ping, Cai, Xiao-Yan, Wang, Luquan, Greene, Jonathan R, Malcolm, Bruce

Abstract Background The high degree of sequence heterogeneity found in Hepatitis C virus (HCV) isolates, makes robust nucleic acid-based assays difficult to generate. Polymerase chain reaction based...

Human members of the eukaryotic protein kinase family (2002)

Kostich, Mitch, English, Jessie, Madison, Vincent, Gheyas, Ferdous, Wang, Luquan, Qiu, Ping, ...

Abstract Background Eukaryotic protein kinases (EPKs) constitute one of the largest recognized protein families represented in the human genome. EPKs, which are similar to each other in sequence,...

Analysis of a human brain transcriptome map (2002)

Qiu, Ping, Benbow, Lawrence, Liu, Suxing, Greene, Jonathan R, Wang, Luquan

Abstract Background Genome wide transcriptome maps can provide tools to identify candidate genes that are over-expressed or silenced in certain disease tissue and increase our understanding of the...

Microarray profile of differentially expressed genes in a monkey model of allergic asthma (2002)

Zou, Jun, Young, Simon, Zhu, Feng, Gheyas, Ferdous, Skeans, Susan, Wan, Yuntao, ...

Abstract Background Inhalation of Ascaris suum antigen by allergic monkeys causes an immediate bronchoconstriction and delayed allergic reaction, including a pulmonary inflammatory infiltrate. To...

Human members of the eukaryotic protein kinase family

Kostich, Mitch, English, Jessie, Madison, Vincent, Gheyas, Ferdous, Wang, Luquan, Qiu, Ping, ...

Publicly available genetic sequence data were searched for human sequences that potentially represent protein kinases, important players in virtually every signaling pathway. After removal of...

Genomic targets of the human c-Myc protein

Fernandez, Paula C., Frank, Scott R., Wang, Luquan, Schroeder, Marianne, Liu, Suxing, Greene, Jonathan, ...

The transcription factor Myc is induced by mitogenic signals and regulates downstream cellular responses. If overexpressed, Myc promotes malignant transformation. Myc modulates expression of diverse...

Analysis of the ERK1,2 transcriptome in mammary epithelial cells

Grill, Constance, Gheyas, Ferdous, Dayananth, Priya, Jin, Weihong, Ding, Wei, Qiu, Ping, ...

MAPK (mitogen-activated protein kinase) pathways constitute major regulators of cellular transcriptional programmes. We analysed the ERK1,2 (extracellular-signal-regulated kinase 1,2) transcriptome...

Human members of the eukaryotic protein kinase family

Kostich, Mitch, English, Jessie, Madison, Vincent, Gheyas, Ferdous, Wang, Luquan, Qiu, Ping, ...

Publicly available genetic sequence data were searched for human sequences that potentially represent protein kinases, important players in virtually every signaling pathway. After removal of...

Genomic targets of the human c-Myc protein

Fernandez, Paula C., Frank, Scott R., Wang, Luquan, Schroeder, Marianne, Liu, Suxing, Greene, Jonathan, ...

The transcription factor Myc is induced by mitogenic signals and regulates downstream cellular responses. If overexpressed, Myc promotes malignant transformation. Myc modulates expression of diverse...

Analysis of the ERK1,2 transcriptome in mammary epithelial cells

Grill, Constance, Gheyas, Ferdous, Dayananth, Priya, Jin, Weihong, Ding, Wei, Qiu, Ping, ...

MAPK (mitogen-activated protein kinase) pathways constitute major regulators of cellular transcriptional programmes. We analysed the ERK1,2 (extracellular-signal-regulated kinase 1,2) transcriptome...