Polymorphisms of the SIPA1gene and sporadic breast cancer susceptibility (2009)
Hsieh, Szu-Min, Smith, Robert A, Lintell, Nicholas A, Hunter, Kent W, Griffiths, Lyn R
Abstract Background The novel breast cancer metastasis modulator gene signal-induced proliferation-associated 1 ( Sipa1 ) underlies the breast cancer metastasis efficiency modifier locus Mtes 1 and...
Investigation of Gamma-aminobutyric acid (GABA) A receptors genes and migraine susceptibility (2008)
Fernandez, Francesca, Esposito, Teresa, Lea, Rod A, Colson, Natalie J, Ciccodicola, Alfredo, Gianfrancesco, Fernando, ...
Abstract Background Migraine is a neurological disorder characterized by recurrent attacks of severe headache, affecting around 12% of Caucasian populations. It is well known that migraine has a...
Association analysis of chromosome 1 migraine candidate genes (2007)
Fernandez, Francesca, Curtain, Robert P, Colson, Natalie J, Ovcaric, Micky, MacMillan, John, Griffiths, Lyn R
Abstract Background Migraine with aura (MA) is a subtype of typical migraine. Migraine with aura (MA) also encompasses a rare severe subtype Familial Hemiplegic Migraine (FHM) with several known...
Tajouri, Lotti, Fernandez, Francesca, Tajouri, Sophie, Detriche, Geraldine, Szvetko, Attila, Colson, Natalie, ...
Multiple Sclerosis (MS) is a central nervous system (CNS) chronic inflammatory demyelinating disease leading to various neurological disabilities. The disorder is more prevalent for women with a...
Tajouri, Lotti, Fernandez, Francesca, Tajouri, Sophie, Detriche, Geraldine, Szvetko, Attila, Colson, Natalie, ...
Multiple Sclerosis (MS) is a central nervous system (CNS) chronic inflammatory demyelinating disease leading to various neurological disabilities. The disorder is more prevalent for women with a...
Tajouri, Lotti, Fernandez, Francesca, Tajouri, Sophie, Detriche, Geraldine, Szvetko, Attila, Colson, Natalie, ...
Multiple Sclerosis (MS) is a central nervous system (CNS) chronic inflammatory demyelinating disease leading to various neurological disabilities. The disorder is more prevalent for women with a...
Tajouri, Lotti, Martin, Virginie, Gasparini, Claudia, Ovcaric, Micky, Curtain, Rob, Lea, Rod A., ...
Multiple sclerosis (MS) is a chronic neurological disease characterized by central nervous system (CNS) inflammation and demyelination. The C677T substitution variant in the methylenetetrahydrofolate...
Tajouri, Lotti, Martin, Virginie, Gasparini, Claudia, Ovcaric, Micky, Curtain, Rob, Lea, Rod A., ...
Multiple sclerosis (MS) is a chronic neurological disease characterized by central nervous system (CNS) inflammation and demyelination. The C677T substitution variant in the methylenetetrahydrofolate...
Colson, Natalie J, Lea, Rod A, Quinlan, Sharon, Griffiths, Lyn R
Abstract Background We have previously reported an association between the estrogen receptor 1 (ESR1) gene exon 8 G594A polymorphism and migraine susceptibility in two independent Australian cohorts....
Haupt, Larisa M, Thompson, Erik W, Trezise, Ann EO, Irving, Rachel E, Irving, Michael G, Griffiths, Lyn R
Abstract Background Members of the matrix metalloproteinase (MMP) family of proteases are required for the degradation of the basement membrane and extracellular matrix in both normal and...
Tajouri, Lotti, Martin, Virginie, Gasparini, Claudia, Ovcaric, Micky, Curtain, Rob, Lea, Rod A., ...
Multiple sclerosis (MS) is a chronic neurological disease characterized by central nervous system (CNS) inflammation and demyelination. The C677T substitution variant in the methylenetetrahydrofolate...
Tajouri, Lotti, Martin, Virginie, Gasparini, Claudia, Ovcaric, Micky, Curtain, Rob, Lea, Rod A., ...
Multiple sclerosis (MS) is a chronic neurological disease characterized by central nervous system (CNS) inflammation and demyelination. The C677T substitution variant in the methylenetetrahydrofolate...
Genetic polymorphisms in DPF3associated with risk of breast cancer and lymph node metastases (2005)
Hoyal, Carolyn R, Kammerer, Stefan, Roth, Richard B, Reneland, Richard, Marnellos, George, Kiechle, Marion, ...
Abstract Background Several studies have identified rare genetic variations responsible for many cases of familial breast cancer but their contribution to total breast cancer incidence is relatively...
Tajouri, Lotti, Ovcaric, Micky, Curtain, Rob, Johnson, Matthew P., Griffiths, Lyn R., Csurhes, Peter, ...
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) resulting in accumulating neurological disability. The disorder is more prevalent at higher...
Tajouri, Lotti, Ovcaric, Micky, Curtain, Rob, Johnson, Matthew P., Griffiths, Lyn R., Csurhes, Peter, ...
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) resulting in accumulating neurological disability. The disorder is more prevalent at higher...
Tajouri, Lotti, Ovcaric, Micky, Curtain, Rob, Johnson, Matthew P., Griffiths, Lyn R., Csurhes, Peter, ...
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) resulting in accumulating neurological disability. The disorder is more prevalent at higher...
Tajouri, Lotti, Ovcaric, Micky, Curtain, Rob, Johnson, Matthew P., Griffiths, Lyn R., Csurhes, Peter, ...
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) resulting in accumulating neurological disability. The disorder is more prevalent at higher...
Tajouri, Lotti, Ovcaric, Micky, Curtain, Rob, Johnson, Matthew P., Griffiths, Lyn R., Csurhes, Peter, ...
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) resulting in accumulating neurological disability. The disorder is more prevalent at higher...
Selvey, Saxon, Haupt, Larisa M, Thompson, Erik W, Matthaei, Klaus I, Irving, Michael G, Griffiths, Lyn R
Abstract Background Matrix metalloproteinases (MMPs) are central to degradation of the extracellular matrix and basement membrane during both normal and carcinogenic tissue remodeling. MT1-MMP...
Tajouri, Lotti, Martin, Virginie, Ovcaric, Micky, Curtain, Rob P., Lea, Rod A., Csurhes, Peter, ...
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) affecting most commonly the Caucasian population. Nitric oxide (NO) is a biological signaling and...
Tajouri, Lotti, Martin, Virginie, Ovcaric, Micky, Curtain, Rob P., Lea, Rod A., Csurhes, Peter, ...
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) affecting most commonly the Caucasian population. Nitric oxide (NO) is a biological signaling and...
Tajouri, Lotti, Ferreira, Linda, Ovcaric, Micky, Curtain, Rob, Lea, Rod, Csurhes, Peter A., ...
Multiple Sclerosis (MS) is a chronic neurological disease characterized by demyelination associated with infiltrating white blood cells in the central nervous system (CNS). Nitric oxide synthases...
Tajouri, Lotti, Ferreira, Linda, Ovcaric, Micky, Curtain, Rob, Lea, Rod, Csurhes, Peter A., ...
Multiple Sclerosis (MS) is a chronic neurological disease characterized by demyelination associated with infiltrating white blood cells in the central nervous system (CNS). Nitric oxide synthases...
Lea, Rod A, Ovcaric, Micky, Sundholm, James, MacMillan, John, Griffiths, Lyn R
Abstract Background The C677T variant in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with increased levels of circulating homocysteine and is a mild risk factor for vascular...
Tajouri, Lotti, Ferreira, Linda, Ovcaric, Micky, Curtain, Rob, Lea, Rod, Csurhes, Peter A., ...
Multiple Sclerosis (MS) is a chronic neurological disease characterized by demyelination associated with infiltrating white blood cells in the central nervous system (CNS). Nitric oxide synthases...
Tajouri, Lotti, Martin, Virginie, Ovcaric, Micky, Curtain, Rob P., Lea, Rod A., Csurhes, Peter, ...
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) affecting most commonly the Caucasian population. Nitric oxide (NO) is a biological signaling and...
Tajouri, Lotti, Ferreira, Linda, Ovcaric, Micky, Curtain, Rob, Lea, Rod, Csurhes, Peter A., ...
Multiple Sclerosis (MS) is a chronic neurological disease characterized by demyelination associated with infiltrating white blood cells in the central nervous system (CNS). Nitric oxide synthases...
Tajouri, Lotti, Martin, Virginie, Ovcaric, Micky, Curtain, Rob P., Lea, Rod A., Csurhes, Peter, ...
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) affecting most commonly the Caucasian population. Nitric oxide (NO) is a biological signaling and...
Johnson, Matthew P., Haupt, Larisa M., Griffiths, Lyn R.
With an increased emphasis on genotyping of single nucleotide polymorphisms (SNPs) in disease association studies, the genotyping platform of choice is constantly evolving. In addition, the...
Ashton, Kevin J., Weinstein, Stephen R., Maguire, David J., Griffiths, Lyn R.
Objective To identify chromosomal copy numbers of frequent genetic aberrations within squamous cell carcinomas (SCCs) and solar keratoses (SKs), and provide further evidence to support or challenge...
Smith, Robert A, Lea, Rod A, Curran, Joanne E, Weinstein, Stephen R, Griffiths, Lyn R
Background Previous studies in our laboratory have shown associations of specific nuclear receptor gene variants with sporadic breast cancer. In order to investigate these findings further, we...
Mellick, Albert S., Blackmore, Daneia, Weinstein, Stephen R., Griffiths, Lyn R.
To examine matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinases (TIMP) mRNA levels in archival breast cancer biopsies, we employed microdissection to separate tumour tissue from...
Smith, Robert A, Lea, Rod A, Curran, Joanne E, Weinstein, Stephen R, Griffiths, Lyn R
Abstract Background Previous studies in our laboratory have shown associations of specific nuclear receptor gene variants with sporadic breast cancer. In order to investigate these findings further,...
Investigation of glutathione S-transferase zeta and the development of sporadic breast cancer (2001)
Smith, Robert A, Curran, Joanne E, Weinstein, Stephen R, Griffiths, Lyn R
Abstract Background Certain genes from the glutathione S -transferase superfamily have been associated with several cancer types. It was the objective of this study to determine whether alleles of...
Investigation of glutathione S-transferase zeta and the development of sporadic breast cancer
Smith, Robert A, Curran, Joanne E, Weinstein, Stephen R, Griffiths, Lyn R
Johnson, Matthew P., Haupt, Larisa M., Griffiths, Lyn R.
With an increased emphasis on genotyping of single nucleotide polymorphisms (SNPs) in disease association studies, the genotyping platform of choice is constantly evolving. In addition, the...
Selvey, Saxon, Haupt, Larisa M, Thompson, Erik W, Matthaei, Klaus I, Irving, Michael G, Griffiths, Lyn R
Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility
Kammerer, Stefan, Roth, Richard B., Hoyal, Carolyn R., Reneland, Richard, Marnellos, George, Kiechle, Marion, ...
The development of breast cancer is a complex process that involves multiple genes at many stages, from initial cell cycle dysregulation to disease progression. To identify genetic variations that...
Genetic polymorphisms in DPF3 associated with risk of breast cancer and lymph node metastases
Hoyal, Carolyn R, Kammerer, Stefan, Roth, Richard B, Reneland, Richard, Marnellos, George, Kiechle, Marion, ...
Haupt, Larisa M, Thompson, Erik W, Trezise, Ann EO, Irving, Rachel E, Irving, Michael G, Griffiths, Lyn R
Investigation of glutathione S-transferase zeta and the development of sporadic breast cancer
Smith, Robert A, Curran, Joanne E, Weinstein, Stephen R, Griffiths, Lyn R
Johnson, Matthew P., Haupt, Larisa M., Griffiths, Lyn R.
With an increased emphasis on genotyping of single nucleotide polymorphisms (SNPs) in disease association studies, the genotyping platform of choice is constantly evolving. In addition, the...
Selvey, Saxon, Haupt, Larisa M, Thompson, Erik W, Matthaei, Klaus I, Irving, Michael G, Griffiths, Lyn R
Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility
Kammerer, Stefan, Roth, Richard B., Hoyal, Carolyn R., Reneland, Richard, Marnellos, George, Kiechle, Marion, ...
The development of breast cancer is a complex process that involves multiple genes at many stages, from initial cell cycle dysregulation to disease progression. To identify genetic variations that...
Genetic polymorphisms in DPF3 associated with risk of breast cancer and lymph node metastases
Hoyal, Carolyn R, Kammerer, Stefan, Roth, Richard B, Reneland, Richard, Marnellos, George, Kiechle, Marion, ...
Haupt, Larisa M, Thompson, Erik W, Trezise, Ann EO, Irving, Rachel E, Irving, Michael G, Griffiths, Lyn R
Association analysis of chromosome 1 migraine candidate genes
Fernandez, Francesca, Curtain, Robert P, Colson, Natalie J, Ovcaric, Micky, MacMillan, John, Griffiths, Lyn R
Gene Expression Studies in Multiple Sclerosis
Tajouri, Lotti, Fernandez, Francesca, Griffiths, Lyn R
Multiple sclerosis (MS) is a serious neurological disorder affecting young Caucasian individuals, usually with an age of onset at 18 to 40 years old. Females account for approximately 60× of MS...