Lynn D. Haynes

Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant β2-microglobulin gene

Wani, Manzoor A., Haynes, Lynn D., Kim, Jonghan, Bronson, C. L., Chaudhury, Chaity, Mohanty, Sudhasri, ...

Two siblings, products of a consanguineous marriage, were markedly deficient in both albumin and IgG because of rapid degradation of these proteins, suggesting a lack of the neonatal Fc receptor,...

Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant β2-microglobulin gene

Wani, Manzoor A., Haynes, Lynn D., Kim, Jonghan, Bronson, C. L., Chaudhury, Chaity, Mohanty, Sudhasri, ...

Two siblings, products of a consanguineous marriage, were markedly deficient in both albumin and IgG because of rapid degradation of these proteins, suggesting a lack of the neonatal Fc receptor,...

IL-17–dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants

Burlingham, William J., Love, Robert B., Jankowska-Gan, Ewa, Haynes, Lynn D., Xu, Qingyong, Bobadilla, Joseph L., ...

Bronchiolitis obliterans syndrome (BOS), a process of fibro-obliterative occlusion of the small airways in the transplanted lung, is the most common cause of lung transplant failure. We tested the...

Th-17, Monokines, Collagen Type V, and Primary Graft Dysfunction in Lung Transplantation

Bobadilla, Joseph L., Love, Robert B., Jankowska-Gan, Ewa, Xu, Qingyong, Haynes, Lynn D., Braun, Ruedi K., ...

Rationale: The pathogenesis of primary graft dysfunction (PGD), a serious complication of lung transplantation, is poorly understood. Human studies and rodent models have shown that collagen type V...