Lynn Doucette-Stamm

A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity (2008)

Martinez, Natalia J., Ow, Maria C., Barrasa, M. Inmaculada, Hammell, Molly, Sequerra, Reynaldo, Doucette-Stamm, Lynn, ...

MicroRNAs (miRNAs) and transcription factors (TFs) are primary metazoan gene regulators. Whereas much attention has focused on finding the targets of both miRNAs and TFs, the transcriptional networks...

A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity (2008)

Martinez, Natalia J., Ow, Maria C., Barrasa, M. Inmaculada, Hammell, Molly, Sequerra, Reynaldo, Doucette-Stamm, Lynn, ...

MicroRNAs (miRNAs) and transcription factors (TFs) are primary metazoan gene regulators. Whereas much attention has focused on finding the targets of both miRNAs and TFs, the transcriptional networks...

Multiplex Sequencing of 1.5 Mb of the Mycobacterium leprae Genome (2007)

Douglas R. Smith, Peter Richterich, Marc Rubenfield, Philip W. Rice, Kathleen Falls, Joan Imrich, ...

The nucleotide sequence of 1.5 Mb of genomic DNA from Mycobacterium leprae was determined using computer-assisted multiplex sequencing technology. This brings the 2.8-Mb M. leprae genome sequence to...

Transcription factor modularity in a gene-centered C. elegans core neuronal protein-DNA interaction network (2007)

Vermeirssen, Vanessa, Barrasa, M. Inmaculada, Hidalgo, César A., Babon, Jenny Aurielle B., Sequerra, Reynaldo, Doucette-Stamm, Lynn, ...

Transcription regulatory networks play a pivotal role in the development, function, and pathology of metazoan organisms. Such networks are comprised of protein–DNA interactions between...

Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping (2007)

Vermeirssen, Vanessa, Deplancke, Bart, Barrasa, M. Inmaculada, Reece-Hoyes, John S., Arda, H. Efsun, Grove, Christian A., ...

Yeast one-hybrid (Y1H) assays provide a gene-centered method for the identification of interactions between gene promoters and regulatory transcription factors (TFs). To date, Y1H assays have...

Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping (2007)

Vermeirssen, Vanessa, Deplancke, Bart, Barrasa, M. Inmaculada, Reece-Hoyes, John S., Arda, H. Efsun, Grove, Christian A., ...

Yeast one-hybrid (Y1H) assays provide a gene-centered method for the identification of interactions between gene promoters and regulatory transcription factors (TFs). To date, Y1H assays have...

Transcription factor modularity in a gene-centered C. elegans core neuronal protein-DNA interaction network (2007)

Vermeirssen, Vanessa, Barrasa, M. Inmaculada, Hidalgo, Cesar A., Babon, Jenny Aurielle B., Sequerra, Reynaldo, Doucette-Stamm, Lynn, ...

Transcription regulatory networks play a pivotal role in the development, function, and pathology of metazoan organisms. Such networks are comprised of protein-DNA interactions between transcription...

A gene-centered C. elegans protein-DNA interaction network (2006)

Deplancke, Bart, Mukhopadhyay, Arnab, Ao, Wanyuan, Elewa, Ahmed M., Grove, Christian A., Martinez, Natalia J., ...

Transcription regulatory networks consist of physical and functional interactions between transcription factors (TFs) and their target genes. The systematic mapping of TF-target gene interactions has...

C. elegans ORFeome Version 3.1: Increasing the Coverage of ORFeome Resources With Improved Gene Predictions (2004)

Lamesch, Philippe, Milstein, Stuart, Hao, Tong, Rosenberg, Jennifer, Li, Ning, Sequerra, Reynaldo, ...

The first version of the Caenorhabditis elegans ORFeome cloning project, based on release WS9 of Wormbase (August 1999), provided experimental verifications for ∼55% of predicted protein-encoding...

Human ORFeome Version 1.1: A Platform for Reverse Proteomics (2004)

Rual, Jean-François, Hirozane-Kishikawa, Tomoko, Hao, Tong, Bertin, Nicolas, Li, Siming, Dricot, Amélie, ...

The advent of systems biology necessitates the cloning of nearly entire sets of protein-encoding open reading frames (ORFs), or ORFeomes, to allow functional studies of the corresponding proteomes....

A First Version of the Caenorhabditis elegans Promoterome (2004)

Dupuy, Denis, Li, Qian-Ru, Deplancke, Bart, Boxem, Mike, Hao, Tong, Lamesch, Philippe, ...

An important aspect of the development of systems biology approaches in metazoans is the characterization of expression patterns of nearly all genes predicted from genome sequences. Such...

Generation of the Brucella melitensis ORFeome Version 1.1 (2004)

Dricot, Amélie, Rual, Jean-François, Lamesch, Philippe, Bertin, Nicolas, Dupuy, Denis, Hao, Tong, ...

The bacteria of the Brucella genus are responsible for a worldwide zoonosis called brucellosis. They belong to the α-proteobacteria group, as many other bacteria that live in close association with...

Protein interaction mapping on a functional shotgun sequence of Rickettsia sibirica (2004)

Malek, Joel A., Wierzbowski, Jamey M., Tao, Wei, Bosak, Stephanie A., Saranga, David J., Doucette-Stamm, Lynn, ...

Protein interaction maps can reveal novel pathways and functional complexes, allowing ‘guilt by association’ annotation of uncharacterized proteins. To address the need for large‐scale...

Exo-Proofreading, A Versatile SNP Scoring Technology (2003)

Cahill, Patrick, Bakis, Michele, Hurley, James, Kamath, Veena, Nielsen, William, Weymouth, Dina, ...

We report the validation of a new assay for typing single nucleotide polymorphisms (SNPs) that takes advantage of the 3′-to-5′ exonuclease proofreading activity of many DNA polymerases. The assay...

Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum (2001)

Jörk Nölling, Gary Breton, Marina V. Omelchenko, Kira S. Makarova, Qiandong Zeng, Rene Gibson, ...

The genome sequence of the solvent-producing bacterium Clostridium acetobutylicum ATCC 824 has been determined by the shotgun approach. The genome consists of a 3.94-Mb chromosome and a 192-kb...

Genome Sequence and Comparative Analysis of the Solvent-Producing Bacterium Clostridium acetobutylicum

Nölling, Jörk, Breton, Gary, Omelchenko, Marina V., Makarova, Kira S., Zeng, Qiandong, Gibson, Rene, ...

The genome sequence of the solvent-producing bacterium Clostridium acetobutylicum ATCC 824 has been determined by the shotgun approach. The genome consists of a 3.94-Mb chromosome and a 192-kb...

Protein interaction mapping on a functional shotgun sequence of Rickettsia sibirica

Malek, Joel A., Wierzbowski, Jamey M., Tao, Wei, Bosak, Stephanie A., Saranga, David J., Doucette-Stamm, Lynn, ...

Protein interaction maps can reveal novel pathways and functional complexes, allowing ‘guilt by association’ annotation of uncharacterized proteins. To address the need for large-scale protein...

Exo-Proofreading, A Versatile SNP Scoring Technology

Cahill, Patrick, Bakis, Michele, Hurley, James, Kamath, Veena, Nielsen, William, Weymouth, Dina, ...

We report the validation of a new assay for typing single nucleotide polymorphisms (SNPs) that takes advantage of the 3′-to-5′ exonuclease proofreading activity of many DNA polymerases. The assay...

C. elegans ORFeome Version 3.1: Increasing the Coverage of ORFeome Resources With Improved Gene Predictions

Lamesch, Philippe, Milstein, Stuart, Hao, Tong, Rosenberg, Jennifer, Li, Ning, Sequerra, Reynaldo, ...

The first version of the Caenorhabditis elegans ORFeome cloning project, based on release WS9 of Wormbase (August 1999), provided experimental verifications for ∼55% of predicted protein-encoding...

Human ORFeome Version 1.1: A Platform for Reverse Proteomics

Rual, Jean-François, Hirozane-Kishikawa, Tomoko, Hao, Tong, Bertin, Nicolas, Li, Siming, Dricot, Amélie, ...

The advent of systems biology necessitates the cloning of nearly entire sets of protein-encoding open reading frames (ORFs), or ORFeomes, to allow functional studies of the corresponding proteomes....

A First Version of the Caenorhabditis elegans Promoterome

Dupuy, Denis, Li, Qian-Ru, Deplancke, Bart, Boxem, Mike, Hao, Tong, Lamesch, Philippe, ...

An important aspect of the development of systems biology approaches in metazoans is the characterization of expression patterns of nearly all genes predicted from genome sequences. Such...

Generation of the Brucella melitensis ORFeome Version 1.1

Dricot, Amélie, Rual, Jean-François, Lamesch, Philippe, Bertin, Nicolas, Dupuy, Denis, Hao, Tong, ...

The bacteria of the Brucella genus are responsible for a worldwide zoonosis called brucellosis. They belong to the α-proteobacteria group, as many other bacteria that live in close association with...

A protein–protein interaction map of the Caenorhabditis elegans 26S proteasome

Davy, Anne, Bello, Paul, Thierry-Mieg, Nicolas, Vaglio, Philippe, Hitti, Joseph, Doucette-Stamm, Lynn, ...

The ubiquitin-proteasome proteolytic pathway is pivotal in most biological processes. Despite a great level of information available for the eukaryotic 26S proteasome—the protease responsible for...

Genome Sequence and Comparative Analysis of the Solvent-Producing Bacterium Clostridium acetobutylicum

Nölling, Jörk, Breton, Gary, Omelchenko, Marina V., Makarova, Kira S., Zeng, Qiandong, Gibson, Rene, ...

The genome sequence of the solvent-producing bacterium Clostridium acetobutylicum ATCC 824 has been determined by the shotgun approach. The genome consists of a 3.94-Mb chromosome and a 192-kb...

Protein interaction mapping on a functional shotgun sequence of Rickettsia sibirica

Malek, Joel A., Wierzbowski, Jamey M., Tao, Wei, Bosak, Stephanie A., Saranga, David J., Doucette-Stamm, Lynn, ...

Protein interaction maps can reveal novel pathways and functional complexes, allowing ‘guilt by association’ annotation of uncharacterized proteins. To address the need for large-scale protein...

Exo-Proofreading, A Versatile SNP Scoring Technology

Cahill, Patrick, Bakis, Michele, Hurley, James, Kamath, Veena, Nielsen, William, Weymouth, Dina, ...

We report the validation of a new assay for typing single nucleotide polymorphisms (SNPs) that takes advantage of the 3′-to-5′ exonuclease proofreading activity of many DNA polymerases. The assay...

C. elegans ORFeome Version 3.1: Increasing the Coverage of ORFeome Resources With Improved Gene Predictions

Lamesch, Philippe, Milstein, Stuart, Hao, Tong, Rosenberg, Jennifer, Li, Ning, Sequerra, Reynaldo, ...

The first version of the Caenorhabditis elegans ORFeome cloning project, based on release WS9 of Wormbase (August 1999), provided experimental verifications for ∼55% of predicted protein-encoding...

Human ORFeome Version 1.1: A Platform for Reverse Proteomics

Rual, Jean-François, Hirozane-Kishikawa, Tomoko, Hao, Tong, Bertin, Nicolas, Li, Siming, Dricot, Amélie, ...

The advent of systems biology necessitates the cloning of nearly entire sets of protein-encoding open reading frames (ORFs), or ORFeomes, to allow functional studies of the corresponding proteomes....

A First Version of the Caenorhabditis elegans Promoterome

Dupuy, Denis, Li, Qian-Ru, Deplancke, Bart, Boxem, Mike, Hao, Tong, Lamesch, Philippe, ...

An important aspect of the development of systems biology approaches in metazoans is the characterization of expression patterns of nearly all genes predicted from genome sequences. Such...

Generation of the Brucella melitensis ORFeome Version 1.1

Dricot, Amélie, Rual, Jean-François, Lamesch, Philippe, Bertin, Nicolas, Dupuy, Denis, Hao, Tong, ...

The bacteria of the Brucella genus are responsible for a worldwide zoonosis called brucellosis. They belong to the α-proteobacteria group, as many other bacteria that live in close association with...

A protein–protein interaction map of the Caenorhabditis elegans 26S proteasome

Davy, Anne, Bello, Paul, Thierry-Mieg, Nicolas, Vaglio, Philippe, Hitti, Joseph, Doucette-Stamm, Lynn, ...

The ubiquitin-proteasome proteolytic pathway is pivotal in most biological processes. Despite a great level of information available for the eukaryotic 26S proteasome—the protease responsible for...

Transcription factor modularity in a gene-centered C. elegans core neuronal protein–DNA interaction network

Vermeirssen, Vanessa, Barrasa, M. Inmaculada, Hidalgo, César A., Babon, Jenny Aurielle B., Sequerra, Reynaldo, Doucette-Stamm, Lynn, ...

Transcription regulatory networks play a pivotal role in the development, function, and pathology of metazoan organisms. Such networks are comprised of protein–DNA interactions between...

A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity

Martinez, Natalia J., Ow, Maria C., Barrasa, M. Inmaculada, Hammell, Molly, Sequerra, Reynaldo, Doucette-Stamm, Lynn, ...

MicroRNAs (miRNAs) and transcription factors (TFs) are primary metazoan gene regulators. Whereas much attention has focused on finding the targets of both miRNAs and TFs, the transcriptional networks...