Lynn E. Delisi

Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation (2009)

Martin, Maureen V, Rollins, Brandi, Sequeira, P Adolfo, Mesén, Andrea, Byerley, William, Stein, Richard, ...

Abstract Background The purpose of this study was to examine the effects of glucose reduction stress on lymphoblastic cell line (LCL) gene expression in subjects with schizophrenia compared to...

Searching for the true genetic vulnerability for schizophrenia (2009)

DeLisi, Lynn E

Abstract The search for a genetic basis for schizophrenia has taken a new turn recently with the publication of three reports of various rare copy-number variations that are associated with...

A Geometric Morphometric Assessment of Change in Midline Brain Structural Shape following a First Episode of Schizophrenia (2007)

Waleed S. Gharaibeh, F. James Rohlf, Dennis E. Slice, Lynn E. Delisi

Background: Previous reports indicate that brain structural abnormalities may be progressive in some patients with schizophrenia. Our study was designed to determine deviations in the shape of...

A preliminary DTI study showing no brain structural change associated with adolescent cannabis use (2006)

DeLisi, Lynn E, Bertisch, Hilary C, Szulc, Kamila U, Majcher, Magda, Brown, Kyle, Bappal, Arthika, ...

Abstract Analyses were performed on brain MRI scans from individuals who were frequent cannabis users (N = 10; 9 males, 1 female, mean age 21.1 ± 2.9, range: 18–27) in adolescence and similar age...

Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia (2003)

Lewis, Cathryn M, Levinson, Douglas F, Wise, Lesley H, DeLisi, Lynn E, Straub, Richard E, Hovatta, Iiris, ...

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Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2p12-q11 (2003)

Francks, Clyde, DeLisi, Lynn E., Shaw, Sarah H., Fisher, Simon E., Richardson, Alex J., Stein, John F., ...

Schizophrenia and non-right-handedness are moderately associated, and both traits are often accompanied by abnormalities of asymmetrical brain morphology or function. We have found linkage previously...

Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2p12-q11 (2003)

Francks, Clyde, DeLisi, Lynn E., Shaw, Sarah H., Fisher, Simon E., Richardson, Alex J., Stein, John F., ...

Schizophrenia and non-right-handedness are moderately associated, and both traits are often accompanied by abnormalities of asymmetrical brain morphology or function. We have found linkage previously...

Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2p12-q11 (2003)

Francks, Clyde, DeLisi, Lynn E., Shaw, Sarah H., Fisher, Simon E., Richardson, Alex J., Stein, John F., ...

Schizophrenia and non-right-handedness are moderately associated, and both traits are often accompanied by abnormalities of asymmetrical brain morphology or function. We have found linkage previously...

Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2p12-q11 (2003)

Francks, Clyde, DeLisi, Lynn E., Shaw, Sarah H., Fisher, Simon E., Richardson, Alex J., Stein, John F., ...

Schizophrenia and non-right-handedness are moderately associated, and both traits are often accompanied by abnormalities of asymmetrical brain morphology or function. We have found linkage previously...

Speech Disorder in Schizophrenia: Review of the Literature and Exploration of Its Relation to the Uniquely Human Capacity for Language (2001)

DeLisi, Lynn E.

The language capacity of modern humans is thought by some to be clearly distinct from that of nonhuman primates (Bickerton 1990). Crow (1997, 1998a) has proposed that a disturbance in the uniquely...

Quantification of cerebral grey and white matter asymmetry from MRI (1999)

Frederik Maes, Koen Van Leemput, Lynn E. DeLisi, Dirk Vandermeulen, Paul Suetens

We present a completely automated procedure for measuring left and right hemispheric asymmetry in cerebral grey and white matter volumes from MR images using a chain of state-of-the-art image...

Anomalous Cerebral Asymmetry and Language Processing in Schizophrenia (1997)

DeLisi, Lynn E., Sakuma, Michael, Kushner, Maureen, Finer, Daniel L., Hoff, Anne L., Crow, Timothy J.

Reversal or reduction of normal structural cerebral asymmetries may be related to the pathogenesis of schizophrenia, but this relationship remains controversial. We review the literature and describe...

The Significance of Age of Onset for Schizophrenia (1992)

DeLisi, Lynn E.

Age of onset is the single most important characteristic of schizophrenia that could yield clues to its origin. To identify the age of onset, however, the onset of the pathological process must be...

Anomalous Lateral Sulcus Asymmetry and Cognitive Function in First-episode Schizophrenia (1992)

Hoff, Anne L., Riordan, Henry, O'Donnell, Donald, Stritzke, Peter, Neale, Chance, Boccio, Angela, ...

This study examines the cognitive functioning of first-episode schizophreniform patients within several weeks of hospitalization and at 2 years into the illness. Differences between patients and...

Evidence for a Sex Chromosome Locus for Schizophrenia (1989)

DeLisi, Lynn E., Crow, Timothy J.

The sex chromosomes are strong candidates for a genetic locus for schizophrenia and the affective psychoses. Gender differences in the clinical expression of illness and familial risks, concordance...

Physical Mapping, Linkage Analysis of a Putative Schizophrenia Locus on Chromosome 5q (1989)

Kaufmann, Charles A., DeLisi, Lynn E., Lehner, Thomas, Gilliam, T. Conard

Two recent studies have suggested that a schizophrenia susceptibility locus may lie on the proximal long arm of chromosome 5. Partial trisomy of a 20–30 centimorgan region of chromosome 5...

Perinatal Complications and Reduced Size of Brain Limbic Structures in Familial Schizophrenia (1988)

DeLisi, Lynn E., Dauphinais, I. Deborah, Gershon, Elliot S.

Both genetic and nongenetic risk factors for schizophrenia have been described. Specifically, perinatal complications have been suggested as a factor in the later development of schizophrenia. These...

A preliminary DTI study showing no brain structural change associated with adolescent cannabis use

DeLisi, Lynn E, Bertisch, Hilary C, Szulc, Kamila U, Majcher, Magda, Brown, Kyle, Bappal, Arthika, ...

Analyses were performed on brain MRI scans from individuals who were frequent cannabis users (N = 10; 9 males, 1 female, mean age 21.1 ± 2.9, range: 18–27) in adolescence and similar age and sex...

Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part II: Schizophrenia

Lewis, Cathryn M., Levinson, Douglas F., Wise, Lesley H., DeLisi, Lynn E., Straub, Richard E., Hovatta, Iiris, ...

Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to siblings of probands. Replication has been inconsistent for reports of significant genetic linkage. To...

A preliminary DTI study showing no brain structural change associated with adolescent cannabis use

DeLisi, Lynn E, Bertisch, Hilary C, Szulc, Kamila U, Majcher, Magda, Brown, Kyle, Bappal, Arthika, ...

Analyses were performed on brain MRI scans from individuals who were frequent cannabis users (N = 10; 9 males, 1 female, mean age 21.1 ± 2.9, range: 18–27) in adolescence and similar age and sex...

The Concept of Progressive Brain Change in Schizophrenia: Implications for Understanding Schizophrenia

DeLisi, Lynn E.

Kraepelin originally defined dementia praecox as a progressive brain disease, although this concept has received various degrees of acceptance and rejection over the years since his famous published...

Searching for the true genetic vulnerability for schizophrenia

DeLisi, Lynn E

The search for a genetic basis for schizophrenia has taken a new turn recently with the publication of three reports of various rare copy-number variations that are associated with schizophrenia....