M. A. Hofman

Increased arginine vasopressin mRNA expression in the human hypothalamus in depression: A preliminary report (2006)

Meynen, G., Unmehopa, U.A., Heerikhuize, J.J. Van, Hofman, M.A., Swaab, D.F., Hoogendijk, W.J.G.

Background: Elevated arginine vasopressin (AVP) plasma levels have been observed in major depression, particularly in relation to the melancholic subtype. Two hypothalamic structures produce plasma...

Living by the clock: The circadian pacemaker in older people (2006)

Hofman, M.A., Swaab, D.F.

The suprachiasmatic nucleus (SCN) of the hypothalamus is considered to be a critical component of a neural oscillator system implicated in the timing of a wide variety of biological processes. The...

The seventeenth C.U. Ariëns Kappers lecture: an introduction [ch 13] (2006)

Hofman, M.A., Swaab, D.F.

Hypothalamic integration of energy metabolism [Proceedings of the international summer school of brain research, held at the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands 29 August- 1 September 2005] (2006)

Kalsbeek, A., Fliers, E., Hofman, M.A., Swaab, D.F., Buijs, R.M.

ApoE epsilon4 genotype is accompanied by lower metabolic activity in nucleus basalis of Meynert neurons in Alzheimer patients and controls as indicated by the size of the Golgi apparatus (2004)

Dubelaar, E.J., Verwer, R.W., Hofman, M.A., Heerikhuize, J.J. Van, Ravid, R., Swaab, D.F.

Neuroplasticity in the human hypothalamus during aging (2004)

Hofman, M.A., Swaab, D.F.

Living by the clock: the circadian pacemaker in older people (2004)

Hofman, M.A., Swaab, D.F.

Neuroplasticity in the human hypothalamus during ageing (2004)

Hofman, M.A., Swaab, D.F.

ApoE epsilon 4 genotype is accompanied by lower metabolic activity in nucleus basalis of Meynert neurons in Alzheimer patients and controls as indicated by the size of the Golgi apparatus (2004)

Dubelaar, E.J.G., Verwer, R.W.H., Hofman, M.A., Heerikhuize, J.J. Van, Ravid, R., Swaab, D.F.

Alterations in the circadian rhythm of salivary melatonin begin during middle-age (2003)

Zhou, J.N., Llu, R.Y., Heerikhuize, J.J. Van, Hofman, M.A., Swaab, D.F.

Early neuropathological Alzheimer changes in aged controls accompanied by decreased cerebrospinal fluid melatonin levels (2003)

Zhou, J.N., Liu, R.Y., Kamphorst, W., Hofman, M.A., Swaab, D.F.

Early neuropathological Alzheimer's changes in aged individuals are accompanied by decreased cerebrospinal fluid melatonin levels (2003)

Zhou, J.N., Liu, R-Y., Kamphorst, W., Hofman, M.A., Swaab, D.F.

Sex differences in the hypothalamus in the different stages of human life (2003)

Swaab, D.F., Chung, W.C.J., Kruijver, F.P.M., Hofman, M.A., Hestiantoro, A.

Alterations in the circadian rhythm of salivary melatonin begin during middle-age (2003)

Zhou, J.N., Liu, R-Y., Heerikhuize, J. Van, Hofman, M.A., Swaab, D.F.

Sexual differentiation of the human hypothalamus (2002)

Swaab, D.F., Chung, W.C., Kruijver, F.P.M., Hofman, M.A., Ishunina, T.A.

A brain for all seasons: cellular and molecular mechanisms of photoperiodic plasticity (2002)

Hofman, M.A., Swaab, D.F.

Sexual differentiation of the human hypothalamus (2002)

Swaab, D.F., Chung, W.C.J., Kruijver, F.P.M., Hofman, M.A., Ishunina, T.A.

The fifteenth C.U. Ariëns Kappers Lecture. An Introduction (2002)

Swaab, D.F., Hofman, M.A.

Brain aging and Alzheimer's disease; use it or lose it (2002)

Swaab, D.F., Dubelaar, E.J.G., Hofman, M.A., Scherder, E.J.A., Verwer, R.W.H.

Sexual differentiation of the human hypothalamus (2002)

Swaab, D.F., Chun, W.C., Kruijver, F.P.M., Hofman, M.A., Ishunina, T.A.

The Fifteenth C.U. Ariens Kappers lecture - An introduction (2002)

Swaab, D.F., Hofman, M.A.

A brain for all seasons: cellular and molecular mechanisms of photoperiodic plasticity (2002)

Hofman, M.A., Swaab, D.F.

A brain for all seasons: cellular and molecular mechanisms of photoperiodic plasticity (2002)

Hofman, M.A., Swaab, D.F.

The fifteenth C.U. Ariens Kappers lecture. An introduction [ch. 22] (2002)

Swaab, D.F., Hofman, M.A.

Brain ageing and Alzheimer's disease; use it or lose it [ch. 20] (2002)

Swaab, D.F., Dubelaar, E.J.G., Hofman, M.A., Scherder, E.J.A., Verwer, R.W.H.

Structural and functional sex differences in the human hypothalamus (2001)

Swaab, D.F., Chung, W.C.J., Kruijver, F.P.M., Hofman, M.A., Ushunina, T.A.

Alterations in arginine vasopressin neurons in the suprachiasmatic nucleus in depression (2001)

Zhou, J.N., Riemersma, R.F., Unmehopa, U.A., Hoogendijk, W.J.G., Heerikhuize, J.J. Van, Hofman, M.A., ...

Alterations in arginine vasopressin neurons in the suprachiasmatic nucleus in depression (2001)

Zhou, J.N., Riemersma, R.F., Unmehopa, U.A., Hoogendijk, W.J.G., Heerikhuize, J.J. Van, Hofman, M.A., ...

Structural and functional sex differences in the human hypothalamus (2001)

Swaab, D.F., Chung, W.C.J., Kruijver, F.P.M., Hofman, M.A., Ishunina, T.A.

Male-to-female transsexuals have female neuron numbers in a limbic nucleus (2000)

Kruijver, F.P.M., Zhou, J.N., Pool, C.W., Hofman, M.A., Gooren, L.J.G., Swaab, D.F.

Decreased vasopressin gene expression in the biological clock of Alzheimer's disease patients with and without depression (2000)

Liu, R.Y., Zhou, J.N., Hoogendijk, W.J.G., Heerikhuize, J. Van, Kamphorst, W., Unmehopa, U.A., ...

Decreased vasopressin gene expression in the biological clock of Alzheimer disease patients with and without depression (2000)

Liu, R-Y., Zhou, J.N., Hoogendijk, W.J.G., Heerikhuize, J.J. Van, Kamphorst, W., Unmehopa, U.A., ...

Male-to-female transsexuals have female neuron numbers in a limbic nucleus (2000)

Kruijver, F.P.M., Zhou, J.N., Pool, C.W., Hofman, M.A., Gooren, L.J.G., Swaab, D.F.

Lack of association between depression and the loss of neurons in the locus coeruleus in Alzheimer's disease (1999)

Hoogendijk, W.J.G., Sommer, I.E.C., Pool, Ch.W., Kamphorst, W., Hofman, M.A., Eikelenboom, P., ...

Activity of vasopressinergic neurons of the human supraoptic nucleus is age and sex dependent (1999)

Ishunina, T.A., Salehi, A., Hofman, M.A., Swaab, D.F.

Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer's disease and ApoE-å 4/4 genotype (1999)

Liu, R., Zhou, J.N., Heerikhuize, J.J., Hofman, M.A., Swaab, D.F.

Lack of association between depression and loss of neurons in the locus coeruleus in Alzheimer disease (1999)

Hoogendijk, W.J.G., Sommer, I.E.C., Pool, C.W., Kamphorst, W., Hofman, M.A., Eikelenboom, P., ...

Activity of vasopressinergic neurones of the human supraoptic nucleus is age- and sex-dependant (1999)

Ishunina, T.A., Salehi, A., Hofman, M.A., Swaab, D.F.

Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer's disease, and apolipoprotein E-epsilon4/4 genotype (1999)

Liu, R-Y., Zhou, J.N., Heerikhuize, J.J. Van, Hofman, M.A., Swaab, D.F.

Depression in Parkinson's disease is not accompanied by more corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus (1998)

Hoogendijk, W.J.G., Purba, J.S., Hofman, M.A., Jansen, E.N.H., Swaab, D.F.

Hersenen in wording (1998)

Uylings, H.B.M., Swaab, D.F., Hofman, M.A.

Depression in Parkinson's disease is not accompanied by more corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus (1998)

Hoogendijk, W.J.G., Purba, J.S., Hofman, M.A., Jansen, E.N.H., Swaab, D.F.

Unchanged amounts of vasopressin mRNA in the supraoptic and paraventricular nucleus during aging and in Alzheimer's disease (1997)

Lucassen, P.J., Heerikhuize, J.J. Van, Guldenaar, S.E.F., Pool, C.W., Hofman, M.A., Swaab, D.F.

Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer's diseases (1997)

Hoogendijk, W.J.G., Mirmiran, M., Hofman, M.A., Lucassen, P.J., Zhou, J.N., ...

Sexual differentiation of the human brain (1997)

Swaab, D.F., Zhou, J.N., Fodor, M., Hofman, M.A.

Sexual differentiation of the human hypothalamus: differences according to sex, sexual orientation, and transsexuality (1997)

Swaab, D.F., Zhou, J.N., Fodor, M., Hofman, M.A.

Sexual differentiation of the human brain (1997)

Swaab, D.F., Zhou, J.N., Fodor, M., Hofman, M.A.

Unchanged amounts of vasopressin mRNA in the supraoptic and paraventricular nucleus during aging and in Alzheimer's disease (1997)

Lucassen, P.J., Heerikhuize, J.J. Van, Guldenaar, S.E.F., Pool, C.W., Hofman, M.A., Swaab, D.F.

Suprachiasmatic nucleus of the human brain: an immunocytochemical and morphometric analysis (1996)

Hofman, M.A., Zhou, J.N., Swaab, D.F.

No evidence for a diurnal vasoactive intestinal polypeptide (VIP) rhythm in the human suprachiasmatic nucleus (1996)

Hofman, M.A., Zhou, J.N., Swaab, D.F.

Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer's disease (1996)

Hoogendijk, W.J.G., Mirmiran, M., Hofman, M.A., Lucassen, P.J., Zhou, J.N., ...

Increased number of vasopressin and oxytocin expressing neurons in the paraventricular nucleus of the human hypothalamus in depression (1996)

Purba, J.S., Hoogendijk, W.J.G., Hofman, M.A., Swaab, D.F.

Morphometric analysis of vasopressin and vasoactive intestinal polypeptide neurons in the human suprachiasmatic nucleus: influence of microwave treatment (1996)

Zhou, J.N., Hofman, M.A., Swaab, D.F.

Biological rhythms in the human life cycle and their relationship to functional changes in the suprachiasmatic nucleus (1996)

Swaab, D.F., Zhou, J.N., Hofman, M.A.

Gender- and sexual orientation-related differences in the human hypothalamus (1996)

Swaab, D.F., Zhou, J.N., Fodor, M., Hofman, M.A.

Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer's diseases (1996)

Hoogendijk, W.J.G., Mirmiran, M., Hofman, M.A., Lucassen, P.J., Zhou, J.N., ...

Increased activity of hypothalamic corticotropin-releasing hormone (CRH) neurons in multiple sclerosis (1995)

Erkut, Z.A., Hofman, M.A., Ravid, R., Swaab, D.F.

Effect of photoperiod on the diurnal melatonin and 5-methoxytryptophol rhythms in the human pineal gland (1995)

Hofman, M.A., Skene, D.J., Swaab, D.F.

Influence of aging on the seasonal rhythm of the human suprachiasmatic nucleus (SCN) (1995)

Hofman, M.A., Swaab, D.F.

Increased light intensity prevents the age related loss of vasopressin-expressing neurons in the rat suprachiasmatic nucleus (1995)

Lucassen, P.J., Hofman, M.A., Swaab, D.F.

Metachronalysis of circannual and circasemiannual characteristics of human suprachiasmatic vasopressin-containing neurons (1995)

Portela, A., Cornélissen, G., Halberg, F., Halberg, Francine, Halberg, J., Hofman, M.A., ...

Increased number of corticotropin releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus of patients with multiple sclerosis (1995)

Purba, J.S., Raadsheer, F.C., Hofman, M.A., Ravid, R., Polman, C.H., Kamphorst, W., ...

Early cytoskeletal changes as shown by Alz-50 are not accompanied by decreased neuronal activity (1995)

Salehi, A., Hofman, M.A., Gonatas, N.K., Swaab, D.F.

Sexual differentiation of the human hypothalamus in relation to gender and sexual orientation (1995)

Swaab, D.F., Hofman, M.A.

Brain Research, Gender and Sexual Orientation (1995)

Swaab, D.F., Gooren, L.J.G., Hofman, M.A.

Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) in Prader-Willi syndrome: A study of five cases (1995)

Swaab, D.F., Purba, J.S., Hofman, M.A.

No vasopressin cell loss in the human paraventricular and supraoptic nucleus during aging and in Alzheimer's disease (1995)

Goudsmit, T., Wierda, M., Purba, J.S., Hofman, M.A., Bogte, H., ...

VIP neurons in the human SCN in relation to sex, age and Alzheimer's disease (1995)

Zhou, J.N., Hofman, M.A., Swaab, D.F.

A sex difference in the human brain and its relation to transsexuality (1995)

Zhou, J.N., Hofman, M.A., Gooren, L.J.G., Swaab, D.F.

No changes in the number of vasoactive intestinal polypeptide (VIP) expressing neurons in the suprachiasmatic nucleus of homosexual men; comparison with vasopressin expressing neurons (1995)

Zhou, J.N., Hofman, M.A., Swaab, D.F.

Alterations in circadian neuronal rhythmicity of the human suprachiasmatic nucleus (SCN) with aging (1994)

Hofman, M.A., Swaab, D.F.

Decreased number of oxytocin-immunoreactive neurons in the paraventricular nucleus of the hypothalamus in Parkinson's disease (1994)

Purba, J.S., Hofman, M.A., Swaab, D.F.

Neuronal atrophy, not cell death, is the main hallmark of Alzheimer's disease (1994)

Swaab, D.F., Hofman, M.A., Lucassen, P.J., Salehi, A., Uylings, H.B.M.

Development of vasoactive intestinal polypeptide (VIP) neurons in the human suprachiasmatic nucleus (SCN) in relation to birth and sex (1994)

Swaab, D.F., Zhou, J.N., Ehlhart, T., Hofman, M.A.

Increased cortisol levels in aging and Alzheimer's disease in postmortem cerebrospinal fluid (1994)

Swaab, D.F., Raadsheer, F.C., Endert, E., Hofman, M.A., Kamphorst, W., Ravid, R.

Age, sex and light: variability in the human suprachiasmatic nucleus (SCN) in relation to its function (1994)

Swaab, D.F., Hofman, M.A.

The human suprachiasmatic nucleus (SCN) in a periodic environment (1994)

Swaab, D.F., Hofman, M.A., Mirmiran, M., Zhou, J.N.

Annual variations in the vasopressin neuron population of the human suprachiasmatic nucleus (1993)

Hofman, M.A., Purba, J.S., Swaab, D.F.

Diurnal and seasonal rhythms of neuronal activity in the suprachiasmatic nucleus of humans (1993)

Hofman, M.A., Swaab, D.F.

Decreased number of oxytocin neurons in the paraventricular nucleus of human hypothalamus in AIDS (1993)

Purba, J.S., Hofman, M.A., Troost, D., Swaab, D.F.

Functional neuroanatomy and neuropathology of the human hypothalamus (1993)

Swaab, D.F., Hofman, M.A., Purba, J.S., Raadsheer, F.C., Lucassen, P.J.

Effects of light and ageing on the human suprachiasmatic nucleus (1993)

Hofman, M.A., Swaab, D.F.

Development and Aging of the biological clock (1993)

Swaab, D.F., Hofman, M.A., Mirmiran, M., Zhou, J.N.

Seasonal changes in the suprachiasmatic nucleus of man (1992)

Hofman, M.A., Swaab, D.F.

The human hypothalamus: comparative morphometry and photoperiodic influences (1992)

Hofman, M.A., Swaab, D.F.

Circadian rhythms and the suprachiasmatic nucleus in perinatal development, aging and Alzheimer's disease (1992)

Mirmiran, M., Swaab, D.F., Kok, J.H., Hofman, M.A., Witting, W., Gool, W.A. Van

The human hypothalamus in relation to gender and sexual orientation (1992)

Swaab, D.F., Gooren, L.J.G., Hofman, M.A.

The human hypothalamus in development, sexual differentiation, aging and Alzheimer's disease (1992)

Swaab, D.F., Goudsmit, E., Kremer, H.P.H., Hofman, M.A., Ravid, R.

Sexual dimorphism of the human brain: myth and reality (1991)

Hofman, M.A., Swaab, D.F.

Oxytocin cell number in the human paraventricular nucleus remains constant with aging and in Alzheimer's disease (1991)

Wierda, M., Goudsmit, E., Purba, J.S., Hofman, M.A., Bogte, H., ...

The supraoptic and paraventricular nuclei of the human hypothalamus in relation to sex, age and Alzheimer's disease (1990)

Goudsmit, E., Hofman, M.A., Fliers, E., Swaab, D.F.

Morphometric analysis of the supraoptic nucleus in the human brain (1990)

Hofman, M.A., Goudsmit, E., Purba, J.S., Swaab, D.F.

An enlarged suprachiasmatic nucleus in homosexual men (1990)

Swaab, D.F., Hofman, M.A.

Development of vasopressin neurons in the human suprachiasmatic nucleus in relation to birth (1990)

Swaab, D.F., Hofman, M.A.

Lifespan changes in vasopressin neurons in the suprachiasmatic nucleus of the human hypothalamus (1990)

Swaab, D.F., Goudsmit, E., Hofman, M.A., Kamphorst, W., Ravid, R., ...

The sexually dimorphic nucleus of the preoptic area in the human brain: a comparative, morphometric study. (1989)

Hofman, M.A., Swaab, D.F.

Morphometric analysis of the suprachiasmatic and paraventricular nuclei in the human brain: sex differences and age-dependent changes (1988)

Hofman, M.A., Fliers, E., Goudsmit, E., Swaab, D.F.

Het op gang komen van de baring: een kwestie van energie? (1988)

Oosterbaan, H.P., Swaab, D.F., Hofman, M.A.

Sexual differentiation of the human hypothalamus: ontogeny of the sexually dimorphic nucleus of the preoptic area (1988)

Swaab, D.F., Hofman, M.A.

Effects of neonatal thermal lesioning of the mesocortical dopaminergic projection on the development of the rat prefrontal cortex (1987)

Kalsbeek, A., Buijs, R.M., Hofman, M.A., Matthijssen, M.A.H., Pool, C.W., Uylings, H.B.M.

Sexuele differentiatie van de menselijke hersenen (1986)

Swaab, D.F., Hofman, M.A., Fliers, E.

Sexuele differentiatie van de menselijke hersenen (1984)

Swaab, D.F., Hofman, M.A.

Sexual differentiation of the human brain. A historical perspective (1984)

Swaab, D.F., Hofman, M.A.

Parturition as an outcome of fetal neuroendocrine stimuli superimposed upon an inherent metabolic mechanism (1984)

Swaab, D.F., Oosterbaan, H.P., Ravid, R., Hofman, M.A.

Sex differences in the hypothalamus in the different stages of human life

Swaab, D.F., Chung, W.C., Kruijver, F.P.M., Hofman, M.A., Hestiantoro, A.

The sexually dimorphic nucleus of the preoptic area in the human brain: a comparative morphometric study.

Hofman, M A, Swaab, D F

The sexually dimorphic nucleus of the preoptic area (SDN-POA) in the human hypothalamus is an ovoid, densely packed collection of large cells. The size, shape and cellular morphology of the SDN-POA...

Morphometric analysis of the supraoptic nucleus in the human brain.

Hofman, M A, Goudsmit, E, Purba, J S, Swaab, D F

The supraoptic nucleus (SON) in the human hypothalamus is an elongated, densely packed collection of large neurosecretory cells. The size, shape and cellular morphology of the dorsolateral part of...

Morphometric analysis of the suprachiasmatic and paraventricular nuclei in the human brain: sex differences and age-dependent changes.

Hofman, M A, Fliers, E, Goudsmit, E, Swaab, D F

The size, shape and cellular morphology of the suprachiasmatic (SCN) and paraventricular nuclei (PVN) in the human hypothalamus were examined in relation to sex and age. In both nuclear regions the...