Mackay, H. J., Hill, M., Twelves, C., Glasspool, R., Price, T., Campbell, S., ...
Background: The aim of this study was to determine the maximum tolerated dose (MTD), toxicity profile and response rate of the oral 5-fluorouracil prodrug UFT (tegafur/uracil) and leucovorin (LV) in...
rhGM-CSF ameliorates neutropenia in patients with malignant glioma treated with BCNU.
Rampling, R., Steward, W., Paul, J., Macham, M. A., Harvey, E., Eckley, D.
Nitrosoureas are the drugs most effective in the treatment of patients with intracerebral malignant glioma. Their limiting toxicity is delayed myelosuppression. A prospective, randomised crossover...