M. A. Richards, R. A. Duncan, V. E. Courtillot, V. E. Courtillot, P. R. Renne, C. R. Geosci, ...
689 (2000). 12. Materials and methods are available as supporting material on Science Online. 13. Age uncertainties are stated at the 2 � level. For sample 96-141 (12) in eastern Zimbabwe, Hanson...
Strong Regularities in World Wide Web Surfing (2007)
B. H. Hager, M. A. Richards, Philos Trans R, Bernardo A. Huberman, James E. Pitkow, ...
26. This CMB response time is accelerated by a factor of 2, relative to a model without core heating. 27. The correspondence of the mantle response time and the time period for reliable...
Subband Adaptive Filtering A Qualifying Examination Report By (2007)
Yaron Seliktar, Dr. M. A. Richards, Dr. D. B. Williams
ii Contents
Impact of hospital consultants' poor mental health on patient care (2007)
Taylor, C., Graham, J., Potts, H.W.W., Candy, J., Richards, M.A., Ramirez, A.J.
In a survey of 1794 UK NHS hospital consultants 1308 (73%) responded. Psychiatric morbidity (General Health Questionnaire–12 score 4) was present in 32% of responders, who were twice as likely to...
Why do older women delay presentation with breast cancer symptoms? (2006)
Burgess, C.C., Potts, H.W.W., Hamed, H., Bish, A.M., Hunter, M.S., Richards, M.A., ...
Women who delay their presentation with breast cancer for three months or longer are more likely to be diagnosed with later stage disease and have poorer survival. Older women, who are at greater...
Advanced breast cancer patients' perceptions of decision making for palliative chemotherapy (2006)
Grunfeld, E.A., Maher, E.J., Browne, S., Ward, P., Young, T., Vivat, B., ...
Purpose: To examine advanced breast cancer patients’ perceptions of the key decision-making consultation for palliative chemotherapy. Patients and Methods: One hundred two women with advanced...
Changes in mental health of UK hospital consultants since the mid-1990s (2005)
Taylor, C., Graham, J., Potts, H.W.W., Richards, M.A., Ramirez, A.J.
We assessed changes in the mental health of UK hospital consultants from five specialties, on the basis of surveys done in 1994 (880 participants) and 2002 (1308 participants). The proportion of...
Does the method of detection of breast cancer affect subsequent psychiatric morbidity? (2002)
Burgess, C.C., Ramirez, A.J., Richards, M.A., Potts, H.W.W.
The aim of this prospective study was to compare the prevalence of psychiatric morbidity following diagnosis of breast cancer between a group of women presenting with screen-detected cancer and a...
Plume generation in natural thermal convection at high Rayleigh and Prandtl numbers (2001)
Lithgow-Bertelloni, C., Richards, M. A., Conrad, C. P., Griffiths, R. W.
We study natural thermal convection of a fluid (corn syrup) with a large Prandtl number (10(3)-10(7)) and temperature-dependent viscosity. The experimental tank (1 x 1 x 0.3 m) is heated from below...
Myeloma during a decade: Clinical experience in a single centre (1995)
Malpas, J. S., Ganjoo, R. K., Johnson, P. W. M., Mahmoud, M. M., Williams, A. H., Carter, M., ...
One hundred and fifty-six patients with multiple myeloma were treated over a period of 12 years at St. Bartholomew's Hospital. The progress of the disease was affected in 96/156 patients...
Twelves, C. J., Richards, M. A., Smith, P., Rubens, R. D.
Fifty-two consecutive patients with breast cancer and liver metastases have been treated with epirubicin. All had a serum aspartate aminotransferase more than twice the upper limit of normal or a...
Richards, M A, Webb, J A, Reznek, R H, Davies, G, Jewell, S E, Shand, W S, ...
The accuracy of spin lattice relaxation time (T1) measurement obtained with a low field strength magnetic resonance imager for the detection of spread of malignant lymphoma to the liver was assessed....
Richards, M A, Webb, J A, Reznek, R H, Davies, G, Jewell, S E, Shand, W S, ...
The accuracy of spin lattice relaxation time (T1) measurement obtained with a low field strength magnetic resonance imager for the detection of spread of malignant lymphoma to the liver was assessed....
Stress and relapse of breast cancer: Authors' reply
Ramirez, Amanda, Craig, T, Watson, J P, Fentiman, Ian S, Richards, M A, North, W R S, ...
Life events and breast cancer prognosis.
Ramirez, A. J., Watson, J. P., Richards, M. A., Fentiman, I. S., Gregory, W. M., Rubens, R. D., ...
Richards, M. A., Parrott, J. C.
OBJECTIVE--To collate information on current activity and facilities in British hospitals to assist the planning of future cancer services. DESIGN--12 hospitals delivering specialist cancer services...
T cell non-Hodgkin's lymphoma presenting in the first trimester of pregnancy.
Lees, C. C., Tsirigotis, M., Carr, J. V., Richards, M. A.
This case report details of the presentation of a young woman in the first trimester of her pregnancy with lethargy, weakness, vomiting, pyrexia and lymphadenopathy. Extensive investigation revealed...
A daily diary for quality of life measurement in advanced breast cancer trials.
Fraser, S. C., Ramirez, A. J., Ebbs, S. R., Fallowfield, L. J., Dobbs, H. J., Richards, M. A., ...
The Qualitator is a daily diary card to measure Quality of Life, developed for use in chemotherapy trials for patients with advanced breast cancer. In a trial at King's College Hospital, 29 patients...
Advanced breast cancer: use of resources and cost implications.
Richards, M. A., Braysher, S., Gregory, W. M., Rubens, R. D.
Little information is currently available on the use of hospital resources and the resulting costs of treating any advanced cancer. Such data may be useful for planning purposes and for calculating...
Ferguson, J. E., Dodwell, D. J., Seymour, A. M., Richards, M. A., Howell, A.
Eighteen patients with advanced breast cancer were commenced on treatment with high dose doxorubicin (100 mg m-2) or doxorubicin (100 mg m-2) and cyclophosphamide (500 mg m-2) at 2 weekly intervals....
Combination chemotherapy for intermediate and high grade non-Hodgkin's lymphoma.
Dhaliwal, H. S., Rohatiner, A. Z., Gregory, W., Richards, M. A., Johnson, P. W., Whelan, J. S., ...
One hundred and eighteen consecutive adults with newly diagnosed intermediate and high-grade non-Hodgkin's lymphoma were treated with chemotherapy comprising Doxorubicin, Cyclophosphamide,...
Spinal cord compression in breast cancer: a review of 70 cases.
Hill, M. E., Richards, M. A., Gregory, W. M., Smith, P., Rubens, R. D.
Spinal cord compression (SCC) is a relatively uncommon but frequently disabling complication of metastatic breast cancer. We have conducted this retrospective study of 70 patients with SCC secondary...
Chemotherapy of advanced breast cancer: outcome and prognostic factors.
Gregory, W. M., Smith, P., Richards, M. A., Twelves, C. J., Knight, R. K., Rubens, R. D.
The outcome for 758 consecutive patients who had received one or more chemotherapy regimens for recurrent or metastatic breast cancer is presented. The response rate following first line treatment...
Twelves, C. J., Dobbs, N. A., Lawrence, M. A., Ramirez, A. J., Summerhayes, M., Richards, M. A., ...
Iododoxorubicin 80 mg m-2 i.v. was given 3 weekly for a maximum of six cycles as first-line chemotherapy to 14 evaluable women with metastatic breast cancer. The response rate was 14% (95% confidence...
Twelves, C. J., Porter, D. A., Lowry, M., Dobbs, N. A., Graves, P. E., Smith, M. A., ...
We have studied the metabolism of 31P-containing metabolites of post-menopausal breast cancers in vivo using magnetic resonance spectroscopy (MRS) and a 5.5 cm surface coil. Spectra were acquired...
DNA index, S-phase fraction, histological grade and prognosis in breast cancer.
O'Reilly, S. M., Camplejohn, R. S., Barnes, D. M., Millis, R. R., Allen, D., Rubens, R. D., ...
DNA index and S-phase fraction (SPF) were measured by flow cytometry on paraffin embedded tissue from 140 primary breast tumours. The results of DNA analysis were compared with the size, degree of...
The relationship between c-erbB-2 expression, S-phase fraction and prognosis in breast cancer.
O'Reilly, S. M., Barnes, D. M., Camplejohn, R. S., Bartkova, J., Gregory, W. M., Richards, M. A.
The relationship between c-erbB-2 gene expression (assessed immunohistochemically), S-phase fraction (SPF) and prognosis has been analysed in 172 women with primary breast cancer. c-erbB-2 staining...
Clinical pharmacokinetics of epirubicin: the importance of liver biochemistry tests.
Twelves, C. J., Dobbs, N. A., Michael, Y., Summers, L. A., Gregory, W., Harper, P. G., ...
The influence of liver biochemistry tests on epirubicin pharmacokinetics has been investigated in 52 women with advanced breast cancer, 27 of whom had radiologically proven liver metastases. Patients...
Chlorambucil and interferon for low grade non-Hodgkin's lymphoma.
Rohatiner, A. Z., Richards, M. A., Barnett, M. J., Stansfeld, A. G., Lister, T. A.
Camplejohn, R. S., Ash, C. M., Gillett, C. E., Raikundalia, B., Barnes, D. M., Gregory, W. M., ...
In this single-centre study of 881 patients, S-phase fraction (SPF) was shown to be a significant prognostic marker in terms of overall survival (OS), relapse-free survival (RFS) and survival after...
Rasbridge, S. A., Gillett, C. E., Seymour, A. M., Patel, K., Richards, M. A., Rubens, R. D., ...
The use of chemotherapy as a form of primary treatment for breast cancer is increasing and, as a result, more resection specimens contain tumours which have been exposed to cytotoxic drugs. We have...
Burnout and psychiatric disorder among cancer clinicians.
Ramirez, A. J., Graham, J., Richards, M. A., Cull, A., Gregory, W. M., Leaning, M. S., ...
The prevalence and causes of 'burnout' and psychiatric disorder among senior oncologists and palliative care specialists have been measured in a national questionnaire-based survey. All consultant...
Can mood disorder in women with breast cancer be identified preoperatively?
Ramirez, A. J., Richards, M. A., Jarrett, S. R., Fentiman, I. S.
The Hospital Anxiety and Depression (HAD) scale, a self-report questionnaire, was tested as a method of identifying mood disorder among patients with operable breast cancer during the year after...
Do patients with advanced breast cancer benefit from chemotherapy?
Ramirez, A. J., Towlson, K. E., Leaning, M. S., Richards, M. A., Rubens, R. D.
This study aimed to assess the proportion of patients with advanced breast cancer who report benefit from first-line palliative chemotherapy using a simple global measure of wellbeing and to identify...
Richards, M. A., Wolfe, C. D., Tilling, K., Barton, J., Bourne, H. M., Gregory, W. M.
A retrospective, population-based study was undertaken to determine variations in the management of women aged less than 50 years with primary breast cancer in different hospital settings and the...
Serum progesterone and prognosis in operable breast cancer.
Mohr, P. E., Wang, D. Y., Gregory, W. M., Richards, M. A., Fentiman, I. S.
Several studies have now shown that women with operable breast cancer undergoing tumour excision during the luteal phase of the menstrual cycle have a better prognosis than those having surgery...
Who and what influences delayed presentation in breast cancer?
Burgess, C. C., Ramirez, A. J., Richards, M. A., Love, S. B.
This study aimed to examine the extent and determinants of patient and general practitioner delay in the presentation of breast cancer. One hundred and eighty-five cancer patients attending a breast...
Low field strength magnetic resonance imaging of bone marrow in patients with malignant lymphoma.
Richards, M. A., Webb, J. A., Jewell, S. E., Amess, J. A., Wrigley, P. F., Lister, T. A.
Detection of bone marrow infiltration by lymphoma with low field strength magnetic resonance imaging (MRI) has been assessed. Measurements of spin lattice relaxation time (T1) were made in 31...
Richards, M. A., Webb, J. A., Jewell, S. E., Stansfeld, A. G., Lister, T. A., Wrigley, P. F.
Low field strength (0.08 Tesla) magnetic resonance imaging (MRI) of the spleen with spin lattice relaxation time (T1) measurement was performed on a total of 79 healthy volunteers and 62 patients...
Weekly epirubicin for breast cancer with liver metastases and abnormal liver biochemistry.
Twelves, C. J., O'Reilly, S. M., Coleman, R. E., Richards, M. A., Rubens, R. D.
Thirty-six consecutive patients with breast cancer and liver metastases with abnormal liver biochemistry were treated with epirubicin 25 mg m-2 i.v. weekly. No dose modification was made for abnormal...
The influence on survival of delay in the presentation and treatment of symptomatic breast cancer
Richards, M A, Smith, P, Ramirez, A J, Fentiman, I S, Rubens, R D
The aim of this study was to examine the possible influence on survival of delays prior to presentation and/or treatment among women with breast cancer. Duration of symptoms prior to hospital...
Chemotherapy for advanced breast cancer: what influences oncologists' decision-making?
Grunfeld, E A, Ramirez, A J, Maher, E J, Peach, D, Young, T, Albery, I P, ...
Chemotherapy is widely used in the management of patients with advanced breast cancer. However, a considerable proportion of patients experience toxic side effects without gaining benefit. This study...
Women's knowledge and beliefs regarding breast cancer
Grunfeld, E A, Ramirez, A J, Hunter, M S, Richards, M A
Approximately 20–30% of women delay for 12 weeks or more from self-discovery of a breast symptom to presentation to a health care provider, and such delay intervals are associated with poorer...