Cantaert, T., Stone, M. A., Ter Borg, M., Mogg, R., De Vries, N., Wilson, A. G., ...
Objective: A genetic variant of the toll-like receptor (TLR) 2/4 adaptor protein TIRAP (single nucleotide polymorphism (SNP) C539T) was identified in a UK and in several African populations. The...
Stone, M. A., Pomeroy, E., Keat, A., Sengupta, R., Hickey, S., Dieppe, P., ...
Objectives. Many AS patients report periods of perceived higher disease activity (flares). This pilot study aims to document disease activity patterns reported by AS patients and examine associations...
Khunti, K., Stone, M. A., Bankart, J., Sinfield, P., Pancholi, A., Walker, S., ...
Background Escalating rates of childhood obesity are likely to have an impact on the prevalence of coronary heart disease and type-2 diabetes. We aimed to identify barriers to healthy lifestyles and...
The assessment of ankylosing spondylitis in clinical practice (2007)
Ankylosing Spondylitis (AS) is a chronic inflammatory arthritis that predominantly affects the axial skeleton in adolescent patients causing spinal pain and stiffness. There is a marked delay, on...
Gladman, D. D., Inman, R. D., Cook, R. J., Landewe, R. B. M., Braun, J., ...
Objective. To determine whether the axial measures used in primary ankylosing spondylitis (AS) were reproducible for both AS and psoriatic arthritis (PsA) with axial disease. Methods. A group of 20...
Gladman, D. D., Inman, R. D., Cook, R. J., Maksymowych, W. P., Braun, J., Davis, J. C., ...
Objective. To determine whether the assessments of peripheral joints and enthesitis were reproducible for both AS and PsA with axial disease, and whether dactylitis assessment is reproducible in...
Bcl-x(L) expression in vivo in rheumatoid synovium (2006)
Busteed, S., Bennett, M. W., Molloy, C., Houston, A., Stone, M. A., Shanahan, F., ...
To examine the expression of the apoptosis regulatory protein, Bcl-x(L), in the synovium of patients with rheumatoid arthritis (RA) and osteoarthritis (OA). Immunohistochemistry for Bcl-x(L) was...
Reliability of physical examination in inflammatory arthritis: Rope study (2005)
Stone, M. A., White, L., Gladman, D., Inman, R. D., Chhaya, S., Lax, M., ...
Validation of a self assessment spinal deformity tool for ankylosing spondylitis (2005)
Podbielski, D., Bruckel, J., Warren, R. W., Inman, R. D., Cortinovis, D., Papachristos, A., ...
Kim, T. H., Stone, M. A., Rahman, P., Yoo, D. H., Park, Y. W., Payne, U., ...
Objective. The interleukin 1 alpha and 1 beta (IL-1 alpha, IL-1 beta) are potent mediators of inflammation and immunity. IL-1 receptor antagonist (IL-1Ra) is a protein that binds to IL-1 receptors...
Stone, M. A., Payne, U., Schentag, C., Rahman, P., Pacheco-Tena, C., Inman, R. D.
Objective. Using humoral immune responses, Klebsiella pneumoniae has been implicated as a candidate microbial trigger in ankylosing spondylitis (AS) by several investigators but refuted by others....
Stone, M. A., Payne, U., Pacheco-Tena, C., Inman, R. D.
Objective: To identify clinical and immunological markers of response to treatment with infliximab in ankylosing spondylitis (AS). Methods: Baseline and sequential cytokine levels (IL1, TNFalpha,...
Stone, M. A., Inman, R. D., Wright, J. G., Maetzel, A.
Objectives. To define what expert clinicians consider a dramatic response in ankylosing spondylitis (AS) patients treated with biologic therapies based on patient and physician assessments of global...
Recent advances in the treatment of the spondyloarthropathies (2004)
Liu, Y., Cortinovis, D., Stone, M. A.
Purpose of review Recently, there has been renewed interest in the spondyloarthropathy family of chronic inflammatory rheumatic conditions, which has been fueled to a large extent by the biologic...
Lack of linkage of IL1RN genotypes with ankylosing spondylitis susceptibility (2004)
Jin, L., Zhang, G., Akey, J. M., Luo, J. C., Lee, J., Weisman, M. H., ...
Gladman, D. D., Cook, R. J., Schentag, C., Feletar, M., Inman, R. I., Hitchon, C., ...
Objectives. To evaluate whether rheumatologists experienced in psoriatic arthritis (PsA) assess peripheral and axial involvement in the same way and to consider core clinical measurements that should...
Stone, M. A., Payne, U., Schentag, C., Rahman, P., Pacheco-Tena, C., Inman, R. D.
Objective. Using humoral immune responses, Klebsiella pneumoniae has been implicated as a candidate microbial trigger in ankylosing spondylitis (AS) by several investigators but refuted by others....
Stone, M. A., Payne, U., Schentag, C., Rahman, P., Pacheco-Tena, C., Inman, R. D.
Objective. Using humoral immune responses, Klebsiella pneumoniae has been implicated as a candidate microbial trigger in ankylosing spondylitis (AS) by several investigators but refuted by others....
Stone, M. A., Payne, U., Schentag, C., Rahman, P., Pacheco-Tena, C., Inman, R. D.
Objective. Using humoral immune responses, Klebsiella pneumoniae has been implicated as a candidate microbial trigger in ankylosing spondylitis (AS) by several investigators but refuted by others....
The effects of lithium and cholinergic stimulation on inositol phospholipid metabolism have been assessed using rat parotid gland slices and isolated acinar cells labelled with 32Pi. Cholinergic...
The effects of lithium and cholinergic stimulation on inositol phospholipid metabolism have been assessed using rat parotid gland slices and isolated acinar cells labelled with 32Pi. Cholinergic...
Downes, C. P., Lewis, P. E., Stone, M. A.
The present study investigates the relationship between binding at the sigma site labelled by the prototypic sigma ligand (+)-[3H]-N-allylnormetazocine [+)-[3H]-SKF10,047) and binding at the...