M. ALAM

Publication List Details

Period

1977 - 9999

Number

86

Co-Authors

Oxidation of CVD Diamond Films. (9999)

Sun, Q., Alam, M.

Thermal oxidation of CVD diamond films on 111 oriented silicon wafers in oxygen at atmospheric pressure and up to 1273 K was investigated by thermogravimetry. The data is compared with that of 100...

A rat model of Parkinsonism shows depletion of dopamine in the retina. (2007)

Biehlmaier, O, Alam, M, Schmidt, W J

The retinal dopamine (DA) deficiency is an important feature of the pathogenesis in Parkinson's disease (PD) visual dysfunction. Systemic inhibition of complex I (rotenone) in rats has been proposed...

Rheology of granular mixtures under uniform shear flow: Enskog kinetic theory versus molecular dynamics simulations (2004)

Montanero, J. M., Garzo, V., Alam, M., Luding, S.

The rheological properties for dilute and moderately dense granular binary mixtures of smooth, inelastic hard disks/spheres under uniform shear flow in steady state conditions are reported. The...

Triacylglycerol hydrolase: role in intracellular lipid metabolism (2004)

Dolinsky, V. W., Gilham, D., Alam, M., Vance, D. E., Lehner, R.

Recent scientific advances have revealed the identity of several enzymes involved in the synthesis, storage and catabolism of intracellular neutral lipid storage droplets. An enzyme that hydrolyzes...

Segregation in a fluidized binary granular mixture: Competition between buoyancy and geometric forces (2003)

Trujillo, L., Alam, M., Herrmann, H. J.

Starting from the hydrodynamic equations of binary granular mixtures, we derive an evolution equation for the relative velocity of the intruders, which is shown to be coupled to the inertia of the...

Two-equation turbulence modelling of a transitional separation bubble (2000)

Howard, R.J.A., Alam, M., Sandham, N.D.

Calculations of the Reynolds averaged equations using twodifferent turbulence models have been compared with direct numericalsimulation of a transitional separation bubble. Three methods oftransition...

Direct numerical simulation of 'short' laminar separation bubbles with turbulent reattachment (2000)

Alam, M., Sandham, N.D.

Direct numerical simulation of the incompressible Navier–Stokes equations is used to study flows where laminar boundary-layer separation is followed by turbulent reattachment forming a closed...

Adhesion Between CVD Diamond Films and Tungsten. (1998)

Alam, M., Peebles, D. E., Tallant, D. R.

Adhesion between diamond films synthesized by a CVD method and tungsten has been investigated by pull testing method. Diamond films have been deposited at temperatures from 1173 to 1323 K with a...

Oxidation of CVD Diamond Films. (1998)

Sun, Q., Alam, M.

Thermal oxidation of CVD diamond films on 111 oriented silicon wafers in oxygen at atmospheric pressure and up to 1273 K was investigated by thermogravimetry. The data is compared with that of 100...

Thermal Oxidation Characteristics of Chemical Vapour Deposited Diamond Films. (1998)

Sun, Q., Alam, M.

Thermal oxidation characteristics of chemical vapor deposited diamond films were studied at 973 K and at different oxygen potentials by analyzing the samples before and after partial oxidation using...

Effect of Sulphur on Health of Fayoumi Chicken (1998)

M. Alam, A. D. Anjum, M. Z. Akhtar

Fayoumi birds were supplemented with 0 (control), 1, 2, 3 and 4 per cent elementary sulphur in feed from 56 days to 140 days of age. Clinically, faeces in birds fed by 2, 3 and 4 per cent sulphur...

Transient surface grating technique for thermal diffusivity measurement (1994)

Alam, M., Imhof, R., Zhang, B.

A new transient surface grating technique specifically designed for measuring thermal diffusivities of condensed materials is described. Its capabilities are illustrated with measurements of the...

Transient surface grating technique for thermal diffusivity measurement (1994)

Alam, M., Imhof, R., Zhang, B.

A new transient surface grating technique specifically designed for measuring thermal diffusivities of condensed materials is described. Its capabilities are illustrated with measurements of the...

Transient surface grating technique for thermal diffusivity measurement (1994)

Alam, M., Imhof, R., Zhang, B.

A new transient surface grating technique specifically designed for measuring thermal diffusivities of condensed materials is described. Its capabilities are illustrated with measurements of the...

Enteric fever in patients admitted to a diarrhoeal disease hospital in Bangladesh. (1983)

Stoll, Barbara J., Banu, H., Alam, M.

The hospital records of 62 patients with blood culture-proven enteric fever admitted to the Dacca Hospital of the International Centre for Diarrhoeal Disease Research, Bangladesh, over a one-year...

MULTILAYER SINTERING OF MnZn FERRITES IN CONTROLLED ATMOSPHERE (1977)

Alam, M., Nair, N., Ramamurti, T.

It has been reported in literature that stacking of cup cores one over the other causes significant variations in electrical characteristics due to a shadow effect. At National Physical Laboratory a...

MULTILAYER SINTERING OF MnZn FERRITES IN CONTROLLED ATMOSPHERE (1977)

Alam, M., Nair, N., Ramamurti, T.

It has been reported in literature that stacking of cup cores one over the other causes significant variations in electrical characteristics due to a shadow effect. At National Physical Laboratory a...

MULTILAYER SINTERING OF MnZn FERRITES IN CONTROLLED ATMOSPHERE (1977)

Alam, M., Nair, N., Ramamurti, T.

It has been reported in literature that stacking of cup cores one over the other causes significant variations in electrical characteristics due to a shadow effect. At National Physical Laboratory a...

The primary structures of the Archaeon Halobacterium salinarium blue light receptor sensory rhodopsin II and its transducer, a methyl-accepting protein.

Zhang, W, Brooun, A, Mueller, M M, Alam, M

Recently, a large family of transducer proteins in the Archaeon Halobacterium salinarium was identified. On the basis of the comparison of the predicted structural domains of these transducers, three...

Signal transduction in the archaeon Halobacterium salinarium is processed through three subfamilies of 13 soluble and membrane-bound transducer proteins.

Zhang, W, Brooun, A, McCandless, J, Banda, P, Alam, M

Eubacterial transducers are transmembrane, methyl-accepting proteins central to chemotaxis systems and share common structural features. We identified a large family of transducer proteins in the...

Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitors.

Rose, R E, Gong, Y F, Greytok, J A, Bechtold, C M, Terry, B J, Robinson, B S, ...

The observed in vitro and in vivo benefit of combination treatment with anti-human immunodeficiency virus (HIV) agents prompted us to examine the potential of resistance development when two protease...

Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease.

Bechtold, C M, Patick, A K, Alam, M, Greytok, J, Tino, J A, Chen, P, ...

A series of aminodiol inhibitors of human immunodeficiency virus type 1 (HIV-1) protease were identified by using an in vitro peptide cleavage assay. BMS 182,193, BMS 186,318, and BMS 187,071...

Characterization of siamycin I, a human immunodeficiency virus fusion inhibitor.

Lin, P F, Samanta, H, Bechtold, C M, Deminie, C A, Patick, A K, Alam, M, ...

The human immunodeficiency virus (HIV) fusion inhibitor siamycin I, a 21-residue tricyclic peptide, was identified from a Streptomyces culture by using a cell fusion assay involving cocultivation of...

Evaluation of reverse transcriptase and protease inhibitors in two-drug combinations against human immunodeficiency virus replication.

Deminie, C A, Bechtold, C M, Stock, D, Alam, M, Djang, F, Balch, A H, ...

Current treatments for human immunodeficiency virus (HIV) include both reverse transcriptase and protease inhibitors. Results from in vitro and clinical studies suggest that combination therapy can...

Lobucavir is phosphorylated in human cytomegalovirus-infected and -uninfected cells and inhibits the viral DNA polymerase.

Tenney, D J, Yamanaka, G, Voss, S M, Cianci, C W, Tuomari, A V, Sheaffer, A K, ...

Lobucavir (LBV) is a deoxyguanine nucleoside analog with broad-spectrum antiviral activity. LBV was previously shown to inhibit herpes simplex virus (HSV) DNA polymerase after phosphorylation by the...

Expression of virulence-related properties by, and intestinal adhesiveness of, Vibrio mimicus strains isolated from aquatic environments.

Alam, M, Miyoshi, S, Yamamoto, S, Tomochika, K, Shinoda, S

A study of the major pathogenic characteristics of Vibrio mimicus was carried out with 77 strains isolated from aquatic environments in Okayama, Japan. Of the strains tested, 96% demonstrated in...

Hemagglutination is a novel biological function of lipopolysaccharide (LPS), as seen with the Vibrio cholerae O139 LPS.

Alam, M, Miyoshi, S, Tomochika, K, Shinoda, S

It has been generally thought that the polysaccharide moiety of lipopolysaccharide (LPS) maintains only serological specificity, while the lipid A portion determines various biological functions....

Purification and characterization of novel hemagglutinins from Vibrio mimicus: a 39-kilodalton major outer membrane protein and lipopolysaccharide.

Alam, M, Miyoshi, S I, Tomochika, K I, Shinoda, S

Two hemagglutinins (HAs) mediating the agglutinability to rabbit erythrocytes were isolated from 32-h culture supernatant of enterotoxigenic strain E-33 of Vibrio mimicus by ultrafiltration followed...

Vibrio mimicus attaches to the intestinal mucosa by outer membrane hemagglutinins specific to polypeptide moieties of glycoproteins.

Alam, M, Miyoshi, S, Tomochika, K, Shinoda, S

Vibrio mimicus is the closest organism to Vibrio cholerae. V. mimicus E-33, which is a highly adhesive and enteropathogenic strain, is known to produce three types of hemagglutinins (HAs), i.e., a...

Primary structure and functional analysis of the soluble transducer protein HtrXI in the archaeon Halobacterium salinarium.

Brooun, A, Zhang, W, Alam, M

Signal transduction in the archaeon Halobacterium salinarium is mediated by a family of 13 soluble and membrane-bound transducers. Here, we report the primary structure and functional analysis of one...

Rotation and switching of the flagellar motor assembly in Halobacterium halobium.

Marwan, W, Alam, M, Oesterhelt, D

Halobacterium halobium swims with a polarly inserted motor-driven flagellar bundle. The swimming direction of the cell can be reserved by switching the rotational sense of the bundle. The switch is...

Structural features of methyl-accepting taxis proteins conserved between archaebacteria and eubacteria revealed by antigenic cross-reaction.

Alam, M, Hazelbauer, G L

A number of eubacterial species contain methyl-accepting taxis proteins that are antigenically and thus structurally related to the well-characterized methyl-accepting chemotaxis proteins of...

Characterization of Halobacterium halobium mutants defective in taxis.

Sundberg, S A, Alam, M, Lebert, M, Spudich, J L, Oesterhelt, D, Hazelbauer, G L

Mutant derivatives of Halobacterium halobium previously isolated by using a procedure that selected for defective phototactic response to white light were examined for an array of phenotypic...

Occurrence of resistance to vibriostatic compound 0/129 in Vibrio cholerae 01 isolated from clinical and environmental samples in Bangladesh.

Huq, A, Alam, M, Parveen, S, Colwell, R R

Fifty-one Vibrio cholerae 01 strains isolated from 734 natural water and plankton samples and 31 rectal swabs were examined. Of these strains, 32 (62.7%) were found to be resistant to vibriostatic...

Methyl-accepting taxis proteins in Halobacterium halobium.

Alam, M, Lebert, M, Oesterhelt, D, Hazelbauer, G L

Methyl-accepting taxis proteins were identified and characterized in Halobacterium halobium, an archaebacterial species that is both chemotactic and phototactic. The data suggest direct involvement...

Flagella and motility behaviour of square bacteria.

Alam, M, Claviez, M, Oesterhelt, D, Kessel, M

Square bacteria are shown to have right-handed helical (RH) flagella. They swim forward by clockwise (CW), and backwards by counterclockwise (CCW) rotation of their flagella. They are propelled by...

Differential effects of sulfhydryl reagents on saxitoxin and tetrodotoxin block of voltage-dependent Na channels.

Kirsch, G E, Alam, M, Hartmann, H A

We have probed a cysteine residue that confers resistance to tetrodotoxin (TTX) block in heart Na channels, with membrane-impermeant, cysteine-specific, methanethiosulfonate (MTS) analogs. Covalent...

Excitation signal processing times in Halobacterium halobium phototaxis.

Sundberg, S A, Alam, M, Spudich, J L

Phototaxis responses of Halobacterium halobium were monitored with a computerized cell-tracking system coupled to an electronic shutter controlling delivery of photostimuli. Automated analysis of...

The primary structures of the Archaeon Halobacterium salinarium blue light receptor sensory rhodopsin II and its transducer, a methyl-accepting protein.

Zhang, W, Brooun, A, Mueller, M M, Alam, M

Recently, a large family of transducer proteins in the Archaeon Halobacterium salinarium was identified. On the basis of the comparison of the predicted structural domains of these transducers, three...

Signal transduction in the archaeon Halobacterium salinarium is processed through three subfamilies of 13 soluble and membrane-bound transducer proteins.

Zhang, W, Brooun, A, McCandless, J, Banda, P, Alam, M

Eubacterial transducers are transmembrane, methyl-accepting proteins central to chemotaxis systems and share common structural features. We identified a large family of transducer proteins in the...

Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitors.

Rose, R E, Gong, Y F, Greytok, J A, Bechtold, C M, Terry, B J, Robinson, B S, ...

The observed in vitro and in vivo benefit of combination treatment with anti-human immunodeficiency virus (HIV) agents prompted us to examine the potential of resistance development when two protease...

Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease.

Bechtold, C M, Patick, A K, Alam, M, Greytok, J, Tino, J A, Chen, P, ...

A series of aminodiol inhibitors of human immunodeficiency virus type 1 (HIV-1) protease were identified by using an in vitro peptide cleavage assay. BMS 182,193, BMS 186,318, and BMS 187,071...

Characterization of siamycin I, a human immunodeficiency virus fusion inhibitor.

Lin, P F, Samanta, H, Bechtold, C M, Deminie, C A, Patick, A K, Alam, M, ...

The human immunodeficiency virus (HIV) fusion inhibitor siamycin I, a 21-residue tricyclic peptide, was identified from a Streptomyces culture by using a cell fusion assay involving cocultivation of...

Evaluation of reverse transcriptase and protease inhibitors in two-drug combinations against human immunodeficiency virus replication.

Deminie, C A, Bechtold, C M, Stock, D, Alam, M, Djang, F, Balch, A H, ...

Current treatments for human immunodeficiency virus (HIV) include both reverse transcriptase and protease inhibitors. Results from in vitro and clinical studies suggest that combination therapy can...

Lobucavir is phosphorylated in human cytomegalovirus-infected and -uninfected cells and inhibits the viral DNA polymerase.

Tenney, D J, Yamanaka, G, Voss, S M, Cianci, C W, Tuomari, A V, Sheaffer, A K, ...

Lobucavir (LBV) is a deoxyguanine nucleoside analog with broad-spectrum antiviral activity. LBV was previously shown to inhibit herpes simplex virus (HSV) DNA polymerase after phosphorylation by the...

Expression of virulence-related properties by, and intestinal adhesiveness of, Vibrio mimicus strains isolated from aquatic environments.

Alam, M, Miyoshi, S, Yamamoto, S, Tomochika, K, Shinoda, S

A study of the major pathogenic characteristics of Vibrio mimicus was carried out with 77 strains isolated from aquatic environments in Okayama, Japan. Of the strains tested, 96% demonstrated in...

Hemagglutination is a novel biological function of lipopolysaccharide (LPS), as seen with the Vibrio cholerae O139 LPS.

Alam, M, Miyoshi, S, Tomochika, K, Shinoda, S

It has been generally thought that the polysaccharide moiety of lipopolysaccharide (LPS) maintains only serological specificity, while the lipid A portion determines various biological functions....

Purification and characterization of novel hemagglutinins from Vibrio mimicus: a 39-kilodalton major outer membrane protein and lipopolysaccharide.

Alam, M, Miyoshi, S I, Tomochika, K I, Shinoda, S

Two hemagglutinins (HAs) mediating the agglutinability to rabbit erythrocytes were isolated from 32-h culture supernatant of enterotoxigenic strain E-33 of Vibrio mimicus by ultrafiltration followed...

Vibrio mimicus attaches to the intestinal mucosa by outer membrane hemagglutinins specific to polypeptide moieties of glycoproteins.

Alam, M, Miyoshi, S, Tomochika, K, Shinoda, S

Vibrio mimicus is the closest organism to Vibrio cholerae. V. mimicus E-33, which is a highly adhesive and enteropathogenic strain, is known to produce three types of hemagglutinins (HAs), i.e., a...

Primary structure and functional analysis of the soluble transducer protein HtrXI in the archaeon Halobacterium salinarium.

Brooun, A, Zhang, W, Alam, M

Signal transduction in the archaeon Halobacterium salinarium is mediated by a family of 13 soluble and membrane-bound transducers. Here, we report the primary structure and functional analysis of one...

Rotation and switching of the flagellar motor assembly in Halobacterium halobium.

Marwan, W, Alam, M, Oesterhelt, D

Halobacterium halobium swims with a polarly inserted motor-driven flagellar bundle. The swimming direction of the cell can be reserved by switching the rotational sense of the bundle. The switch is...

Structural features of methyl-accepting taxis proteins conserved between archaebacteria and eubacteria revealed by antigenic cross-reaction.

Alam, M, Hazelbauer, G L

A number of eubacterial species contain methyl-accepting taxis proteins that are antigenically and thus structurally related to the well-characterized methyl-accepting chemotaxis proteins of...

Characterization of Halobacterium halobium mutants defective in taxis.

Sundberg, S A, Alam, M, Lebert, M, Spudich, J L, Oesterhelt, D, Hazelbauer, G L

Mutant derivatives of Halobacterium halobium previously isolated by using a procedure that selected for defective phototactic response to white light were examined for an array of phenotypic...

Occurrence of resistance to vibriostatic compound 0/129 in Vibrio cholerae 01 isolated from clinical and environmental samples in Bangladesh.

Huq, A, Alam, M, Parveen, S, Colwell, R R

Fifty-one Vibrio cholerae 01 strains isolated from 734 natural water and plankton samples and 31 rectal swabs were examined. Of these strains, 32 (62.7%) were found to be resistant to vibriostatic...

Methyl-accepting taxis proteins in Halobacterium halobium.

Alam, M, Lebert, M, Oesterhelt, D, Hazelbauer, G L

Methyl-accepting taxis proteins were identified and characterized in Halobacterium halobium, an archaebacterial species that is both chemotactic and phototactic. The data suggest direct involvement...

Flagella and motility behaviour of square bacteria.

Alam, M, Claviez, M, Oesterhelt, D, Kessel, M

Square bacteria are shown to have right-handed helical (RH) flagella. They swim forward by clockwise (CW), and backwards by counterclockwise (CCW) rotation of their flagella. They are propelled by...