Serum bile acids in patients with hyperlipidaemia.
Pennington, C R, Ross, P E, Bateson, M C, Bouchier, I A
Individual serum bile acids were analysed by an improved gas liquid chromatography method in 12 patients with primary hyperlipidaemia. Total serum bile acid concentrations were raised in 10 subjects....
A comparative trial of liver biopsy needles.
Bateson, M C, Hopwood, D, Duguid, H L, Bouchier, I A
A sheathed needle (Tru-Cut) was compared with a suction biopsy needle (Menghini) in a randomised prospective trial over 18 months to determine whether the former offered any special advantages in...
Calcification of radiolucent gall stone during treatment with ursodeoxycholic acid.
Bateson, M C, Bouchier, I A, Trash, D B, Maudgal, D P, Northfield, T C
Reversal of clofibrate-induced cholesterol oversaturation of bile with chenodeoxycholic acid.
Bateson, M C, Ross, P E, Murison, J, Bouchier, I A
Giving clofibrate 2 g daily to seven patients significantly increased the biliary cholesterol concentration while the proportion of bile acids fell. Five patients on established clofibrate treatment...
Sleep Epilepsy: Its Pattern and Prognosis
Gibberd, F. B., Bateson, M. C.
In a series of 645 patients with epilepsy only 38 had attacks exclusively during sleep. A further 111 had attacks while waking and sleeping. The total number of patients whose epilepsy started with...
Serum bile acids in patients with hyperlipidaemia.
Pennington, C R, Ross, P E, Bateson, M C, Bouchier, I A
Individual serum bile acids were analysed by an improved gas liquid chromatography method in 12 patients with primary hyperlipidaemia. Total serum bile acid concentrations were raised in 10 subjects....
A comparative trial of liver biopsy needles.
Bateson, M C, Hopwood, D, Duguid, H L, Bouchier, I A
A sheathed needle (Tru-Cut) was compared with a suction biopsy needle (Menghini) in a randomised prospective trial over 18 months to determine whether the former offered any special advantages in...
Calcification of radiolucent gall stone during treatment with ursodeoxycholic acid.
Bateson, M C, Bouchier, I A, Trash, D B, Maudgal, D P, Northfield, T C
Reversal of clofibrate-induced cholesterol oversaturation of bile with chenodeoxycholic acid.
Bateson, M C, Ross, P E, Murison, J, Bouchier, I A
Giving clofibrate 2 g daily to seven patients significantly increased the biliary cholesterol concentration while the proportion of bile acids fell. Five patients on established clofibrate treatment...
Sleep Epilepsy: Its Pattern and Prognosis
Gibberd, F. B., Bateson, M. C.
In a series of 645 patients with epilepsy only 38 had attacks exclusively during sleep. A further 111 had attacks while waking and sleeping. The total number of patients whose epilepsy started with...
Bateson, M C, Ross, P E, Murison, J, Bouchier, I A
Nineteen patients who received chenodeoxycholic acid 750 mg/day for six months had duodenal bile aspirated before and after treatment. In five patients with hypertriglyceridaemia but no gallstones...
Effects of bile acids and hydrogen ion on the fine structure of oesophageal epithelium.
Hopwood, D, Bateson, M C, Milne, G, Bouchier, I A
Oesophageal mucosal biopsies were incubated in 20, 0, and 0.2mM solutions of cholic, chenodeoxycholic, ursodeoxycholic, and deoxycholic bile acids. Both conjugated and unconjugated bile acids were...
Ursodeoxycholic acid therapy and biliary lipids--a dose-response study.
Bateson, M C, Ross, P E, Murison, J, Saunders, J H, Bouchier, I A
The effects of four different doses of ursodeoxycholic acid (250, 500, 750, and 1000 mg daily) on biliary lipids were studied in 24 patients with radiolucent gallbladder stones. There was a...
Bate, C M, Wilkinson, S P, Bradby, G V, Bateson, M C, Hislop, W S, Crowe, J P, ...
In a randomised, double blind, parallel group study in patients with symptomatic gastric ulcer (94% greater than or equal to 5 mm diameter), 102 received omeprazole 20 mg om and 87 cimetidine 400 mg...
Chenodeoxycholic acid therapy for hypertriglyceridaemia in men.
Bateson, M C, Maclean, D, Evans, J R, Bouchier, I A
1 Ten consecutive patients with hypertriglyceridaemia who adhered to a low carbohydrate diet without complete control of serum triglycerides were started on chenodeoxycholic acid 750 mg daily and...
The effect of ursodeoxycholic acid treatment on survival in primary biliary cirrhosis was studied in 40 patients with symptomatic disease. Two patients developed early exacerbation of symptoms and...
Cigarette smoking and Helicobacter pylori infection.
The direct urease test was used in 462 patients with normal upper digestive tracts, 108 with duodenal ulcers and 43 with gastric ulcers who attended for upper digestive endoscopy in a prospective...
The association of oesophagitis with disease in the stomach and duodenum.
Bateson, M. C., Bouchier, I. A.
The records of all upper digestive endoscopies performed in one year in the Clinical Measurement Department of a teaching hospital serving a population of 250 000 were reviewed; 25% of patients had...
A case is described of severe recurrent ischaemic heart disease associated with rapidly increasing and ultimately massive hyperlipidaemia. The case is discussed, with suggestions for management of...
Bateson, M. C., Beck, J. S., Clark, J., Baxby, K., Bouchier, Ian A. D.
The occurrence of several unusual disorders in a single patient prompted the question as to whether these may all have been part of a single syndrome, and the possible differential diagnosis is...
Ursodeoxycholic acid therapy in chronic active hepatitis.
A 41 year old woman developed chronic active hepatitis with prominent cholestasis. She was treated with prednisolone over 3 years with symptomatic benefit and improvement in serum biochemistry....
Hepatic abnormalities in coeliac disease: three cases of delayed diagnosis.
Mitchison, H. C., Record, C. O., Bateson, M. C., Cobden, I.
Three cases of biopsy-proven coeliac disease are presented. In each case the predominant clinical and laboratory features suggested liver disease, bowel symptoms were a minor part of the presentation...
Improving management of duodenal ulcer disease.
Audit of treatment of duodenal ulcer disease has allowed management to improve and keep abreast of rapid advances in care. Eradication of Helicobacter pylori was assessed by 14C urea breath test one...
Severe pulmonary disease and hyperviscosity in macroglobulinaemia.
A case of Waldenstrom's macroglobulinaemia with various clinical manifestations of the condition is presented. Hyperviscosity and respiratory complications are discussed with a brief review of the...