Brain Attending a Cocktail Party (2008)
Course Instructors Bertr, M. Christian Brown, Joe C. Adams, Kenneth E. Hancock, Frank H. Guenther, Jennifer R. Melcher, ...
Imagine after our topic presentation, we go to a crowded pub to celebrate. You are trying hard to ignore those eighties tunes blaring out of the loudspeakers while you are chatting with your...
Arnold, Jelena S., Braunstein, Evan M., Ohyama, Takahiro, Groves, Andrew K., Adams, Joe C., Brown, M. Christian, ...
Most 22q11.2 deletion syndrome (22q11DS) patients have middle and outer ear anomalies while some have inner ear malformations. Tbx1, a gene hemizygously deleted in 22q11DS patients and required for...
Arnold, Jelena S., Braunstein, Evan M., Ohyama, Takahiro, Groves, Andrew K., Adams, Joe C., Brown, M. Christian, ...
Most 22q11.2 deletion syndrome (22q11DS) patients have middle and outer ear anomalies, whereas some have inner ear malformations. Tbx1, a gene hemizygously deleted in 22q11DS patients and required...
Liao, Jun, Kochilas, Lazaros, Nowotschin, Sonja, Arnold, Jelena S., Aggarwal, Vimla S., Epstein, Jonathan A., ...
Velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS) is associated with de novo hemizygous 22q11.2 deletions and is characterized by malformations attributed to abnormal development of the...
Liao, Jun, Kochilas, Lazaros, Nowotschin, Sonja, Arnold, Jelena S., Aggarwal, Vimla S., Epstein, Jonathan A., ...
Velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS) is associated with de novo hemizygous 22q11.2 deletions and is characterized by malformations attributed to abnormal development of the...
Liao, Jun, Kochilas, Lazaros, Nowotschin, Sonja, Arnold, Jelena S., Aggarwal, Vimla S., Epstein, Jonathan A., ...
Velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS) is associated with de novo hemizygous 22q11.2 deletions and is characterized by malformations attributed to abnormal development of the...
HST.723 Neural Coding and Perception of Sound, Spring 2003 (2003)
Delgutte, Bertrand, Brown, Merritt Christian, Guinan, John Joseph, Melcher, Jennifer R., Oxenham, Andrew J., Brown, M. Christian, ...
Neural structures and mechanisms mediating the detection, localization, and recognition of sounds. Discussion of how acoustic signals are coded by auditory neurons, the impact of these codes on...
HST.723 Neural Coding and Perception of Sound, Spring 2003 (2003)
Delgutte, Bertrand, Brown, Merritt Christian, Guinan, John Joseph, Melcher, Jennifer R., Oxenham, Andrew J., Brown, M. Christian, ...
Neural structures and mechanisms mediating the detection, localization, and recognition of sounds. Discussion of how acoustic signals are coded by auditory neurons, the impact of these codes on...
Vascular Defects and Sensorineural Deafness in a Mouse Model of Norrie Disease (2002)
Rehm,Heidi L., Zhang,Duan-Sun, Brown,M. Christian, Burgess,Barbara, Halpin,Chris, Berger,Wolfgang, ...
Norrie disease is an X-linked recessive syndrome of blindness, deafness, and mental retardation. A knock-out mouse model with an Ndp gene disruption was studied. We examined the hearing phenotype,...
Vascular Defects and Sensorineural Deafness in a Mouse Model of Norrie Disease (2002)
Rehm, Heidi L., Zhang, Duan-Sun, Brown, M. Christian, Burgess, Barbara, Halpin, Chris, Berger, Wolfgang, ...
Norrie disease is an X-linked recessive syndrome of blindness, deafness, and mental retardation. A knock-out mouse model with an Ndp gene disruption was studied. We examined the hearing phenotype,...
Funke, Birgit, Epstein, Jonathan A., Kochilas, Lazaros K., Lu, Min Min, Pandita, Raj K., Liao, Jun, ...
Velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS) is a congenital anomaly disorder associated with hemizygous 22q11 deletions. We previously showed that bacterial artificial chromosome...
Anesthesia and surgical traum: their influence on the guinea pig compound action potential (1983)
Brown, M. Christian, Smith, D. Ian, Nuttall, Alfred L.
A chronic implant consisting of a fine thermocouple placed on the round window permitted measurement of temperature and of the compound action potential (CAP) of the cochlear nerve in guinea pigs....
Cochlear inner hair cells: Effects of transient asphyxia on intracellular potentials (1983)
Brown, M. Christian, Nuttall, Alfred L., Masta, Robert I., Lawrence, Merle
Intracellular potentials were recorded from inner hair cells in the guinea pig cochlea. Transient asphyxia was induced by interrupting respiration for brief periods. Asphyxia caused a...
Essential role of retinoblastoma protein in mammalian hair cell development and hearing
Sage, Cyrille, Huang, Mingqian, Vollrath, Melissa A., Brown, M. Christian, Hinds, Philip W., Corey, David P., ...
The retinoblastoma protein pRb is required for cell-cycle exit of embryonic mammalian hair cells but not for their early differentiation. However, its role in postnatal hair cells is unknown. To...
Essential role of retinoblastoma protein in mammalian hair cell development and hearing
Sage, Cyrille, Huang, Mingqian, Vollrath, Melissa A., Brown, M. Christian, Hinds, Philip W., Corey, David P., ...
The retinoblastoma protein pRb is required for cell-cycle exit of embryonic mammalian hair cells but not for their early differentiation. However, its role in postnatal hair cells is unknown. To...
Postsynaptic Targets of Type II Auditory Nerve Fibers in the Cochlear Nucleus.
Benson, Thane E., Brown, M. Christian
Type II auditory nerve fibers, which provide the primary afferent innervation of outer hair cells of the cochlea, project thin fibers centrally and form synapses in the cochlear nucleus. We...
Diverse Synaptic Terminals on Rat Stapedius Motoneurons
Lee, Daniel J., Benson, Thane E., Brown, M. Christian
Stapedius motoneurons (SMN) mediate the contraction of the stapedius muscle, which protects the inner ear from injury and reduces the masking effects of background noise. A variety of inputs to SMNs...