Oestrogens in rheumatic diseases: friend or foe? (2008)
Cutolo, M., Capellino, S., Straub, R. H.
Immunological and epidemiological evidences suggest that female sex hormones play an important role in the aetiology and pathophysiology of chronic inflammatory diseases; however, whether (or when)...
Jacobs, J Wg, Boers, M, Boumpas, D, Buttgereit, F, Caeyers, N, ...
OBJECTIVE: To develop evidence based recommendations for the management of systemic glucocorticoid (GC) therapy in rheumatic diseases. METHODS: The multidisciplinary guideline development group from...
Sarzi-Puttini, P., Atzeni, F., Schölmerich, J., Cutolo, M., Straub, R. H.
BACKGROUND: Insulin-like growth factor 1 (IGF1) is an important determinant of muscle mass because it promotes growth and suppresses protein degradation. IGF1 is decreased in rheumatoid arthritis and...
Härle, P., Straub, R. H., Wiest, R., Mayer, A., Schölmerich, J., Atzeni, F., ...
OBJECTIVE: To study in parallel the outflow of the sympathetic nervous system (SNS) and the hypothalamic-pituitary adrenal (HPA) axis tone in systemic lupus erythematosus (SLE) and rheumatoid...
Visceral leishmaniasis infection in a rheumatoid arthritis patient treated with adalimumab (2006)
Bassetti, M., Pizzorni, C., Gradoni, L., Del Bono, V., Cutolo, M., Viscoli, C.
Visceral leishmaniasis infection in a rheumatoid arthritis patient treated with adalimumab (2006)
Bassetti, M., Pizzorni, C., Gradoni, L., Del Bono, V., Cutolo, M., Viscoli, C.
Cutolo, M., Sulli, A., Secchi, M. E., Paolino, S., Pizzorni, C.
Raynaud's phenomenon (RP) represents the most frequent clinical aspect of cardio/microvascular involvement and is a key feature of several autoimmune rheumatic diseases. Moreover, RP is associated in...
Visceral leishmaniasis infection in a rheumatoid arthritis patient treated with adalimumab (2006)
Bassetti, M., Pizzorni, C., Gradoni, L., Del Bono, V., Cutolo, M., Viscoli, C.
Blunted coronary flow reserve in systemic sclerosis (2004)
Sulli, A., Ghio, M., Bezante, G. P., Deferrari, L., Craviotto, C., Sebastiani, V., ...
Objectives. We investigated whether the non-invasive determination of coronary flow reserve (CFR), as evaluated by transthoracic Doppler echocardiography, might be a potential method to detect early...
Nailfold videocapillaroscopic patterns and serum autoantibodies in systemic sclerosis (2004)
Cutolo, M., Pizzorni, C., Tuccio, M., Burroni, A., Craviotto, C., Basso, M., ...
Background. Microvascular lesions are a predominant feature in systemic sclerosis (SSc) and seem to play a central pathogenetic role. Recently, we graded scleroderma microangiopathy by nailfold...
Blunted coronary flow reserve in systemic sclerosis (2004)
Sulli, A., Ghio, M., Bezante, G. P., Deferrari, L., Craviotto, C., Sebastiani, V., ...
Objectives. We investigated whether the non-invasive determination of coronary flow reserve (CFR), as evaluated by transthoracic Doppler echocardiography, might be a potential method to detect early...
Nailfold videocapillaroscopic patterns and serum autoantibodies in systemic sclerosis (2004)
Cutolo, M., Pizzorni, C., Tuccio, M., Burroni, A., Craviotto, C., Basso, M., ...
Background. Microvascular lesions are a predominant feature in systemic sclerosis (SSc) and seem to play a central pathogenetic role. Recently, we graded scleroderma microangiopathy by nailfold...
Blunted coronary flow reserve in systemic sclerosis (2004)
Sulli, A., Ghio, M., Bezante, G. P., Deferrari, L., Craviotto, C., Sebastiani, V., ...
Objectives. We investigated whether the non-invasive determination of coronary flow reserve (CFR), as evaluated by transthoracic Doppler echocardiography, might be a potential method to detect early...
Nailfold videocapillaroscopic patterns and serum autoantibodies in systemic sclerosis (2004)
Cutolo, M., Pizzorni, C., Tuccio, M., Burroni, A., Craviotto, C., Basso, M., ...
Background. Microvascular lesions are a predominant feature in systemic sclerosis (SSc) and seem to play a central pathogenetic role. Recently, we graded scleroderma microangiopathy by nailfold...
Ottonello, L., Cutolo, M., Frumento, G., Arduino, N., Bertolotto, M., Mancini, M., ...
Objective. In synovial fluid (SF) from patients with rheumatoid arthritis (RA), neutrophils are exposed to proinflammatory mediators endowed with either anti‐apoptotic or...
Long-term treatment of patients affected by systemic sclerosis with cyclosporin A (2001)
Filaci, G., Cutolo, M., Basso, M., Murdaca, G., Derchi, L., Gianrossi, R., ...
Straub, R. H., Glück, T., Cutolo, M., Georgi, J., Helmke, K., Schölmerich, J., ...
Objectives. To determine the correlation between inflammatory cytokines and adrenal hormones in patients with polymyalgia rheumatica (PMR) and to compare the ratio of serum cortisol and...
Stress system response and rheumatoid arthritis: a multilevel approach (1999)
Walker, J. G., Littlejohn, G. O., McMurray, N. E., Cutolo, M.
A growing body of research indicates that the stress system, and its interactions with the immune system, play a pivotal role in the aetiology and progression of rheumatoid arthritis (RA). The stress...
Filaci, G., Cutolo, M., Scudeletti, M., Castagneto, C., Derchi, L., Gianrossi, R., ...
Objectives. The main aim was to analyse the long-term therapeutic effects on systemic sclerosis (SSc) patients of treatment with either (i) iloprost alone or (ii) low-dose oral cyclosporin A (CyA)...
Testosterone metabolism and cyclosporin A treatment in rheumatoid arthritis (1997)
Cutolo, M, Giusti, M, Villaggio, B, Barone, A, Accardo, S, Sulli, A, ...
M. Cutolo, S. Accardo, B. Villaggio, A. Barone, A. Sulli, E. Balleari, ...
The presence of androgen receptors on synovial macrophages in human normal and rheumatoid synovial tissues has been described previously. It is now reported that primary cultured human macrophages...
MACROAMYLASEMIA: A POSSIBLE CAUSE OF UNEXPLAINED HYPERAMYLASEMIA IN RHEUMATOID ARTHRITIS (1995)
CUTOLO, M., SULLI, A., BARONE, A., PICCIOTTO, A., MANGRAVTTI, S., SERIOLO, B., ...
Macroamylasemia is a benign acquired condition, characterized by a serum amylase unusually large in molecular size that has been found to occur in apparently healthy humans as well as in a variety of...
Buttgereit, F, Boers, M, Burmester, G, Cutolo, M, Jacobs, J, ...
In rheumatology and other medical specialties there is a discrepancy between the widespread use and the imprecise designation of glucocorticoid treatment regimens. Verbal descriptions of...
Cutolo, M, Sulli, A, Ghiorzo, P, Pizzorni, C, Craviotto, C, Villaggio, B
Background: Leflunomide and its active metabolite A77 1726 reversibly inhibits the enzyme dihydro-orotate dehydrogenase, the rate limiting step in de novo synthesis of pyrimidines and progression of...
Cutolo, M, Maestroni, G, Otsa, K, Aakre, O, Villaggio, B, Capellino, S, ...
Background: Altered functioning of the hypothalamic-pituitary-adrenal axis and altered melatonin production might modulate the circadian symptoms in patients with rheumatoid arthritis.
White matter hyperintensities on brain magnetic resonance in systemic sclerosis
Sardanelli, F, Iozzelli, A, Cotticelli, B, Losacco, C, Cutolo, M, Sulli, A, ...
Methods: Fourteen female patients with SSc aged 24–74, with a disease duration of 1–12 years and without other relevant systemic diseases, were enrolled. All patients and an age matched female...
Cutolo, M., Accardo, S., Villaggio, B., Barone, A., Sulli, A., Balleari, E., ...
The presence of androgen receptors on synovial macrophages in human normal and rheumatoid synovial tissues has been described previously. It is now reported that primary cultured human macrophages...
Straub, R, Sarzi-Puttini, P, Atzeni, F, Buttgereit, F, Carrabba, M, Cutolo, M
Objective: To investigate the course of CBG during anti-TNF treatment in RA.
Härle*, P, Straub*, R H, Wiest, R, Mayer, A, Schölmerich, J, Atzeni, F, ...
Jacobs, J W G, Kirwan, J R, Boers, M, Saag, K G, Inês, L B S, ...
Adverse effects of glucocorticoids have been abundantly reported. Published reports on low dose glucocorticoid treatment show that few of the commonly held beliefs about their incidence, prevalence,...