Effects of Genetic Perturbation on Seasonal Life History Plasticity (2009)
Wilczek, A M, Roe, J L, Knapp, M C, Cooper, M D, Lopez-Gallego, C, Martin, L. J., ...
Effects of Genetic Perturbation on Seasonal Life History Plasticity (2009)
Wilczek, A. M., Roe, J. L., Knapp, M. C., Cooper, M. D., Lopez-Gallego, C., Martin, L. J., ...
Interactions between housed dairy cows during feeding, lying and standing (2008)
Cooper, M.D., Arney, D.R., Webb, C.R., Phillips, Clive J.C.
Three experiments examined the extent of behavioral interactions between housed dairy cows. In Experiment 1, 6 different cows were selected every other day from a dairy herd and allocated to 3 pairs...
Long, J. C., Barnes, P. D., Boissevain, J. G., Clark, D. J., Cooper, M. D., Gomez, J. J., ...
A new search for a permanent electric dipole moment (EDM) of the neutron is underway using ultracold neutrons produced and held in a bath of superfluid helium. Attaining the target sensitivity...
Abbasi, R. U., Abu-Zayyad, T., Amman, J. F., Archbold, G. C., Caceres, J. A. Bellido, Belov, K., ...
Copyright © 2005 Elsevier B.V. All rights reserved.
Abbasi, R. U., Abu-Zayyad, T., Amman, J. F., Archbold, G. C., Caceres, J. A. Bellido, Belov, K., ...
Copyright © 2005 Elsevier B.V. All rights reserved.
Abu-Zayyad, T, Amann, J F, Archbold, G, Bellido, J A, Belov, K, ...
We have measured the cosmic ray spectrum above 10(17.2) eV using the two air-fluorescence detectors of the High Resolution Fly's Eye observatory operating in monocular mode. We describe the detector,...
Abbasi, R., Abu-Zayyad, T., Amann, J. F., Archbold, G. C., Caceres, J. A. Bellido, Belov, K., ...
© 2004 The American Physical Society
Search for global dipole enhancements in the HiRes-I monocular data above 1018.5 eV (2004)
Abbasi, R. U., Abu-Zayyad, T., Amann, J. F., Archbold, G. C., Caceres, J. A. Bellido, Belov, K., ...
Copyright © 2004 Elsevier B.V. All rights reserved.
Aminopeptidase A is a functional target in angiogenic blood vessels (2004)
Marchio, S., Lahdenranta, J., Schlingemann, R.O., Valdembri, D., Wesseling, P., Arap, M.A., ...
Abbasi, R., Abu-Zayyad, T., Amann, J. F., Archbold, G. C., Caceres, J. A. Bellido, Belov, K., ...
© 2004 The American Physical Society
Search for global dipole enhancements in the HiRes-I monocular data above 1018.5 eV (2004)
Abbasi, R. U., Abu-Zayyad, T., Amann, J. F., Archbold, G. C., Caceres, J. A. Bellido, Belov, K., ...
Copyright © 2004 Elsevier B.V. All rights reserved.
Identification and characterization of a TAP-family gene in the lamprey (2003)
Uinuk-ool, T. S., Mayer, W. E., Sato, A., Takezaki, N., Benyon, L., Cooper, M. D., ...
Isolation and characterization of lymphocyte-like cells from a lamprey (2002)
Mayer, W. E., Uinuk-ool, T., Tichy, H., Gartland, L. A., Klein, J., Cooper, M. D.
Lymphocyte-like cells in the intestine of the sea lamprey, Petromyzon marinus, were isolated by flow cytometry under light-scatter conditions used for the purification of mouse intestinal...
Uinuk-ool, T., Mayer, W. E., Sato, A., Dongak, R., Cooper, M. D., Klein, J.
To shed light on the origin of adaptive immunity, a cDNA library was prepared from purified lymphocyte-like cells of a jawless vertebrate, the sea lamprey (Petromyzon marinus). Randomly selected cDNA...
Lamoreaux, S. K., Archibald, G., Barnes, P. D., Buttler, W. T., Clark, D. J., Cooper, M. D., ...
We have measured the mass diffusion coefficient D of 3He in superfluid 4He at temperatures lower than were previously possible. The experimental technique utilizes scintillation light produced when...
New Limit for the Family-Number Non-conserving Decay mu+ to e+_gamma (1999)
Chen, Y. K., Cooper, M. D., Cooper, P. S., Dzemidzic, M., Empl, A., ...
An experiment has been performed to search for the muon- and electron-number non-conserving decay mu+ to e+_gamma. The upper limit for the branching ratio to be GAMMA(mu+ to e+_gamma)/GAMMA(mu+ to...
Macromolecular modelling on the Cray T3D (1999)
Cooper, M D, Goodfellow, J M, Hillier, I H, Reynolds, C A, Richards, W G, Robb, M A, ...
MEGA: a search for the rare decay $\mu$ --> e$\gamma$ at the level of 5 x 10$^{-13}$ (1993)
Amann, J F, Barakat, M B, Barlow, D, Black, K, Bolton, R D, Carius, S, ...
Von Beust, B, Niederer, E, Condrau, M A, Fierz, W, ...
In a previous experiment a group of 15 specified pathogen free (SPF) cats were experimentally infected with a Swiss isolate of feline immunodeficiency virus (FIV). A group of 15 SPF cats served as...
Typescript (photocopy).
A pi0 and eta spectrometer of lead glass and BGO for momenta up to 1 GeV/c (1990)
Adiels, L, Backenstoss, Gerhard, Bergström, I, Carius, S, Charalambous, S, Cooper, M D, ...
Search for narrow signals in the gamma-spectrum from p$\overline{p}$ annihilation at rest (1990)
Adiels, L, Backenstoss, Gerhard, Bergström, I, Carius, S, Charalambous, S, Cooper, M D, ...
Kerr, W. G., Cooper, M. D., Feng, L., Burrows, P. D., Hendershot, L. M., Watanabe, Takeshi
In pre-B cells, the earliest identiflable stage of B cell differentiation, there is an asynchrony of Immunoglobulin chain expression in that μ heavy chains are synthesized in the absence of light...
Thesis (doctoral)--University of Birmingham, 1983.
Switch recombination in normal IgA1+ B lymphocytes.
Irsch, J, Irlenbusch, S, Radl, J, Burrows, P D, Cooper, M D, Radbruch, A H
Most B lymphocytes in normal individuals express two classes of cell-surface immunoglobulins, IgM and IgD. The specificity of the two antigen receptors is identical since they are produced by...
Identification of the TCL1 gene involved in T-cell malignancies.
Virgilio, L, Narducci, M G, Isobe, M, Billips, L G, Cooper, M D, Croce, C M, ...
The TCL1 locus on chromosome 14q32.1 is frequently involved in chromosomal translocations and inversions with one of the T-cell receptor loci in human T-cell leukemias and lymphomas. The chromosome...
Histidine residue in the zinc-binding motif of aminopeptidase A is critical for enzymatic activity.
The murine BP-1 antigen (also called 6C3) is a homodimeric, phosphorylated cell surface glycoprotein that is expressed on immature B-lineage cells, bone marrow stromal cell lines, thymic cortical...
Nakamura, T, Kubagawa, H, Cooper, M D
Two covalently linked transmembrane molecules, encoded in mice by the mb-1 and B29 genes, have been defined as integral components of the antibody receptor units expressed on B cells. We have...
Aminopeptidase A activity of the murine B-lymphocyte differentiation antigen BP-1/6C3.
Wu, Q, Li, L, Cooper, M D, Pierres, M, Gorvel, J P
The predicted amino acid sequence of the cDNA encoding the murine B-lymphocyte differentiation antigen BP-1/6C3 suggested that it is a member of the zinc-dependent metalloprotease family, possibly an...
Normal pre-B cells express a receptor complex of mu heavy chains and surrogate light-chain proteins.
Nishimoto, N, Kubagawa, H, Ohno, T, Gartland, G L, Stankovic, A K, Cooper, M D
Precursors of B cells, which constitute a subpopulation of the lymphocytes in bone marrow, can be identified by their surface expression of nonimmunoglobulin markers and the absence of immunoglobulin...
T cells expressing the V beta 1 T-cell receptor are required for IgA production in the chicken.
Cihak, J, Hoffmann-Fezer, G, Ziegler-Heibrock, H W, Stein, H, Kaspers, B, Chen, C H, ...
While alpha beta T cells in mammals may express one of many variable (V) gene families in the beta locus, chickens have only two V beta gene families. The avian V beta 2+ T cells are recognized by...
Lahti, J M, Chen, C L, Tjoelker, L W, Pickel, J M, Schat, K A, Calnek, B W, ...
Avian T cells can be divided into three subpopulations based on their expression of distinct T-cell receptors (TCR1, TCR2, and TCR3), ontogeny, and tissue distribution. The TCR1 cells appear to be...
Wu, Q, Lahti, J M, Air, G M, Burrows, P D, Cooper, M D
The BP-1/6C3 antigen is a phosphorylated cell surface glycoprotein that can be identified by monoclonal antibodies on mouse pre-B cells, immature B cells, and certain stromal cell lines from bone...
Evolutionary conservation of antigen recognition: the chicken T-cell receptor beta chain.
Tjoelker, L W, Carlson, L M, Lee, K, Lahti, J, McCormack, W T, Leiden, J M, ...
T cells play important regulatory roles in the immune responses of vertebrates. Antigen-specific T-cell activation involves T-cell receptor (TCR) recognition of a peptide antigen presented by a major...
Quackenbush, S L, Donahue, P R, Dean, G A, Myles, M H, Ackley, C D, Cooper, M D, ...
The FeLV-FAIDS strain of feline leukemia virus consistently induces fatal immunodeficiency. To investigate the immunopathogenesis and viral genetic determinants responsible for the induction of...
Ackley, C D, Yamamoto, J K, Levy, N, Pedersen, N C, Cooper, M D
Blood mononuclear cells from 47 cats experimentally infected with feline immunodeficiency virus (FIV) were examined by using monoclonal antibodies directed against feline CD4 and CD8 homologs, a...
Cooper, M D, McGraw, P A, Melly, M A
An experimental model using human fallopian tubes in organ culture was used to study the localization of purified gonococcal lipopolysaccharide (LPS). LPS was visualized by light microscopy with...
Kubagawa, H, Burrows, P D, Grossi, C E, Mestecky, J, Cooper, M D
Human bone marrow cells were depleted of B lymphocytes to enrich for precursor B cells that could be transformed with Epstein-Barr virus. Transformed immunoglobulin-negative precursors either...
TCR3: a third T-cell receptor in the chicken.
Chen, C H, Sowder, J T, Lahti, J M, Cihak, J, Lösch, U, Cooper, M D
Avian homologues of mammalian gamma delta and alpha beta T-cell antigen receptors, TCR1 and TCR2, have been identified with monoclonal antibodies. These TCR isotypes are associated with the avian CD3...
Kubagawa, H, Cooper, M D, Carroll, A J, Burrows, P D
Epstein-Barr virus transformation of B-cell-depleted bone marrow cells from human fetuses allowed us to identify novel cell types characterized by the expression of immunoglobulin kappa or lambda...
Monteiro, R C, Hostoffer, R W, Cooper, M D, Bonner, J R, Gartland, G L, Kubagawa, H
Fc alpha receptors (Fc alpha R), detected by the binding of IgA and by anti-Fc alpha R antibodies, were found to be differentially expressed on eosinophils and neutrophils. Neutrophils were the major...
Volanakis, J E, Zhu, Z B, Schaffer, F M, Macon, K J, Palermos, J, Barger, B O, ...
We have proposed that significant subsets of individuals with IgA deficiency (IgA-D) and common variable immunodeficiency (CVID) may represent polar ends of a clinical spectrum reflecting a single...
Schaffer, F M, Palermos, J, Zhu, Z B, Barger, B O, Cooper, M D, Volanakis, J E
IgA deficiency and common variable immunodeficiency are heritable disorders that can occur within the same family. Both immunodeficiencies are characterized by arrests in B-cell differentiation that...
Differentiation Capacity of Cultured B Lymphocytes from Immunodeficient Patients
Wu, L. Y. F., Lawton, A. R., Cooper, M. D.
Peripheral blood lymphocytes from 27 healthy individuals and from 18 patients with a diverse spectrum of defects in humoral immunity were examined for their capacity to undergo terminal...
Peault, B, Chen, C L, Cooper, M D, Barbu, M, Lipinski, M, Le Douarin, N M
The HNK-1 (Leu 7) and NC-1 monoclonal antibodies, raised against a human T-cell line and against nerve cells of quail embryos, respectively, have been shown to bind to a shared epitope present on the...
Wannemuehler, M J, Miller, R D, Cooper, M D
Immunization of guinea pigs with ribosomal preparations has been previously shown to be protective against chamber infection with Neisseria gonorrhoeae, and this protection could be correlated with...
Cooper, M D, Wannemuehler, M J, Miller, R D, Fedyk, M F
A recent report (Cooper et al., Infect. Immun. 28:92-100, 1980) demonstrated that immunization of guinea pigs with ribosomal preparations was protective (approximately 90%) against chamber infections...
Unstimulated resident peritoneal macrophages were harvested from complement-sufficient (C5+) and complement-deficient (C5-) mice by peritoneal lavage and cultured for 14 h. Adherence to cover slips...
Synergistic Effects of Ampicillin-Aminoglycoside Combinations on Group B Streptococci
Cooper, M. D., Keeney, R. E., Lyons, S. F., Cheatle, E. L.
The in vitro activity of gentamicin, tobramycin, kanamycin, and amikacin in combination with ampicillin was determined against aminoglycoside-resistant group B streptococci. Synergy in each...
Abo, T, Roder, J C, Abo, W, Cooper, M D, Balch, C M
Children with the Chediak-Higashi (CH) syndrome are known to have abnormalities of natural killer (NK) cell function. We used the HNK-1 monoclonal antibody that reacts specifically with human NK and...
Hyper IgM immunodeficiency. A primary dysfunction of B lymphocyte isotype switching.
Levitt, D, Haber, P, Rich, K, Cooper, M D
Immunological evaluations (lymphocyte markers, B cell differentiation, T cell function) were performed on peripheral blood mononuclear cells from four individuals with hyper IgM immunodeficiency....
Abnormalities of T cell maturation and regulation in human beings with immunodeficiency disorders.
Reinherz, E L, Cooper, M D, Schlossman, S F, Rosen, F S
A series of monoclonal antibodies to T cell surface antigens were used to characterize peripheral lymphoid populations from patients with a variety of immunodeficiency diseases. Several disorders of...
Conley, M E, Cooper, M D, Michael, A F
To further characterize the IgA deposits found in glomeruli of patients with IgA nephropathy, anaphylactoid purpura nephritis, and systemic lupus erythematosus, renal biopsies from patients with...
Webb, C F, Cooper, M D, Burrows, P D, Griffin, J A
During differentiation B lymphocytes may switch from the expression of surface IgM to the synthesis of IgG, IgA, or IgE isotypes by using a different heavy chain constant region (CH) gene. The...
T cell migration during development: homing is not related to TCR V beta 1 repertoire selection.
Dunon, D, Schwager, J, Dangy, J P, Cooper, M D, Imhof, B A
T cell precursors enter the chick thymus in three waves during embryonic life. Each wave of thymocyte precursors colonizing the thymus gave rise to a similar TCR V beta repertoire in thymus, spleen...
Landay, A, Poon, M C, Abo, T, Stagno, S, Lurie, A, Cooper, M D
Asymptomatic hemophilia patients receiving Factor VIII concentrate were found to have normal natural killer (NK) cells and B cells, and an inverted T helper/suppressor ratio due to an increase in...
Identification of T-cell receptor alpha-chain genes in the chicken.
Göbel, T W, Chen, C L, Lahti, J, Kubota, T, Kuo, C L, Aebersold, R, ...
T-cell receptor (TCR) alpha-chain (TCR alpha) and beta-chain (TCR beta) genes are well characterized in mammals, while only TCR beta genes have been identified in other vertebrates. To identify avian...
Immunogenicity of ribosomal preparations from Neisseria gonorrhoeae.
Cooper, M D, Tewari, R P, Bowser, D V
Protection against gonococcal infection was obtained by immunization with ribosomal preparations from Neisseria gonorrhoeae. Ribosomes were isolated from disrupted cells by differential...
Switch recombination in normal IgA1+ B lymphocytes.
Irsch, J, Irlenbusch, S, Radl, J, Burrows, P D, Cooper, M D, Radbruch, A H
Most B lymphocytes in normal individuals express two classes of cell-surface immunoglobulins, IgM and IgD. The specificity of the two antigen receptors is identical since they are produced by...
Identification of the TCL1 gene involved in T-cell malignancies.
Virgilio, L, Narducci, M G, Isobe, M, Billips, L G, Cooper, M D, Croce, C M, ...
The TCL1 locus on chromosome 14q32.1 is frequently involved in chromosomal translocations and inversions with one of the T-cell receptor loci in human T-cell leukemias and lymphomas. The chromosome...
Histidine residue in the zinc-binding motif of aminopeptidase A is critical for enzymatic activity.
The murine BP-1 antigen (also called 6C3) is a homodimeric, phosphorylated cell surface glycoprotein that is expressed on immature B-lineage cells, bone marrow stromal cell lines, thymic cortical...
Nakamura, T, Kubagawa, H, Cooper, M D
Two covalently linked transmembrane molecules, encoded in mice by the mb-1 and B29 genes, have been defined as integral components of the antibody receptor units expressed on B cells. We have...
Aminopeptidase A activity of the murine B-lymphocyte differentiation antigen BP-1/6C3.
Wu, Q, Li, L, Cooper, M D, Pierres, M, Gorvel, J P
The predicted amino acid sequence of the cDNA encoding the murine B-lymphocyte differentiation antigen BP-1/6C3 suggested that it is a member of the zinc-dependent metalloprotease family, possibly an...
Normal pre-B cells express a receptor complex of mu heavy chains and surrogate light-chain proteins.
Nishimoto, N, Kubagawa, H, Ohno, T, Gartland, G L, Stankovic, A K, Cooper, M D
Precursors of B cells, which constitute a subpopulation of the lymphocytes in bone marrow, can be identified by their surface expression of nonimmunoglobulin markers and the absence of immunoglobulin...
T cells expressing the V beta 1 T-cell receptor are required for IgA production in the chicken.
Cihak, J, Hoffmann-Fezer, G, Ziegler-Heibrock, H W, Stein, H, Kaspers, B, Chen, C H, ...
While alpha beta T cells in mammals may express one of many variable (V) gene families in the beta locus, chickens have only two V beta gene families. The avian V beta 2+ T cells are recognized by...
Lahti, J M, Chen, C L, Tjoelker, L W, Pickel, J M, Schat, K A, Calnek, B W, ...
Avian T cells can be divided into three subpopulations based on their expression of distinct T-cell receptors (TCR1, TCR2, and TCR3), ontogeny, and tissue distribution. The TCR1 cells appear to be...
Wu, Q, Lahti, J M, Air, G M, Burrows, P D, Cooper, M D
The BP-1/6C3 antigen is a phosphorylated cell surface glycoprotein that can be identified by monoclonal antibodies on mouse pre-B cells, immature B cells, and certain stromal cell lines from bone...
Evolutionary conservation of antigen recognition: the chicken T-cell receptor beta chain.
Tjoelker, L W, Carlson, L M, Lee, K, Lahti, J, McCormack, W T, Leiden, J M, ...
T cells play important regulatory roles in the immune responses of vertebrates. Antigen-specific T-cell activation involves T-cell receptor (TCR) recognition of a peptide antigen presented by a major...
Quackenbush, S L, Donahue, P R, Dean, G A, Myles, M H, Ackley, C D, Cooper, M D, ...
The FeLV-FAIDS strain of feline leukemia virus consistently induces fatal immunodeficiency. To investigate the immunopathogenesis and viral genetic determinants responsible for the induction of...
Ackley, C D, Yamamoto, J K, Levy, N, Pedersen, N C, Cooper, M D
Blood mononuclear cells from 47 cats experimentally infected with feline immunodeficiency virus (FIV) were examined by using monoclonal antibodies directed against feline CD4 and CD8 homologs, a...
Cooper, M D, McGraw, P A, Melly, M A
An experimental model using human fallopian tubes in organ culture was used to study the localization of purified gonococcal lipopolysaccharide (LPS). LPS was visualized by light microscopy with...
Kubagawa, H, Burrows, P D, Grossi, C E, Mestecky, J, Cooper, M D
Human bone marrow cells were depleted of B lymphocytes to enrich for precursor B cells that could be transformed with Epstein-Barr virus. Transformed immunoglobulin-negative precursors either...
TCR3: a third T-cell receptor in the chicken.
Chen, C H, Sowder, J T, Lahti, J M, Cihak, J, Lösch, U, Cooper, M D
Avian homologues of mammalian gamma delta and alpha beta T-cell antigen receptors, TCR1 and TCR2, have been identified with monoclonal antibodies. These TCR isotypes are associated with the avian CD3...
Kubagawa, H, Cooper, M D, Carroll, A J, Burrows, P D
Epstein-Barr virus transformation of B-cell-depleted bone marrow cells from human fetuses allowed us to identify novel cell types characterized by the expression of immunoglobulin kappa or lambda...
Monteiro, R C, Hostoffer, R W, Cooper, M D, Bonner, J R, Gartland, G L, Kubagawa, H
Fc alpha receptors (Fc alpha R), detected by the binding of IgA and by anti-Fc alpha R antibodies, were found to be differentially expressed on eosinophils and neutrophils. Neutrophils were the major...
Volanakis, J E, Zhu, Z B, Schaffer, F M, Macon, K J, Palermos, J, Barger, B O, ...
We have proposed that significant subsets of individuals with IgA deficiency (IgA-D) and common variable immunodeficiency (CVID) may represent polar ends of a clinical spectrum reflecting a single...
Schaffer, F M, Palermos, J, Zhu, Z B, Barger, B O, Cooper, M D, Volanakis, J E
IgA deficiency and common variable immunodeficiency are heritable disorders that can occur within the same family. Both immunodeficiencies are characterized by arrests in B-cell differentiation that...
Differentiation Capacity of Cultured B Lymphocytes from Immunodeficient Patients
Wu, L. Y. F., Lawton, A. R., Cooper, M. D.
Peripheral blood lymphocytes from 27 healthy individuals and from 18 patients with a diverse spectrum of defects in humoral immunity were examined for their capacity to undergo terminal...
Peault, B, Chen, C L, Cooper, M D, Barbu, M, Lipinski, M, Le Douarin, N M
The HNK-1 (Leu 7) and NC-1 monoclonal antibodies, raised against a human T-cell line and against nerve cells of quail embryos, respectively, have been shown to bind to a shared epitope present on the...
Wannemuehler, M J, Miller, R D, Cooper, M D
Immunization of guinea pigs with ribosomal preparations has been previously shown to be protective against chamber infection with Neisseria gonorrhoeae, and this protection could be correlated with...
Cooper, M D, Wannemuehler, M J, Miller, R D, Fedyk, M F
A recent report (Cooper et al., Infect. Immun. 28:92-100, 1980) demonstrated that immunization of guinea pigs with ribosomal preparations was protective (approximately 90%) against chamber infections...
Unstimulated resident peritoneal macrophages were harvested from complement-sufficient (C5+) and complement-deficient (C5-) mice by peritoneal lavage and cultured for 14 h. Adherence to cover slips...
Synergistic Effects of Ampicillin-Aminoglycoside Combinations on Group B Streptococci
Cooper, M. D., Keeney, R. E., Lyons, S. F., Cheatle, E. L.
The in vitro activity of gentamicin, tobramycin, kanamycin, and amikacin in combination with ampicillin was determined against aminoglycoside-resistant group B streptococci. Synergy in each...
Abo, T, Roder, J C, Abo, W, Cooper, M D, Balch, C M
Children with the Chediak-Higashi (CH) syndrome are known to have abnormalities of natural killer (NK) cell function. We used the HNK-1 monoclonal antibody that reacts specifically with human NK and...
Hyper IgM immunodeficiency. A primary dysfunction of B lymphocyte isotype switching.
Levitt, D, Haber, P, Rich, K, Cooper, M D
Immunological evaluations (lymphocyte markers, B cell differentiation, T cell function) were performed on peripheral blood mononuclear cells from four individuals with hyper IgM immunodeficiency....
Abnormalities of T cell maturation and regulation in human beings with immunodeficiency disorders.
Reinherz, E L, Cooper, M D, Schlossman, S F, Rosen, F S
A series of monoclonal antibodies to T cell surface antigens were used to characterize peripheral lymphoid populations from patients with a variety of immunodeficiency diseases. Several disorders of...
Conley, M E, Cooper, M D, Michael, A F
To further characterize the IgA deposits found in glomeruli of patients with IgA nephropathy, anaphylactoid purpura nephritis, and systemic lupus erythematosus, renal biopsies from patients with...
Webb, C F, Cooper, M D, Burrows, P D, Griffin, J A
During differentiation B lymphocytes may switch from the expression of surface IgM to the synthesis of IgG, IgA, or IgE isotypes by using a different heavy chain constant region (CH) gene. The...
T cell migration during development: homing is not related to TCR V beta 1 repertoire selection.
Dunon, D, Schwager, J, Dangy, J P, Cooper, M D, Imhof, B A
T cell precursors enter the chick thymus in three waves during embryonic life. Each wave of thymocyte precursors colonizing the thymus gave rise to a similar TCR V beta repertoire in thymus, spleen...
Landay, A, Poon, M C, Abo, T, Stagno, S, Lurie, A, Cooper, M D
Asymptomatic hemophilia patients receiving Factor VIII concentrate were found to have normal natural killer (NK) cells and B cells, and an inverted T helper/suppressor ratio due to an increase in...
Identification of T-cell receptor alpha-chain genes in the chicken.
Göbel, T W, Chen, C L, Lahti, J, Kubota, T, Kuo, C L, Aebersold, R, ...
T-cell receptor (TCR) alpha-chain (TCR alpha) and beta-chain (TCR beta) genes are well characterized in mammals, while only TCR beta genes have been identified in other vertebrates. To identify avian...
Immunogenicity of ribosomal preparations from Neisseria gonorrhoeae.
Cooper, M D, Tewari, R P, Bowser, D V
Protection against gonococcal infection was obtained by immunization with ribosomal preparations from Neisseria gonorrhoeae. Ribosomes were isolated from disrupted cells by differential...
Haire, R N, Ohta, Y, Strong, S J, Litman, R T, Liu, Y, Prchal, J T, ...
Seven individuals with the diagnosis of X-linked agammaglobulinemia were analyzed for mutations in Bruton tyrosine kinase (Btk) gene at both the cDNA transcript and genomic DNA levels. In addition,...
Quere, P, Cooper, M D, Thorbecke, G J
Suppressor activity of chicken T cells has been previously defined in an in vitro assay of the secondary response of spleen cells to sheep erythrocytes. We have used this assay to examine the...
Su, D M, Wang, J, Lin, Q, Cooper, M D, Watanabe, T
Type 1 interferons (IFN-alpha/beta) have recently been shown to inhibit interleukin-7 (IL-7)-induced growth and survival of early B-lineage cells. The CD3- CD4- CD8- (triple negative; TN) thymocytes...
Lucivero, G, Lawton, A R, Cooper, M D
Our studies indicate that rosette formation with mouse erythrocytes defines a subpopulation of human B lymphocytes positive for both sIgM, sIgD and C3 receptors but largely negative for IgG Fc...
Luzi, G, Kubagawa, H, Crain, M J, Cooper, M D
IgA deficient individuals may also have low serum levels of IgG subclasses, especially IgG2. In the present study we examined the development of plasma cells producing IgM, IgA or IgG, and the IgG1...
A two-stage model for development of antibody-producing cells
Cooper, M. D., Lawton, A. R., Kincade, P. W.
This model divides plasma cell differentiation into two developmental stages within the framework of the clonal selection theory. The first stage occurs within specific induction micro-environments,...
Stroud, R. M., Nagaki, K., Pickering, R. J., Gewurz, H., Good, R. A., Cooper, M. D.
Normal concentrations of C1 esterase, C1s, have been found in nineteen individuals with a variety of immunologic deficiency syndromes. C1q levels are markedly low in patients with lymphopenic...
JOHNSON, M L, KEETON, L G, ZHU, Z-B, VOLANAKIS, J E, COOPER, M D, SCHROEDER, H W
The concentration of serum immunoglobulins in individuals with IgA deficiency (IgAD) and CVID can vary with age to have practical implications for evaluation, therapy, and genetic analysis. Most IgAD...
Cucca, F, Zhu, Z-B, Khanna, A, Cossu, F, Congia, M, Badiali, M, ...
IgA deficiency (IgA-D) has been associated with the HLA region, in particular with the North European haplotype HLA-A1, -B8, -DR3, but the exact location of the susceptibility gene(s) is unknown....
Clonal hematopoiesis and acquired thalassemia in common variable immunodeficiency.
Belickova, M., Schroeder, H. W., Guan, Y. L., Brierre, J., Berney, S., Cooper, M. D., ...
BACKGROUND: Common variable immunodeficiency (CVID) is defined by hypogammaglobulinemia and increased susceptibility to infections. The gene defect responsible for CVID remains unknown. METHODS:...
Schroeder, H. W., Zhu, Z. B., March, R. E., Campbell, R. D., Berney, S. M., Nedospasov, S. A., ...
BACKGROUND: A common genetic basis for IgA deficiency (IgAD) and common variable immunodeficiency (CVID) is suggested by their occurrence in members of the same family and the similarity of the...
Immunological profile in a chromosome 18 deletion syndrome with IgA deficiency.
Finley, S C, Cooper, M D, Finley, W H, Uchida, I A, Noto, T A, Roddam, R F
Dunon, D., Courtois, D., Vainio, O., Six, A., Chen, C.H., Cooper, M.D., ...
The embryonic thymus is colonized by the influx of hemopoietic progenitors in waves. To characterize the T cell progeny of the initial colonization waves, we used intravenous adoptive transfer of...