High-dose acetylcysteine in idiopathic pulmonary fibrosis (2005)
Demedts, M., Behr, J., Buhl, R., Costabel, U., Dekhuijzen, R., Jansen, H.M., ...
Thomeer, M J, Debrock, A J T, ...
BACKGROUND: Skeletal muscle weakness is assumed to be present in patients with sarcoidosis but has never been reported in a consecutive group of patients. Moreover, its relationship with previously...
We have investigated the effect of IL-1beta on histamine H(1)-receptor (H(1)R)-mediated inositol phosphate (IP) accumulation in human airway smooth muscle cells (HASMC) and on histamine-induced...
The effects of 5-HT on cholinergic contraction in human airways in vitro (1999)
Inhaled 5-hydroxytryptamine (5-HT) causes bronchoconstriction in asthmatics, and 5-HT plasma levels are elevated in asthma. Electrical field stimulation (EFS) of human airways, in vitro, evokes...
Pype, J L, Meade, C J, DeLeyn, P, Demedts, M, ...
Epinastine is an antihistamine drug with binding affinities at 5-hydroxytryptamine (5-HT) receptors. The current study was performed to investigate whether epinastine could modulate the cholinergic...
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We have demonstrated that, in addition to their contractile function, human airway smooth-muscle cells (HASMC) are able to express and to secrete chemokines of the monocyte chemotactic protein (MCP)/...
Electrical field stimulation of guinea pig tracheal strips and human bronchial rings, in vitro, evokes a cholinergic contraction mediated by the release of acetylcholine....
Stroobants, S G, Dupont, P J, Maes, Alex; U0032501, ...
PURPOSE: To compare the accuracy of computed tomography-(CT) scan and the radiolabeled glucose analog 18F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) visually correlated with CT...
Hemolytic-uremic syndrome caused by gemcitabine (1998)
Nackaerts, K., Daenen, M., Vansteenkiste, J., Van-develde, A., Van Bleyenbergh, P., Demedts, M.
Hemolytic-uremic syndrome caused by gemcitabine (1998)
Nackaerts, K., Daenen, M., Vansteenkiste, J., Vandevelde, A., Van Bleyenbergh, P., Demedts, M.
Verapamil as prophylactic treatment for atrial fibrillation after lung operations (1996)
VAN MIEGHEM, Walter, Tits, G., Demuynck, K., Lacquet, L., Deneffe, G., Tjandra-maga, T., ...
Verapamil as prophylactic treatment for atrial fibrillation after lung operations (1996)
VAN MIEGHEM, Walter, Tits, G., Demuynck, K., Lacquet, L., Deneffe, G., Tjandra-maga, T., ...
Effect of loop diuretics on cholinergic neurotransmission in human airways in vitro (1994)
BACKGROUND--Frusemide can inhibit various indirectly acting bronchoconstrictor stimuli in asthmatic patients. Both frusemide and bumetanide also modulate airway neurotransmission in some species but...
VERLEDEN, G, DEMEDTS, M, VAN MIEGHEM, Walter
Acute pulmonary oedema with normal pulmonary capillary wedge pressure, occurred in 2 patients with primary pulmonary hypertension, probably due to veno-occlusive diseases. In both cases an increase...
VERLEDEN, G, DEMEDTS, M, VAN MIEGHEM, Walter
Acute pulmonary oedema with normal pulmonary capillary wedge pressure, occurred in 2 patients with primary pulmonary hypertension, probably due to veno-occlusive diseases. In both cases an increase...
Auwerx, J, Boogaerts, M, Ceuppens, J L, Demedts, M
An extensive in vitro investigation of the host defence system was performed in 11 sibs of a large kindred with unexplained combination of familial hypocalciuric hypercalcaemia (FHH), interstitial...
Auwerx, J, Demedts, M, Bouillon, R, Desmet, J
In a prospective investigation, a large kindred (twenty-one subjects) with unexplained association of familial hypocalciuric hypercalcaemia and idiopathic interstitial lung disease was studied. Serum...
Demedts, M, Auwerx, J, Goddeeris, P, Bouillon, R, Gyselen, A, Lauweryns, J
The history and pulmonary histopathology of 3 siblings, presenting with the association of idiopathic interstitial lung disease, hypocalciuric hypercalcemia, and an intrinsic defect in granulocyte...
Cobalt-induced bronchial asthma in diamond polishers. (1985)
Gheysens, B, Auwerx, J, Demedts, M
Three diamond workers had occupational asthma attributed to the inhalation of cobalt powder. The exposure originated from high speed polishing disks with an abrasive consisting of microdiamonds...
Altered parathyroid set point to calcium in familial hypocalciuric hypercalcaemia. (1984)
Auwerx, J, Demedts, M, Bouillon, R
Changes in calcium concentration were induced by an infusion of disodium-EDTA or calcium in 2 members of a family suffering from hypocalciuric hypercalcaemia ( FHH ) associated with interstitial lung...
Auwerx, J, Boogaerts, M, Ceuppens, J L, Demedts, M
An extensive in vitro investigation of the host defence system was performed in 11 sibs of a large kindred with unexplained combination of familial hypocalciuric hypercalcaemia (FHH), interstitial...
Bronchoalveolar lavage findings in a patient with the organic dust toxic syndrome.
Raymenants, E, Demedts, M, Nemery, B
A previously healthy student developed the organic dust toxic syndrome after unloading a grain silo for one day. Bronchoalveolar lavage seven days later showed a total cell count six times normal...
Clottens, F L, Verbeken, E K, Demedts, M, Nemery, B
OBJECTIVES: It was hypothesised from an epidemiological investigation that a formula change from Acramin FWR (a polyurea) to Acramin FWN (a polyamide-amine) had led to severe pulmonary disease in...
Spruit, M, Thomeer, M, Gosselink, R, Troosters, T, Kasran, A, Debrock, A, ...
Background: Skeletal muscle weakness is assumed to be present in patients with sarcoidosis but has never been reported in a consecutive group of patients. Moreover, its relationship with previously...
Van Klaveren, R. J., Roelant, C., Boogaerts, M., Demedts, M., Nemery, B.
BACKGROUND: Although alveolar macrophages are considered to be the primary cellular mediators of host defence in the lung, there is increasing evidence that type II cells may also play an active role...
Putrescine accumulation in human pulmonary tumours.
Hoet, P. H., Dinsdale, D., Verbeken, E. K., Demedts, M., Nemery, B.
Type II pneumocytes and Clara cells, both epithelial cells that possess an active uptake system for polyamines, have been identified as possible precursor cells of at least some types of lung...