Rudwaleit, M, Landewe, Rene, Listing, J, Brandt, J, Braun, J, ...
Objective: Non-radiographic axial spondyloarthritis (SpA) is characterised by a lack of definitive radiographic sacroiliitis and is considered an early stage of ankylosing spondylitis. The objective...
Rudwaleit, M, Landewe, R, Listing, J, Akkoc, N, Brandt, J, ...
Objective: To validate and refine two sets of candidate criteria for the classification/diagnosis of axial spondyloarthritis (SpA). Methods: All assessment of SpondyloArthritis international Society...
Sieper, J, Landewe, R, Brandt, J, Burgos-Vagas, R, Collantes-Estevez, E, ...
Objective: Inflammatory back pain (IBP) is an important clinical symptom in patients with axial spondyloarthritis (SpA), and relevant for classification and diagnosis. In the present report, a new...
Landewe, R, Dougados, M, Mielants, Herman
Aim: To study the relationship between disease activity, radiographic damage and physical function in patients with ankylosing spondylitis (AS) Patients and methods: Baseline and 2-year data of the...
Visser, K, Katchamart, W, Loza, E, Martinez-Lopez, JA, Salliot, C, Trudeau, J, ...
Objectives: To develop evidence-based recommendations for the use of methotrexate in daily clinical practice in rheumatic disorders. Methods: 751 rheumatologists from 17 countries participated in the...
Visser, K, Katchamart, W, Loza, E, Martinez-Lopez, JA, Salliot, C, Trudeau, J, ...
Objectives: To develop evidence-based recommendationsfor the use of methotrexate in daily clinical practicein rheumatic disorders.Methods: 751 rheumatologists from 17 countriesparticipated in the 3E...
Visser, K, Katchamart, W, Loza, E, Martinez-Lopez, JA, Salliot, C, Trudeau, J, ...
Objectives: To develop evidence-based recommendations for the use of methotrexate (MTX) in daily clinical practice in rheumatic disorders. Methods: A total of 751 rheumatologists from 17 countries...
Zhang, W., Moskowitz, R.W., Nuki, G., Abramson, S., Altman, R.P., Arden, N., ...
PURPOSE: To develop concise, patient-focussed, up to date, evidence-based, expert consensus recommendations for the management of hip and knee osteoarthritis (OA), which are adaptable and designed to...
Zhang, W., Moskowitz, R.W., Nuki, G., Abramson, S., Altman, R.D., Arden, N., ...
PURPOSE: To develop concise, patient-focussed, up to date, evidence-based, expert consensus recommendations for the management of hip and knee osteoarthritis (OA), which are adaptable and designed to...
Visser, K, Katchamart, W, Loza, E, Martinez-Lopez, JA, Salliot, C, Trudeau, J, ...
Objectives: To develop evidence-based recommendations for the use of methotrexate (MTX) in daily clinical practice in rheumatic disorders. Methods: A total of 751 rheumatologists from 17 countries...
Gossec, L., Dougados, M., Phillips, C., Hammoudeh, M., De Vlam, K., Pavelka, K., ...
Background: Ten ASAS/EULAR recommendations for the management of ankylosing spondylitis (AS) were published in 2006. Objectives: (a) To disseminate and (b) to evaluate conceptual agreement with, and...
Visser, K, Katchamart, W, Loza, E, Martinez-Lopez, JA, Salliot, C, Trudeau, J, ...
Objectives: To develop evidence-based recommendations for the use of methotrexate (MTX) in daily clinical practice in rheumatic disorders. Methods: A total of 751 rheumatologists from 17 countries...
Sidiropoulos, P. I., Hatemi, G., Avouac, J., Collantes, E., Hamuryudan, V., ...
Objective. Recommendations and/or guidelines represent a popular way of integrating evidence-based medicine into clinical practice. The 3E Initiatives is a multi-national effort to develop...
Zhang, W., Moskowitz, R.W., Nuki, G., Abramson, S., Altman, R.D., Arden, N., ...
PURPOSE: As a prelude to developing updated, evidence-based, international consensus recommendations for the management of hip and knee osteoarthritis (OA), the Osteoarthritis Research Society...
Salliot, C., Gossec, L., Ruyssen-Witrand, A., Luc, M., Duclos, M., Guignard, S., ...
Objective. To evaluate the rate of infections in rheumatic patients treated with tumour necrosis factor (TNF)-α blockers in daily practice and to determine potential risk factors of infections....
Determinants of hyperkyphosis in patients with ankylosing spondylitis. (2006)
Vosse, D., Landewé, R., Mielants, H., Dougados, M., ...
Objective: To determine clinical and radiographic determinants of hyperkyphosis in patients with ankylosing spondylitis.Methods: Spinal hyperkyphosis was assessed by occiput to wall distance (OWD) in...
Determinants of hyperkyphosis in patients with ankylosing spondylitis. (2006)
Vosse, D., Landewé, R., Mielants, H., Dougados, M., ...
Objective: To determine clinical and radiographic determinants of hyperkyphosis in patients with ankylosing spondylitis.Methods: Spinal hyperkyphosis was assessed by occiput to wall distance (OWD) in...
Determinants of hyperkyphosis in patients with ankylosing spondylitis. (2006)
Vosse, D., Landewé, R., GEUSENS, Piet, Mielants, H., Dougados, M., ...
Objective: To determine clinical and radiographic determinants of hyperkyphosis in patients with ankylosing spondylitis.Methods: Spinal hyperkyphosis was assessed by occiput to wall distance (OWD) in...
ASAS/EULAR recommendations for the management of ankylosibg spondylitiis (2006)
Zochling, J, Burgos-Vargas, R, Collantes, E, Davis, JC, Dijkmans, B, ...
PHAM, T, LANDEWE, R, DOUGADOS, M, SIEPER, J, BRAUN, J, ...
Determinants of hyperkyphosis in patients with ankylosing spondylitis (2006)
VOSSE, D, LANDEWE, R, GEUSENS, P, Mielants, Herman, DOUGADOS, M, ...
ASAS/EULAR recommendations for the management of ankylosing spondylitis. (2006)
Zochling, J, Burgos Vargas, R, Collantes, E, Davis, J C, Dijkmans, B, ...
OBJECTIVE: To develop evidence based recommendations for the management of ankylosing spondylitis (AS) as a combined effort of the 'ASsessment in AS' international working group and the European...
Pham, T., Landewe, R., Dougados, M., Sieper, J., Braun, J., ...
Objectives: To determine the type and proportion of patients with ankylosing spondylitis who rheumatologists consider to be candidates for treatment with tumour necrosis factor (TNF)-blocking agents,...
Continuation of treatment with infliximab in ankylosing spondylitis: 2-yr open follow-up (2006)
Gossec, L., Le Henanff, A., Breban, M., Vignon, E., Claudepierre, P., Devauchelle, V., ...
Objective. To evaluate the continuation and safety of treatment with infliximab in ankylosing spondylitis (AS) over a 2-yr period. Methods. This study was an open, observational, 2-yr extension study...
Continuation of treatment with infliximab in ankylosing spondylitis: 2-yr open follow-up (2006)
Gossec, L., Henanff, A. Le, Breban, M., Vignon, E., Claudepierre, P., Devauchelle, V., ...
Objective. To evaluate the continuation and safety of treatment with infliximab in ankylosing spondylitis (AS) over a 2-yr period. Methods. This study was an open, observational, 2-yr extension study...
Salliot, C., Gossec, L., Ruyssen-Witrand, A., Luc, M., Duclos, M., Guignard, S., ...
Objective. To evaluate the rate of infections in rheumatic patients treated with tumour necrosis factor (TNF)-α blockers in daily practice and to determine potential risk factors of infections....
Continuation of treatment with infliximab in ankylosing spondylitis: 2-yr open follow-up (2006)
Gossec, L., Henanff, A. Le, Breban, M., Vignon, E., Claudepierre, P., Devauchelle, V., ...
Objective. To evaluate the continuation and safety of treatment with infliximab in ankylosing spondylitis (AS) over a 2-yr period. Methods. This study was an open, observational, 2-yr extension study...
Salliot, C., Gossec, L., Ruyssen-Witrand, A., Luc, M., Duclos, M., Guignard, S., ...
Objective. To evaluate the rate of infections in rheumatic patients treated with tumour necrosis factor (TNF)-α blockers in daily practice and to determine potential risk factors of infections....
Zhang, W., Doherty, M., Arden, N., Bannwarth, B., Bijlsma, J., ...
Objective: To develop evidence based recommendations for the management of hip osteoarthritis (OA). Methods: The multidisciplinary guideline development group comprised 18 rheumatologists, 4...
Spoorenberg, A, Van Tubergen, A, Landewe, R, Dougados, M, Mielants, H, ...
Objective. There is no 'gold standard' to assess disease activity in patients with ankylosing spondylitis (AS). It is known that patients and physicians have different opinions about disease...
Minimal disease activity for rheumatoid arthritis: A preliminary definition (2005)
Wells, G. A., Boers, M., Shea, B., Brooks, P. M., Simon, L. S., Strand, C. V., ...
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of...
Spoorenberg, A, Van Tubergen, A, Landewe, R, Dougados, M, Mielants, H, ...
Objective. There is no 'gold standard' to assess disease activity in patients with ankylosing spondylitis (AS). It is known that patients and physicians have different opinions about disease...
Minimal disease activity for rheumatoid arthritis: A preliminary definition (2005)
Wells, G. A., Boers, M., Shea, B., Brooks, P. M., Simon, L. S., Strand, C. V., ...
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of...
Minimal disease activity for rheumatoid arthritis: A preliminary definition (2005)
Wells, G. A., Boers, M., Shea, B., Brooks, P. M., Simon, L. S., Strand, C. V., ...
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of...
Tubach, F, Baron, G, Falissard, B, Logeart, I, Dougados, M, Bellamy, N, ...
Background: The WOMAC ( Western Ontario and McMaster Universities) function subscale is widely used in clinical trials of hip and knee osteoarthritis. Reducing the number of items of the subscale...
Tubach, F, Ravaud, P, Baron, G, Falissard, B, Logeart, I, Bellamy, N, ...
Background: In clinical trials, at the group level, results are usually reported as mean and standard deviation of the change in score, which is not meaningful for most readers. Objective: To...
Tubach, F, Ravaud, P, Baron, G, Falissard, B, Logeart, I, Bellamy, N, ...
Background: The patient acceptable symptom state ( PASS) is the value beyond which patients can consider themselves well. This concept can help in interpreting results of clinical trials. Objective:...
ZHANG, W, DOHERTY, M, ARDEN, N, BANNWARTH, B, BIJLSMA, J, GUNTHER, KP, ...
Parameters contributing to inflammatory back pain (IBP) according to experts (2005)
RUDWALEIT, M, LANDEWE, R, BRANDT, J, BURGOS-VARGAS, R, COLLANTES-ESTEVEZ, E, DIJKMANS, B, ...
Tubach, F, Baron, G, Falissard, B, Logeart, I, Dougados, M, Bellamy, N, ...
Background: The WOMAC ( Western Ontario and McMaster Universities) function subscale is widely used in clinical trials of hip and knee osteoarthritis. Reducing the number of items of the subscale...
Tubach, F, Ravaud, P, Baron, G, Falissard, B, Logeart, I, Bellamy, N, ...
Background: In clinical trials, at the group level, results are usually reported as mean and standard deviation of the change in score, which is not meaningful for most readers. Objective: To...
Tubach, F, Ravaud, P, Baron, G, Falissard, B, Logeart, I, Bellamy, N, ...
Background: The patient acceptable symptom state ( PASS) is the value beyond which patients can consider themselves well. This concept can help in interpreting results of clinical trials. Objective:...
Minimal disease activity for rheumatoid arthritis: A preliminary definition (2005)
Wells, G. A., Boers, M., Shea, B., Brooks, P. M., Simon, L. S., Strand, C. V., ...
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of...
Minimal disease activity for rheumatoid arthritis: a preliminary definition (2005)
Wells, G. A., Boers, M., Shea, B., Brooks, P. M., Simon, L. S., Strand, C. V., ...
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of...
Spoorenberg, A., Van Tubergen, A., Landewé, R., Dougados, M., Mielants, H., ...
Objective. There is no ‘gold standard’ to assess disease activity in patients with ankylosing spondylitis (AS). It is known that patients and physicians have different opinions about disease...
Spoorenberg, A., Van Tubergen, A., Landewé, R., Dougados, M., Mielants, H., ...
Objective. There is no ‘gold standard’ to assess disease activity in patients with ankylosing spondylitis (AS). It is known that patients and physicians have different opinions about disease...
Furst, Daniel E, Breedveld, F C, Kalden, J R, Smolen, J S, Burmester, G R, Bijlsma, JWJ, ...
As in previous years, the consensus group to consider the use of biological agents was constituted by rheumatologists from the Universities of Erlangen, Leiden, and Vienna in Europe in cooperation...
Clusterin, a potential pathophysiological actor in rheumatoid arthritis (2004)
Devauchelle, V, Breban, M, Dougados, M, Fournier, C, Chiocchia, G
No abstract available.
De Vlam, K, Dougados, M, Mielants, H, De Tempel, HV, VAN DER HEIJDE, Desiree, ...
Objective. To compare reliability and change over time of radiological scoring methods in ankylosing spondylitis (AS). Methods. Two trained observers scored 217 sets of radiographs from baseline and...
Spoorenberg, B, De Vlam, K, Dougados, M, Mielants, H, De Tempel, HV, ...
Objective. To compare reliability and change over time of radiological scoring methods in ankylosing spondylitis (AS). Methods. Two trained observers scored 217 sets of radiographs from baseline and...
Pham, T, Altman, RD, Anderson, JJ, Bellamy, N, Hochberg, M, ...
Background: The OARSI Standing Committee for Clinical Trials Response Criteria Initiative had developed two sets of responder criteria to present the results of changes after treatment in three...
What is the most appropriate radiologic scoring method for ankylosing spondylitis? (2004)
WANDERS, AJB, LANDEWE, RBM, SPOORENBERG, A, DOUGADOS, M, Mielants, Herman, ...
HEUFT-DORENBOSCH, L, VAN TUBERGEN, A, SPOORENBERG, A, LANDEWE, R, DOUGADOS, M, Mielants, Herman, ...
Pham, T, Altman, RD, Anderson, JJ, Bellamy, N, Hochberg, M, ...
Background: The OARSI Standing Committee for Clinical Trials Response Criteria Initiative had developed two sets of responder criteria to present the results of changes after treatment in three...
ISSAS: International Start TNF-blocker Study in Ankylosing Spondylitis (2004)
Pham, T, Landewe, R, Dougados, M, Burgos-Vargas, R, Collantes-Estevez, E, Edmonds, J, ...
Jordan, K.M., Arden, N.K., Doherty, M., Bannwarth, B., Bijlsma, J.W., Dieppe, P., ...
Objectives: To update the EULAR recommendations for management of knee osteoarthritis (OA) by an evidence based medicine and expert opinion approach. Methods: The literature search and guidelines...
Van Tubergen, A, Anderson, J, Landewe, R, Dougados, M, Braun, J, Bellamy, N, ...
Objective: To investigate whether the recently developed (statistically derived) "ASsessment in Ankylosing Spondylitis Working Group" improvement criteria (ASAS-IC) for ankylosing spondylitis (AS)...
Van Tubergen, A, Anderson, J, Landewe, R, Dougados, M, Braun, J, Bellamy, N, ...
Objective: To investigate whether the recently developed (statistically derived) "ASsessment in Ankylosing Spondylitis Working Group" improvement criteria (ASAS-IC) for ankylosing spondylitis (AS)...
Pham, T, Calin, A, Khan, MA, Bellamy, N, ...
Background: There is ample evidence of important symptomatic efficacy of tumour necrosis factor alpha (TNFalpha) inhibition in ankylosing spondylitis (AS). Moreover, studies suggest that anti-TNF...
Pham, T., Lassere, M., Altman, R. D., Andersen, J., Bellamy, N., ...
Improvement in analysis and reporting results of osteoarthritis (OA) clinical trials has been recently obtained because of harmonization and standardization of the selection of outcome variables...
Van Tubergen, A., Anderson, J., Landewe, R., Dougados, M., Braun, J., ...
Objective: To investigate whether the recently developed (statistically derived) "ASsessment in Ankylosing Spondylitis Working Group" improvement criteria (ASAS-IC) for ankylosing spondylitis (AS)...
Pham, T, Lassere, M, Altman, RD, Anderson, JJ, Bellamy, N, ...
Improvement in analysis and reporting results of osteoarthritis (OA) clinical trials has been recently obtained because of harmonization and standardization of the selection of outcome variables...
BOONEN, A, LANDEWE, R, GUILLEMIN, F, DOUGADOS, M, ...
Costs of ankylosing spondylitis in three European countries: the patient's perspective (2003)
BOONEN, A, LANDEWE, R, GUILLEMIN, F, SPOORENBERG, A, SCHOUTEN, H, ...
Assessment of enthesitis in ankylosing spondylitis (2003)
HEUSCH-DORENBOSCH, L, SPOORENBERG, A, VAN TUBERGEN, A, LANDEWE, R, Mielants, Herman, ...
Pham, T, Calin, A, Khan, MA, Bellamy, N, ...
Background: There is ample evidence of important symptomatic efficacy of tumour necrosis factor alpha (TNFalpha) inhibition in ankylosing spondylitis (AS). Moreover, studies suggest that anti-TNF...
Pham, T., Lassere, M., Altman, R. D., Andersen, J., Bellamy, N., ...
Improvement in analysis and reporting results of osteoarthritis (OA) clinical trials has been recently obtained because of harmonization and standardization of the selection of outcome variables...
Van Tubergen, A., Anderson, J., Landewe, R., Dougados, M., Braun, J., ...
Objective: To investigate whether the recently developed (statistically derived) "ASsessment in Ankylosing Spondylitis Working Group" improvement criteria (ASAS-IC) for ankylosing spondylitis (AS)...
Assessment of fatigue in the management of patients with ankylosing spondylitis (2003)
Dernis-Labous, E., Messow, M., Dougados, M.
Background. Pain, stiffness, functional impairment, range of motion and quality of life are the main conventional domains used in studies evaluating ankylosing spondylitis (AS). However, fatigue has...
Assessment of fatigue in the management of patients with ankylosing spondylitis (2003)
Dernis-Labous, E., Messow, M., Dougados, M.
Background. Pain, stiffness, functional impairment, range of motion and quality of life are the main conventional domains used in studies evaluating ankylosing spondylitis (AS). However, fatigue has...
Assessment of fatigue in the management of patients with ankylosing spondylitis (2003)
Dernis-Labous, E., Messow, M., Dougados, M.
Background. Pain, stiffness, functional impairment, range of motion and quality of life are the main conventional domains used in studies evaluating ankylosing spondylitis (AS). However, fatigue has...
Reliability of self assessed joint counts in ankylosing spondylitis (2002)
Spoorenberg, A, Dougados, M, De Vlam, K, Mielants, H, ...
Objective: To determine the reliability of self reported joint counts to assess pain or swelling in ankylosing spondylitis (AS). Methods: 2 17 outpatients fulfilling the modified New York criteria...
Reliability of self assessed joint counts in ankylosing spondylitis (2002)
Spoorenberg, A, Dougados, M, De Vlam, K, Mielants, H, ...
Objective: To determine the reliability of self reported joint counts to assess pain or swelling in ankylosing spondylitis (AS). Methods: 2 17 outpatients fulfilling the modified New York criteria...
Van Tubergen, A., Andersen, J., Landewe, R., Dougados, M., Bellamy, N., ...
Objective: To investigate whether the recently developed (statistically derived) "ASsessment in Ankylosing Spondylitis Working Group" improvement criteria (ASAS-IC) for ankylosing spondylitis (AS)...
Pham, T., Altman, R., Bellamy, N., Hochberg, M., Simon, L., ...
BOONEN, A, LANDEWE, R, SPOORENBERG, A, SCHOUTEN, H, ...
Reliability of self assessed joint counts in ankylosing spondylitis. (2002)
SPOORENBERG, A, DOUGADOS, M, De Vlam, Kurt, Mielants, Herman, ...
Van Tubergen, A., Andersen, J., Landewe, R., Dougados, M., Bellamy, N., ...
Objective: To investigate whether the recently developed (statistically derived) "ASsessment in Ankylosing Spondylitis Working Group" improvement criteria (ASAS-IC) for ankylosing spondylitis (AS)...
Pham, T., Altman, R., Bellamy, N., Hochberg, M., Simon, L., ...
Rapid diagnosis of inflammatory synovial fluid with reagent strips (2002)
Ravaud, P., Hudry, C., Giraudeau, B., Weill, B., Dougados, M.
Objective. To determine the usefulness of reagent test strips for screening inflammatory synovial fluid (SF). Methods. Consecutive patients undergoing diagnostic arthrocentesis,...
Breban, M., Vignon, E., Claudepierre, P., Devauchelle, V., Wendling, D., Lespessailles, E., ...
Objective. To evaluate the efficacy and safety of a loading regimen of the anti‐tumour necrosis factor α (TNF‐α) antibody infliximab in predominantly axial severe ankylosing...
Maillefert, J. F., Gueguen, A., Nguyen, M., Berdah, L., Lequesne, M., Mazières, B., ...
Objective. To determine a cut‐off point above which a change in joint space width (JSW) could be considered as relevant in patients with hip osteoarthritis (OA) on the...
Maillefert, J. F., Nguyen, M., Gueguen, A., Berdah, L., Lequesne, M., Mazières, B., ...
Aim. To determine the minimum clinically important difference (MCID) in joint space width (JSW) progression in patients with hip osteoarthritis (OA), based upon...
Towards a definition of "difference" in osteoarthritis (2001)
Bellamy, N, Carr, A, Dougados, M, Shea, B, Wells, G
To assess existing information regarding detectable differences in osteoarthritis (OA), a systematic literature search was conducted up to December 1999. Thirty-three articles were considered...
Towards a definition of "difference" in osteoarthritis (2001)
Bellamy, N, Carr, A, Dougados, M, Shea, B, Wells, G
To assess existing information regarding detectable differences in osteoarthritis (OA), a systematic literature search was conducted up to December 1999. Thirty-three articles were considered...
Duche, A., Dougados, M., Ravaud, P.
Objectives. We assessed the influence of patient positioning and radiographic procedure, and defined a smallest detectable difference (SDD) in hip osteoarthritis (OA)....
Dougados, M, LeClaire, P, Bloch, DA, Bellamy, N, Altman, RD, VAN DER HEIJDE, Desiree
Background: The domains of pain, function and patient's global assessment are identified as core variables and frequently measured in clinical trials of patients with osteoarthritis (OA) of the hip...
Dougados, M, LeClaire, P, Bloch, DA, Bellamy, N, Altman, RD, VAN DER HEIJDE, Desiree
Background: The domains of pain, function and patient's global assessment are identified as core variables and frequently measured in clinical trials of patients with osteoarthritis (OA) of the hip...
Clinical relevance of C-reactive protein in axial involvement of ankylosing spondylitis. (1999)
DOUGADOS, M, GUEGUEN, A, NAKACHE, JP, VELICITAT, P, ZEIDLER, H, Veys, Eric, ...
Calin, A., Gueguen, A., Zeidler, H., Mielants, H., Dougados, M.
Objective. Disease activity has been defined using a self-administered instrument, focusing on fatigue, axial pain, peripheral pain, enthesopathy and morning stiffness [Bath Ankylosing Spondylitis...
Brooks, P., Emery, P., Evans, J. F., Fenner, H., Hawkey, C. J., Patrono, C., ...
The International Consensus Meeting on the Mode of Action of COX-2 Inhibition (ICMMAC) brought together 17 international experts in arthritis, gastroenterology and pharmacology on 5–6 December...
Dougados, M, Gueguen, A, Nakache, JP, Velicitat, P, Veys, EM, Zeidler, H, ...
Objective. To consider the re3levance of the duration of a clinical trial in ankylosing spondylitis: long-term (i.e. 1 yr) vs short-term (i.e. 6 weeks) assessment of a non-steroidal anti-inflammatory...
Recommendations for the registration of drugs used in the treatment of osteoarthritis. (1996)
DOUGADOS, M, DEVOGELAER, JP, ANNEFELDT, M, AVOUAC, B, BOUVENOT, G, COOPER, C, ...
RAVAUD, P., CHASTANG, C., ROUSSELIN, B., PAOLOZZI, L., AMOR, B., ...
We studied the influence of the radiographic procedure and joint positioning on knee joint space width (JSW) in 10 healthy volunteers, and the intrareader reproducibility of JSW measurements on...
PREDICTIVE FACTORS OF SEVERITY OF SPONDYLOARTHROPATHY IN NORTH AFRICA (1995)
CLAUDEPIERRE, P., GUEGUEN, A., LADJOUZE, A., HAJJAJ-HASSOUNI, N., SELLAMI, S., AMOR, B., ...
Both genetic and environmental factors probably influence the severity of spondyloarthropathies. Hip involvement, which may be used as a marker of disease severity, is more frequent in...
Sulphasalazine in ankylosing spondylitis: a double blind controlled study in 60 patients.
Dougados, M, Boumier, P, Amor, B
Sulphasalazine has been reported to be effective in ankylosing spondylitis with peripheral arthritis, but its efficacy in spondylitis is unknown. Thus 60 patients with active ankylosing spondylitis...
Sulphasalazine in ankylosing spondylitis: a double blind controlled study in 60 patients.
Dougados, M, Boumier, P, Amor, B
Sulphasalazine has been reported to be effective in ankylosing spondylitis with peripheral arthritis, but its efficacy in spondylitis is unknown. Thus 60 patients with active ankylosing spondylitis...
Nonathymulin in rheumatoid arthritis: two double blind, placebo controlled trials.
Amor, B, Dougados, M, Mery, C, Dardenne, M, Bach, J F
Two randomised double blind, placebo controlled trials have been carried out to assess the effectiveness of nonathymulin, a synthetic thymic peptide hormone, in the treatment of rheumatoid arthritis...
Cyclosporin in rheumatoid arthritis: a double blind, placebo controlled study in 52 patients.
Dougados, M, Awada, H, Amor, B
The efficacy and safety of cyclosporin A (CyA) for patients with rheumatoid arthritis were assessed in a four month double blind, placebo controlled study using an initial dosage of 5 mg/kg daily....
Dougados, M, Duchesne, L, Awada, H, Amor, B
The efficacy of cyclosporin in a double blind, placebo controlled trial of four months' duration has previously been reported by us. To assess the benefit-to-risk of cyclosporin this study was...
Evaluation of sulphasalazine in the treatment of spondyloarthropathies.
Dougados, M, Maetzel, A, Mijiyawa, M, Amor, B
Sulphasalazine has been shown to have an effect in patients with spondyloarthropathies, but the clinical indication for its use is controversial and its long term effect has not yet been evaluated....
Crilly, A, Kolta, S, Dougados, M, Sturrock, R D, Amor, B, Capell, H A, ...
OBJECTIVE--To investigate the effect of cyclosporin A (CyA) therapy on circulating concentrations of interleukin-6 (IL-6) and soluble interleukin-2 receptor (sIL-2R) in patients with rheumatoid...
Dougados, M, Gueguen, A, Nguyen, M, Berdah, L, Lequesne, M, Mazieres, B, ...
OBJECTIVES: To determine a cut off value for changes in radiological joint space width that allowed definition of radiological progression of hip osteoarthritis not related to measurement method...
Ravaud, P., Giraudeau, B., Auleley, G., Drape, J., Rousselin, B., Paolozzi, L., ...
OBJECTIVES—(1) To assess reproducibility of medial knee joint space width (JSW) measurement in healthy subjects and osteoarthritic (OA) patients. (2) To define minimal relevant radiological change...
Auleley, G., Rousselin, B., Ayral, X., Edouard-Noel, R., Dougados, M., Ravaud, P.
OBJECTIVE—To assess the effect of standing position on joint space width (JSW) measurements of the hips with and without osteoarthritis (OA) on pelvic radiographs. METHODS—Adult patients aged...
Are radiological joint space widths of normal hips asymmetrical?
Reis, P., Nahal-Said, R., Ravaud, P., Dougados, M., Amor, B.
BACKGROUND—To be certain that the joint space width is abnormal in the case of hip joint pain when compared with the contralateral hip requires knowledge of physiological dissymmetry. AIM OF THE...
Dougados, M., Combe, B., Cantagrel, A., Goupille, P., Olive, P., Schattenkirchner, M., ...
OBJECTIVES—To investigate the potential clinical benefit of a combination therapy. METHODS—205 patients fulfilling the ACR criteria for rheumatoid arthritis (RA), not treated with disease...
Pendleton, A, Arden, N, Dougados, M, Doherty, M, Bannwarth, B, Bijlsma, J, ...
BACKGROUND—Osteoarthritis (OA) is the most common joint disease encountered throughout Europe. A task force for the EULAR Standing Committee for Clinical Trials met in 1998 to determine the...
Auleley, G., Giraudeau, B., Dougados, M., Ravaud, P.
OBJECTIVE—To compare radiographic reading procedures and evaluate their impact on sample size in hip osteoarthritis (OA) longitudinal studies. METHODS—Pelvic radiographs performed twice, three...
Said-Nahal, R, Miceli-Richard, C, Gautreau, C, Tamouza, R, Borot, N, Porcher, R, ...
Objectives: To investigate whether HLA alleles, other than HLA-B27, influence predisposition to spondyloarthropathy (SpA) in multiplex families.
Emery, P, Breedveld, F, Dougados, M, Kalden, J, Schiff, M, Smolen, J
Objective: To develop a referral recommendation that may serve as a clinical guide for primary care doctors, enabling them to identify patients with suspected RA during the early inflammatory stages.
Boonen, A, Landewe, R, Spoorenberg, A, Schouten, H, Rutten-Van, M, ...
Objective: To compare work disability, sick leave, and productivity costs due to ankylosing spondylitis (AS) of three European countries.
Prevalence of hepatitis C virus infection in patients with rheumatoid arthritis
Maillefert, J, Muller, G, Falgarone, G, Bour, J, Ratovohery, D, Dougados, M, ...
Objective: To evaluate the prevalence of HCV infection in patients with RA.
Reliability of self assessed joint counts in ankylosing spondylitis
Spoorenberg, A, Dougados, M, De Vlam, K, Mielants, H, ...
Objective: To determine the reliability of self reported joint counts to assess pain or swelling in ankylosing spondylitis (AS).
Sex differences in hip osteoarthritis: results of a longitudinal study in 508 patients
Maillefert, J, Gueguen, A, Monreal, M, Nguyen, M, Berdah, L, Lequesne, M, ...
Objective: To evaluate sex differences in the clinical and structural presentation, and natural history of hip OA.
Jordan, K, Arden, N, Doherty, M, Bannwarth, B, Bijlsma, J, Dieppe, P, ...
Objectives: To update the EULAR recommendations for management of knee osteoarthritis (OA) by an evidence based medicine and expert opinion approach.
Meyer, O, Labarre, C, Dougados, M, Goupille, P., Cantagrel, A, Dubois, A, ...
Objective: To study the value of antibodies to citrullinated proteins/peptides for predicting joint outcomes in patients with recent onset rheumatoid arthritis (RA).
Assessment of enthesitis in ankylosing spondylitis
Heuft-Dorenbosch, L, Spoorenberg, A, Van Tubergen, A, Landewe, R, Mielants, H, ...
Objective: To assess, firstly, the validity of the enthesis index published by Mander (Mander enthesis index (MEI)) and, secondly, to investigate whether it is possible to define a new enthesis index...
Van Tubergen, A, Anderson, J, Landewe, R, Dougados, M, Braun, J, ...
Objective: To investigate whether the recently developed (statistically derived) "ASsessment in Ankylosing Spondylitis Working Group" improvement criteria (ASAS-IC) for ankylosing spondylitis (AS)...
Allali, F, Breban, M, Porcher, R, Maillefert, J, Dougados, M, Roux, C
Patients and methods: 29 patients (six women; 23 men) aged 22–68 years, with persistently active SpA despite a high dose of non-steroidal anti-inflammatory drug and/or treatment with methotrexate...
Maillefert, J, Combe, B, Goupille, P, Cantagrel, A, Dougados, M
Methods: Study design: five year multicentre prospective longitudinal trial. Participants: 146/205 patients with RA previously included in a one year prospective randomised trial comparing the...
Boonen, A, Landewe, R, Guillemin, F, Rutten-van, M, Dougados, M, ...
Objective: To assess direct costs associated with ankylosing spondylitis (AS). To determine which variables, including country, predict costs.
Costs of ankylosing spondylitis in three European countries: the patient's perspective
Boonen, A, Landewe, R, Guillemin, F, Spoorenberg, A, Schouten, H, ...
Objective: To assess a patient's out of pocket costs, income loss, time consumption, and quality of life (QoL) due to ankylosing spondylitis (AS) in three European countries and to assess variables...
Disability in adults with hip and knee arthroplasty: a French national community based survey
Boutron, I, Poiraudeau, S, Ravaud, J, Baron, G, Revel, M, Nizard, R, ...
Objectives: To compare levels of disability of people with and without hip and knee arthroplasty in a random national sample.
Pham, T, Calin, A, Khan, M, Bellamy, N, ...
Background: There is ample evidence of important symptomatic efficacy of tumour necrosis factor α (TNFα) inhibition in ankylosing spondylitis (AS). Moreover, studies suggest that anti-TNF could be...
Braun, J, Pham, T, Sieper, J, Davis, J, Dougados, M, ...
Objective: To obtain an international consensus about the use of anti-tumour necrosis factor α (anti-TNFα) for treating patients with ankylosing spondylitis (AS).
Conventional treatments for ankylosing spondylitis
Dougados, M, Dijkmans, B, Khan, M, Maksymowych, W, Brandt, J
Management of ankylosing spondylitis (AS) is challenged by the progressive nature of the disease. To date, no intervention is available that alters the underlying mechanism of inflammation in AS....
Staging of patients with ankylosing spondylitis: a preliminary proposal
Braun, J, Dougados, M, Emery, P, Khan, M, Sieper, J, ...
Patients with ankylosing spondylitis (AS) are characterised by a wide range of clinical presentations, radiographic profiles, and outcomes, which are not well differentiated by current diagnostic and...
Atkins, C, Malaise, M, Sany, J, Russell, A, ...
Objective: To evaluate the efficacy and safety of monotherapy with adalimumab in patients with RA for whom previous DMARD treatment has failed.
Prognostic factors for remission in early rheumatoid arthritis: a multiparameter prospective study
Gossec, L, Dougados, M, Goupille, P, Cantagrel, A, Sibilia, J, Meyer, O, ...
Objective: To determine prognostic factors for remission in early rheumatoid arthritis.
Ravaud, P, Giraudeau, B, Logeart, I, Larguier, J, Rolland, D, Treves, R, ...
Background: Diary recording of pain and disabling activities in osteoarthritis (OA) is widely recommended, but, to our knowledge, its impact on symptoms has not been investigated. Exercise programmes...
Mach, P S, Kharouby, M, Lutcher, F, Olivier, J L, Bazely, N, Dougados, M, ...
The in vitro production of anti-double stranded DNA antibodies (anti-DNA) by peripheral blood mononuclear cells (PBMC) was investigated in 19 patients with systemic lupus erythematosus (SLE) and in...
Mach, P S, Kharouby, M, Lutcher, F, Olivier, J L, Bazely, N, Dougados, M, ...
Peripheral blood mononuclear cells (PBMC) of 29 patients with systemic lupus erythematosus (SLE) and 14 normal individuals were investigated for the in vitro production of anti-nuclear antibodies...
Lopez, S, Halbwachs-Mecarelli, L, Ravaud, P, Bessou, G, Dougados, M, Porteu, F
In vitro analysis of polymorphonuclear neutrophils (PMN) has allowed various stages of cell activation to be distinguished, characterized by the expression level of specific membrane markers and of...
Paracetamol in osteoarthritis of the knee
Miceli-Richard, C, Le Bars, M, Schmidely, N, Dougados, M
Background: Paracetamol is a recommended symptomatic treatment of osteoarthritis (OA), but in clinical trials sample sizes have been relatively small and variable daily doses of paracetamol have been...
Detection of small joint synovitis by ultrasonography: the learning curve of rheumatologists
D'Agostino, M, Maillefert, J, Said-Nahal, R, Breban, M, Ravaud, P, Dougados, M
Background: Ultrasonography allows assessment of soft tissue structures and has become a valued tool for diagnosing synovitis.
Furst, D, Breedveld, F, Kalden, J, Smolen, J, Burmester, G, Bijlsma, J, ...
Wanders, A, Landewe, R, Spoorenberg, A, De Vlam, K, Mielants, H, Dougados, M, ...
Objectives: To describe the influence of the reading order (chronological v paired) on radiographic scoring results in ankylosing spondylitis. To investigate whether this method is sufficiently...
Pham, T, Le Henanff, A, Ravaud, P., Dieppe, P, Paolozzi, L, Dougados, M
Objective: To evaluate long term efficacy of three iterative courses of three weekly intra-articular (IA) injections of NRD101 in the treatment of symptomatic knee osteoarthritis (OA).
Tubach, F, Ravaud, P, Baron, G, Falissard, B, Logeart, I, Bellamy, N, ...
Background: The patient acceptable symptom state (PASS) is the value beyond which patients can consider themselves well. This concept can help in interpreting results of clinical trials.
Using patients' and rheumatologists' opinions to specify a short form of the WOMAC function subscale
Tubach, F, Baron, G, Falissard, B, Logeart, I, Dougados, M, Bellamy, N, ...
Background: The WOMAC (Western Ontario and McMaster Universities) function subscale is widely used in clinical trials of hip and knee osteoarthritis. Reducing the number of items of the subscale...
Dougados, M, Emery, P, Lemmel, E, Zerbini, C, Brin, S, Van Riel, P
Objective: To evaluate the efficacy and safety of adding sulfasalazine to leflunomide treatment compared with switching to sulfasalazine alone in patients with RA with an inadequate response to...
Tubach, F, Ravaud, P, Baron, G, Falissard, B, Logeart, I, Bellamy, N, ...
Background: In clinical trials, at the group level, results are usually reported as mean and standard deviation of the change in score, which is not meaningful for most readers.
Braun, J, Landewe, R, Davis, J, Sieper, J, ...
Zhang, W, Doherty, M, Arden, N, Bannwarth, B, Bijlsma, J, Gunther, K, ...
Objective: To develop evidence based recommendations for the management of hip osteoarthritis (OA).
Tolerance and short term efficacy of rituximab in 43 patients with systemic autoimmune diseases
Gottenberg, J, Guillevin, L, Lambotte, O, Combe, B, Allanore, Y, Cantagrel, A, ...
Objective: To assess the tolerance and efficacy of rituximab in patients with various autoimmune diseases seen in daily rheumatological practice.
Wanders, A, Landewe, R, Dougados, M, Mielants, H
Objective: To demonstrate the association between various measures of spinal mobility and radiographic damage of the spine in individual patients with ankylosing spondylitis, and to determine whether...
Gossec, L, Tubach, F, Baron, G, Ravaud, P, Logeart, I, Dougados, M
Objectives: To determine the 2 year total hip replacement (THR) rate and to identify factors predictive of THR due to primary osteoarthritis (OA).
Briot, K, Garnero, P, Le Henanff, A, Dougados, M, Roux, C
Objectives: To determine the changes in body weight, body composition, and bone turnover in patients with spondyloarthropathy (SpA) treated with anti-tumour necrosis factor α (TNFα).
Sustained durability and tolerability of etanercept in ankylosing spondylitis for 96 weeks
Davis, J, Van Der Heijde, D M, Braun, J, Dougados, M, Cush, J, Clegg, D, ...
Objective: To evaluate the continued safety and durability of clinical response in patients with ankylosing spondylitis receiving etanercept.
Gossec, L, Melian, A, Krupa, D, James, M, Cavanaugh, P, ...
Objective: The combined efficacy of selective and non-selective cyclo-oxygenase-2 (COX-2) inhibition on the axial manifestations of ankylosing spondylitis (AS) in the presence or absence of chronic...
Furst, D, Breedveld, F, Kalden, J, Smolen, J, Burmester, G, Bijlsma, J, ...
D'Agostino, M, Conaghan, P, Le Bars, M, Baron, G, Grassi, W, Martin-Mola, E, ...
Objectives: To assess the prevalence of inflammation in subjects with chronic painful knee osteoarthritis (OA), as determined by the presence of synovitis or joint effusion at ultrasonography (US);...
Conaghan, P, D'Agostino, M, Ravaud, P, Baron, G, Le Bars, M, Grassi, W, ...
Background: Synovial inflammation (as defined by hypertrophy and effusion) is common in osteoarthritis (OA) and may be important in both pain and structural progression.
Mazières, B, Garnero, P, Guéguen, A, Abbal, M, Berdah, L, Lequesne, M, ...
ASAS/EULAR recommendations for the management of ankylosing spondylitis
Zochling, J, Burgos‐Vargas, R, Collantes, E, Davis, J C, Dijkmans, B, ...
Wells, G, Becker, J-C, Teng, J, Dougados, M, Schiff, M, Smolen, J, ...
Determinants of hyperkyphosis in patients with ankylosing spondylitis
Vosse, D, Landewé, R, Geusens, P, Mielants, H, Dougados, M, ...
Definition of disease duration in ankylosing spondylitis: reassessing the concept
Davis, J C, Dougados, M, Braun, J, Sieper, J
The concept and definition of disease duration in patients with ankylosing spondylitis is ambiguous, and often many years pass between the onset of symptoms and diagnosis. Members of the Assessment...