Clonal relationships among bloodstream isolates of Escherichia coli.
Maslow, J N, Whittam, T S, Gilks, C F, Wilson, R A, Mulligan, M E, Adams, K S, ...
The clonal relationships among 187 bloodstream isolates of Escherichia coli from 179 patients at Boston, Mass., Long Beach, Calif., and Nairobi, Kenya, were determined by multilocus enzyme...
Lambertus, M W, Kwok, R Y, Mulligan, M E
The in vitro activity of trimethoprim plus dapsone against oxacillin-resistant Staphylococcus aureus was comparable to that of trimethoprim plus sulfamethoxazole. Because of its different...
Mulligan, M E, Citron, D, Gabay, E, Kirby, B D, George, W L, Finegold, S M
To evaluate the effects of parenteral cefoxitin therapy on human fecal flora, we cultured fecal specimens obtained from six patients before, during, and after therapy and used standard methods to...
GlbN (cyanoglobin) is a peripheral membrane protein that is restricted to certain Nostoc spp.
Hill, D R, Belbin, T J, Thorsteinsson, M V, Bassam, D, Brass, S, Ernst, A, ...
The glbN gene of Nostoc commune UTEX 584 is juxtaposed to nifU and nifH, and it encodes a 12-kDa monomeric hemoglobin that binds oxygen with high affinity. In N. commune UTEX 584, maximum...
Soltes-Rak, E, Mulligan, M E, Coleman, J R
A gene (designated ecaA) encoding a vertebrate-like (alpha-type) carbonic anhydrase (CA) has been isolated from two disparate cyanobacteria, Anabaena sp. strain PCC 7120 and Synechococcus sp. strain...
Intravenous metronidazole for treatment of infections involving anaerobic bacteria.
George, W L, Kirby, B D, Sutter, V L, Wheeler, L A, Mulligan, M E, Finegold, S M
Intravenous metronidazole was administered, either by continuous or intermittent infusion, to 20 patients with infections involving anaerobic bacteria; 14 of the 20 patients were changed to oral...
Impact of cefoperazone therapy on fecal flora.
Mulligan, M E, Citron, D M, McNamara, B T, Finegold, S M
To evaluate the effects of parenteral cefoperazone therapy upon human fecal flora, fecal specimens obtained from four patients before and during therapy (as well as after therapy for one patient)...
Resistance of gram-negative bacilli as related to hospital use of antimicrobial agents.
Ma, M Y, Goldstein, E J, Friedman, M H, Anderson, M S, Mulligan, M E
The development of resistance of gram-negative bacilli, which are common nosocomial pathogens, is an increasing problem. It is generally accepted that this resistance may directly reflect the...
Walsh, T J, Standiford, H C, Reboli, A C, John, J F, Mulligan, M E, Ribner, B S, ...
Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen in hospitals. Current antimicrobial regimens for eradicating colonizing strains are not well defined and are often complicated...
Mulligan, M E, Buikema, W J, Haselkorn, R
The nucleotide sequence of a region located downstream of the nifB gene, both in the cyanobacterium Anabaena sp. strain PCC 7120 and in Rhizobium meliloti, has been determined. This region contains a...
Golden, J W, Carrasco, C D, Mulligan, M E, Schneider, G J, Haselkorn, R
The filamentous cyanobacterium Anabaena sp. strain PCC 7120 produces terminally differentiated heterocysts in response to a lack of combined nitrogen. Heterocysts are found approximately every 10th...
Hartstein, A I, Phelps, C L, Kwok, R Y, Mulligan, M E
We evaluated test discriminatory power and DNA type alterations among methicillin-resistant Staphylococcus aureus strains by testing 199 sequential isolates from 39 patients collected over 30 to 228...
Tang, Y J, Houston, S T, Gumerlock, P H, Mulligan, M E, Gerding, D N, Johnson, S, ...
Arbitrarily primed PCR (AP-PCR) was used to genotype 26 clinical isolates of Clostridium difficile previously analyzed by immunoblotting (IB) and 20 isolates typed by restriction endonuclease...
McFarland, L V, Elmer, G W, Stamm, W E, Mulligan, M E
To determine whether strain-specific differences in immunoblot type, enterotoxin production, or cytotoxin production correlated with clinical presentation of Clostridium difficile infection, we...
Recurrent Escherichia coli bacteremia.
Maslow, J N, Mulligan, M E, Arbeit, R D
Escherichia coli is the most common gram-negative organism associated with bacteremia. While recurrent E. coli urinary tract infections are well-described, recurrent E. coli bacteremia appears to be...
Recurrent Staphylococcus aureus bacteremia.
Hartstein, A I, Mulligan, M E, Morthland, V H, Kwok, R Y
Sequential blood isolates from eight patients with 10 episodes of recurrent Staphylococcus aureus bacteremia were typed by restriction endonuclease analysis of plasmid DNA (REAP DNA fingerprinting)...
Clabots, C R, Johnson, S, Bettin, K M, Mathie, P A, Mulligan, M E, Schaberg, D R, ...
A HindIII restriction endonuclease analysis (REA) typing system for total genomic Clostridium difficile DNA including a rapid and efficient method of DNA extraction and a scheme for organizing unique...
Mulligan, M E, Citron, D M, Kwok, R Y, Wheelock, J P, Farrohi, F K, Hindler, J A, ...
Because strains of Staphylococcus aureus that are resistant to penicillinase-resistant penicillins may be difficult to detect in the clinical laboratory, a variety of changes in methodology have been...
Mulligan, M E, Peterson, L R, Kwok, R Y, Clabots, C R, Gerding, D N
Two new methods for typing Clostridium difficile, immunoblotting and plasmid fingerprinting, were compared with serotyping and polyacrylamide gel electrophoresis (PAGE). Of these methods,...
Mulligan, M E, Kwok, R Y, Citron, D M, John, J F, Smith, P B
An immunoblotting system was developed for typing of oxacillin-resistant Staphylococcus aureus. Clinical isolates recovered during a 40-month period at a single institution were evaluated with this...
Bacteroides gracilis, an important anaerobic bacterial pathogen.
Johnson, C C, Reinhardt, J F, Edelstein, M A, Mulligan, M E, George, W L, Finegold, S M
Clinical isolates of agar-pitting, formate-fumarate-requiring, anaerobic gram-negative bacilli were recharacterized in consideration of the species descriptions of Bacteroides ureolyticus and the...
Failure of rapid agglutination methods to detect oxacillin-resistant Staphylococcus aureus.
Ruane, P J, Morgan, M A, Citron, D M, Mulligan, M E
Although a latex agglutination test (StaphAurex) and a hemagglutination test (Staphyloslide) correctly identified all strains of Staphylococcus aureus that were susceptible or had intermediate...
Escherichia coli promoter sequences predict in vitro RNA polymerase selectivity.
Mulligan, M E, Hawley, D K, Entriken, R, McClure, W R
We describe a simple algorithm for computing a homology score for Escherichia coli promoters based on DNA sequence alone. The homology score was related to 31 values, measured in vitro, of RNA...
Analysis of the occurrence of promoter-sites in DNA.
We show that the occurrence and homology score (1) of promoter-sites in DNA depends upon the base composition of the DNA. We used simple probability theory to calculate the mean homology score...
Clonal relationships among bloodstream isolates of Escherichia coli.
Maslow, J N, Whittam, T S, Gilks, C F, Wilson, R A, Mulligan, M E, Adams, K S, ...
The clonal relationships among 187 bloodstream isolates of Escherichia coli from 179 patients at Boston, Mass., Long Beach, Calif., and Nairobi, Kenya, were determined by multilocus enzyme...
Lambertus, M W, Kwok, R Y, Mulligan, M E
The in vitro activity of trimethoprim plus dapsone against oxacillin-resistant Staphylococcus aureus was comparable to that of trimethoprim plus sulfamethoxazole. Because of its different...
Mulligan, M E, Citron, D, Gabay, E, Kirby, B D, George, W L, Finegold, S M
To evaluate the effects of parenteral cefoxitin therapy on human fecal flora, we cultured fecal specimens obtained from six patients before, during, and after therapy and used standard methods to...
GlbN (cyanoglobin) is a peripheral membrane protein that is restricted to certain Nostoc spp.
Hill, D R, Belbin, T J, Thorsteinsson, M V, Bassam, D, Brass, S, Ernst, A, ...
The glbN gene of Nostoc commune UTEX 584 is juxtaposed to nifU and nifH, and it encodes a 12-kDa monomeric hemoglobin that binds oxygen with high affinity. In N. commune UTEX 584, maximum...
Soltes-Rak, E, Mulligan, M E, Coleman, J R
A gene (designated ecaA) encoding a vertebrate-like (alpha-type) carbonic anhydrase (CA) has been isolated from two disparate cyanobacteria, Anabaena sp. strain PCC 7120 and Synechococcus sp. strain...
Intravenous metronidazole for treatment of infections involving anaerobic bacteria.
George, W L, Kirby, B D, Sutter, V L, Wheeler, L A, Mulligan, M E, Finegold, S M
Intravenous metronidazole was administered, either by continuous or intermittent infusion, to 20 patients with infections involving anaerobic bacteria; 14 of the 20 patients were changed to oral...
Impact of cefoperazone therapy on fecal flora.
Mulligan, M E, Citron, D M, McNamara, B T, Finegold, S M
To evaluate the effects of parenteral cefoperazone therapy upon human fecal flora, fecal specimens obtained from four patients before and during therapy (as well as after therapy for one patient)...
Resistance of gram-negative bacilli as related to hospital use of antimicrobial agents.
Ma, M Y, Goldstein, E J, Friedman, M H, Anderson, M S, Mulligan, M E
The development of resistance of gram-negative bacilli, which are common nosocomial pathogens, is an increasing problem. It is generally accepted that this resistance may directly reflect the...
Walsh, T J, Standiford, H C, Reboli, A C, John, J F, Mulligan, M E, Ribner, B S, ...
Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen in hospitals. Current antimicrobial regimens for eradicating colonizing strains are not well defined and are often complicated...
Mulligan, M E, Buikema, W J, Haselkorn, R
The nucleotide sequence of a region located downstream of the nifB gene, both in the cyanobacterium Anabaena sp. strain PCC 7120 and in Rhizobium meliloti, has been determined. This region contains a...
Golden, J W, Carrasco, C D, Mulligan, M E, Schneider, G J, Haselkorn, R
The filamentous cyanobacterium Anabaena sp. strain PCC 7120 produces terminally differentiated heterocysts in response to a lack of combined nitrogen. Heterocysts are found approximately every 10th...
Hartstein, A I, Phelps, C L, Kwok, R Y, Mulligan, M E
We evaluated test discriminatory power and DNA type alterations among methicillin-resistant Staphylococcus aureus strains by testing 199 sequential isolates from 39 patients collected over 30 to 228...
Tang, Y J, Houston, S T, Gumerlock, P H, Mulligan, M E, Gerding, D N, Johnson, S, ...
Arbitrarily primed PCR (AP-PCR) was used to genotype 26 clinical isolates of Clostridium difficile previously analyzed by immunoblotting (IB) and 20 isolates typed by restriction endonuclease...
McFarland, L V, Elmer, G W, Stamm, W E, Mulligan, M E
To determine whether strain-specific differences in immunoblot type, enterotoxin production, or cytotoxin production correlated with clinical presentation of Clostridium difficile infection, we...
Recurrent Escherichia coli bacteremia.
Maslow, J N, Mulligan, M E, Arbeit, R D
Escherichia coli is the most common gram-negative organism associated with bacteremia. While recurrent E. coli urinary tract infections are well-described, recurrent E. coli bacteremia appears to be...
Recurrent Staphylococcus aureus bacteremia.
Hartstein, A I, Mulligan, M E, Morthland, V H, Kwok, R Y
Sequential blood isolates from eight patients with 10 episodes of recurrent Staphylococcus aureus bacteremia were typed by restriction endonuclease analysis of plasmid DNA (REAP DNA fingerprinting)...
Clabots, C R, Johnson, S, Bettin, K M, Mathie, P A, Mulligan, M E, Schaberg, D R, ...
A HindIII restriction endonuclease analysis (REA) typing system for total genomic Clostridium difficile DNA including a rapid and efficient method of DNA extraction and a scheme for organizing unique...
Mulligan, M E, Citron, D M, Kwok, R Y, Wheelock, J P, Farrohi, F K, Hindler, J A, ...
Because strains of Staphylococcus aureus that are resistant to penicillinase-resistant penicillins may be difficult to detect in the clinical laboratory, a variety of changes in methodology have been...
Mulligan, M E, Peterson, L R, Kwok, R Y, Clabots, C R, Gerding, D N
Two new methods for typing Clostridium difficile, immunoblotting and plasmid fingerprinting, were compared with serotyping and polyacrylamide gel electrophoresis (PAGE). Of these methods,...
Mulligan, M E, Kwok, R Y, Citron, D M, John, J F, Smith, P B
An immunoblotting system was developed for typing of oxacillin-resistant Staphylococcus aureus. Clinical isolates recovered during a 40-month period at a single institution were evaluated with this...
Bacteroides gracilis, an important anaerobic bacterial pathogen.
Johnson, C C, Reinhardt, J F, Edelstein, M A, Mulligan, M E, George, W L, Finegold, S M
Clinical isolates of agar-pitting, formate-fumarate-requiring, anaerobic gram-negative bacilli were recharacterized in consideration of the species descriptions of Bacteroides ureolyticus and the...
Failure of rapid agglutination methods to detect oxacillin-resistant Staphylococcus aureus.
Ruane, P J, Morgan, M A, Citron, D M, Mulligan, M E
Although a latex agglutination test (StaphAurex) and a hemagglutination test (Staphyloslide) correctly identified all strains of Staphylococcus aureus that were susceptible or had intermediate...
Escherichia coli promoter sequences predict in vitro RNA polymerase selectivity.
Mulligan, M E, Hawley, D K, Entriken, R, McClure, W R
We describe a simple algorithm for computing a homology score for Escherichia coli promoters based on DNA sequence alone. The homology score was related to 31 values, measured in vitro, of RNA...
Analysis of the occurrence of promoter-sites in DNA.
We show that the occurrence and homology score (1) of promoter-sites in DNA depends upon the base composition of the DNA. We used simple probability theory to calculate the mean homology score...