Tanikawa, J, Yasukawa, T, Enari, M, Ogata, K, Nishimura, Y, Ishii, S, ...
The DNA-binding domain of c-Myb consists of three homologous tandem repeats of 52 amino acids. The structure of the third (C-terminal) repeat obtained by NMR analysis has a conformation related to...
Weissmann, C., Enari, M., Klöhn, P.-C., Rossi, D., Flechsig, E.
The “protein only” hypothesis states that the infectious agent causing transmissible spongiform encephalopathies is a conformational isomer of PrP, a host protein predominantly expressed in...
A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions
Klöhn, P.-C., Stoltze, L., Flechsig, E., Enari, M., Weissmann, C.
Prions are usually quantified by bioassays based on intracerebral inoculation of mice that are slow, imprecise, and costly. We have isolated neuroblastoma N2a sublines highly susceptible to mouse...
Apoptosis by a cytosolic extract from Fas-activated cells.
Fas is a type I membrane protein and its activation by binding of the Fas ligand or an agonistic anti-Fas antibody induces apoptosis in Fas-bearing cells. In this report we prepared lysates from...
Involvement of Fas in regression of vaginal epithelia after ovariectomy and during an estrous cycle.
Suzuki, A, Enari, M, Eguchi, Y, Matsuzawa, A, Nagata, S, Tsujimoto, Y, ...
Fas, also called APO-1, belongs to the tumor necrosis factor/nerve growth factor receptor family and transmits an apoptotic signal within the cell by binding to the Fas ligand. Fas has been...
Tanikawa, J, Yasukawa, T, Enari, M, Ogata, K, Nishimura, Y, Ishii, S, ...
The DNA-binding domain of c-Myb consists of three homologous tandem repeats of 52 amino acids. The structure of the third (C-terminal) repeat obtained by NMR analysis has a conformation related to...
Weissmann, C., Enari, M., Klöhn, P.-C., Rossi, D., Flechsig, E.
The “protein only” hypothesis states that the infectious agent causing transmissible spongiform encephalopathies is a conformational isomer of PrP, a host protein predominantly expressed in...
A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions
Klöhn, P.-C., Stoltze, L., Flechsig, E., Enari, M., Weissmann, C.
Prions are usually quantified by bioassays based on intracerebral inoculation of mice that are slow, imprecise, and costly. We have isolated neuroblastoma N2a sublines highly susceptible to mouse...
Apoptosis by a cytosolic extract from Fas-activated cells.
Fas is a type I membrane protein and its activation by binding of the Fas ligand or an agonistic anti-Fas antibody induces apoptosis in Fas-bearing cells. In this report we prepared lysates from...
Involvement of Fas in regression of vaginal epithelia after ovariectomy and during an estrous cycle.
Suzuki, A, Enari, M, Eguchi, Y, Matsuzawa, A, Nagata, S, Tsujimoto, Y, ...
Fas, also called APO-1, belongs to the tumor necrosis factor/nerve growth factor receptor family and transmits an apoptotic signal within the cell by binding to the Fas ligand. Fas has been...
Transmission of scrapie by steel-surface-bound prions.
Flechsig, E., Hegyi, I., Enari, M., Schwarz, P., Collinge, J., Weissmann, C.
BACKGROUND: Prions are unusually resistant to conventional disinfection procedures. An electrode used intracerebrally on a Creutzfeldt-Jakob disease (CJD) patient transmitted the disease to two...
Infectivity of scrapie prions bound to a stainless steel surface.
Zobeley, E., Flechsig, E., Cozzio, A., Enari, M., Weissmann, C.
BACKGROUND: The transmissible agent of Creutzfeldt-Jakob disease (CJD) is not readily destroyed by conventional sterilization and transmissions by surgical instruments have been reported....