M. Fesen

Intermolecular disintegration and intramolecular strand transfer activities of wild-type and mutant HIV-1 integrase.

Mazumder, A, Engelman, A, Craigie, R, Fesen, M, Pommier, Y

We report the activities of HIV integrase protein on a novel DNA substrate, consisting of a pair of gapped duplex molecules. Integrase catalyzed an intermolecular disintegration reaction that...

Intermolecular disintegration and intramolecular strand transfer activities of wild-type and mutant HIV-1 integrase.

Mazumder, A, Engelman, A, Craigie, R, Fesen, M, Pommier, Y

We report the activities of HIV integrase protein on a novel DNA substrate, consisting of a pair of gapped duplex molecules. Integrase catalyzed an intermolecular disintegration reaction that...