M. Göttlicher

Publication List Details

Period

1987 - 2008

Number

86

Co-Authors

Ah (dioxin) receptor induces c-jun expression via a novel p38-MAPK-dependent pathway. (2004)

Weiss, C., Kolluri, S.K., Durk, H., Pelzer, A., Oesch, F., Göttlicher, M.

45.Frühjahrstagung der Deutschen Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie (DGPT), Mainz, 9.-11.März 2004

The HDAC inhibitor valproic acid selectively induces proteasomal degradation of HDAC2. (2003)

Krämer, O.H., Zhu, P., Ostendorff, H.P., Golebiewski, M., Tiefenbach, J., Peters, M.A., ...

Keystone Meeting 'Enzymology of Chromatine and Transcription', Santa Fe, N.M., March 10-13, 2003

The teratogen valproic acid is a selective inhibitor of a subset of histone deacetylases. (2002)

Zhu, P., Krämer, O.H., Heinzel, T., Göttlicher, M.

43.Frühjahrstagung der Deutschen Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie (DGPT), Mainz, 12.-14.März 2002

The teratogen valproic acid defines a novel class of histone deacetylase inhibitors inducing differentiation of embryonic, transformed and tumorigenic cells. (2002)

Göttlicher, M., Minucci, S., Zhu, P., Krämer, O.H., Schimpf, A., Giavara, S., ...

43.Frühjahrstagung der Deutschen Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie (DGPT), Mainz, 12.-14.März 2002

Identification of novel factors involved in AP-1 repression. (2001)

Schneider, S., Heilbock, C., Göttlicher, M., Herrlich, P.

Keystone Symp.on Mechanisms of Eukaryotic Transcriptional Regulation, Keystone, Colo., February 26 - March 4, 2001

Redox regulation in mammalian signal transduction. (2001)

Herrlich, P., Klöhn, P.C., Göttlicher, M., Böhmer, F.

Workshop on Redox Signalling in Proliferate Disorders, Roma, I, June 21, 2001

Histone deacetylase as a therapeutic target. (2001)

Krämer, O.H., Göttlicher, M., Heinzel, T.

Trends in Endocrinology and Metabolism, 12(2001) S.294-300

Redox regulation of signal transduction in mammalian cells. (2001)

Göttlicher, M., Böhmer, F.D., Herrlich, P.

21st World Congress of Pathology and Laboratory Medicine, Düsseldorf, November 20-23, 2001

Cell cycle regulation by the Ah receptor. (2001)

Göttlicher, M., Weiss, C., Balduf, C., Kolluri, S.K.

14.Heidelberger Cytometrie-Symp., Heidelberg, 18.-20.Oktober 2001

Molecular reactions of dioxin. (2000)

Göttlicher, M., Kolluri, S.K., Balduf, C., Weiss, C.

8th KBF Symp.Complexity in Medicine, Köln, September 13-15, 2000

Tin alkyl compounds as signal molecules. The induction of programmed cell death. (2000)

Krug, H.F., Klöhn, P.C., Göttlicher, M., Herrlich, P.

Herbsttagung der Gesellschaft für Biochemie und Molekulare Biologie (GBM), München, 10.-13.Oktober 2000

Ah (Dioxin) receptor and hypoxia inducible factors (HIFs) in the cellular response to environmental conditions. (2000)

Göttlicher, M., Kolluri, K.S., Balduf, C., Weiss, C.

6th Internat.Dahlem Symp.on Cellular Signal Recognition and Transduction and Fall Meeting of the German Society of Experimental and Clinical Pharmacology and Toxicology, Berlin, September 27-30, 2000

Ligand-independent Fas receptor activation by tributyltin. (2000)

Klöhn, P.C., Krug, H.F., Meixner, S., Göttlicher, M., Herrlich, P.

Meeting on Signal Transduction: Receptors, Mediators and Genes, Berlin, November 2-4, 2000

Radiation-induced signal transduction. (1999)

Göttlicher, M., Bender, K., Knebel, A., Krug, H., Böhmer, F., Herrlich, P.

27th Annual Meeting of the American Society for Photobiology, Washington, D.C., July 10-15, 1999

Cell cycle regulation by the Ah receptor. (1999)

Göttlicher, M., Pelzer, A., Litfin, M., Kolluri, S.K., Weiss, C.

DIOXIN 99 : 19th Internat.Symp.on Halogenated Environmental Organic Pollutants and Persistent Organic Pollutants (POPs), Venezia, I, September 12-17, 1999

p27`k`i`p`1 induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells. (1999)

Weiss, C., Kolluri, S.K., Koff, A., Göttlicher, M.

The Salk Institute for Biological Studies - Oncogene and Growth Control Meeting, La Jolla, Calif., August 18-22, 1999

Cell cycle control by dioxins is mediated by induction of the p27`K`i`p`1 inhibitory protein. (1998)

Kolluri, S.K., Weiss, C., Göttlicher, M.

39.Frühjahrstagung der Deutschen Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie (DGPT), Mainz, 17.-19.März 1998

Cellular actions of valproic acid and its teratogenic derivates: activation of peroxisome proliferator activeted receptors (PPARs) and differentiation of teratocarcinoma cells. (1998)

Göttlicher, M., Werling, U., Siehler, S., Ellerbeck, U., Nau, H.

Wintertagung der Deutschen Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie (DGPT) '30 Jahre Zentrum Pharmakologie und Toxikologie der Medizinischen Hochschule Hannover',...

Retroviral expression of Ah receptor reconstitutes TCDD-sensitivity in receptor-deficient hepatoma cells. (1996)

Weiss, C., Kolluri, K., Kiefer, F., Göttlicher, M.

37.Frühjahrstagung der Deutschen Gesellschaft für Pharmakologie und Toxikologie, Mainz, 12.-14.Mäerz 1996

Signal transduction to transcription factors. (1996)

Herrlich, P., Heck, S., Göttlicher, M., Knebel, A., Rahmsdorf, H.J.

Internat.Summer School on Mechanisms in Eukaryotic Gene Regulation, Spetses, GR, September 2-12, 1996

Reconstitution of responsiveness to 2,3,7,8-tetra-chlorodibenzo-p-dioxin (TCDD) in yeast and in Ah receptor-impaired hepatoma cells. (1995)

Weiss, C., Kiefer, F., Göttlicher, M.

36.Frühjahrstagung der Deutschen Gesellschaft für experimentelle klinische Pharmakologie und Toxikologie, Mainz, 14.-16.Mäerz 1995

Dissociation of positively and negatively regulating functions of nuclear receptors. (1995)

Göttlicher, M., Heck, S., Herrlich, P., Cato, A.C.B.

EMBO Workshop: Structure and Function of Steroid and Nuclear Receptors, Porto Conte, I, April 27-30, 1995

Regulation of AP-1 activity and of AP-1-dependent target genes. (1995)

Iordanov, M., Wade, E., Knebel, A., Angel, P., Rahmsdorf, H.J., Wilhelm, D., ...

5th Internat.Congress: Hormones and Cancer, Quebec, CDN, September 16-20, 1995

The level of aryl hydrocarbon (Ah) receptor and of 4S polycyclic aromatic hydrocarbon (PAH) binding protein in diploid and polyploid hepatocytes of 2-acetylaminofluorene-treated rats (1992)

Cikryt, P., Göttlicher, M., Veser, U., Schwarz, L.R.

Sequential treatment of partially hepatectomized male Wistar rats with diethylnitrosamine (DEN) and 2-acetylamino-fluorene (AAF) induces the emergence of diploid hepatocyte populations. These...

Competitive binding affinity of carcinogenic aromatic amines to the rat hepatic aromatic hydrocarbon (Ah) receptor in vitro and potency to induce monooxygenase activity in vivo (1990)

Cikryt, P., Göttlicher, M.

The aromatic amides 2-acetylaminofluorene (2-AAF), its isomer 4-acetylaminofluorene, 2-acetylaminophenanthrene (AAP), trans-4-acetylaininostilbene (AAS) and the corresponding amines differ in their...

Induction of the aromatic hydrocarbon receptor by trans-4-acetylaminostilbene in rat liver. Comparison with other aromatic amines (1987)

Göttlicher, M., Cikryt, P.

The effect of the aromatic amines 2-acetylaminofluorene (AAF), 2-acetylaminopbenanthrene (AAP) and trans-4-acetyl-aminostilbene (AAS) on the rat hepatic aromatic hydrocarbon (Ah) receptor level was...

Interaction of the peroxisome-proliferator-activated receptor and retinoid X receptor.

Gearing, K L, Göttlicher, M, Teboul, M, Widmark, E, Gustafsson, J A

The rat peroxisome-proliferator-activated receptor (PPAR) was expressed in insect cells and was shown to bind to a cognate PPAR response element (PPRE) from the acyl-CoA oxidase gene. Upon...

Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor.

Göttlicher, M, Widmark, E, Li, Q, Gustafsson, J A

Peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643 have been shown to activate PPAR (peroxisome proliferator-activated receptor), a member of the steroid nuclear receptor...

Definition of a novel ligand binding domain of a nuclear bHLH receptor: co-localization of ligand and hsp90 binding activities within the regulable inactivation domain of the dioxin receptor.

Whitelaw, M L, Göttlicher, M, Gustafsson, J A, Poellinger, L

The dioxin receptor mediates signal transduction by dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) and binds to DNA target sequences as a heterodimer of the approximately 100 kDa ligand binding...

I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.

Heck, S, Bender, K, Kullmann, M, Göttlicher, M, Herrlich, P, Cato, A C

I kappaB alpha is an inhibitor protein that prevents nuclear transport-and activation of the transcription factor NF-kappaB. In acute inflammation, NF-kappaB is activated and increases the expression...

Sequential DNA damage-independent and -dependent activation of NF-kappaB by UV.

Bender, K, Göttlicher, M, Whiteside, S, Rahmsdorf, H J, Herrlich, P

NF-kappaB activation in response to UV irradiation of HeLa cells or of primary human skin fibroblasts occurs with two overlapping kinetics but totally different mechanisms. Although both mechanisms...

In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation.

Berge, R K, Madsen, L, Vaagenes, H, Tronstad, K J, Göttlicher, M, Rustan, A C

Hypolipidaemic fatty acid derivatives and polyunsaturated fatty acids decrease concentrations of plasma triacylglycerol by mechanisms that are not fully understood. Because poor susceptibility to...

Binding of aromatic amines to the rat hepatic Ah receptor in vitro and in vivo and to the 8S and 4S estrogen receptor of rat uterus and rat liver.

Cikryt, P, Kaiser, T, Göttlicher, M

Studies on structurally related aromatic amines with different carcinogenic properties have shown that 2-acetylaminofluorene (2-AAF) and 2-acetylaminophenanthrene (AAP) inhibit the binding of...

Interaction of the peroxisome-proliferator-activated receptor and retinoid X receptor.

Gearing, K L, Göttlicher, M, Teboul, M, Widmark, E, Gustafsson, J A

The rat peroxisome-proliferator-activated receptor (PPAR) was expressed in insect cells and was shown to bind to a cognate PPAR response element (PPRE) from the acyl-CoA oxidase gene. Upon...

Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor.

Göttlicher, M, Widmark, E, Li, Q, Gustafsson, J A

Peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643 have been shown to activate PPAR (peroxisome proliferator-activated receptor), a member of the steroid nuclear receptor...

Definition of a novel ligand binding domain of a nuclear bHLH receptor: co-localization of ligand and hsp90 binding activities within the regulable inactivation domain of the dioxin receptor.

Whitelaw, M L, Göttlicher, M, Gustafsson, J A, Poellinger, L

The dioxin receptor mediates signal transduction by dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) and binds to DNA target sequences as a heterodimer of the approximately 100 kDa ligand binding...

I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.

Heck, S, Bender, K, Kullmann, M, Göttlicher, M, Herrlich, P, Cato, A C

I kappaB alpha is an inhibitor protein that prevents nuclear transport-and activation of the transcription factor NF-kappaB. In acute inflammation, NF-kappaB is activated and increases the expression...

Sequential DNA damage-independent and -dependent activation of NF-kappaB by UV.

Bender, K, Göttlicher, M, Whiteside, S, Rahmsdorf, H J, Herrlich, P

NF-kappaB activation in response to UV irradiation of HeLa cells or of primary human skin fibroblasts occurs with two overlapping kinetics but totally different mechanisms. Although both mechanisms...

In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation.

Berge, R K, Madsen, L, Vaagenes, H, Tronstad, K J, Göttlicher, M, Rustan, A C

Hypolipidaemic fatty acid derivatives and polyunsaturated fatty acids decrease concentrations of plasma triacylglycerol by mechanisms that are not fully understood. Because poor susceptibility to...

Binding of aromatic amines to the rat hepatic Ah receptor in vitro and in vivo and to the 8S and 4S estrogen receptor of rat uterus and rat liver.

Cikryt, P, Kaiser, T, Göttlicher, M

Studies on structurally related aromatic amines with different carcinogenic properties have shown that 2-acetylaminofluorene (2-AAF) and 2-acetylaminophenanthrene (AAP) inhibit the binding of...

Valproic acid (VPA) in patients with refractory advanced cancer: a dose escalating phase I clinical trial

Atmaca, A, Al-Batran, S-E, Maurer, A, Neumann, A, Heinzel, T, Hentsch, B, ...

Altered histone deacetylase (HDAC) activity has been identified in several types of cancer. This study was designed to determine the safety and maximum tolerated dose (MTD) of valproic acid (VPA) as...