M. G. Dell'Oro

Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations (2006)

Cazzaniga, G, Alberti, F, Dell'Oro, M G, Gottardi, E, Specchia, G, ...

Mutations in exon 12 of the nucleophosmin (NPM1) gene occur in about 60% of adult AML with normal karyotype. By exploiting a specific feature of NPM1 mutants, that is insertion at residue 956 or...