Boshoff, D E, ...
OBJECTIVE: Interventional targets may be virtually "excluded" due to vascular access problems or complex previous surgical procedures. This study reviews our experience using transapical ventricular...
Email Alerting, A Rauch, K Devriendt, A Koch, R Rauch, M Gewillig, ...
service
Dragusin, O., Gewillig, M., Desmet, W., Smans, K., Struelens, L., Bosmans, H.
Flat-panel X-ray detectors for fluoroscopy represent a modern imaging equipment that is being implemented in paediatric cardiac catheterisation laboratories. Infants and children represent a group of...
Collaboratively charting the gene-to-phenotype network of human congenital heart defects (2008)
Breckpot, J, Thienpont, B, ...
Acute cardiac functional and morphological changes after anthracycline infusions in children (2007)
Uyttebroeck, A, Renard, M, ...
American journal of cardiology, vol. 99, no. 7, pp. 974-977, 2007
Een Belgische patiënt met Arterial Tortuosity Syndrome (2007)
CALLEWAERT, BERT, Loeys, Bart, De Backer, Julie, Willaert, Andy, DEVOS, D, GEWILLIG, M, ...
Mertens, L, ...
OBJECTIVE: To determine the safety, feasibility and effectiveness of stent expansion of hypoplastic aortic segments with pressure gradients in patients with arterial hypertension. DESIGN:...
Barrea, C, De Wolf, D, Gewillig, M, Massin, M, Mertens, L, ...
Sports camps for children with cardiac anomalies have existed for many years. However, no formal evaluation of the benefits of attending such camps has been undertaken heretofore. We assessed...
OBJECTIVE: To explore whether the severity of congenital heart disease is associated with the quality of life and perceived health status of adult patients. DESIGN: Descriptive, cross sectional...
Taylor, A.M., Dymarkowski, S., Hamaekers, P., Razavi, R., Gewillig, M., Mertens, L., ...
Purpose: To prospectively evaluate the feasibility of magnetic resonance (MR) coronary artery imaging and to define myocardial damage with late-enhancement myocardial MR imaging in children who...
Short term complications of branch pulmonary artery stenting: a multicenter study (2005)
WITSENBURG, M, GEWILLIG, M, VAN GAMEREN, M, FREUND, M, BOKENKAMP, R, De Wolf, Daniël, ...
724 The acute effect of anthracyclines on cardiac function assessed with strain rate imaging (2005)
Ganame, J., Claus, P., Uyltebroeck, A., Renard, M., Dhooge, J., Bilnens, B., ...
Velocardiofacial syndrome presenting as distal arthrogryposis (2004)
Swillen, A., Gewillig, M., Fryns, J.P., De Smet, L
We report on a child with the velocardiofacial syndrome (deletion in chromosome 22q11.2) presenting with camptodactyly and club feet. This further illustrates the wide variation in clinical...
Moons, P, Gewillig, M, Sluysmans, T, Verhaaren, H, Viart, P, Massin, M, ...
Objective: To assess long term outcome of patients who underwent Mustard or Senning repair for transposition of the great arteries up to 30 years earlier. Design: Retrospective review of medical...
Gewillig, M, Sluysmans, T, Verhaaren, H, Viart, P, Massin, M, ...
OBJECTIVE: To assess long term outcome of patients who underwent Mustard or Senning repair for transposition of the great arteries up to 30 years earlier. DESIGN: Retrospective review of medical...
DI SALVO, G, EYSKENS, B, CLAUS, P, D'HOOGE, J, BIJNENS, B, SUYS, B, ...
Haemoptysis may occur in patients with tetralogy of Fallot and major aorto-pulmonary collateral arteries. We describe such a patient in whom bleeding from a major aorto-pulmonary collateral artery...
Modified technique of stent fenestration of the atrial septum (2003)
Gewillig, M, Vettukattil, J, Chessa, M, Chaudhari, M, ...
OBJECTIVES: To develop a modified technique for stenting the atrial septum in the treatment of patients with a failing Fontan operation or pulmonary hypertension. SETTING: Two tertiary referral...
Balloon dilatation of coarctation and recoarctation (2003)
Gasthuiberg University Hospital, Leuven, Belgium.
Immediate and intermediate term results of stent therapy for aortic coarctation (2003)
HONING-HEMMERS, A, VAN PUTTEN, W, GEWILLIG, M, DE WOLFF, D, TALSMA, M, MAST, G, ...
Immediate and intermediate results of stent therapy for aortic coarctation (2003)
HONING-HEMMERS, A, VAN PUTTEN, W, GEWILLIG, M, MAST, F, TALSMA, M, TANKE, R, ...
Rheology of discrete subaortic stenosis (2002)
The discrete form of subaortic stenosis is thought to be an acquired lesion, the aetiology of which may be a combination of factors which include an underlying genetic predisposition, turbulence in...
Mertens, L, Gewillig, M, Sutherland, G
We report a case of a 10-year-old child with nonobstructive hypertrophic cardiomyopathy in whom two-dimensional echocardiography showed asymmetric septal hypertrophy with a localized thickening in...
Van Pelt, N, Gillyns, H, Gewillig, M, Janssens, S
OBJECTIVE: To determine whether inhaled NO (iNO) can reduce pulmonary vascular resistance in adults with congenital heart disease and obstructive pulmonary hypertension or Eisenmenger syndrome....
We report the successful use of a cutting-balloon catheter in dilating stenoses in major systemic-to-pulmonary collateral arteries which had been resistant to high pressure balloons. After dilation...
A 14 year old girl presented with severe tricuspid regurgitation after she was diagnosed with "transient tricuspid regurgitation of the newborn". In the neonatal period she had presented with severe...
AIMS: This study compares the functional outcome and cardiorespiratory response to exercise, in patients who have undergone arterial switch for transposition of the great arteries, with normal...
Spontaneous closure of congenital coronary artery fistulas (2001)
Six cases of full spontaneous closure of congenital coronary artery fistulas, and one case of near closure, as seen by colour Doppler echocardiography, are presented. It is worth reconsidering the...
OBJECTIVES: Aneurysm formation after patch angioplasty for aortic coarctation is a frequent and potentially lethal complication, necessitating surgical reintervention. Although several mechanisms...
Brown, S, Eyskens, B, Gewillig, M
BACKGROUND: At present, a considerable number of patients survive who underwent an atrial switch operation for correction of complete transposition. Our study aimed to assess their long-term exercise...
Reybrouck, T, Eyskens, B, Mertens, L, Defoor, J, Daenen, W, Gewillig, M
Aims This study compares the functional outcome and cardiorespiratory response to exercise, in patients who have undergone arterial switch for transposition of the great arteries, with normal...
Giusti, S, Hausdorf, G, Qureshi, S, Tynan, M, Witsenburg, M, ...
In this review, we describe the experience from 13 European centres using the CardioSEAL and Starflex double umbrella devices to close interatrial communications within the oval fossa (so-called...
BACKGROUND: The surgical approach of neonates with a functionally univentricular heart, transposition of the great arteries and excessive pulmonary bloodflow remains a challenge. Pulmonary artery...
Dymarkowsky, S, Dumoulin, M, ...
Surgical repair of tetralogy of Fallot (TOF) with reconstruction of the right ventricular (RV) outflow tract invariably results in pulmonary regurgitation. Chronic pulmonary regurgitation has been...
Kuzo, R, Janssen, L, Celis, I, ...
Regular follow-up is required in patients with previous intervention for coarctation of the aorta to detect recoarctation or aneurysm formation. In this study we describe the findings encountered on...
Bull, C, Yates, R, Wright, D, Cullen, S, Gewillig, M, ...
BACKGROUND: We report the single-institution, long-term results of 358 patients with simple transposition of the great arteries surviving >30 days after a Mustard (n=226, 1965 to 1980) or Senning...
Gewillig, M, Eyskens, B, Dumoulin, M
Classic Fontan procedures, such as atriopulmonary connection or atrioventricular connection, are associated with right atrial dilatation and several late complications. Seven patients with...
Jashari, R, Eyskens, B, Gewillig, M, Dumoulin, M
OBJECTIVE: Pulmonary regurgitation after valveless repair of right ventricular outflow tract obstruction (RVOTO) results in progressive right ventricular (RV) dilatation and dysfunction in an...
Lawrenson, J, Brock, P, Doumoulin, M, Gewillig, M
Department of Congenital Cardiology, University Hospital Gasthuisberg, Kuleuven, B Leuven, Belgium. benedicte.eyskens@uz.kuleuven.ac.be
Schulze-Neick, I, Austenat, I, Eyskens, B, Dumoulin, M, ...
The purpose of this study was to analyse the ventilatory efficiency for carbon dioxide (CO2) in the assessment of exercise tolerance in patients with pulmonary hypertension. Two groups of patients...
Mid-term results of the Ross procedure (1998)
Jalali, H, Eyskens, B, Gewillig, M
METHODS: Fifty patients underwent a Ross operation between June 1991 and October 1996. Preoperative diagnosis was: congenital aortic valve disease (31 patients), complex left ventricular outflow...
Hagler, D J, Sauer, U, Somerville, J, Gewillig, M
OBJECTIVE: This multicenter study retrospectively analyzes the data on 114 patients with protein-losing enteropathy after Fontan-type surgery. Special attention was given to the different treatment...
Self expandable stents for relief of venous baffle obstruction after the Mustard operation (1998)
Eyskens, B, Stockx, L, Dumoulin, M, Gewillig, M
OBJECTIVE: Obstruction of the venous pathways after Mustard repair for transposition of the great arteries is associated with an increased risk of arrhythmia and sudden death. The purpose of this...
Medical treatment of neurocardiogenic syncope is insufficient in many cases. We have observed a therapeutic effect of repeated head-up tilt testing. Therefore, we have started a program of tilt...
Eyskens, B, Dumoulin, M, Gewillig, M
BACKGROUND: The natural history of major aortopulmonary collateral arteries (MAPCAs) in patients with pulmonary atresia and ventricular septal defect (PA-VSD) is frequently complicated by progressive...
The combination of coarctation of the aorta in the presence of severe aortic insufficiency poses a serious clinical problem. Although successful single- and two-stage repair for combined coarctation...
Factors influencing medium-term performance of right-sided cryopreserved homografts (1997)
BACKGROUND OF THE STUDY: Between February 1987 and December 1996, 187 children and young adults underwent right ventricular outflow tract (RVOT) reconstruction with aortic or pulmonary homografts....
Van Hoestenberghe, R, Gewillig, M
The management of the preterm fetus with hydrops due to complete congenital heart block is difficult. The outcome is frequently associated with significant morbidity and mortality. Two fetuses...
Schepers, D, Vinckx, J, Gewillig, M
The parameters used to assess aerobic exercise function by gas exchange are usually adjusted for body mass and are expressed as millilitres per minute per kilogram. In the case of obese children this...
Congenitally absent pulmonary veins--diagnostic pitfalls. Two case reports (1996)
Kalis, N N, Gie, R P, Dumoulin, M, Gewillig, M
Two patients with partial absence of the right and left pulmonary veins respectively are described. Congenitally absent pulmonary veins are a rare phenomenon and the diagnosis is often missed or...
Kalis, N, Weymans, M, Dumoulin, M, ...
In pediatric exercise testing, conventional measures of aerobic exercise function such as maximal O2 uptake or the ventilatory anaerobic threshold (VAT) use only one value for the assessment of...
Gewillig, M., Mertens, L., Moerman, P., Dumoulin, M.
Six children with idiopathic restrictive cardiomyopathy were evaluated. Electrocardiographs evaluation disclosed left atrial dilatation and repolarization abnormalities. Echocardiographic examination...
Comparison by computerized numeric modeling of energy losses in different Fontan connections (1995)
Sizaire, R, Montas, G, Purnode, B, ...
BACKGROUND: Different surgical techniques for creating a Fontan circulation can be used. The option of including an atrium in the circuit, or the technique used for connecting the caval veins to the...
Serial cardiorespiratory exercise testing in patients with congenital heart disease (1995)
Rogers, R, Weymans, M, Dumoulin, M, Vanhove, M, ...
Aerobic capacity of patients with different forms of congenital heart disease was serially evaluated in 79 patients and the evolution was correlated with the lesion and the level of daily activity....
Gewillig, M, ...
OBJECTIVES. This study used magnetic resonance imaging (MRI) to evaluate the morphology and pathophysiology of aneurysm formation after patch angioplasty for coarctation of the aorta. BACKGROUND....
Dopamine suppresses thyroid-stimulating hormone secretion in neonatal hypothyroidism (1995)
The infusion of dopamine, a hypophysiotropic catecholamine, which inhibits release of thyroid stimulating hormone (TSH), is the inotropic therapy of first choice in neonatal intensive care. Newborns...
Right ventricular outflow reconstruction with homografts (1995)
Narine, K, Goffin, Y, Gewillig, M
Ninety children and young adults underwent right ventricular outflow tract (RVOT) reconstruction with aortic or pulmonary homografts from May, 1989 to May, 1994. The patients were divided into three...
Department of Paediatric Cardiology, University Hospital, Gasthuisberg, Leuven, Belgium.
Weymans, M, Dumoulin, M, Gewillig, M
Sixty-nine patients (age 10 +/- 3.5 years, median 9.7 years) operated on for tetralogy of Fallot, underwent exercise testing 5.1 +/- 2.5 years after total correction. Aerobic capacity was assessed by...
ALCAPA syndrome: an example of chronic myocardial hypoperfusion? (1994)
OBJECTIVES. The purpose of this study was to evaluate functional variables and morphologic correlates of chronically hypoperfused myocardium before and after revascularization. BACKGROUND. Neonates...
Gewillig, M, Dumoulin, M, Van Der Hauwaert, L G
OBJECTIVE--To assess the cardiorespiratory response to graded exercise in patients after the Senning operation for transposition of the great arteries. DESIGN--Cross sectional study. Exercise...
Extended aortic root replacement with pulmonary autografts (1993)
The surgical relief of complex multilevel left ventricular outflow tract obstruction remains a challenging surgical problem. We present a new operation which combines the concepts of...
Gewillig, M, Bull, C, De Leval, M R, Deanfield, J E
Arrhythmia was compared between 40 consecutive patients (pts) undergoing atriopulmonary connection (APC) and 40 undergoing total cavopulmonary connection (TCPC), between 1986 and 1990. Patients were...
Prostaglandin E1 (PGE1) is an essential drug for infants with ductal-dependent congenital heart disease. Cortical hyperostosis of the long bones is one of the complications during and after PGE1...
Kilner, P, Gewillig, M, Bull, C
To understand better the contribution of a right atrium in a valveless atriopulmonary connection, we performed some basic hydrodynamic studies. Pulsation of a valveless chamber in a simple continuous...
New high-frequency catheter technique for His bundle ablation in dogs (1988)
Gewillig, M, Witters, E, ...
A new method is presented for the production of complete atrioventricular heart block. It consists of a special catheter, which is inserted into the right atrium via a femoral vein and positioned in...
Pediatric Department, University of Leuven, Belgium.
Delineation of the critical deletion region for congenital heart defects, on chromosome 8p23.1.
Devriendt, K, Matthijs, G, Van Dael, R, Gewillig, M, Eyskens, B, Hjalgrim, H, ...
Deletions in the distal region of chromosome 8p (del8p) are associated with congenital heart malformations. Other major manifestations include microcephaly, intrauterine growth retardation, mental...
Delineation of the critical deletion region for congenital heart defects, on chromosome 8p23.1.
Devriendt, K, Matthijs, G, Van Dael, R, Gewillig, M, Eyskens, B, Hjalgrim, H, ...
Deletions in the distal region of chromosome 8p (del8p) are associated with congenital heart malformations. Other major manifestations include microcephaly, intrauterine growth retardation, mental...
Gewillig, M, Wyse, R K, De Leval, M R, Deanfield, J E
OBJECTIVE--To study the incidence, predisposing factors, and clinical significance of arrhythmias early and late after the Fontan operation for congenital heart disease. PATIENTS AND METHODS--All 104...
Reybrouck, T, Gewillig, M, Dumoulin, M, Van Der Hauwaert, L G
OBJECTIVE--To assess the cardiorespiratory response to graded exercise in patients after the Senning operation for transposition of the great arteries. DESIGN--Cross sectional study. Exercise...
Transient neonatal tricuspid regurgitation: a Doppler echocardiographic study of three cases.
Gewillig, M, Dumoulin, M, Van Der Hauwaert, L G
Three patients with normal hearts and no pulmonary abnormality had neonatal tricuspid regurgitation causing cardiorespiratory distress and cyanosis. The signs of tricuspid regurgitation resolved over...
Brown, S, Eyskens, B, Mertens, L, Dumoulin, M, Gewillig, M
Background—The natural history of major aortopulmonary collateral arteries (MAPCAs) in patients with pulmonary atresia and ventricular septal defect (PA-VSD) is frequently complicated by...
Self expandable stents for relief of venous baffle obstruction after the Mustard operation
Brown, S, Eyskens, B, Mertens, L, Stockx, L, Dumoulin, M, Gewillig, M
Objective—Obstruction of the venous pathways after Mustard repair for transposition of the great arteries is associated with an increased risk of arrhythmia and sudden death. The purpose of this...
Spontaneous closure of congenital coronary artery fistulas
Schleich, J, Rey, C, Gewillig, M, Bozio, A
Six cases of full spontaneous closure of congenital coronary artery fistulas, and one case of near closure, as seen by colour Doppler echocardiography, are presented. It is worth reconsidering the...
Boshoff, D, Mertens, L, Gewillig, M
A 14 year old girl presented with severe tricuspid regurgitation after she was diagnosed with "transient tricuspid regurgitation of the newborn". In the neonatal period she had presented with severe...
Moons, P, De Volder, E, Budts, W, De Geest, S, Elen, J, Waeytens, K, ...
OBJECTIVE—To assess how much adults with congenital heart disease understand about their heart defect, its treatment, and the preventive measures necessary to avoid...
Budts, W, Van Pelt, N, Gillyns, H, Gewillig, M, Janssens, S
OBJECTIVE—To determine whether inhaled NO (iNO) can reduce pulmonary vascular resistance in adults with congenital heart disease and obstructive pulmonary hypertension or Eisenmenger...
Rheology of discrete subaortic stenosis
The discrete form of subaortic stenosis is thought to be an acquired lesion, the aetiology of which may be a combination of factors which include an underlying genetic predisposition, turbulence in...
Modified technique of stent fenestration of the atrial septum
Stümper, O, Gewillig, M, Vettukattil, J, Budts, W, Chessa, M, Chaudhari, M, ...
Objectives: To develop a modified technique for stenting the atrial septum in the treatment of patients with a failing Fontan operation or pulmonary hypertension.
Moons, P, Gewillig, M, Sluysmans, T, Verhaaren, H, Viart, P, Massin, M, ...
Objective: To assess long term outcome of patients who underwent Mustard or Senning repair for transposition of the great arteries up to 30 years earlier.
Renal and urological tract malformations caused by a 22q11 deletion.
Devriendt, K, Swillen, A, Fryns, J P, Proesmans, W, Gewillig, M
Swillen, A, Devriendt, K, Legius, E, Eyskens, B, Dumoulin, M, Gewillig, M, ...
We report data on a group of 37 VCFS patients with specific reference to their intelligence, behaviour, and social competence. Fifty five percent of the children had a borderline to normal IQ. Mental...
PTPN11 mutations in LEOPARD syndrome
Legius, E, Schrander-Stumpel, C, Schollen, E, Pulles-Heintzberg..., C, Gewillig, M, Fryns, J
Rauch, A, Devriendt, K, Koch, A, Rauch, R, Gewillig, M, Kraus, C, ...
Immediate and intermediate results of stent therapy for aortic coarctation
Honing-Hemmers, A.M., Van Putten, W.K., Gewillig, M., Mast, G., Talsma, M., Tanke, R., ...
Moons, P, Van Deyk, K, De Geest, S, Gewillig, M, Budts, W
Objective: To explore whether the severity of congenital heart disease is associated with the quality of life and perceived health status of adult patients.